Home
Drugs
Targets
Pathways
Ontologies
Cyp450s
Adv.search
Help/FAQ

Target Details

add
Name:Acyl coenzyme A:cholesterol acyltransferase
Uniprot name:EST1_RABIT
Accession Numbers:O77540 P12337
EC-Number:3.1.1.1
Organism:Oryctolagus cuniculus
Rabbit
PDB IDs:1K4Y
KEGG Pathways:-
Drugs:
NamePubChem IDSourceReferencesInteraction
(4-(Bromomethyl)phenyl)phenylethanedione87502BindingDB-show
1,2-bis(4-bromo-3-nitrophenyl)ethane-1,2-dione5038499BindingDB-show
1,3-Cyclohexanedione10434BindingDB-show
1,3-dimethylcycloadipic ketone70945BindingDB-show
1,4-Bis(phenylglyoxaloyl)benzene137905BindingDB-show
1-(2,3,4,5,6-pentachlorophenyl)-2-(2,3,4,5,6-pentafluorophenyl)ethane-1,2-3527426BindingDB-show
1-(2-iodoethyl)indole-2,3-dione4135273BindingDB-show
1-(3,4-dimethylphenyl)-2-phenylethane-1,2-dione2427416BindingDB-show
1-(Hydroxymethyl)indole-2,3-dione39834BindingDB-show
1-(thiomorpholin-4-ylmethyl)indole-2,3-dione3531512BindingDB-show
1-Benzyl-1H-indole-2,3-dione264734BindingDB-show
1-Chloro-2,3-indoledione137777BindingDB-show
1-Dodecyl-1H-indole-2,3-dione1897797BindingDB-show
1-hexadecylindole-2,3-dione3772674BindingDB-show
1-Morpholin-4-ylmethyl-1H-indole-2,3-dione262696BindingDB-show
1-Phenyl-1,4-pentanedione136371BindingDB-show
1-Phenylisatin12884BindingDB-show
1-Piperidin-1-ylmethyl-1H-indole-2,3-dione262695BindingDB-show
2,2',4,4'-Tetrahydroxybenzil219592BindingDB-show
2,2'-Dichlorobenzil89076BindingDB-show
2,2-Dimethoxy-2-phenylacetophenone90571BindingDB-show
2,3-Dioxo-1-indolineacetic acid43402BindingDB-show
2,3-dioxoindoline-7-carboxylic acid2779383BindingDB-show
2,3-HEPTANEDIONE60983BindingDB-show
2-(2,3-dioxoindol-1-yl)-N-(4-hydroxyphenyl)acetamide3329233BindingDB-show
2-Chloro-3',4'-dimethoxybenzil92036BindingDB-show
2-METHYL-1,3-CYCLOPENTANEDIONE13005BindingDB-show
3,3'-Dimethoxybenzil123493BindingDB-show
3,3'-Dinitrobenzil101375BindingDB-show
3,5,5-Trimethyl-1,2-cyclohexanedione93772BindingDB-show
3,5-Ditert-butylbenzo-1,2-quinone76915BindingDB-show
3-Methyl-1,2-cyclohexanedione3321360BindingDB-show
3-Methyl-1,2-cyclopentanedione61209BindingDB-show
4,4'-Dibromobenzil96430BindingDB-show
4,4'-Dichlorobenzil18946BindingDB-show
4,4'-Difluorobenzil123072BindingDB-show
4,4'-Dihydroxybenzil458204BindingDB-show
4,4'-Dimethoxybenzil71043BindingDB-show
4,4'-Dimethylbenzil76996BindingDB-show
4,5-dichloro-1H-indole-2,3-dione5139980BindingDB-show
4,6-Dichloro-1H-indole-2,3-dione251908BindingDB-show
4,7-Dichloroisatin2734793BindingDB-show
4,7-dimethyl-1H-indole-2,3-dione3264931BindingDB-show
4-Benzoylbenzoic acid69147BindingDB-show
4-Chloro-7-methyl-1H-indole-2,3-dione1810509BindingDB-show
4-Chlorodibenzoyl89801BindingDB-show
4-Chloroisatin96047BindingDB-show
4-Ethyl isatin13827082BindingDB-show
4-Nitrobenzil283893BindingDB-show
4-Piperidinopiperidine78607DrugBank-show
5,6-dichloro-1H-indole-2,3-dione11009341BindingDB-show
5,6-dimethylmorpholine-2,3-dione3469206BindingDB-show
5,7-Dichloroisatin80771BindingDB-show
5,7-Dimethylisatin38296BindingDB-show
5-(Trifluoromethoxy)isatin2732752BindingDB-show
5-Bromoisatin6889BindingDB-show
5-Chloro-7-methylisatin366710BindingDB-show
5-Chloroisatin87203BindingDB-show
5-Fluoroisatin236566BindingDB-show
5-Iodoisatin88695BindingDB-show
5-Methoxyisatin38333BindingDB-show
5-Methylisatin11840BindingDB-show
5-Nitroisatin4669250BindingDB-show
6-bromo-5-methyl-1H-indole-2,3-dione1718647BindingDB-show
6-chloro-7-methyl-1H-indole-2,3-dione4513067BindingDB-show
6-Chloroisatin241331BindingDB-show
6-Ethyl isatin13827083BindingDB-show
7-Chloroisatin344135BindingDB-show
7-Fluoroisatin586418BindingDB-show
7-methoxyindoline-2,3-dione4088910BindingDB-show
7-Methylisatin14313BindingDB-show
7-Trifluoromethylisatin604575BindingDB-show
AC1LBXCL590628BindingDB-show
AC1M5V1J2385968BindingDB-show
AC1MBTQK2731127BindingDB-show
AC1MBV042731732BindingDB-show
AC1MBVDR2731902BindingDB-show
AC1N9FPX4384851BindingDB-show
AC1NMC2C5004413BindingDB-show
AC1Q3HQA16786802BindingDB-show
Acetoacetaldehyde650BindingDB-show
Acetylacetone31261BindingDB-show
Acetylbenzoyl11363BindingDB-show
Acetylpropionyl11747BindingDB-show
BAS 001171152305233BindingDB-show
BAS 011232233126152BindingDB-show
Benzil-based compound, 1211437501BindingDB-show
Benzil-based compound, 1311392969BindingDB-show
Benzil-based compound, 3324825630BindingDB-show
Benzoylphenylcarbinol8400BindingDB-show
Benzyl phenyl sulfone76561BindingDB-show
Benzyl sulfoxide12116BindingDB-show
CHEMBL10088910091638BindingDB-show
CHEMBL10140310363695BindingDB-show
CHEMBL10148910048615BindingDB-show
CHEMBL10151710250601BindingDB-show
CHEMBL10192210476844BindingDB-show
CHEMBL1020269980090BindingDB-show
CHEMBL10204110251296BindingDB-show
CHEMBL16163810436278BindingDB-show
CHEMBL3167249886772BindingDB-show
CHEMBL31786310426365BindingDB-show
CHEMBL31882514969217BindingDB-show
CHEMBL42064110317246BindingDB-show
CHEMBL42082910094958BindingDB-show
CHEMBL43123510410283BindingDB-show
CHEMBL9797410476188BindingDB-show
CHEMBL983779981162BindingDB-show
CHEMBL984829930168BindingDB-show
CHEMBL986009980086BindingDB-show
CHEMBL9860210254777BindingDB-show
CHEMBL9864010366149BindingDB-show
CHEMBL9895310074202BindingDB-show
CHEMBL9905910386701BindingDB-show
CHEMBL9916210045765BindingDB-show
CHEMBL9916410321846BindingDB-show
Cyclohexadienedione4650BindingDB-show
DCQX1845BindingDB-show
Dibenzoylmethane8433BindingDB-show
Dibenzyl sulfone69282BindingDB-show
Dibromosalicil10662BindingDB-show
Diphenylethanedione8651BindingDB-show
Diphenylmethanone3102BindingDB-show
Ethandione, bis[4-(dimethylamino)phenyl]-222570BindingDB-show
Isatin-based compound, 254338240BindingDB-show
Lovastatin53232BindingDB-show
Mannose185698DrugBank-show
meso-Hydrobenzoin95447BindingDB-show
N-Acetylisatin11321BindingDB-show
N-Methylisatin16358BindingDB-show
NM18903001906162BindingDB-show
NSC127077277990BindingDB-show
o-Chloranil73252BindingDB-show
p-Anisoin95415BindingDB-show
p-Methoxybenzil31494BindingDB-show
p-Methylbenzil75511BindingDB-show
Pseudoisatin7054BindingDB-show
STK3686924350924BindingDB-show
STK3700403794313BindingDB-show
Tetrachloroparabenzoquinone8371BindingDB-show
ZINC020257881713189BindingDB-show
ZINC020285823821945BindingDB-show
ZINC020997871755771BindingDB-show
ZINC022761101901244BindingDB-show
ZINC025102452777298BindingDB-show
ZINC026686913542734BindingDB-show
ZINC027094432147394BindingDB-show
ZINC030708502731733BindingDB-show
ZINC03086180589576BindingDB-show
ZINC031302653114312BindingDB-show
ZINC043614572731126BindingDB-show
ZINC043618892731904BindingDB-show
Synonyms:
Acyl coenzyme A:cholesterol acyltransferase
Liver carboxylesterase 1
Similar targets:
Uniprot name% Sequence similarity% Sequence identity
EST1_HUMAN90.781.1
EST1_PIG86.675.8
O35535_RAT6345.4
EST2_HUMAN60.845.2
O70177_RAT58.742.5
Q53H57_HUMAN58.543.5
Q6IPK9_HUMAN55.541.4
Q4G0E9_HUMAN55.441.3
ACES_TORCA47.831.4
Q9JKC1_RAT44.530.5
ACES_MOUSE43.529.3
CEL_BOVIN43.229.3
ACES_HUMAN43.128.8
ACES_RAT43.128.1
CHLE_HUMAN41.528.4
ACES_DROME39.725.5
Q6ED33_ASPNG38.424.6
LIP3_CANRU36.222.8
ACES_CHICK36.125.1
LIP1_CANRU34.724.5
LAC1_TRAVI31.719.6
GGT_ECOLI31.419.9
PDIA1_HUMAN31.318.6
PUCL_BACSB31.217.6
IIGP1_MOUSE30.716
Q940G2_ARATH30.617.6
GLSL_RAT30.617.9
GATB_HUMAN30.516.3
ATPB_RAT30.317.1
BLS_STRCL3017.2
Protein-Protein Interactions:
No data available