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Target Details

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Name:Fibroblast growth factor receptor 3
Uniprot name:FGFR3_HUMAN
Accession Numbers:P22607 Q14308 Q16294 Q16608
EC-Number:2.7.10.1
Organism:Homo sapiens
Human
PDB IDs:1RY7
KEGG Pathways:show KEGG Pathways
Drugs:
NamePubChem IDSourceReferencesInteraction
1-((3-(Diethylamino)propyl)amino)-5,6,11-trimethyl-6H-pyrido(4,3-b)carbazo3068873BindingDB-show
2-aminopyrido[2,3-d]pyrimidin-7(8H)-one 195327866BindingDB-show
2-aminopyrido[2,3-d]pyrimidin-7(8H)-one 25327864BindingDB-show
2-aminopyrido[2,3-d]pyrimidin-7(8H)-one 285327875BindingDB-show
2-aminopyrido[2,3-d]pyrimidin-7(8H)-one 295327876BindingDB-show
2-aminopyrido[2,3-d]pyrimidin-7(8H)-one 305327877BindingDB-show
2-aminopyrido[2,3-d]pyrimidin-7(8H)-one 315327878BindingDB-show
2-aminopyrido[2,3-d]pyrimidin-7(8H)-one 385327885BindingDB-show
2-aminopyrido[2,3-d]pyrimidin-7(8H)-one 625327908BindingDB-show
2-aminopyrido[2,3-d]pyrimidin-7(8H)-one 685327914BindingDB-show
2-aminopyrido[2,3-d]pyrimidin-7(8H)-one 715327917BindingDB-show
3-((3R,4R)-4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperi9926791BindingDB-show
6-arylpyrido[2,3-d]pyrimidine deriv. 135328115BindingDB-show
6-arylpyrido[2,3-d]pyrimidine deriv. 325328134BindingDB-show
6-arylpyrido[2,3-d]pyrimidine deriv. 335328135BindingDB-show
6-arylpyrido[2,3-d]pyrimidine deriv. 475328149BindingDB-show
6-arylpyrido[2,3-d]pyrimidine deriv. 555328157BindingDB-show
6-arylpyrido[2,3-d]pyrimidine deriv. 565328158BindingDB-show
6-arylpyrido[2,3-d]pyrimidine deriv. 695328171BindingDB-show
7MP10062694BindingDB-show
9-HYDROXY-4-PHENYL-6H-PYRROLO[3,4-C]CARBAZOLE-1,3-DIONE4369491BindingDB-show
ABT-86911485656BindingDB-show
AC1NS3TB5328117BindingDB-show
AMG 70611667893BindingDB-show
AST-48711409972BindingDB-show
Bio2_0004136610353BindingDB-show
Canertinib156414BindingDB-show
CHEBI:1043465459219BindingDB-show
CHEBI:25992444329707BindingDB-show
CHEBI:30525144348997BindingDB-show
CHEBI:44418144409932BindingDB-show
CHEBI:54743644560358BindingDB-show
CHEBI:64749644358270BindingDB-show
CHEBI:64767744359680BindingDB-show
CHEBI:66834345481533BindingDB-show
CHEBI:66834445481534BindingDB-show
CHEMBL10145744330124BindingDB-show
CHEMBL1023019890746BindingDB-show
CHEMBL10234610907042BindingDB-show
CHEMBL10406711048367BindingDB-show
CHEMBL10696610905857BindingDB-show
CHEMBL108551124762205BindingDB-show
CHEMBL124070352945601BindingDB-show
CHEMBL12589810231458BindingDB-show
CHEMBL1315779927718BindingDB-show
CHEMBL19098011465545BindingDB-show
CHEMBL19191311155938BindingDB-show
CHEMBL19210111352215BindingDB-show
CHEMBL19313611328182BindingDB-show
CHEMBL19330610388612BindingDB-show
CHEMBL19449810073832BindingDB-show
CHEMBL19487211455031BindingDB-show
CHEMBL19539810436729BindingDB-show
CHEMBL19577111464544BindingDB-show
CHEMBL1958479982235BindingDB-show
CHEMBL19590311432911BindingDB-show
CHEMBL2013079916282BindingDB-show
CHEMBL21208444414322BindingDB-show
CHEMBL21374344414347BindingDB-show
CHEMBL21580316046126BindingDB-show
CHEMBL23333844432441BindingDB-show
CHEMBL29654044294299BindingDB-show
CHEMBL31655644330126BindingDB-show
CHEMBL31656744330125BindingDB-show
CHEMBL31776810015651BindingDB-show
CHEMBL31989411729539BindingDB-show
CHEMBL32333610457505BindingDB-show
CHEMBL32356444330102BindingDB-show
