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Name:Bifunctional dihydrofolate reductase-thymidylate synthase
Uniprot name:DRTS_PLAFK
Accession Numbers:P13922 Q27734
EC-Number:-
Organism:isolate K1 / Thailand
Plasmodium falciparum
PDB IDs:1J3I 1J3J 1J3K 3DG8 3DGA
KEGG Pathways:-
Drugs:
NamePubChem IDSourceReferencesInteraction
(3-hydrazinylquinoxalin-2-yl)hydrazine155947BindingDB-show
1,3,5-Triazine-2,4-diamine, 1,6-dihydro-6,6-dimethyl-1-phenyl-19931BindingDB-show
2,4-Diamino-5-(3-methoxy-4-benzyloxybenzyl)pyrimidine463124BindingDB-show
2,4-Diamino-5-(3-methoxy-4-ethoxybenzyl)pyrimidine463109BindingDB-show
2,4-Diamino-5-(4-methoxybenzyl)pyrimidine88462BindingDB-show
2,4-Diamino-6-ethyl-5-phenylpyrimidine93114BindingDB-show
5-(4-bromophenyl)-6-ethylpyrimidine-2,4-diamine134626BindingDB-show
AC1L1TU035510BindingDB-show
AC1L7FUM309795BindingDB-show
AC1L8VI2433474BindingDB-show
AC1LA7IK463126BindingDB-show
AC1LA7IQ463128BindingDB-show
AC1MJ80Y3132813BindingDB-show
AC1NWE6S5703862BindingDB-show
AC1NWF7S5704385BindingDB-show
AC1NZH755933236BindingDB-show
Benzylpyrimidine der463131BindingDB-show
BRL 6231hydrochloride121750BindingDB-show
BRN 0146163134761BindingDB-show
BRN 0172545204821BindingDB-show
CHEMBL11548311383435BindingDB-show
CHEMBL11820211339941BindingDB-show
CHEMBL11842511361827BindingDB-show
CHEMBL11858111403887BindingDB-show
CHEMBL11860211360523BindingDB-show
CHEMBL11865211419251BindingDB-show
CHEMBL11887011289167BindingDB-show
CHEMBL11908611202498BindingDB-show
CHEMBL11918811383848BindingDB-show
CHEMBL11918911278942BindingDB-show
CHEMBL11922411231647BindingDB-show
CHEMBL11956811256615BindingDB-show
CHEMBL11966911738598BindingDB-show
CHEMBL1201239998014BindingDB-show
CHEMBL1363612996853BindingDB-show
CHEMBL15805411185091BindingDB-show
CHEMBL15857011154519BindingDB-show
CHEMBL15863911208245BindingDB-show
CHEMBL15869111818325BindingDB-show
CHEMBL15903211257841BindingDB-show
CHEMBL15904011288025BindingDB-show
CHEMBL15905211180416BindingDB-show
CHEMBL16100911450092BindingDB-show
CHEMBL16103411303895BindingDB-show
CHEMBL16111710271795BindingDB-show
CHEMBL16145111486149BindingDB-show
CHEMBL16167310245546BindingDB-show
CHEMBL16175711351662BindingDB-show
CHEMBL16212611152240BindingDB-show
CHEMBL2139511046337BindingDB-show
CHEMBL2140710266000BindingDB-show
CHEMBL2141423423601BindingDB-show
CHEMBL2149410018953BindingDB-show
CHEMBL2169111121319BindingDB-show
CHEMBL2177811020649BindingDB-show
CHEMBL2188510945514BindingDB-show
CHEMBL219219974420BindingDB-show
CHEMBL2203913926968BindingDB-show
CHEMBL2212911015286BindingDB-show
CHEMBL2213711048457BindingDB-show
CHEMBL2213811047913BindingDB-show
CHEMBL2213910434110BindingDB-show
CHEMBL2227110905790BindingDB-show
CHEMBL2235710902094BindingDB-show
CHEMBL2240310927461BindingDB-show
CHEMBL2240510426185BindingDB-show
CHEMBL226939814965BindingDB-show
CHEMBL2281111026309BindingDB-show
CHEMBL2290110365962BindingDB-show
CHEMBL2511211091680BindingDB-show
CHEMBL27403110828475BindingDB-show
CHEMBL27881310090457BindingDB-show
CHEMBL27884710060600BindingDB-show
CHEMBL27950910937436BindingDB-show
CHEMBL27994811026315BindingDB-show
CHEMBL27998611119819BindingDB-show
CHEMBL28041011081653BindingDB-show
CHEMBL29193111450525BindingDB-show
CHEMBL2977310466996BindingDB-show
CHEMBL3093710335810BindingDB-show
CHEMBL32477511175353BindingDB-show
CHEMBL3255339972300BindingDB-show
CHEMBL33377911234309BindingDB-show
CHEMBL34514610914065BindingDB-show
CHEMBL34693211463215BindingDB-show
CHEMBL34696311255710BindingDB-show
CHEMBL34698211428294BindingDB-show
CHEMBL34719011369668BindingDB-show
CHEMBL34815111282588BindingDB-show
CHEMBL35109911188944BindingDB-show
CHEMBL35219511224057BindingDB-show
CHEMBL35244110476801BindingDB-show
CHEMBL35401111750096BindingDB-show
CHEMBL41637311091885BindingDB-show
CHEMBL41637611732019BindingDB-show
CHEMBL4165529881905BindingDB-show
CHEMBL41905510245325BindingDB-show
CHEMBL41923111289209BindingDB-show
CHEMBL42200511369471BindingDB-show
CHEMBL43477110634938BindingDB-show
CHEMBL44460511290186BindingDB-show
CHEMBL900189877881BindingDB-show
CHEMBL9284644325327BindingDB-show
CHEMBL9300144325367BindingDB-show
CHEMBL944709679790BindingDB-show
CHEMBL952749583359BindingDB-show
chlorcycloguanil9049BindingDB-show
Diaminopyritamin4993BindingDB-show
Diaminopyritamin4993DrugBank-show
Diaminopyritamin4993SuperTarget-show
DIAVERIDINE21453BindingDB-show
Ethodichlorophen29142BindingDB-show
Iem 68772565BindingDB-show
MLS0003275152764922BindingDB-show
NSC 2675711036BindingDB-show
NSC211275427350BindingDB-show
NSC211939427454BindingDB-show
NSC2742795358721BindingDB-show
NSC3077 (HYDROCHLORIDE SALT)25889BindingDB-show
p1813926986BindingDB-show
Proguanil4923DrugBank-show
Proguanil4923SuperTargetPMID 1356539show
SMR0001805161473299BindingDB-show
Sulfamethoprim5578BindingDB-show
TCMDC-138984134531BindingDB-show
Trp-P-25284476BindingDB-show
X 48407233BindingDB-show
ZINC001280652747162BindingDB-show
ZINC00146421732267BindingDB-show
ZINC043446369584159BindingDB-show
ZINC047101939581136BindingDB-show
Synonyms:
Bifunctional dihydrofolate reductase-thymidylate synthase
DHFR-TS
Similar targets:
Uniprot name% Sequence similarity% Sequence identity
DRTS_PLABA81.170.6
Q27552_CRYPV53.737.6
Q53Y97_HUMAN3526.6
TYSY_RAT3527
TYSY_HUMAN3526.6
Q53FB7_HUMAN3526.5
TYSY_PNECA34.927.4
CP2F1_HUMAN31.617.1
CAN1_RAT31.517.9
TYSY_CANAL31.524.6
PGH2_MOUSE3115.2
Q8WYK3_HUMAN30.823.8
TGM3_HUMAN30.515.4
PGH2_SHEEP30.414.2
PGH2_BOVIN30.314.5
PGH2_RAT30.315.2
AMYS_NEIPO30.117
NTP1_MCV13016.4
GYRB_STAAC3017.5
B5RQL8_BORRA29.914.5
ILV5_SPIOL29.817
HEP2_HUMAN29.715.2
LGSN_HUMAN29.716.2
B8M0Z5_TALSN29.617.3
Q53688_9CREN29.514.6
Q8VVD2_GEOSE29.515.4
FRD2_SHEFN29.416.7
TYSY_ECOLI29.421.1
DLD_ECOLI29.217.2
SGPL1_HUMAN29.116.2
Protein-Protein Interactions:
No data available