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Target Details

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Name:Ephrin type-A receptor 2
Uniprot name:EPHA2_HUMAN
Accession Numbers:P29317 Q8N3Z2
EC-Number:2.7.10.1
Organism:Homo sapiens
Human
PDB IDs:1MQB 2E8N 2K9Y 3C8X 3CZU 3FL7 3HEI 3HPN
KEGG Pathways:show KEGG Pathways
Drugs:
NamePubChem IDSourceReferencesInteraction
2,4-dianilino pyrimidine, 225138012BindingDB-show
3-((3R,4R)-4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperi9926791BindingDB-show
ABT-86911485656BindingDB-show
ADENYLYL IMIDODIPHOSPHATE33113DrugBank-show
AMG 70611667893BindingDB-show
AST-48711409972BindingDB-show
Canertinib156414BindingDB-show
CHEBI:1043465459219BindingDB-show
CHEBI:25992444329707BindingDB-show
CHEBI:66834345481533BindingDB-show
CHEBI:66834445481534BindingDB-show
CHEMBL108119811755812BindingDB-show
CHEMBL117295746898022BindingDB-show
CHEMBL124070352945601BindingDB-show
CHEMBL127148050899556BindingDB-show
CHEMBL127153252945752BindingDB-show
CHEMBL127153352945753BindingDB-show
CHEMBL127164152944268BindingDB-show
CHEMBL127164252941849BindingDB-show
CHEMBL127169252947964BindingDB-show
CHEMBL23333844432441BindingDB-show
CHEMBL4515239917045BindingDB-show
CHEMBL46546544570553BindingDB-show
CHEMBL48196844570599BindingDB-show
CHEMBL48196944570600BindingDB-show
CHEMBL51764744570554BindingDB-show
CHEMBL56651544478401BindingDB-show
CHEMBL56892211723489BindingDB-show
CHEMBL57688723401001BindingDB-show
CHEMBL57698923400934BindingDB-show
CHEMBL57860110246246BindingDB-show
CHEMBL60079546232443BindingDB-show
CHEMBL60247146232555BindingDB-show
CHEMBL60247246232556BindingDB-show
CHIR-26511656518BindingDB-show
CP-7247149874913BindingDB-show
Dasatinib3062316BindingDB-show
Dasatinib3062316DrugBank-show
Doramapimod156422BindingDB-show
dorsomorphin11524144BindingDB-show
Erlotinib176870BindingDB-show
Gefitinib123631BindingDB-show
GW-258011617559BindingDB-show
Imatinib Methansulfonate5291BindingDB-show
Kinome_248146224684BindingDB-show
Kinome_291844444843BindingDB-show
Kinome_71446886323BindingDB-show
Lapatinib ditosylate208908BindingDB-show
Lestaurtinib126565BindingDB-show
MLN805411712649BindingDB-show
nchembio859-comp1644243BindingDB-show
Pazopanib10113978BindingDB-show
PI-1039884685BindingDB-show
PKC-4129829523BindingDB-show
pyrazolo[1,5-a]pyrimidine 4h5329453BindingDB-show
Roscovitine160355BindingDB-show
Ruboxistaurin153999BindingDB-show
RWJ-3872525330790BindingDB-show
S1018_Selleck9977819BindingDB-show
S1147_Selleck16007391BindingDB-show
S1526_Selleck24889392BindingDB-show
SB 2021905353940BindingDB-show
SB-4315424521392BindingDB-show
SNS-0323025986BindingDB-show
sorafenibum216239BindingDB-show
STAUROSPORINE44259BindingDB-show
staurosporine44299148BindingDB-show
SU-1481310138259BindingDB-show
Sunitinib5329102BindingDB-show
Tandutinib3038522BindingDB-show
Vandetanib3081361BindingDB-show
Vatalanib151194BindingDB-show
VX-6805494449BindingDB-show
VX-7453038525BindingDB-show
Synonyms:
Ephrin type-A receptor 2
Epithelial cell kinase
Tyrosine-protein kinase receptor ECK
Similar targets:
Uniprot name% Sequence similarity% Sequence identity
EPHB2_MOUSE63.947.6
EPHB1_HUMAN63.147.6
PGFRA_HUMAN34.420.5
EGFR_HUMAN32.820
TYRO3_HUMAN32.421
EGFR_MOUSE32.119.1
FLT3_HUMAN31.520.3
BRAF_HUMAN31.319.4
Q99052_MOUSE30.919.6
PGFRB_HUMAN30.918.8
JAK3_RAT30.720.4
JAK2_HUMAN30.318.4
VGFR3_HUMAN29.618
JAK3_HUMAN29.519.2
FGFR1_MOUSE29.419
FGFR3_HUMAN29.318.9
CSF1R_HUMAN29.218.4
ITK_HUMAN29.218.8
FGFR1_HUMAN29.218.8
YES_HUMAN2919.6
JAK3_MOUSE28.818.8
VGFR1_HUMAN28.816.4
PTN4_HUMAN28.717
ERBB4_HUMAN28.618
NNTM_BOVIN28.417.4
SRC_HUMAN28.320.1
PK3CG_HUMAN28.215.6
MCR_HUMAN28.216.6
FGFR4_HUMAN28.219.3
BTK_HUMAN28.219.2
Protein-Protein Interactions: