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Target Details

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Name:Dihydrofolate reductase
Uniprot name:DYR_LACCA
Accession Numbers:P00381
EC-Number:1.5.1.3
Organism:Lactobacillus casei
PDB IDs:1AO8 1BZF 1DIS 1DIU 1LUD 2HM9 2HQP 3DFR
KEGG Pathways:-
Drugs:
NamePubChem IDSourceReferencesInteraction
10-Deazaaminopterin100516BindingDB-show
10-EdAM54586BindingDB-show
10-Propargylaminopterin100093BindingDB-show
2,4-DIAMINO-5-(3,4,5-TRIMETHOXY-BENZYL)-PYRIMIDIN-1-IUM6398511DrugBank-show
2,4-Diamino-6-benzyl-5-methylthieno[2,3-d]pyrimidine457382BindingDB-show
5-Benzyl-6-methylthieno[2,3-d]pyrimidine-2,4-diamine457384BindingDB-show
5-Methyl-6-phenylthieno[2,3-d]pyrimidine-2,4-diamine457380BindingDB-show
AC1L1FXT3439BindingDB-show
AC1L74LG329367BindingDB-show
AC1L8FKC425380BindingDB-show
AC1L9UK3456250BindingDB-show
AC1L9YB8504022BindingDB-show
AC1L9ZWY479088BindingDB-show
AC1LA0LB479412BindingDB-show
AC1LA0LE479413BindingDB-show
AC1LA0LT479418BindingDB-show
AC1LAHT8468709BindingDB-show
AC1LAHTB468710BindingDB-show
AC1LAHTE468711BindingDB-show
AC1LAHTH468712BindingDB-show
AIDS0936482440BindingDB-show
BRODIMOPRIM-4,6-DICARBOXYLATE5287754DrugBank-show
CB 37171405BindingDB-show
CHEBI:17528944294491BindingDB-show
CHEBI:17563944294631BindingDB-show
CHEBI:17564044294633BindingDB-show
CHEBI:17566844294647BindingDB-show
CHEBI:17599044294793BindingDB-show
CHEMBL1066999889551BindingDB-show
CHEMBL12463113912572BindingDB-show
CHEMBL125476715618966BindingDB-show
CHEMBL125485546918149BindingDB-show
CHEMBL125493946913624BindingDB-show
CHEMBL125502346913625BindingDB-show
CHEMBL125502452942279BindingDB-show
CHEMBL17087419427206BindingDB-show
CHEMBL17148010073043BindingDB-show
CHEMBL17327113912571BindingDB-show
CHEMBL19263224737646BindingDB-show
CHEMBL19327510456691BindingDB-show
CHEMBL22327911744008BindingDB-show
CHEMBL2359444458639BindingDB-show
CHEMBL2378444458576BindingDB-show
CHEMBL26789044308904BindingDB-show
CHEMBL27973221795893BindingDB-show
CHEMBL28014544458588BindingDB-show
CHEMBL28640044279131BindingDB-show
CHEMBL29081513942163BindingDB-show
CHEMBL29986344295279BindingDB-show
CHEMBL3171344279426BindingDB-show
CHEMBL3188744279452BindingDB-show
CHEMBL3192444279152BindingDB-show
CHEMBL32138844336792BindingDB-show
CHEMBL3304544281305BindingDB-show
CHEMBL3381544281312BindingDB-show
CHEMBL34026944355725BindingDB-show
CHEMBL3491812919900BindingDB-show
CHEMBL36530744398808BindingDB-show
CHEMBL3663944285361BindingDB-show
CHEMBL3667413942162BindingDB-show
CHEMBL4105622708989BindingDB-show
CHEMBL4215921473788BindingDB-show
CHEMBL4308729911146BindingDB-show
CHEMBL4468421147532BindingDB-show
CHEMBL4861944294862BindingDB-show
CHEMBL4902244295580BindingDB-show
CHEMBL4965144294853BindingDB-show
CHEMBL6638913844742BindingDB-show
CHEMBL6686414186429BindingDB-show
CHEMBL6901613844740BindingDB-show
CHEMBL982444266408BindingDB-show
CHEMBL997344266395BindingDB-show
CID 1182653311826533BindingDB-show
CID 986792110478474BindingDB-show
CID 99322769932276BindingDB-show
Dpmabg158351BindingDB-show
Dpmmabg158376BindingDB-show
Edatrexate6917908BindingDB-show
GPB5288461BindingDB-show
Lometrexol1773BindingDB-show
Methylaminopterin4112BindingDB-show
Methylaminopterinum126941BindingDB-show
Methylaminopterinum72440BindingDB-show
n-(4-{[(2,4-diaminofuro[2,3-d]pyrimidin-5-yl)methyl]amino}benzoyl)glutamic468708BindingDB-show
N6-[(2,5-dimethoxyphenyl)methyl]-N6-methylpyrido[5,6-e]pyrimidine-2,4,6-triamine444617BindingDB-show
NSC330776332634BindingDB-show
Pemetrexed394493BindingDB-show
Pemetrexed446556BindingDB-show
Piritrexim Isethionate54369BindingDB-show
PY 821457381BindingDB-show
PY 826457383BindingDB-show
PY831456251BindingDB-show
Sulfamethoprim5578BindingDB-show
Synonyms:
Dihydrofolate reductase
Similar targets:
Uniprot name% Sequence similarity% Sequence identity
DYR_ECOLI49.729.7
DYR_CHICK47.126.2
DYR_HUMAN45.526.5
DYR_CANAL4226.3
DYR_MYCTU40.328
DYR_PNECA38.121.9
FAE_METEA35.421.2
T2B2_BACSU33.219.3
FABPI_RAT31.817.9
P83826_THETH31.822.2
TPPC3_HUMAN31.617.7
HBG1_PANTR31.520.7
Q97YX6_SULSO31.516
AZUR_PSEAE31.120
KCSA_STRLI31.118.9
RIFK_HUMAN30.814.9
B8QUG7_ECOLX30.817.9
YCEI_ECOLI30.520
FABP7_HUMAN30.518.6
O52806_AMYOR30.418
Q47764_ENTFC30.419.2
ISG20_HUMAN30.420.7
LYS_BPT430.319.7
HBB_HORSE30.219.6
RL9_DEIRA30.120.4
TXD12_HUMAN3016.5
CBIT_METTH3019.8
Q7CL96_YERPE3017.1
SOMA_HUMAN29.715.1
VPS21_YEAST29.716.2
Protein-Protein Interactions:
No data available