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Target Details

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Name:Tyrosine-protein kinase CSK
Uniprot name:CSK_HUMAN
Accession Numbers:P41240 Q2M3N2 Q6FGZ6
EC-Number:2.7.10.2
Organism:Homo sapiens
Human
PDB IDs:1BYG 1CSK 3D7T 3D7U
KEGG Pathways:show KEGG Pathways
Drugs:
NamePubChem IDSourceReferencesInteraction
2,4-dianilino pyrimidine, 225138012BindingDB-show
3-((3R,4R)-4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperi9926791BindingDB-show
7-Cyclopentyl-5-(4-phenoxy)phenyl-7H-pyrrolo[2,3-d]pyrimidin-4-ylamine6603792BindingDB-show
ABT-86911485656BindingDB-show
AMG 70611667893BindingDB-show
AST-48711409972BindingDB-show
Bosutinib5328940BindingDB-show
Canertinib156414BindingDB-show
CHEBI:1043465459219BindingDB-show
CHEBI:25992444329707BindingDB-show
CHEBI:523095154691BindingDB-show
CHEBI:66834345481533BindingDB-show
CHEBI:66834445481534BindingDB-show
CHEMBL10543644335197BindingDB-show
CHEMBL1122639927800BindingDB-show
CHEMBL11234620579089BindingDB-show
CHEMBL11318515550318BindingDB-show
CHEMBL124070352945601BindingDB-show
CHEMBL17297315858662BindingDB-show
CHEMBL17345344384965BindingDB-show
CHEMBL17347844384547BindingDB-show
CHEMBL17540910432113BindingDB-show
CHEMBL17670210451087BindingDB-show
CHEMBL2013079916282BindingDB-show
CHEMBL21580316046126BindingDB-show
CHEMBL21859316094828BindingDB-show
CHEMBL21876744418760BindingDB-show
CHEMBL21876816094818BindingDB-show
CHEMBL21876916094834BindingDB-show
CHEMBL21911714147704BindingDB-show
CHEMBL21919916094816BindingDB-show
CHEMBL21944916094819BindingDB-show
CHEMBL21947316094817BindingDB-show
CHEMBL21950016094837BindingDB-show
CHEMBL21955216094835BindingDB-show
CHEMBL21991716094815BindingDB-show
CHEMBL22004416094838BindingDB-show
CHEMBL22007016094836BindingDB-show
CHEMBL22012916094824BindingDB-show
CHEMBL22018116094827BindingDB-show
CHEMBL22019316094832BindingDB-show
CHEMBL3220669888491BindingDB-show
CHEMBL37342216094821BindingDB-show
CHEMBL37382516094830BindingDB-show
CHEMBL37471916094822BindingDB-show
CHEMBL37619716094823BindingDB-show
CHEMBL37672716094839BindingDB-show
CHEMBL38578216094820BindingDB-show
CHEMBL42437544384964BindingDB-show
CHEMBL42597716094829BindingDB-show
CHEMBL43613711719421BindingDB-show
CHEMBL45542811675054BindingDB-show
CHEMBL47581711626920BindingDB-show
CHEMBL55514916094831BindingDB-show
CHEMBL58963046224908BindingDB-show
CHEMBL59132546225169BindingDB-show
CHIR-26511656518BindingDB-show
CID 99267919818231BindingDB-show
CP-7247149874913BindingDB-show
Dasatinib3062316BindingDB-show
Doramapimod156422BindingDB-show
Erlotinib176870BindingDB-show
Gefitinib123631BindingDB-show
GW-258011617559BindingDB-show
Imatinib Methansulfonate5291BindingDB-show
JAK Inhibitor I5494425BindingDB-show
Krisolamine31420BindingDB-show
L-Tyrosine hydrazide72779BindingDB-show
Lapatinib ditosylate208908BindingDB-show
Lestaurtinib126565BindingDB-show
MLN805411712649BindingDB-show
n-hydroxy-l-tyrosinamide256524BindingDB-show
nchembio.117-comp91400BindingDB-show
NSC606429354471BindingDB-show
Pazopanib10113978BindingDB-show
Pelitinib6445562BindingDB-show
PI-1039884685BindingDB-show
PKC-41224202429BindingDB-show
PKC-4129829523BindingDB-show
pp1 analog4877BindingDB-show
Pyrrolo[2,3-d]pyrimidine 16539952BindingDB-show
Roscovitine160355BindingDB-show
Ruboxistaurin153999BindingDB-show
RWJ-3872525330790BindingDB-show
S1018_Selleck9977819BindingDB-show
S1147_Selleck16007391BindingDB-show
S1152_Selleck24180719BindingDB-show
S1526_Selleck24889392BindingDB-show
Saracatinib10302451BindingDB-show
SB 2021905353940BindingDB-show
SB-4315424521392BindingDB-show
SNS-0323025986BindingDB-show
sorafenibum216239BindingDB-show
STAUROSPORINE44259BindingDB-show
staurosporine451705BindingDB-show
staurosporine44299148BindingDB-show
STAUROSPORINE44259DrugBank-show
SU-1481310138259BindingDB-show
Sunitinib5329102BindingDB-show
Tandutinib3038522BindingDB-show
Vandetanib3081361BindingDB-show
Vatalanib151194BindingDB-show
VX-6805494449BindingDB-show
VX-7453038525BindingDB-show
Synonyms:
C-SRC kinase
Protein-tyrosine kinase CYL
Tyrosine-protein kinase CSK
Similar targets:
Uniprot name% Sequence similarity% Sequence identity
LCK_HUMAN49.934.3
FYN_HUMAN48.131.7
YES_HUMAN47.931.6
SRC_RSVSE47.334.4
SRC_HUMAN47.333.6
HCK_HUMAN47.231.8
SRC_RAT46.833.6
TGFR1_RAT40.221.9
ITK_HUMAN40.125.8
KSYK_HUMAN38.327.9
BTK_HUMAN38.125.5
ZAP70_HUMAN3725.7
ILK_CAVPO36.921.4
ACV1B_HUMAN36.820.5
ACVR1_HUMAN36.321.1
CP19A_HUMAN33.717.8
STK6_HUMAN33.618.3
ARAF_HUMAN33.120
KPEL_DROME32.819.8
SPSY_MOUSE32.517.4
PYRD_RAT32.419.8
CBPA6_MOUSE32.318.3
PGES2_HUMAN32.218.8
MP2K4_HUMAN32.120
Q46220_CLOPE32.116.7
Q9Y6B5_HUMAN32.119.3
CP119_SULAC3216.7
ECI2_HUMAN31.917.9
PURA_WHEAT31.817.2
PGKC_TRYBB31.818
Protein-Protein Interactions: