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Target Details

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Name:Dihydrofolate reductase
Uniprot name:DYR_CANAL
Accession Numbers:O59840 P22906
EC-Number:1.5.1.3
Organism:Candida albicans
Yeast
PDB IDs:1AI9 1AOE 1IA1 1IA2 1IA3 1IA4 1M78 1M79 1M7A
KEGG Pathways:-
Drugs:
NamePubChem IDSourceReferencesInteraction
1-ynyl]-6-methylpyrimidine25093367BindingDB-show
11F25195365BindingDB-show
2,4-Diamino-25093363BindingDB-show
2-(N-morpholiniumyl)ethanesulfonate4478249DrugBank-show
5-(4-METHOXYPHENOXY)-2,4-QUINAZOLINEDIAMINE447098DrugBank-show
5-(4-methylphenyl)sulfanylquinazoline-2,4-diamine446245BindingDB-show
5-(4-methylphenyl)sulfanylquinazoline-2,4-diamine446245DrugBank-show
5-(4-morpholin-4-ylphenyl)sulfanylquinazoline-2,4-diamine3534BindingDB-show
5-(4-morpholin-4-ylphenyl)sulfanylquinazoline-2,4-diamine3534DrugBank-show
5-CHLORYL-2,4,6-QUINAZOLINETRIAMINE152217DrugBank-show
5-PHENYLSULFANYL-2,4-QUINAZOLINEDIAMINE446244BindingDB-show
5-PHENYLSULFANYL-2,4-QUINAZOLINEDIAMINE446244DrugBank-show
5-[4-TERT-BUTYLPHENYLSULFANYL]-2,4-QUINAZOLINEDIAMINE3537BindingDB-show
5-[4-TERT-BUTYLPHENYLSULFANYL]-2,4-QUINAZOLINEDIAMINE3537DrugBank-show
53R25093369BindingDB-show
53T44144379BindingDB-show
5WB45482186BindingDB-show
6-Methyl-5-[(3r)-3-(3,4,5-Trimethoxyphenyl)pent-1-Yn-1-Yl]pyrimidine-2,4-D45482254BindingDB-show
AC1LAG62467889BindingDB-show
AC1LAG65467890BindingDB-show
AC1LAG68467891BindingDB-show
AC1LAG6B467892BindingDB-show
AC1LAG6E467893BindingDB-show
AC1LAG6H467894BindingDB-show
AC1LAG6K467895BindingDB-show
AC1LAG6N467896BindingDB-show
AC1LAG6Q467897BindingDB-show
AC1LAG6T467898BindingDB-show
AC1LAG6W467899BindingDB-show
AC1LAG6Z467900BindingDB-show
AC1LAG72467901BindingDB-show
AC1LAG75467902BindingDB-show
AC1LAG78467903BindingDB-show
AC1LAG7B467904BindingDB-show
AC1LAG7E467905BindingDB-show
CHEMBL21962416110323BindingDB-show
CHEMBL21988916110338BindingDB-show
CHEMBL22015916110337BindingDB-show
CHEMBL22093616110329BindingDB-show
CHEMBL22093716110341BindingDB-show
CHEMBL22117216110328BindingDB-show
CHEMBL22246116110326BindingDB-show
CHEMBL22330116110344BindingDB-show
CHEMBL22356916110334BindingDB-show
CHEMBL38444316110339BindingDB-show
CHEMBL45772625093364BindingDB-show
CHEMBL45790525093365BindingDB-show
CHEMBL45790625093366BindingDB-show
CHEMBL45882925093368BindingDB-show
CHEMBL45917825093370BindingDB-show
CHEMBL48556925093362BindingDB-show
CHEMBL52035825093361BindingDB-show
CHEMBL57248525187898BindingDB-show
CHEMBL57271745481893BindingDB-show
CHEMBL57285645482216BindingDB-show
CHEMBL57307545482172BindingDB-show
CHEMBL57307645482183BindingDB-show
CHEMBL57307744144380BindingDB-show
CHEMBL57311745482206BindingDB-show
CHEMBL57340645481948BindingDB-show
CHEMBL57340745481949BindingDB-show
CHEMBL57381045482185BindingDB-show
CHEMBL57388045481871BindingDB-show
CHEMBL57425845482214BindingDB-show
CHEMBL57428845482142BindingDB-show
CHEMBL57432945481939BindingDB-show
CHEMBL57433525187895BindingDB-show
CHEMBL57433645481944BindingDB-show
CHEMBL57455345481945BindingDB-show
CHEMBL57455945481879BindingDB-show
CHEMBL57456345481900BindingDB-show
CHEMBL57456445481953BindingDB-show
CHEMBL57478945481954BindingDB-show
CHEMBL57494945482171BindingDB-show
CHEMBL57495145482227BindingDB-show
CHEMBL57495245482228BindingDB-show
CHEMBL57500945481880BindingDB-show
CHEMBL57517645482182BindingDB-show
CHEMBL57517745482184BindingDB-show
CHEMBL57518545482247BindingDB-show
CHEMBL57519445482147BindingDB-show
CHEMBL57521725195124BindingDB-show
CHEMBL57521844144378BindingDB-show
CHEMBL57522345481950BindingDB-show
CHEMBL57539445482238BindingDB-show
CHEMBL57541045482207BindingDB-show
CHEMBL57562645482199BindingDB-show
CHEMBL57562745482249BindingDB-show
CHEMBL57563245482259BindingDB-show
CHEMBL57697644223989BindingDB-show
CHEMBL57779045481957BindingDB-show
CHEMBL57842425187897BindingDB-show
CHEMBL57864845482197BindingDB-show
CHEMBL58284345481892BindingDB-show
CHEMBL58288145482162BindingDB-show
CHEMBL58318445482248BindingDB-show
CHEMBL58357045481901BindingDB-show
CHEMBL58370445482215BindingDB-show
CHEMBL58416445482223BindingDB-show
CHEMBL58438545482143BindingDB-show
CHEMBL58439045481878BindingDB-show
CHEMBL58439125195125BindingDB-show
CHEMBL58536345482243BindingDB-show
CHEMBL59119145482198BindingDB-show
Diaminopyrrolo[3,2-f]quinazoline der.177894BindingDB-show
DM624456183BindingDB-show
EKB25138225BindingDB-show
GW3451881BindingDB-show
N2225058133BindingDB-show
NSC3395785384532BindingDB-show
Piritrexim Isethionate54369BindingDB-show
Propargyl inhibitor, 1525138222BindingDB-show
Propargyl inhibitor, 1625138223BindingDB-show
Propargyl inhibitor, 1825138224BindingDB-show
Sulfamethoprim5578BindingDB-show
Trimetrexate5583BindingDB-show
Synonyms:
Dihydrofolate reductase
Similar targets:
Uniprot name% Sequence similarity% Sequence identity
DYR_PNECA53.934.6
DYR_CHICK50.234
DYR_HUMAN50.231.9
DYR_ECOLI44.328.9
DYR_MYCTU42.224.1
DYR_LACCA4226.3
KADC_MAIZE38.418.1
XPT_BACSU38.217.3
COAD_BACSU36.515.5
YPT7_YEAST34.819.3
NCS1_RAT34.717.4
PYRI_ECOLI34.618
PYRI_ECOL634.618
PYRI_ECO5734.618
Q9BHB0_9DIPT34.418.9
KCY_HUMAN34.417.9
SEC4_YEAST33.820.8
TORD_SHEMA33.718.1
PPAL_YEAST33.619
CO8G_HUMAN33.316
Q9RP17_NEIME33.314.3
IFNB_HUMAN33.214.9
Q6GDS0_STAAR32.917.3
LACB_PIG32.916.9
DAPB_THEMA32.714.7
NDUB6_HUMAN32.718
Q2QJL3_ACEAC32.215
MAF_BACSU32.116.7
COMB_CLOAB32.115.5
Q9NAV8_9ANNE32.116.3
Protein-Protein Interactions:
No data available