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Target Details

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Name:Coagulation factor XI
Uniprot name:FA11_HUMAN
Accession Numbers:P03951 Q4W5C2 Q9Y495
EC-Number:3.4.21.27
Organism:Homo sapiens
Human
PDB IDs:1XX9 1XXD 1XXF 1ZHM 1ZHP 1ZHR 1ZJD 1ZLR 1ZMJ 1ZML 1ZMN 1ZOM 1ZPB 1ZPC 1ZPZ 1ZRK 1ZSJ 1ZSK 1ZSL 1ZTJ 1ZTK 1ZTL 2F83 2FDA 2J8J 2J8L 3BG8
KEGG Pathways:show KEGG Pathways
Drugs:
NamePubChem IDSourceReferencesInteraction
4-[[1-methyl-5-[(2-methylbenzimidazol-1-yl)methyl]benzimidazol-2-yl]methylamino]benzenecarboximidamide445756BindingDB-show
AC1OAH346857700BindingDB-show
alpha-ketothiazole analogue 1016098890BindingDB-show
alpha-ketothiazole analogue 1116098891BindingDB-show
alpha-ketothiazole analogue 1216098892BindingDB-show
alpha-ketothiazole analogue 1323646328BindingDB-show
alpha-ketothiazole analogue 1416098894BindingDB-show
alpha-ketothiazole analogue 1511273795BindingDB-show
alpha-ketothiazole analogue 1623646329BindingDB-show
alpha-ketothiazole analogue 1716098895BindingDB-show
alpha-ketothiazole analogue 1816098896BindingDB-show
alpha-ketothiazole analogue 1916098897BindingDB-show
alpha-ketothiazole analogue 2016098898BindingDB-show
alpha-ketothiazole analogue 2116098899BindingDB-show
alpha-ketothiazole analogue 2216098900BindingDB-show
alpha-ketothiazole analogue 2316098901BindingDB-show
alpha-ketothiazole analogue 2416098902BindingDB-show
alpha-ketothiazole analogue 2516098903BindingDB-show
alpha-ketothiazole analogue 2616098904BindingDB-show
alpha-ketothiazole analogue 2716098905BindingDB-show
alpha-ketothiazole analogue 2816098906BindingDB-show
alpha-ketothiazole analogue 2916098907BindingDB-show
alpha-ketothiazole analogue 3016098908BindingDB-show
alpha-ketothiazole analogue 3116098909BindingDB-show
alpha-ketothiazole analogue 3216098910BindingDB-show
alpha-ketothiazole analogue 3316098911BindingDB-show
alpha-ketothiazole analogue 3416098912BindingDB-show
alpha-ketothiazole analogue 3516098913BindingDB-show
alpha-ketothiazole analogue 3616098914BindingDB-show
alpha-ketothiazole analogue 716098887BindingDB-show
alpha-ketothiazole analogue 816098888BindingDB-show
alpha-ketothiazole analogue 916098889BindingDB-show
BIBM10159953722BindingDB-show
BIBT08719600423BindingDB-show
CHEBI:26194644330487BindingDB-show
CHEBI:64627044330604BindingDB-show
CHEBI:64630344330461BindingDB-show
CHEBI:64630544330619BindingDB-show
CHEBI:64948018767498BindingDB-show
CHEBI:65146244461102BindingDB-show
CHEMBL117244949798729BindingDB-show
CHEMBL122185249864459BindingDB-show
CHEMBL122191324849206BindingDB-show
CHEMBL122191511271947BindingDB-show
CHEMBL122191649864483BindingDB-show
CHEMBL128892552942903BindingDB-show
CHEMBL128892652948297BindingDB-show
CHEMBL128986052941173BindingDB-show
CHEMBL128997852943592BindingDB-show
CHEMBL129007450908869BindingDB-show
CHEMBL20673644411666BindingDB-show
CHEMBL20705244411677BindingDB-show
CHEMBL20714344411551BindingDB-show
CHEMBL20734944411777BindingDB-show
CHEMBL20737244411779BindingDB-show
CHEMBL20745344411553BindingDB-show
CHEMBL20795144411585BindingDB-show
CHEMBL20828944411590BindingDB-show
CHEMBL20840544411549BindingDB-show
CHEMBL20859744411817BindingDB-show
CHEMBL20864544411808BindingDB-show
CHEMBL21043444411687BindingDB-show
CHEMBL21062444411818BindingDB-show
CHEMBL21063744411636BindingDB-show
CHEMBL21073144411800BindingDB-show
CHEMBL21192144416570BindingDB-show
CHEMBL21343444416548BindingDB-show
CHEMBL21513544416656BindingDB-show
CHEMBL21575044416546BindingDB-show
CHEMBL2339929954980BindingDB-show
CHEMBL23770544434815BindingDB-show
CHEMBL25540744453326BindingDB-show
CHEMBL25731544453328BindingDB-show
CHEMBL27150844453367BindingDB-show
CHEMBL37801144411821BindingDB-show
CHEMBL38045544411556BindingDB-show
CHEMBL38222944411550BindingDB-show
CHEMBL38300744411560BindingDB-show
CHEMBL38364511408882BindingDB-show
CHEMBL38418044416510BindingDB-show
CHEMBL39229744434835BindingDB-show
CHEMBL39412944434818BindingDB-show
CHEMBL39838011237163BindingDB-show
CHEMBL39959311351302BindingDB-show
CHEMBL40123544434809BindingDB-show
CHEMBL40304210275412BindingDB-show
CHEMBL40311311341176BindingDB-show
CHEMBL42578644416572BindingDB-show
CHEMBL43755524180463BindingDB-show
CHEMBL45057844432538BindingDB-show
CHEMBL50598644587263BindingDB-show
CHEMBL50624044587264BindingDB-show
CHEMBL50650144587290BindingDB-show
CHEMBL50650244587291BindingDB-show
CHEMBL50676944587292BindingDB-show
CHEMBL52711744587314BindingDB-show
CID 991821511399867BindingDB-show
CLAVATADINE A24881875BindingDB-show
CLAVATADINE B24881874BindingDB-show
gamma-Glutamylcysteinylglycine124886SuperTarget-show
Grassystatin A44255320BindingDB-show
Razaxaban204102BindingDB-show
Synonyms:
Coagulation factor XI
FXI
Plasma thromboplastin antecedent
PTA
Similar targets:
Uniprot name% Sequence similarity% Sequence identity
THRB_MOUSE35.824.2
THRB_HUMAN34.923.6
THRB_BOVIN34.724.3
B8ZX62_HUMAN34.223.4
TPA_HUMAN3423.2
FA10_HUMAN33.620.9
MASP2_RAT33.522.7
HGF_HUMAN33.320.2
PLMN_HUMAN31.921
FA10_BOVIN31.619.4
C1S_HUMAN31.619.6
FA9_HUMAN31.420.8
C1R_HUMAN31.320.3
UROK_MOUSE30.720
FA7_HUMAN30.619.7
SYFB_HUMAN30.617.4
CFAB_HUMAN30.519.7
Q5U2Q5_RAT3016.6
PROC_HUMAN29.620.2
UROK_HUMAN29.518.7
BTK_HUMAN29.415.5
ERO1_YEAST29.316.9
GLSK_RAT29.317.5
VMAT2_HUMAN29.316.1
RIR1_HUMAN28.816
SAP_HUMAN28.817.6
MDM2_HUMAN28.817.7
Q5PY49_HUMAN28.318.4
ACES_TORCA28.216.9
SPTC3_MOUSE28.215.4
Protein-Protein Interactions: