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Target Details

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Name:Protein tyrosine kinase 2 beta
Uniprot name:FAK2_HUMAN
Accession Numbers:Q13475 Q14289 Q14290 Q16709
EC-Number:2.7.10.2
Organism:Homo sapiens
Human
PDB IDs:2FO6 3CC6 3ET7 3FZO 3FZP 3FZR 3FZS 3FZT 3GM1 3GM2 3GM3 3H3C
KEGG Pathways:show KEGG Pathways
Drugs:
NamePubChem IDSourceReferencesInteraction
3-((3R,4R)-4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperi9926791BindingDB-show
ABT-86911485656BindingDB-show
AMG 70611667893BindingDB-show
AST-48711409972BindingDB-show
Bosutinib5328940BindingDB-show
Canertinib156414BindingDB-show
CHEBI:1043465459219BindingDB-show
CHEBI:25992444329707BindingDB-show
CHEBI:66834345481533BindingDB-show
CHEBI:66834445481534BindingDB-show
CHEMBL108426925203958BindingDB-show
CHEMBL124070352945601BindingDB-show
CHEMBL45234144563136BindingDB-show
CHEMBL45234225229638BindingDB-show
CHEMBL45568044563103BindingDB-show
CHEMBL47031410000911BindingDB-show
CHEMBL47031644562948BindingDB-show
CHEMBL47031744562949BindingDB-show
CHEMBL47135721952457BindingDB-show
CHEMBL47152011502189BindingDB-show
CHEMBL47152644562903BindingDB-show
CHEMBL47169744562904BindingDB-show
CHEMBL47169844562905BindingDB-show
CHEMBL47221144562852BindingDB-show
CHEMBL48705744563060BindingDB-show
CHEMBL48722744563035BindingDB-show
CHEMBL48722844563036BindingDB-show
CHEMBL48722944563037BindingDB-show
CHEMBL48724621952403BindingDB-show
CHEMBL48808921952498BindingDB-show
CHEMBL48824744563062BindingDB-show
CHEMBL48844644562996BindingDB-show
CHEMBL50948525920890BindingDB-show
CHEMBL51115244562906BindingDB-show
CHEMBL51374421952489BindingDB-show
CHEMBL51455411612883BindingDB-show
CHEMBL51890544563059BindingDB-show
CHEMBL51941844563061BindingDB-show
CHEMBL52005911596788BindingDB-show
CHEMBL52988944562995BindingDB-show
CHEMBL56872945274825BindingDB-show
CHEMBL57018945275166BindingDB-show
CHEMBL57036545275165BindingDB-show
CHEMBL57036945275167BindingDB-show
CHEMBL57038045275055BindingDB-show
CHEMBL57038145275054BindingDB-show
CHEMBL57064345274824BindingDB-show
CHEMBL57064745274823BindingDB-show
CHEMBL57070645274615BindingDB-show
CHEMBL57084645274934BindingDB-show
CHEMBL57095511963310BindingDB-show
CHEMBL57223745274936BindingDB-show
CHEMBL58592744622837BindingDB-show
CHIR-26511656518BindingDB-show
CP-7247149874913BindingDB-show
Dasatinib3062316BindingDB-show
Doramapimod156422BindingDB-show
Erlotinib176870BindingDB-show
Gefitinib123631BindingDB-show
Genisterin5280961DrugBank-show
GW-258011617559BindingDB-show
hesperadin10142586BindingDB-show
Imatinib Methansulfonate5291BindingDB-show
Kinome_385711713159BindingDB-show
Lapatinib ditosylate208908BindingDB-show
Lestaurtinib126565BindingDB-show
MLN805411712649BindingDB-show
Pazopanib10113978BindingDB-show
PF-43139611598628BindingDB-show
PI-1039884685BindingDB-show
PKC-4129829523BindingDB-show
Roscovitine160355BindingDB-show
Ruboxistaurin153999BindingDB-show
RWJ-3872525330790BindingDB-show
S1018_Selleck9977819BindingDB-show
S1147_Selleck16007391BindingDB-show
S1526_Selleck24889392BindingDB-show
SB 2021905353940BindingDB-show
SB-4315424521392BindingDB-show
SNS-0323025986BindingDB-show
sorafenibum216239BindingDB-show
staurosporine44299148BindingDB-show
SU-1481310138259BindingDB-show
Sunitinib5329102BindingDB-show
Tandutinib3038522BindingDB-show
Vandetanib3081361BindingDB-show
Vatalanib151194BindingDB-show
VX-6805494449BindingDB-show
VX-7453038525BindingDB-show
Synonyms:
CADTK
CAK beta
Calcium-dependent tyrosine kinase
Cell adhesion kinase beta
FADK 2
Focal adhesion kinase 2
Proline-rich tyrosine kinase 2
Protein tyrosine kinase 2 beta
RAFTK
Related adhesion focal tyrosine kinase
Similar targets:
Uniprot name% Sequence similarity% Sequence identity
FAK1_HUMAN59.743.4
FAK1_MOUSE58.442.7
PLD1_RAT32.617.5
KINH_HUMAN31.918.3
PLD1_HUMAN31.917
O77690_BOVIN31.817.8
GUC2C_PIG31.617.5
CTNA1_MOUSE31.117.5
O75555_HUMAN31.117.6
Q59FL8_HUMAN30.719.1
ANPRA_HUMAN30.417.8
MALT_ECOLI30.416.6
EGFR_HUMAN29.317.4
Q59FK4_HUMAN29.318.8
AHR_RAT29.216.9
Q8IW08_HUMAN29.215.7
EPHB2_MOUSE29.117.1
AASS_HUMAN29.116.4
PLD2_MOUSE2917.3
GRIK1_HUMAN28.815.8
PDE6A_BOVIN28.715.4
ANPRA_RAT28.616.2
PDE6A_CANFA28.515.6
METE_ARATH28.215.4
PLD2_RAT28.216.6
MA2B1_CAVPO28.215.5
AHR_MOUSE28.215.9
ABL1_HUMAN28.117.7
PLD2_HUMAN28.116.3
ODO1_HUMAN28.115.4
Protein-Protein Interactions: