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Target Details

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Name:DAP kinase 1
Uniprot name:DAPK1_HUMAN
Accession Numbers:P53355 Q14CQ7 Q68CP8 Q9BTL8
EC-Number:2.7.11.1
Organism:Homo sapiens
Human
PDB IDs:1IG1 1JKK 1JKL 1JKS 1JKT 1P4F 1WVW 1WVX 1WVY 1YR5 3DFC 3DGK 3EH9 3EHA 3F5G 3F5U
KEGG Pathways:show KEGG Pathways
Drugs:
NamePubChem IDSourceReferencesInteraction
3-((3R,4R)-4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperi9926791BindingDB-show
5,6-dihydrobenzo[h]cinnolin-3-amine5288116DrugBank-show
ABT-86911485656BindingDB-show
ADENYLYL IMIDODIPHOSPHATE33113DrugBank-show
AMG 70611667893BindingDB-show
AST-48711409972BindingDB-show
Bio2_0004136610353BindingDB-show
Canertinib156414BindingDB-show
CHEBI:1043465459219BindingDB-show
CHEBI:25992444329707BindingDB-show
CHEBI:66834345481533BindingDB-show
CHEBI:66834445481534BindingDB-show
CHEMBL11553110369873BindingDB-show
CHEMBL11696324955953BindingDB-show
CHEMBL11744344343747BindingDB-show
CHEMBL124070352945601BindingDB-show
CHEMBL128858249839480BindingDB-show
CHIR-26511656518BindingDB-show
CP-7247149874913BindingDB-show
Dasatinib3062316BindingDB-show
Doramapimod156422BindingDB-show
Erlotinib176870BindingDB-show
Gefitinib123631BindingDB-show
GW-258011617559BindingDB-show
Imatinib Methansulfonate5291BindingDB-show
Lapatinib ditosylate208908BindingDB-show
Lestaurtinib126565BindingDB-show
Minaprine dihydrochloride4199BindingDB-show
MLN805411712649BindingDB-show
Pazopanib10113978BindingDB-show
PI-1039884685BindingDB-show
PKC-4129829523BindingDB-show
Roscovitine160355BindingDB-show
Ruboxistaurin153999BindingDB-show
RWJ-3872525330790BindingDB-show
S1018_Selleck9977819BindingDB-show
S1147_Selleck16007391BindingDB-show
S1526_Selleck24889392BindingDB-show
SB 2021905353940BindingDB-show
SB-4315424521392BindingDB-show
SNS-0323025986BindingDB-show
sorafenibum216239BindingDB-show
staurosporine44299148BindingDB-show
SU-1481310138259BindingDB-show
Sunitinib5329102BindingDB-show
Tandutinib3038522BindingDB-show
Vandetanib3081361BindingDB-show
Vatalanib151194BindingDB-show
VX-6805494449BindingDB-show
VX-7453038525BindingDB-show
Synonyms:
DAP kinase 1
Death-associated protein kinase 1
Similar targets:
Uniprot name% Sequence similarity% Sequence identity
SLK_CAVPO31.719.5
ROCK1_HUMAN30.515.6
NOS2_CHICK29.517.1
AT12A_HUMAN29.316.2
POL_SIVM129.215.8
RDRP_REOVD28.416.5
APAF_HUMAN28.216.7
RPOC_MYCTU27.916.2
TOP2A_RAT27.815.3
KIF1A_HUMAN27.516.1
POLS_EEVVT27.216.2
SYIC_HUMAN27.216.4
ABCC8_HUMAN27.215.5
KDM5D_HUMAN27.116.5
CSKP_HUMAN2714.7
POL_FIVPE2714.8
METH_HUMAN26.715.8
DPOLA_HUMAN26.615.1
TOP2A_HUMAN26.514.9
SUIS_HUMAN26.214.7
TAOK2_RAT26.114.9
O32393_SPIPL26.115.9
AT2A2_HUMAN25.914.4
GCSP_HUMAN25.814.3
NPCL1_HUMAN25.714.5
POL_HV2RO25.515.2
AT2A2_MOUSE25.413.9
ITAL_HUMAN25.314.7
NOS1_HUMAN25.115
RPOB_ECOLI25.115.2
Protein-Protein Interactions: