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Target Details

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Name:Fibroblast growth factor receptor 2
Uniprot name:FGFR2_HUMAN
Accession Numbers:P18443 P21802 Q01742 Q12922 Q14300 Q14301 Q14302 Q14303 Q14304 Q14305 Q14672 Q14718 Q14719 Q1KHY5 Q86YI4 Q96KL9 Q96KM0 Q96KM1 Q96KM2 Q9NZU2 Q9NZU3 Q9UD01 Q9UD02 Q9UIH3 Q9UIH4 Q9UIH5 Q9UIH6 Q9UIH7 Q9UIH8 Q9UM87 Q9UMC6 Q9UNS7 Q9UQH7 Q9UQH8 Q9UQH9 Q9UQI0
EC-Number:2.7.10.1
Organism:Homo sapiens
Human
PDB IDs:1DJS 1E0O 1EV2 1GJO 1II4 1IIL 1NUN 1OEC 1WVZ 2FDB 2PSQ 2PVF 2PVY 2PWL 2PY3 2PZ5 2PZP 2PZR 2Q0B 3B2T 3CAF 3CLY 3CU1 3DAR 3EUU
KEGG Pathways:show KEGG Pathways
Drugs:
NamePubChem IDSourceReferencesInteraction
1-Acyl-1H-[1,2,4]triazole-3,5-diamine Analogue 3c5330800BindingDB-show
1-Acyl-1H-[1,2,4]triazole-3,5-diamine Analogue 3f5330804BindingDB-show
3-((3R,4R)-4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperi9926791BindingDB-show
3-[4-(1-FORMYLPIPERAZIN-4-YL)-BENZYLIDENYL]-2-INDOLINONE1633DrugBank-show
4-ARYL-2-PHENYLAMINO PYRIMIDINE447622DrugBank-show
ABT-86911485656BindingDB-show
AMG 70611667893BindingDB-show
AST-48711409972BindingDB-show
Bio2_0004136610353BindingDB-show
Canertinib156414BindingDB-show
CHEBI:1043465459219BindingDB-show
CHEBI:25992444329707BindingDB-show
CHEBI:66834345481533BindingDB-show
CHEBI:66834445481534BindingDB-show
CHEMBL117295746898022BindingDB-show
CHEMBL124070352945601BindingDB-show
CHEMBL16742523022716BindingDB-show
CHEMBL16833544382047BindingDB-show
CHEMBL16939744382048BindingDB-show
CHEMBL16983723022671BindingDB-show
CHEMBL16985423022836BindingDB-show
CHEMBL17041544382259BindingDB-show
CHEMBL17051923022708BindingDB-show
CHEMBL17090723022732BindingDB-show
CHEMBL17116144382373BindingDB-show
CHEMBL1714139932979BindingDB-show
CHEMBL17150944382615BindingDB-show
CHEMBL17274644382310BindingDB-show
CHEMBL1913369863538BindingDB-show
CHEMBL21580316046126BindingDB-show
CHEMBL23068611562302BindingDB-show
CHEMBL27612523022691BindingDB-show
CHEMBL3523089850161BindingDB-show
CHEMBL35234223022656BindingDB-show
CHEMBL35253410113795BindingDB-show
CHEMBL35366844382361BindingDB-show
CHEMBL35388444382807BindingDB-show
CHEMBL35399144382037BindingDB-show
CHEMBL35422444382744BindingDB-show
CHEMBL35483023022619BindingDB-show
CHEMBL35489844382790BindingDB-show
CHEMBL35490244382806BindingDB-show
CHEMBL35543644382411BindingDB-show
CHEMBL41464344382531BindingDB-show
CHEMBL56988024883334BindingDB-show
CHEMBL57104024883287BindingDB-show
CHEMBL60079546232443BindingDB-show
CHEMBL60247146232555BindingDB-show
CHEMBL60247246232556BindingDB-show
CHIR-26511656518BindingDB-show
CP-7247149874913BindingDB-show
Dasatinib3062316BindingDB-show
Doramapimod156422BindingDB-show
Erlotinib176870BindingDB-show
Gefitinib123631BindingDB-show
GW-258011617559BindingDB-show
Imatinib Methansulfonate5291BindingDB-show
Intedanib9809715BindingDB-show
JAK Inhibitor I5494425BindingDB-show
Lapatinib ditosylate208908BindingDB-show
Lestaurtinib126565BindingDB-show
MLN805411712649BindingDB-show
Pazopanib10113978BindingDB-show
PI-1039884685BindingDB-show
PKC-4129829523BindingDB-show
Pyrazine-Pyridine Biheteroaryl 395330388BindingDB-show
Pyrazine-Pyridine Biheteroaryl 415330389BindingDB-show
Pyrazine-Pyridine Biheteroaryl 565330390BindingDB-show
Pyrazine-Pyridine Biheteroaryl 575330391BindingDB-show
Pyrazine-Pyridine Biheteroaryl 585330392BindingDB-show
Pyrazine-Pyridine Biheteroaryl 75330387BindingDB-show
Roscovitine160355BindingDB-show
Ruboxistaurin153999BindingDB-show
RWJ-3872525330790BindingDB-show
S1018_Selleck9977819BindingDB-show
S1147_Selleck16007391BindingDB-show
S1194_Selleck24756910BindingDB-show
S1363_Selleck11317348BindingDB-show
S1526_Selleck24889392BindingDB-show
SB 2021905353940BindingDB-show
SB-4315424521392BindingDB-show
SNS-0323025986BindingDB-show
sorafenibum216239BindingDB-show
STAUROSPORINE44259BindingDB-show
staurosporine44299148BindingDB-show
SU-1481310138259BindingDB-show
Sunitinib5329102BindingDB-show
Tandutinib3038522BindingDB-show
Vandetanib3081361BindingDB-show
Vatalanib151194BindingDB-show
VX-6805494449BindingDB-show
VX-7453038525BindingDB-show
Synonyms:
CD332
FGFR-2
Fibroblast growth factor receptor 2
Keratinocyte growth factor receptor 2
Similar targets:
Uniprot name% Sequence similarity% Sequence identity
FGFR1_MOUSE82.471.1
FGFR1_HUMAN82.471.5
Q99052_MOUSE76.166.1
FGFR3_HUMAN7665.8
FGFR4_HUMAN71.157.1
KIT_HUMAN39.425.2
Q6IQ28_HUMAN39.325.1
TYRO3_HUMAN38.224.7
NTRK1_HUMAN37.923.4
CSF1R_HUMAN35.422.3
Q59F04_HUMAN34.123
PGFRB_HUMAN34.122.8
ZAP70_HUMAN33.922
RET_HUMAN33.823.4
FLT3_HUMAN33.322.4
PGFRA_HUMAN32.822.7
KSYK_HUMAN32.720.9
KPCD1_MOUSE3217.7
LCK_HUMAN31.620.9
BTK_HUMAN31.619.3
KPCD_MOUSE31.219.8
DDR1_HUMAN30.919.8
PDXD1_HUMAN30.917.1
KPCT_HUMAN30.817.2
BRAF_HUMAN30.418.8
HCK_HUMAN30.219.1
KPC3_DROME30.217.7
MMP9_HUMAN3017.3
RELA_STREQ29.918
HEX_ADE0229.916.9
Protein-Protein Interactions: