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Target Details

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Name:Carboxylesterase 2
Uniprot name:EST2_HUMAN
Accession Numbers:O00748 Q16859 Q5MAB8 Q7Z366 Q8IUP4 Q8TCP8
EC-Number:3.1.1.1
Organism:Homo sapiens
Human
PDB IDs:-
KEGG Pathways:show KEGG Pathways
Drugs:
NamePubChem IDSourceReferencesInteraction
(4-(Bromomethyl)phenyl)phenylethanedione87502BindingDB-show
1,10-Phenanthroline-5,6-dione72810BindingDB-show
1,2-Aceanthrylenedione316765BindingDB-show
1,2-bis(4-bromo-3-nitrophenyl)ethane-1,2-dione5038499BindingDB-show
1,2-bis(4-ethoxyphenyl)ethane-1,2-dione4369935BindingDB-show
1,2-bis(4-fluorophenyl)-2-hydroxyethanone103786BindingDB-show
1,2-bis(4-nitrophenyl)ethane-1,2-dione1812008BindingDB-show
1,2-Bis(4-trifluoromethylphenyl)-ethan-1,2-dione599378BindingDB-show
1,2-dinaphthalen-2-ylethane-1,2-dione3274712BindingDB-show
1,2-Indandione123358BindingDB-show
1,3-Cyclohexanedione10434BindingDB-show
1,3-dimethylcycloadipic ketone70945BindingDB-show
1,4-Bis(phenylglyoxaloyl)benzene137905BindingDB-show
1-(2,3,4,5,6-pentachlorophenyl)-2-(2,3,4,5,6-pentafluorophenyl)ethane-1,2-3527426BindingDB-show
1-(2-iodoethyl)indole-2,3-dione4135273BindingDB-show
1-(3,4-dimethylphenyl)-2-phenylethane-1,2-dione2427416BindingDB-show
1-(Hydroxymethyl)indole-2,3-dione39834BindingDB-show
1-(thiomorpholin-4-ylmethyl)indole-2,3-dione3531512BindingDB-show
1-Benzyl-1H-indole-2,3-dione264734BindingDB-show
1-Chloro-2,3-indoledione137777BindingDB-show
1-Dodecyl-1H-indole-2,3-dione1897797BindingDB-show
1-hexadecylindole-2,3-dione3772674BindingDB-show
1-Morpholin-4-ylmethyl-1H-indole-2,3-dione262696BindingDB-show
1-Phenyl-1,4-pentanedione136371BindingDB-show
1-Phenylisatin12884BindingDB-show
1-Piperidin-1-ylmethyl-1H-indole-2,3-dione262695BindingDB-show
2,2',4,4'-Tetrahydroxybenzil219592BindingDB-show
2,2'-Dichlorobenzil89076BindingDB-show
2,2'-Thenil275005BindingDB-show
2,2-Dimethoxy-2-phenylacetophenone90571BindingDB-show
2,3-Dioxo-1-indolineacetic acid43402BindingDB-show
2,3-dioxoindoline-7-carboxylic acid2779383BindingDB-show
2,3-HEPTANEDIONE60983BindingDB-show
2-(2,3-dioxoindol-1-yl)-N-(4-hydroxyphenyl)acetamide3329233BindingDB-show
2-Chloro-3',4'-dimethoxybenzil92036BindingDB-show
2-METHYL-1,3-CYCLOPENTANEDIONE13005BindingDB-show
2-nitrophenanthrene-9,10-dione94860BindingDB-show
3,3'-Dimethoxybenzil123493BindingDB-show
3,3'-Dinitrobenzil101375BindingDB-show
3,5,5-Trimethyl-1,2-cyclohexanedione93772BindingDB-show
3,5-Ditert-butylbenzo-1,2-quinone76915BindingDB-show
3-Methyl-1,2-cyclohexanedione3321360BindingDB-show
3-Methyl-1,2-cyclopentanedione61209BindingDB-show
4,4'-Dibromobenzil96430BindingDB-show
4,4'-Dichlorobenzil18946BindingDB-show
4,4'-Difluorobenzil123072BindingDB-show
4,4'-Dihydroxybenzil458204BindingDB-show
4,4'-Dimethoxybenzil71043BindingDB-show
4,4'-Dimethylbenzil76996BindingDB-show
4,5-dichloro-1H-indole-2,3-dione5139980BindingDB-show
4,6-Dichloro-1H-indole-2,3-dione251908BindingDB-show
4,7-Dichloroisatin2734793BindingDB-show
4,7-dimethyl-1H-indole-2,3-dione3264931BindingDB-show
4-Benzoylbenzoic acid69147BindingDB-show
4-Chloro-7-methyl-1H-indole-2,3-dione1810509BindingDB-show
4-Chlorodibenzoyl89801BindingDB-show
4-Chloroisatin96047BindingDB-show
4-Ethyl isatin13827082BindingDB-show
4-Nitrobenzil283893BindingDB-show
4290-72-62786143BindingDB-show
5,6-dichloro-1H-indole-2,3-dione11009341BindingDB-show
5,6-dimethylmorpholine-2,3-dione3469206BindingDB-show
5,7-Dichloroisatin80771BindingDB-show
5,7-Dimethylisatin38296BindingDB-show
5-(Trifluoromethoxy)isatin2732752BindingDB-show
5-Bromoisatin6889BindingDB-show
5-Chloro-7-methylisatin366710BindingDB-show
5-Chloroisatin87203BindingDB-show
5-Fluoroisatin236566BindingDB-show
5-Iodoisatin88695BindingDB-show
5-Methoxyisatin38333BindingDB-show
5-Methylisatin11840BindingDB-show
5-Nitroisatin4669250BindingDB-show
6-bromo-5-methyl-1H-indole-2,3-dione1718647BindingDB-show
6-Chloro-2-methoxyacridine-9-ylamine19080BindingDB-show
6-chloro-7-methyl-1H-indole-2,3-dione4513067BindingDB-show
6-Chloroisatin241331BindingDB-show
6-Ethyl isatin13827083BindingDB-show
7-Chloroisatin344135BindingDB-show
7-Fluoroisatin586418BindingDB-show
7-methoxyindoline-2,3-dione4088910BindingDB-show
7-Methylisatin14313BindingDB-show
7-Trifluoromethylisatin604575BindingDB-show
AC1LBXCL590628BindingDB-show
AC1M5V1J2385968BindingDB-show
AC1MBTQK2731127BindingDB-show
AC1MBV042731732BindingDB-show
AC1MBVDR2731902BindingDB-show
AC1MD6UA2784639BindingDB-show
AC1N9FPX4384851BindingDB-show
AC1NMC2C5004413BindingDB-show
AC1Q3HQA16786802BindingDB-show
Acenaphthenequinone6724BindingDB-show
Acetoacetaldehyde650BindingDB-show
Acetylacetone31261BindingDB-show
Acetylbenzoyl11363BindingDB-show
Acetylpropionyl11747BindingDB-show
AE-848/012910443477013BindingDB-show
Aethacridinum2017BindingDB-show
BAS 001171152305233BindingDB-show
BAS 011232233126152BindingDB-show
Benzil-based compound, 1211437501BindingDB-show
Benzil-based compound, 1311392969BindingDB-show
Benzil-based compound, 3324825630BindingDB-show
Benzoylphenylcarbinol8400BindingDB-show
Benzyl phenyl sulfone76561BindingDB-show
Benzyl sulfoxide12116BindingDB-show
Bipicolinoyl68115BindingDB-show
CHEMBL19067211245953BindingDB-show
CHEMBL19259211280423BindingDB-show
CHEMBL23528711806279BindingDB-show
CHEMBL24206722574214BindingDB-show
CHEMBL24228719377173BindingDB-show
CHEMBL24228844428837BindingDB-show
CHEMBL24229644428842BindingDB-show
CHEMBL24250644428843BindingDB-show
CHEMBL24272122574258BindingDB-show
CHEMBL24272244428839BindingDB-show
CHEMBL24276819971657BindingDB-show
CHEMBL24293044428840BindingDB-show
CHEMBL24293144428841BindingDB-show
CHEMBL24442544428828BindingDB-show
CHEMBL24442644428829BindingDB-show
CHEMBL24442744428831BindingDB-show
CHEMBL24442844428832BindingDB-show
CHEMBL24463044428834BindingDB-show
CHEMBL24463116745302BindingDB-show
CHEMBL24463244428836BindingDB-show
CHEMBL24463311043027BindingDB-show
CHEMBL37271611322015BindingDB-show
CHEMBL38888344428844BindingDB-show
CHEMBL39455744428830BindingDB-show
CHEMBL39480644428835BindingDB-show
CHEMBL39480715044210BindingDB-show
CHEMBL39501822574224BindingDB-show
CHEMBL39501922574246BindingDB-show
CHEMBL39697710868634BindingDB-show
CHEMBL39773944428838BindingDB-show
CHEMBL43737344428833BindingDB-show
CHEMBL57076445487242BindingDB-show
Cyclohexadienedione4650BindingDB-show
DCQX1845BindingDB-show
Dibenzoylmethane8433BindingDB-show
Dibenzyl sulfone69282BindingDB-show
Dibromosalicil10662BindingDB-show
Diphenylethanedione8651BindingDB-show
Diphenylmethanone3102BindingDB-show
Ethandione, bis[4-(dimethylamino)phenyl]-222570BindingDB-show
Furil68119BindingDB-show
FUROIN11100BindingDB-show
irinotecan hydrochloride60838SuperTarget2 PMIDsshow
Irinotecan hydrochloride74990SuperTarget2 PMIDsshow
Isatin-based compound, 254338240BindingDB-show
meso-Hydrobenzoin95447BindingDB-show
N-Acetylisatin11321BindingDB-show
N-Methylisatin16358BindingDB-show
NM18903001906162BindingDB-show
NSC127077277990BindingDB-show
o-Anisil222475BindingDB-show
o-Chloranil73252BindingDB-show
ortho-naphthoquinone10667BindingDB-show
p-Anisoin95415BindingDB-show
p-Methoxybenzil31494BindingDB-show
p-Methylbenzil75511BindingDB-show
Phenanthrenequinone6763BindingDB-show
Pseudoisatin7054BindingDB-show
ST0949552734800BindingDB-show
STK3686924350924BindingDB-show
STK3700403794313BindingDB-show
Tetrachloroparabenzoquinone8371BindingDB-show
Tetrahydroaminoacridine1935BindingDB-show
ZINC020257881713189BindingDB-show
ZINC020285823821945BindingDB-show
ZINC020997871755771BindingDB-show
ZINC022761101901244BindingDB-show
ZINC023598361972026BindingDB-show
ZINC025102452777298BindingDB-show
ZINC026686913542734BindingDB-show
ZINC027094432147394BindingDB-show
ZINC030708502731733BindingDB-show
ZINC03086180589576BindingDB-show
ZINC031302653114312BindingDB-show
ZINC043614572731126BindingDB-show
ZINC043618892731904BindingDB-show
Synonyms:
Carboxylesterase 2
CE-2
hCE-2
Similar targets:
Uniprot name% Sequence similarity% Sequence identity
Q53H57_HUMAN9695.9
Q6IPK9_HUMAN90.290
Q4G0E9_HUMAN9089.9
O35535_RAT80.969.9
O70177_RAT79.169.9
EST1_HUMAN61.345.7
EST1_RABIT60.845.2
EST1_PIG60.444.8
ACES_TORCA48.633.5
ACES_HUMAN48.532.7
ACES_MOUSE48.232.5
ACES_RAT4832.1
Q9JKC1_RAT46.632
CHLE_HUMAN45.931.4
CEL_BOVIN42.829.1
ACES_DROME41.526.4
Q6ED33_ASPNG39.325.4
LIP3_CANRU38.725.1
LIP1_CANRU3824.5
ACES_CHICK37.126.8
NRFA_WOLSU31.716.7
UGDH_HUMAN31.617.8
CP1A2_RAT31.518.6
CP1A2_MOUSE31.418.3
FAAH1_HUMAN31.117.6
MOT2_HUMAN30.816.1
ANGT_HUMAN30.818.3
TBB1_HUMAN30.717.7
Q96NU8_HUMAN30.718.4
AL3A2_HUMAN30.517.7
Protein-Protein Interactions:
No data available