CHEMBL36531810478569BindingDB-show
CHEMBL37002311488852BindingDB-show
CHEMBL37051511419379BindingDB-show
CHEMBL37080811517688BindingDB-show
CHEMBL37137311374515BindingDB-show
CHEMBL37336511442803BindingDB-show
CHEMBL42587644390984BindingDB-show
CHEMBL43231444294644BindingDB-show
CHEMBL43273810738332BindingDB-show
CHEMBL5097744294903BindingDB-show
CHEMBL56892211723489BindingDB-show
CHEMBL57458845482700BindingDB-show
CHEMBL57461345482750BindingDB-show
CHEMBL57688723401001BindingDB-show
CHEMBL57698923400934BindingDB-show
CHEMBL57860110246246BindingDB-show
CHEMBL7518810602350BindingDB-show
CHEMBL8558944330049BindingDB-show
CHEMBL9839612424767BindingDB-show
CHEMBL9844744330158BindingDB-show
CHEMBL9904944330159BindingDB-show
CHEMBL9907715707182BindingDB-show
CHEMBL9935244330151BindingDB-show
CHEMBL9972444330203BindingDB-show
CHEMBL997439911005BindingDB-show
CHIR-26511656518BindingDB-show
CID 1151838911518389BindingDB-show
CP-7247149874913BindingDB-show
Dasatinib3062316BindingDB-show
Doramapimod156422BindingDB-show
Elliptinium42723BindingDB-show
Erlotinib176870BindingDB-show
Gefitinib123631BindingDB-show
GW-258011617559BindingDB-show
Hydroxyellipticine91643BindingDB-show
Imatinib Methansulfonate5291BindingDB-show
Intedanib9809715BindingDB-show
JAK Inhibitor I5494425BindingDB-show
Kinome_248146224684BindingDB-show
Kinome_291844444843BindingDB-show
Lapatinib ditosylate208908BindingDB-show
Lestaurtinib126565BindingDB-show
MLN805411712649BindingDB-show
n-hydroxy-l-tyrosinamide256524BindingDB-show
NSC61795247352BindingDB-show
NSC61804247358BindingDB-show
NVP-TAE68416038120BindingDB-show
Pazopanib10113978BindingDB-show
PD0898285328112BindingDB-show
PD089828 analog 125329117BindingDB-show
PD089828 analog 305329132BindingDB-show
PD089828 analog 315329133BindingDB-show
PD089828 analog 45329111BindingDB-show
PD1626285328125BindingDB-show
PD1662855311382BindingDB-show
PDSP1_0006835328127BindingDB-show
PI-1039884685BindingDB-show
PKC-4129829523BindingDB-show
pyrido(2,3-d)pyrimidine1401BindingDB-show
Roscovitine160355BindingDB-show
Ruboxistaurin153999BindingDB-show
RWJ-3872525330790BindingDB-show
S1018_Selleck9977819BindingDB-show
S1147_Selleck16007391BindingDB-show
S1526_Selleck24889392BindingDB-show
SB 2021905353940BindingDB-show
SB-4315424521392BindingDB-show
SNS-0323025986BindingDB-show
sorafenibum216239BindingDB-show
STAUROSPORINE44259BindingDB-show
staurosporine44299148BindingDB-show
SU-1481310138259BindingDB-show
Sunitinib5329102BindingDB-show
Tandutinib3038522BindingDB-show
Vandetanib3081361BindingDB-show
Vatalanib151194BindingDB-show
VX-6805494449BindingDB-show
VX-7453038525BindingDB-show
Synonyms:
CD333
FGFR-3
Fibroblast growth factor receptor 3
Similar targets:
Uniprot name% Sequence similarity% Sequence identity
Q99052_MOUSE94.892.4
FGFR2_HUMAN7665.8
FGFR1_HUMAN74.862
FGFR1_MOUSE74.662
FGFR4_HUMAN70.561
KIT_HUMAN38.424.7
Q6IQ28_HUMAN38.324.5
TYRO3_HUMAN37.424.9
CSF1R_HUMAN37.327.1
NTRK1_HUMAN37.125
DDR1_HUMAN34.122.3
BTK_HUMAN33.720.6
Q59F04_HUMAN33.522.6
RET_HUMAN33.424.2
FLT3_HUMAN33.322.5
PGFRA_HUMAN32.821.8
KSYK_HUMAN32.621.4
PGFRB_HUMAN32.421.5
KPCD1_MOUSE3218.4
SRC_RAT31.521.3
TOXA_PSEAE3118.9
ZAP70_HUMAN3119.1
KPCT_HUMAN30.919.3
BRAF_HUMAN30.819.6
VGFR1_HUMAN30.521
METE_ARATH30.517.8
KPCD1_HUMAN30.516.9
STA5B_HUMAN30.316.5
GCYA3_HUMAN30.217.4
Q59FL8_HUMAN29.919.8
Protein-Protein Interactions: