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Target Details

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Name:Macrophage colony-stimulating factor 1 receptor
Uniprot name:CSF1R_HUMAN
Accession Numbers:P07333 Q6LDW5 Q6LDY4
EC-Number:2.7.10.1
Organism:Homo sapiens
Human
PDB IDs:2I0V 2I0Y 2I1M 2OGV 3BEA 3DPK
KEGG Pathways:show KEGG Pathways
Drugs:
NamePubChem IDSourceReferencesInteraction
3-((3R,4R)-4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperi9926791BindingDB-show
4-Anilino quinazoline deriv. 115328016BindingDB-show
4-Anilinoquinazoline 225329048BindingDB-show
4434904144349041BindingDB-show
5CN9884318BindingDB-show
ABT-86911485656BindingDB-show
AMG 70611667893BindingDB-show
Aminobenzoisoxazole, 4911429654BindingDB-show
Aminobenzoisoxazole, 5011374110BindingDB-show
Aminobenzoisoxazole, 5111429729BindingDB-show
anthranyl amide derivative C6398883BindingDB-show
arylamide, 811654378BindingDB-show
AST-48711409972BindingDB-show
Canertinib156414BindingDB-show
CHEBI:1043465459219BindingDB-show
CHEBI:25992444329707BindingDB-show
CHEBI:54743644560358BindingDB-show
CHEBI:66834345481533BindingDB-show
CHEBI:66834445481534BindingDB-show
CHEMBL1023019890746BindingDB-show
CHEMBL10696610905857BindingDB-show
CHEMBL107673546880882BindingDB-show
CHEMBL107954511200284BindingDB-show
CHEMBL108150911189588BindingDB-show
CHEMBL108727946880930BindingDB-show
CHEMBL108728046880931BindingDB-show
CHEMBL108766146880884BindingDB-show
CHEMBL108766246870016BindingDB-show
CHEMBL108804046880881BindingDB-show
CHEMBL108817546880883BindingDB-show
CHEMBL108859846880842BindingDB-show
CHEMBL108859946880843BindingDB-show
CHEMBL116997924783104BindingDB-show
CHEMBL116998049798632BindingDB-show
CHEMBL117078425104233BindingDB-show
CHEMBL117078524783100BindingDB-show
CHEMBL117078624783102BindingDB-show
CHEMBL117099749798631BindingDB-show
CHEMBL117138524783358BindingDB-show
CHEMBL117160424783357BindingDB-show
CHEMBL117160524783356BindingDB-show
CHEMBL117160624783618BindingDB-show
CHEMBL117160716755734BindingDB-show
CHEMBL117177624759614BindingDB-show
CHEMBL117177724785380BindingDB-show
CHEMBL117211624758277BindingDB-show
CHEMBL117211724759173BindingDB-show
CHEMBL117231324759170BindingDB-show
CHEMBL117231424758022BindingDB-show
CHEMBL117234524758275BindingDB-show
CHEMBL117234624759171BindingDB-show
CHEMBL117234724758276BindingDB-show
CHEMBL117252849798465BindingDB-show
CHEMBL117252924758021BindingDB-show
CHEMBL117253024759510BindingDB-show
CHEMBL121521846847552BindingDB-show
CHEMBL12403510117540BindingDB-show
CHEMBL124070352945601BindingDB-show
CHEMBL124297746929544BindingDB-show
CHEMBL12589810231458BindingDB-show
CHEMBL128816049839481BindingDB-show
CHEMBL13314744355892BindingDB-show
CHEMBL13443918770822BindingDB-show
CHEMBL13541722692676BindingDB-show
CHEMBL13592844355543BindingDB-show
CHEMBL13601144355673BindingDB-show
CHEMBL1758629951708BindingDB-show
CHEMBL17601910318355BindingDB-show
CHEMBL17607810452258BindingDB-show
CHEMBL17729810249989BindingDB-show
CHEMBL22397111590078BindingDB-show
CHEMBL23757024180608BindingDB-show
CHEMBL24537716747696BindingDB-show
CHEMBL24576944440254BindingDB-show
CHEMBL24596844440256BindingDB-show
CHEMBL24616644440259BindingDB-show
CHEMBL24874044444469BindingDB-show
CHEMBL24893044444467BindingDB-show
CHEMBL24893144444538BindingDB-show
CHEMBL24893344444470BindingDB-show
CHEMBL24895844444491BindingDB-show
CHEMBL24895944444494BindingDB-show
CHEMBL24912411336497BindingDB-show
CHEMBL24913744444543BindingDB-show
CHEMBL24913844444544BindingDB-show
CHEMBL24913944444545BindingDB-show
CHEMBL24916244444496BindingDB-show
CHEMBL24916344444498BindingDB-show
CHEMBL24916944444451BindingDB-show
CHEMBL24917044444453BindingDB-show
CHEMBL24933011484747BindingDB-show
CHEMBL24934611232263BindingDB-show
CHEMBL24937144444501BindingDB-show
CHEMBL24937744444456BindingDB-show
CHEMBL24954244444587BindingDB-show
CHEMBL24954311231718BindingDB-show
CHEMBL24954444444472BindingDB-show
CHEMBL24954544444473BindingDB-show
CHEMBL24957344444458BindingDB-show
CHEMBL24957444444459BindingDB-show
CHEMBL24974744444589BindingDB-show
CHEMBL24974844444590BindingDB-show
CHEMBL24974944444591BindingDB-show
CHEMBL24975144444476BindingDB-show
CHEMBL24975244444477BindingDB-show
CHEMBL24977944444461BindingDB-show
CHEMBL24978144444464BindingDB-show
CHEMBL24995544444592BindingDB-show
CHEMBL24995644444593BindingDB-show
CHEMBL24995728408236BindingDB-show
CHEMBL24996044444546BindingDB-show
CHEMBL25015611395681BindingDB-show
CHEMBL25015711327103BindingDB-show
CHEMBL25016044444547BindingDB-show
CHEMBL25016144444548BindingDB-show
CHEMBL25018744444514BindingDB-show
CHEMBL25018844444515BindingDB-show
CHEMBL25036244444549BindingDB-show
CHEMBL25036444444551BindingDB-show
CHEMBL25057125021199BindingDB-show
CHEMBL25057244444552BindingDB-show
CHEMBL25077411328012BindingDB-show
CHEMBL25077544444555BindingDB-show
CHEMBL25095844444584BindingDB-show
CHEMBL25095944444585BindingDB-show
CHEMBL25115711301179BindingDB-show
CHEMBL25117344444479BindingDB-show
CHEMBL25117444444480BindingDB-show
CHEMBL25135144444533BindingDB-show
CHEMBL25136744444481BindingDB-show
CHEMBL25157544444484BindingDB-show
CHEMBL25158644444489BindingDB-show
CHEMBL25184211704205BindingDB-show
CHEMBL25243611690004BindingDB-show
CHEMBL25263344447263BindingDB-show
CHEMBL25263444447265BindingDB-show
CHEMBL25282211654827BindingDB-show
CHEMBL25283211502118BindingDB-show
CHEMBL25283411682945BindingDB-show
CHEMBL25302611545281BindingDB-show
CHEMBL25302711574080BindingDB-show
CHEMBL25386411277266BindingDB-show
CHEMBL25388411695784BindingDB-show
CHEMBL25449611710948BindingDB-show
CHEMBL25449811698112BindingDB-show
CHEMBL25490811606951BindingDB-show
CHEMBL25490911611808BindingDB-show
CHEMBL25491011619776BindingDB-show
CHEMBL31989411729539BindingDB-show
CHEMBL32333610457505BindingDB-show
CHEMBL34753744368815BindingDB-show
CHEMBL35550510271801BindingDB-show
CHEMBL38974544427519BindingDB-show
CHEMBL39015616220354BindingDB-show
CHEMBL39542744440261BindingDB-show
CHEMBL39823711685397BindingDB-show
CHEMBL39823844447253BindingDB-show
CHEMBL39836044444594BindingDB-show
CHEMBL39846944444550BindingDB-show
CHEMBL39850844447259BindingDB-show
CHEMBL39850911502871BindingDB-show
CHEMBL39873444444588BindingDB-show
CHEMBL39892044444455BindingDB-show
CHEMBL39893311220125BindingDB-show
CHEMBL39911725163930BindingDB-show
CHEMBL39911844444463BindingDB-show
CHEMBL39913044444579BindingDB-show
CHEMBL39934311460725BindingDB-show
CHEMBL39944144444486BindingDB-show
CHEMBL39954144444535BindingDB-show
CHEMBL39954211186408BindingDB-show
CHEMBL39954311209405BindingDB-show
CHEMBL39964744444503BindingDB-show
CHEMBL39970244444553BindingDB-show
CHEMBL39973944444466BindingDB-show
CHEMBL39976311689712BindingDB-show
CHEMBL39993244444471BindingDB-show
CHEMBL39995744444522BindingDB-show
CHEMBL40012344444586BindingDB-show
CHEMBL40025911625534BindingDB-show
CHEMBL40028844444474BindingDB-show
CHEMBL40028944444475BindingDB-show
CHEMBL40075311280046BindingDB-show
CHEMBL40093944444583BindingDB-show
CHEMBL40119844444518BindingDB-show
CHEMBL40142044444482BindingDB-show
CHEMBL42822844444541BindingDB-show
CHEMBL42894511567250BindingDB-show
CHEMBL42983711232236BindingDB-show
CHEMBL43923311232741BindingDB-show
CHEMBL4425919945927BindingDB-show
CHEMBL44358744444539BindingDB-show
CHEMBL4440649828962BindingDB-show
CHEMBL44467123629682BindingDB-show
CHEMBL45020822170247BindingDB-show
CHEMBL45266444571145BindingDB-show
CHEMBL45305744560803BindingDB-show
CHEMBL45410411574855BindingDB-show
CHEMBL45410544561837BindingDB-show
CHEMBL45461644561800BindingDB-show
CHEMBL45487644561838BindingDB-show
CHEMBL4563759882621BindingDB-show
CHEMBL45947044561916BindingDB-show
CHEMBL45947144561917BindingDB-show
CHEMBL45967444561918BindingDB-show
CHEMBL45967523630162BindingDB-show
CHEMBL46136544561919BindingDB-show
CHEMBL46136644561920BindingDB-show
CHEMBL46157223630121BindingDB-show
CHEMBL46157323630122BindingDB-show
CHEMBL46157423630124BindingDB-show
CHEMBL46195011682482BindingDB-show
CHEMBL46195144561876BindingDB-show
CHEMBL46195244561877BindingDB-show
CHEMBL46212823630126BindingDB-show
CHEMBL46213023630167BindingDB-show
CHEMBL46213223630127BindingDB-show
CHEMBL46213323630125BindingDB-show
CHEMBL46988344593407BindingDB-show
CHEMBL47234244562059BindingDB-show
CHEMBL47234344562060BindingDB-show
CHEMBL47251244562061BindingDB-show
CHEMBL47581711626920BindingDB-show
CHEMBL47864924856363BindingDB-show
CHEMBL47926744571015BindingDB-show
CHEMBL47944544571221BindingDB-show
CHEMBL47944644571223BindingDB-show
CHEMBL47944744571224BindingDB-show
CHEMBL47963622170203BindingDB-show
CHEMBL47984522170305BindingDB-show
CHEMBL47984644570928BindingDB-show
CHEMBL47984722170354BindingDB-show
CHEMBL48005622170297BindingDB-show
CHEMBL48005744570804BindingDB-show
CHEMBL48005810132097BindingDB-show
CHEMBL48025044571021BindingDB-show
CHEMBL48041744570850BindingDB-show
CHEMBL48044544571022BindingDB-show
CHEMBL48045544571101BindingDB-show
CHEMBL48045644571103BindingDB-show
CHEMBL48045744571104BindingDB-show
CHEMBL48061744571149BindingDB-show
CHEMBL48061844571150BindingDB-show
CHEMBL48063044570971BindingDB-show
CHEMBL48064644571143BindingDB-show
CHEMBL48081344571188BindingDB-show
CHEMBL48081444571189BindingDB-show
CHEMBL48081544571190BindingDB-show
CHEMBL48082510291931BindingDB-show
CHEMBL48082644570972BindingDB-show
CHEMBL48100824759558BindingDB-show
CHEMBL48122244571018BindingDB-show
CHEMBL48122344571019BindingDB-show
CHEMBL48123044571098BindingDB-show
CHEMBL48123144571100BindingDB-show
CHEMBL48140044571105BindingDB-show
CHEMBL48140144571106BindingDB-show
CHEMBL48140244571144BindingDB-show
CHEMBL48140622170285BindingDB-show
CHEMBL48140722170188BindingDB-show
CHEMBL48142344571020BindingDB-show
CHEMBL48159544571146BindingDB-show
CHEMBL48159644571147BindingDB-show
CHEMBL48180616755780BindingDB-show
CHEMBL48199522170249BindingDB-show
CHEMBL48200010292887BindingDB-show
CHEMBL48219244570888BindingDB-show
CHEMBL4852859983303BindingDB-show
CHEMBL48528644580077BindingDB-show
CHEMBL4857459857146BindingDB-show
CHEMBL48884025065806BindingDB-show
CHEMBL49142923658582BindingDB-show
CHEMBL49572910479082BindingDB-show
CHEMBL49612944580358BindingDB-show
CHEMBL49735044580449BindingDB-show
CHEMBL49735344580778BindingDB-show
CHEMBL4975639864418BindingDB-show
CHEMBL50386622170298BindingDB-show
CHEMBL50780344593434BindingDB-show
CHEMBL51038611567957BindingDB-show
CHEMBL51238544561875BindingDB-show
CHEMBL51358844562058BindingDB-show
CHEMBL51660110155136BindingDB-show
CHEMBL51681344561878BindingDB-show
CHEMBL51706944571016BindingDB-show
CHEMBL51743723630085BindingDB-show
CHEMBL51753044570852BindingDB-show
CHEMBL51754422170205BindingDB-show
CHEMBL51876044571222BindingDB-show
CHEMBL51977910271800BindingDB-show
CHEMBL51992444571148BindingDB-show
CHEMBL52074244570851BindingDB-show
CHEMBL52092544570889BindingDB-show
CHEMBL52124810108847BindingDB-show
CHEMBL52125544571017BindingDB-show
CHEMBL52126244571187BindingDB-show
CHEMBL52140744571102BindingDB-show
CHEMBL52142244571099BindingDB-show
CHEMBL52173444580532BindingDB-show
CHEMBL52188744580689BindingDB-show
CHEMBL52257910089048BindingDB-show
CHEMBL52355944580420BindingDB-show
CHEMBL52663944580649BindingDB-show
CHEMBL53980718770789BindingDB-show
CHEMBL54133445265103BindingDB-show
CHEMBL54248411359024BindingDB-show
CHEMBL54295545261997BindingDB-show
CHEMBL54319518770817BindingDB-show
CHEMBL54366918770833BindingDB-show
CHEMBL54390418770840BindingDB-show
CHEMBL54530245261972BindingDB-show
CHEMBL54553818770814BindingDB-show
CHEMBL54577618770799BindingDB-show
CHEMBL55352345261998BindingDB-show
CHEMBL55390818770783BindingDB-show
CHEMBL55405318770774BindingDB-show
CHEMBL55456618770810BindingDB-show
CHEMBL57592544622967BindingDB-show
CHEMBL59129246228880BindingDB-show
CHEMBL997439911005BindingDB-show
CHIR-2589886808BindingDB-show
CHIR-26511656518BindingDB-show
CP-7247149874913BindingDB-show
Dasatinib3062316BindingDB-show
Doramapimod156422BindingDB-show
Erlotinib176870BindingDB-show
Gefitinib123631BindingDB-show
GW-258011617559BindingDB-show
Imatinib Methansulfonate5291BindingDB-show
Imatinib Methansulfonate5291DrugBank-show
kinase inhibitor-primary targets: CDK2, CDK9, other CDKs24867231BindingDB-show
Kinome_248146224684BindingDB-show
Kinome_71446886323BindingDB-show
Lapatinib ditosylate208908BindingDB-show
Lestaurtinib126565BindingDB-show
MLN805411712649BindingDB-show
N-methyl-N-phenyl-7H-purin-6-amine4350438BindingDB-show
N-[2-(4-methylpiperazin-1-yl)phenyl]-5-nitrofuran-2-carboxamide2039872BindingDB-show
N-[2-(piperidin-1-yl)phenyl]furan-2-carboxamide736073BindingDB-show
Nilotinib644241BindingDB-show
Pazopanib10113978BindingDB-show
Pelitinib6445562BindingDB-show
PI-1039884685BindingDB-show
PKC-41224202429BindingDB-show
PKC-4129829523BindingDB-show
Roscovitine160355BindingDB-show
Ruboxistaurin153999BindingDB-show
RWJ-3872525330790BindingDB-show
S1018_Selleck9977819BindingDB-show
S1147_Selleck16007391BindingDB-show
S1152_Selleck24180719BindingDB-show
S1526_Selleck24889392BindingDB-show
SB 2021905353940BindingDB-show
SB-4315424521392BindingDB-show
Semaxinib5329098BindingDB-show
SNS-0323025986BindingDB-show
sorafenibum216239BindingDB-show
staurosporine451705BindingDB-show
staurosporine44299148BindingDB-show
STK345368953649BindingDB-show
STK3555982995620BindingDB-show
STK3556022996093BindingDB-show
STK3556062996559BindingDB-show
SU-1481310138259BindingDB-show
Sunitinib5329102BindingDB-show
Sunitinib5329102DrugBank-show
Sunitinib malate6456015BindingDB-show
Tandutinib3038522BindingDB-show
Vandetanib3081361BindingDB-show
Vatalanib151194BindingDB-show
Vatalanib succinate151193BindingDB-show
VX-6805494449BindingDB-show
VX-7453038525BindingDB-show
ZINC00463429889132BindingDB-show
Synonyms:
c-fms
CD115
CSF-1-R
Fms proto-oncogene
Macrophage colony-stimulating factor 1 receptor
Similar targets:
Uniprot name% Sequence similarity% Sequence identity
KIT_HUMAN54.139.5
Q6IQ28_HUMAN5439.4
PGFRA_HUMAN46.230.7
PGFRB_HUMAN45.531.6
FLT3_HUMAN4530.8
Q99052_MOUSE3927.6
FGFR3_HUMAN37.327.1
VGFR1_HUMAN36.923.1
Q6P4H5_HUMAN36.622.4
VGFR2_HUMAN36.424.4
FGFR1_HUMAN35.824.2
FGFR2_HUMAN35.422.3
TYRO3_HUMAN34.622.8
FGFR1_MOUSE34.523.5
FGFR4_HUMAN34.323.8
VGFR3_HUMAN34.323
NTRK1_HUMAN3422.4
RET_HUMAN33.722.4
Q59F04_HUMAN33.424.3
DDR1_HUMAN33.121.2
EPHB1_HUMAN31.919.8
EPHB2_MOUSE31.819.9
BTK_HUMAN31.117.8
BRAF_HUMAN30.919.1
AMPN_HUMAN30.315.8
POL_EIAVY30.217.2
PDE2A_HUMAN29.916.8
NMDZ1_HUMAN29.917.8
KSYK_HUMAN29.818.9
AT1A4_MOUSE29.817
Protein-Protein Interactions: