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Target Details

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Name:Estradiol 17-beta-dehydrogenase 1
Uniprot name:DHB1_HUMAN
Accession Numbers:B3KXS1 P14061 Q2M2L8
EC-Number:1.1.1.62
Organism:Homo sapiens
Human
PDB IDs:1A27 1BHS 1DHT 1EQU 1FDS 1FDT 1FDU 1FDV 1FDW 1I5R 1IOL 1JTV 1QYV 1QYW 1QYX 3DHE
KEGG Pathways:-
Drugs:
NamePubChem IDSourceReferencesInteraction
2-METHOXYESTRONE440624BindingDB-show
7-Hydroxyflavone5281894BindingDB-show
AC1OCFOX6918651BindingDB-show
Acetylglycyrrhetinic acid94320BindingDB-show
AF-399/421771682950639BindingDB-show
AK-968/403897056874186BindingDB-show
Androstanedione222865DrugBank-show
Androstenedione6128DrugBank-show
Apigenine5280443BindingDB-show
BVT-142256918663BindingDB-show
CHEBI:1216855702052BindingDB-show
CHEMBL107630611493379BindingDB-show
CHEMBL108010711639661BindingDB-show
CHEMBL108030711551133BindingDB-show
CHEMBL108063311690058BindingDB-show
CHEMBL108063411609517BindingDB-show
CHEMBL108117246879677BindingDB-show
CHEMBL108136111587774BindingDB-show
CHEMBL108136211631931BindingDB-show
CHEMBL108172311196876BindingDB-show
CHEMBL109602646887579BindingDB-show
CHEMBL109602746887580BindingDB-show
CHEMBL109637546887581BindingDB-show
CHEMBL109701446844318BindingDB-show
CHEMBL109701646887555BindingDB-show
CHEMBL109741746887511BindingDB-show
CHEMBL109931246887551BindingDB-show
CHEMBL127562649840130BindingDB-show
CHEMBL127724949840059BindingDB-show
CHEMBL127725049840060BindingDB-show
CHEMBL127733949840061BindingDB-show
CHEMBL127734049840062BindingDB-show
CHEMBL127734149840063BindingDB-show
CHEMBL127742949840065BindingDB-show
CHEMBL127752249840129BindingDB-show
CHEMBL127752349840201BindingDB-show
CHEMBL127761549840131BindingDB-show
CHEMBL127761649840132BindingDB-show
CHEMBL127761749840133BindingDB-show
CHEMBL127770849840134BindingDB-show
CHEMBL127770949840135BindingDB-show
CHEMBL127771049840195BindingDB-show
CHEMBL127780149840196BindingDB-show
CHEMBL127780249840197BindingDB-show
CHEMBL127780349840198BindingDB-show
CHEMBL127788449840200BindingDB-show
CHEMBL127788552945269BindingDB-show
CHEMBL18967744399786BindingDB-show
CHEMBL19288444400068BindingDB-show
CHEMBL19426144403775BindingDB-show
CHEMBL19457944403851BindingDB-show
CHEMBL19469044403837BindingDB-show
CHEMBL19521710192730BindingDB-show
CHEMBL19670944403787BindingDB-show
CHEMBL19705644403805BindingDB-show
CHEMBL19822344403843BindingDB-show
CHEMBL19855811721794BindingDB-show
CHEMBL19861344403846BindingDB-show
CHEMBL20128444407490BindingDB-show
CHEMBL20146444407573BindingDB-show
CHEMBL20160544407373BindingDB-show
CHEMBL20184144407474BindingDB-show
CHEMBL20199144407376BindingDB-show
CHEMBL20207844407683BindingDB-show
CHEMBL20221344407402BindingDB-show
CHEMBL20250344407510BindingDB-show
CHEMBL20690844412042BindingDB-show
CHEMBL25701011710272BindingDB-show
CHEMBL30762144314270BindingDB-show
CHEMBL30843144307459BindingDB-show
CHEMBL33275611599989BindingDB-show
CHEMBL36406044403833BindingDB-show
CHEMBL36575244403850BindingDB-show
CHEMBL36958811621606BindingDB-show
CHEMBL36989744403770BindingDB-show
CHEMBL37057011813984BindingDB-show
CHEMBL37057111700170BindingDB-show
CHEMBL37253544407466BindingDB-show
CHEMBL37254044403816BindingDB-show
CHEMBL37256011571162BindingDB-show
CHEMBL37325711526147BindingDB-show
CHEMBL37338344422488BindingDB-show
CHEMBL38067711319723BindingDB-show
CHEMBL38140044407797BindingDB-show
CHEMBL38146644403818BindingDB-show
CHEMBL38211444405125BindingDB-show
CHEMBL43495044403826BindingDB-show
CHEMBL43862444403836BindingDB-show
CHEMBL45018921861202BindingDB-show
CHEMBL45025625093399BindingDB-show
CHEMBL45637925093374BindingDB-show
CHEMBL45638025093375BindingDB-show
CHEMBL45638225093376BindingDB-show
CHEMBL45701325093378BindingDB-show
CHEMBL45732325093386BindingDB-show
CHEMBL45743516721115BindingDB-show
CHEMBL45743825093384BindingDB-show
CHEMBL45757425093371BindingDB-show
CHEMBL45872725093373BindingDB-show
CHEMBL45997625093397BindingDB-show
CHEMBL46018225093398BindingDB-show
CHEMBL46102725093392BindingDB-show
CHEMBL46167525093395BindingDB-show
CHEMBL46167625093396BindingDB-show
CHEMBL46251125093388BindingDB-show
CHEMBL46251325093389BindingDB-show
CHEMBL46715124950391BindingDB-show
CHEMBL46922724894072BindingDB-show
CHEMBL46990944561552BindingDB-show
CHEMBL4723349651871BindingDB-show
CHEMBL48875144585931BindingDB-show
CHEMBL48875224857878BindingDB-show
CHEMBL49979644585930BindingDB-show
CHEMBL50290821257907BindingDB-show
CHEMBL50339925093379BindingDB-show
CHEMBL50516122554906BindingDB-show
CHEMBL50552325093391BindingDB-show
CHEMBL51153025093387BindingDB-show
CHEMBL51219625093377BindingDB-show
CHEMBL52944625192184BindingDB-show
CHEMBL56652144542795BindingDB-show
CHEMBL56893944542651BindingDB-show
CHEMBL56894445484071BindingDB-show
CHEMBL56894544543257BindingDB-show
CHEMBL56986225192621BindingDB-show
CHEMBL56988544542047BindingDB-show
CHEMBL57010244543260BindingDB-show
CHEMBL57011044543255BindingDB-show
CHEMBL57011744542195BindingDB-show
CHEMBL57036825192620BindingDB-show
CHEMBL57059544542049BindingDB-show
CHEMBL57059625192475BindingDB-show
CHEMBL57105444542947BindingDB-show
CHEMBL57126244542045BindingDB-show
CHEMBL57194125192481BindingDB-show
CHEMBL57216444543104BindingDB-show
CHEMBL57216544543105BindingDB-show
CHEMBL57217144543261BindingDB-show
CHEMBL57277744542948BindingDB-show
CHEMBL57300325192476BindingDB-show
CHEMBL57345844542652BindingDB-show
CHEMBL57369144542194BindingDB-show
CHEMBL57631825192480BindingDB-show
CHEMBL57649544542044BindingDB-show
CHEMBL57668244542800BindingDB-show
CHEMBL57689644543108BindingDB-show
CHEMBL57732725192479BindingDB-show
CHEMBL57733825192477BindingDB-show
CHEMBL57792525192478BindingDB-show
CHEMBL58351925192619BindingDB-show
CHEMBL58352044542048BindingDB-show
CHEMBL58373444542193BindingDB-show
CHEMBL58393044542650BindingDB-show
CHEMBL58414325192622BindingDB-show
CHEMBL58573344542799BindingDB-show
CHEMBL6709744307446BindingDB-show
CHEMBL6755944307443BindingDB-show
CHEMBL6904544308188BindingDB-show
CHEMBL6912744308203BindingDB-show
CHEMBL7589344314513BindingDB-show
CID 1133980511339805BindingDB-show
CID 1150062011709431BindingDB-show
CID 1151524311573293BindingDB-show
CID 1152045811520458BindingDB-show
CID 1152045811721764BindingDB-show
CID 1153037711530377BindingDB-show
CID 1156585611565856BindingDB-show
CID 1159453311500319BindingDB-show
CID 1161699011616990BindingDB-show
CID 1161699011717031BindingDB-show
CID 1163928911639289BindingDB-show
CID 1165980411716781BindingDB-show
CID 1165980411515312BindingDB-show
CID 1166791911682274BindingDB-show
CID 1167478611617341BindingDB-show
CID 410511711853305BindingDB-show
CID 983609911493223BindingDB-show
CID 98793249879324BindingDB-show
CID 995382311293006BindingDB-show
CID 996646711098954BindingDB-show
Compound 5443630776BindingDB-show
Dehydroepiandrosterone5881DrugBank-show
Dehydroepiandrosterone5881SuperTarget-show
dihydrodiphosphopyridine nucleotide439153DrugBank-show
Dihydroequilenin223368DrugBank-show
Dihydrofolliculin5757SuperTarget-show
Dihydrotestosterone10635DrugBank-show
Dihydrotestosterone10635SuperTarget-show
E2-adenosine hybrid compound, 723647684BindingDB-show
E2-adenosine hybrid compound, 923647686BindingDB-show
E9642_SIGMA6710658BindingDB-show
EM-174523647685BindingDB-show
EM-1745446201BindingDB-show
EM-1745446201DrugBank-show
endosulfan3224BindingDB-show
Genisterin5280961BindingDB-show
hydroxyphenyl substituted benzene, 34667696BindingDB-show
Ketohydroxyoestrin5870BindingDB-show
MB-329-131A223647687BindingDB-show
NAD449328DrugBank-show
naringenin932BindingDB-show
NSC111295269792BindingDB-show
NSC250430317611BindingDB-show
Pelargidenolon5280863BindingDB-show
Trihydroxypropane753SuperTarget-show
Triphosphopyridine nucleotide5886DrugBank-show
Triphosphopyridine nucleotide5885DrugBank-show
Synonyms:
17-beta-HSD 1
17-beta-hydroxysteroid dehydrogenase type 1
20 alpha-hydroxysteroid dehydrogenase
20-alpha-HSD
E2DH
Estradiol 17-beta-dehydrogenase 1
Placental 17-beta-hydroxysteroid dehydrogenase
Similar targets:
Uniprot name% Sequence similarity% Sequence identity
RDH8_HUMAN51.139.1
DHG_BACME37.122.3
LVR_LEIAQ36.924.4
BUDC_KLEPN35.823.8
CATS_HUMAN35.319.1
GALE_HUMAN34.722.6
H17B6_HUMAN34.521.9
Q19774_CAEEL34.321.2
DHB11_HUMAN34.322.5
PSBP3_TOBAC34.220.9
DCXR_HUMAN34.219.6
PGDH_HUMAN34.220.7
DHB8_HUMAN34.121.3
Q9X0Q1_THEMA34.119
PER1_ARAHY3418.4
RDH1_HUMAN33.923.2
HSD_STREX33.821.5
Q9WYS2_THEMA33.720.7
ACT3_STRCO3323.4
TRPA_MAIZE32.818.1
DHRS4_HUMAN32.719.8
GLO2N_ARATH32.418.8
BDH_HUMAN32.321.7
Q888A4_PSESM32.219.3
O75100_HUMAN32.218.7
TRN1_DATST32.218.8
CBR1_HUMAN32.221.8
DHI1_RAT32.119.9
DHI2_HUMAN3221.4
UCRI_BOVIN3221.3
Protein-Protein Interactions: