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Target Details

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Name:CYPIIIA5
Uniprot name:CP3A5_HUMAN
Accession Numbers:P20815 Q53WY8 Q75MV0 Q9HB56
EC-Number:1.14.14.1
Organism:Homo sapiens
Human
PDB IDs:-
KEGG Pathways:show KEGG Pathways
Drugs:
NamePubChem IDSourceReferencesInteraction
Aethinyloestradiolum5991SuperCyp-show
Alfentanil51263DrugBank-show
Alfentanil51263SuperCypPMID 17554244show
Alprazolamum2118SuperCypPMID 15903124show
Amiodarone Hydrochloride2157SuperCyp-show
AMIODARONE HYDROCHLORIDE441325SuperCyp-show
Amlodipine Benzenesulfonate2162SuperCyp-show
Amprenavir65016PROMISCUOUS2 PMIDsshow
Amprenavir65016SuperCypPMID 12584153show
Androsteston5995SuperCyp2 PMIDsshow
Anhydrohydroxynorprogesterone6230PROMISCUOUSPMID 18356043show
Anhydrohydroxynorprogesterone4536PROMISCUOUSPMID 18356043show
Anhydrohydroxynorprogesterone6230SuperCypPMID 14663455show
Anhydrohydroxynorprogesterone4536SuperCypPMID 14663455show
Ansioxacepam4616SuperCypPMID 10659949show
Aprepitant151165SuperCyp-show
Argatroban152951SuperCypPMID 10234600show
Aripiprazole60795SuperCyp-show
Astemizole2247SuperCyp-show
Atorvastatin60823SuperCypPMID 16388406show
Aztreonam54117SuperCypPMID 8153141show
Aztreonam5362041SuperCypPMID 8153141show
Beclomethasone20469SuperCypPMID 12538830show
Beclomethasone11957468SuperCypPMID 12538830show
Beclomethasone2308SuperCypPMID 12538830show
Beclomethasone24867475SuperCypPMID 12538830show
Benzoylmethylecgonine5760SuperCyp-show
Benzoylmethylecgonine446220SuperCyp-show
Buspirone hydrochloride2477SuperCyp-show
Buspirone hydrochloride36431SuperCyp-show
Carbamazapine2756SuperCypPMID 10223772show
Carbamazepine2554SuperCypPMID 12673034show
Cerivastatin446156SuperCyp-show
cerivastatin23663992SuperCyp-show
Chloroprophenpyridamine2725SuperCyp-show
Chloroquinium2719SuperCypPMID 12967198show
Clarithromycin84029SuperCyp-show
CLARITHROMYCIN54688SuperCyp-show
Clorazolam5556PROMISCUOUSPMID 12814972show
Clorazolam5556SuperCypPMID 12814972show
Crystoserpine5770SuperCypPMID 8632764show
Cyclopentylrifampicin6323497SuperCypPMID 11432536show
CYCLOSPORINE6435893SuperCypPMID 12673034show
Demethyl Epipodophyllotoxin Ethylidine Glucoside36462SuperCypPMID 15319341show
Dexpropranolol4946SuperCyp-show
Dextromethadone4095SuperCyp-show
Dextromethadone643985SuperCyp-show
DEXTROMETHORPHAN5360696SuperCyp2 PMIDsshow
Diaminodiphenylsulfone2955SuperCyp-show
Dideoxycytidine24066SuperCypPMID 9084959show
diethylcarbamothioylsulfanyl diethylaminomethanedithioate3117SuperCypPMID 9756035show
Diethylparaoxon9395SuperCypPMID 16757081show
Diethylparaoxon9395SuperTarget-show
Diethyltoluamide4284SuperCypPMID 11854147show
Dihydrofolliculin5757SuperCyp-show
Dihydrohydroxycondeinone5284603SuperCypPMID 15039299show
Diltiazem hydrochloride39186PROMISCUOUS2 PMIDsshow
Diltiazem hydrochloride39186SuperCypPMID 10454485show
Diphenylhydatanoin1775PROMISCUOUS2 PMIDsshow
Diphenylhydatanoin1775SuperCypPMID 12673034show
Docetaxel148124SuperCyp-show
Domperidone Monohydrochloride3151SuperCyp-show
Dutasteride152945SuperCyp-show
Dutasteride6918296SuperCyp-show
Enteropride2769SuperCyp2 PMIDsshow
Epoxymexrenone150310SuperCyp-show
Ethylmethylsuccimide3291SuperCypPMID 12637244show
FELODIPINE3333PROMISCUOUSPMID 9153299show
Felodipine636806PROMISCUOUSPMID 9153299show
FELODIPINE3333SuperCyp-show
Felodipine636806SuperCyp-show
Fentanylum3345PROMISCUOUSPMID 8886601show
Fentanylum3345SuperCypPMID 16419387show
FINASTERIDE57363SuperCyp-show
FLUCONAZOLE3365PROMISCUOUSPMID 9929500show
Fluormethylprednisolone5743SuperCyp3 PMIDsshow
Fluvoxamine3404PROMISCUOUS7 PMIDsshow
Fluvoxamine5361192PROMISCUOUS7 PMIDsshow
Fluvoxamine3404SuperCypPMID 7742153show
Fluvoxamine5361192SuperCypPMID 7742153show
Furofutran5386SuperCypPMID 11095583show
Gelbkoerperhormon5994SuperCypPMID 10403825show
Granisetron Monohydrochloride3510SuperCypPMID 7888294show
Halofantrinum72454SuperCypPMID 10385214show
Haloperidol3559SuperCyp2 PMIDsshow
Hydrocorticosterone5754SuperCypPMID 16141800show
Imatinib Methansulfonate5291PROMISCUOUSPMID 16286749show
Imatinib Methansulfonate5291SuperCypPMID 16122278show
Indinavir60944PROMISCUOUS2 PMIDsshow
Indinavir5362440PROMISCUOUS2 PMIDsshow
Indinavir5462355PROMISCUOUS2 PMIDsshow
Indinavir60944SuperCyp2 PMIDsshow
Indinavir5362440SuperCyp2 PMIDsshow
Indinavir5462355SuperCyp2 PMIDsshow
Iproveratril2520SuperCyp2 PMIDsshow
irinotecan hydrochloride60838SuperCyp3 PMIDsshow
Irinotecan hydrochloride74990SuperCyp3 PMIDsshow
irinotecan hydrochloride60838SuperTargetPMID 012570720show
Irinotecan hydrochloride74990SuperTargetPMID 012570720show
KETOCONAZOLE47576SuperCyp3 PMIDsshow
Ketoconazole3823SuperCyp3 PMIDsshow
Ketoconazole456201SuperCyp3 PMIDsshow
Ketohydroxyoestrin5870SuperCypPMID 9635876show
Leurocristine5978SuperCypPMID 16679390show
Levacetylmethadol15130SuperCyp-show
Lidocaine Monohydrochloride3676PROMISCUOUSPMID 15845683show
Lidocaine Monohydrochloride3676SuperCyp-show
Losartan3961SuperCyp2 PMIDsshow
Lovastatin53232SuperCyp-show
Lovastatin3962SuperCyp-show
Methyldiazepinone3016SuperCyp2 PMIDsshow
Methylmorphine5284371SuperCyp-show
Methyltheobromide2519SuperCyp-show
Mibefradil60663SuperCyp2 PMIDsshow
Midazolam hydrochloride4192PROMISCUOUSPMID 16472102show
MIDAZOLAM HYDROCHLORIDE43032PROMISCUOUSPMID 16472102show
Midazolam hydrochloride4192SuperCyp2 PMIDsshow
MIDAZOLAM HYDROCHLORIDE43032SuperCyp2 PMIDsshow
Mifepristone55245SuperCyp2 PMIDsshow
Mifepristone16758830SuperCyp2 PMIDsshow
Mifepristone6712024SuperCyp2 PMIDsshow
MODAFINIL4236SuperCyp2 PMIDsshow
Nateglinide60026SuperCyp-show
Nateglinide443871SuperCyp-show
Nateglinide5311309SuperCyp-show
Nefazodone Hydrochloride4449SuperCypPMID 10445380show
NEFAZODONE HYDROCHLORIDE54911SuperCypPMID 10445380show
Nelfinavir64143PROMISCUOUSPMID 16433896show
Nelfinavir64143SuperCyp2 PMIDsshow
Neoperidole16362SuperCyp-show
Neoperidole52919SuperCyp-show
Nicardipine hydrochloride4474PROMISCUOUSPMID 15377640show
Nicardipine hydrochloride4474SuperCypPMID 15377640show
Nifedipine Monohydrochloride4485SuperCypPMID 12814972show
Nifedipine Monohydrochloride4485SuperTarget2 PMIDsshow
NimodipinISIS4497SuperCypPMID 11501176show
Nisoldipine4499SuperCyp-show
Nitrendipinratiopharm4507SuperCyp-show
Norfloxacine4539SuperCypPMID 8894516show
Norsynephrine4581SuperCypPMID 16419387show
NovoFlutamide3397SuperCypPMID 17403914show
ONDANSETRON HYDROCHLORIDE4595SuperCypPMID 8591723show
Oxcarbamazepine34312SuperCypPMID 12895138show
Oxibutyninum4634SuperCypPMID 9584328show
Paclitaxel36314SuperCyp-show
Phenethylhydrazine3675PROMISCUOUSPMID 16669850show
Phenethylhydrazine3675SuperCypPMID 16669850show
Phenylaethylbarbitursaeure4763SuperCyp2 PMIDsshow
Physostigmine5983SuperCypPMID 11514953show
Phytogermine14985SuperCypPMID 12763054show
Pravastatin54687SuperCypPMID 9929499show
Praziquantel4891SuperCypPMID 12426514show
PRAZIQUANTEL445900SuperCypPMID 12426514show
Quetiapine5002SuperCyp-show
Quinacrine Dihydrochloride237SuperCypPMID 16581945show
Quinineanhydrous8549SuperCyp-show
Ranitidine hydrochloride3001055PROMISCUOUSPMID 10223772show
Ranitidine hydrochloride3001055SuperCypPMID 10223772show
RAPAMYCIN IMMUNOSUPPRESSANT DRUG5284616SuperCyp-show
Rifampicinum5381226SuperCyp3 PMIDsshow
Risperidonum5073SuperCypPMID 11560868show
Ritonavir392622PROMISCUOUS2 PMIDsshow
Ritonavir392622SuperCyp3 PMIDsshow
Rosuvastatin6439133PROMISCUOUSPMID 16388406show
Rosuvastatin6439133SuperCypPMID 16388406show
Salicylazosulfapyridine5353980SuperCypPMID 9117175show
Salmeterol5152SuperCyp-show
SAQUINAVIR60787SuperCypPMID 16433896show
Sildenafil5212SuperCyp-show
SIMVASTATIN54454SuperCypPMID 9321523show
SPIRONOLACTONE/HYDROCHLOROTHIAZIDE5833SuperCypPMID 12011477show
Telithromycin5462516SuperCyp-show
Telithromycin3002190SuperCyp-show
TENIPOSIDE34698SuperCypPMID 8114683show
Teniposide5396SuperCypPMID 8114683show
Tetrahydrophenobarbital5838SuperCypPMID 8638929show
Tomaxithen2733526SuperCyp2 PMIDsshow
Trazodone Hydrochloride5533SuperCyp-show
Trazodone hydrochloride62935SuperCyp-show
Trichloraethylenum6575SuperTarget-show
TROGLITAZONE5591PROMISCUOUSPMID 15860655show
TROGLITAZONE5591SuperCyp2 PMIDsshow
Vardenafil110634PROMISCUOUSPMID 18308836show
Vardenafil110634SuperCypPMID 18308836show
Zaleplon5719SuperCyp-show
Ziprasidone hydrochloride60854SuperCyp-show
Ziprasidone hydrochloride219099SuperCyp-show
Zolpidem5732SuperCyp-show
Zonisamide5734SuperCypPMID 9626925show
Zotepine5736SuperCypPMID 10219963show
Synonyms:
CYPIIIA5
Cytochrome P450 3A5
HLp2
P450-PCN3
Similar targets:
Uniprot name% Sequence similarity% Sequence identity
Q53GC3_HUMAN99.699.6
Q6GRK0_HUMAN91.884.1
CP3A4_HUMAN91.884.1
Q86SK3_HUMAN91.783.5
CP3A7_HUMAN90.981.5
CP3A1_RAT85.772.2
CP3A2_RAT85.370.6
CP343_HUMAN84.975.5
Q7Z448_HUMAN78.972.8
Q86SK2_HUMAN64.458.4
THAS_RAT54.833.7
THAS_HUMAN54.834.1
THAS_MOUSE54.633.5
Q6ZN67_HUMAN46.125
CP4X1_HUMAN45.925.1
CP4F8_HUMAN45.726
CP4B1_RAT45.426.7
CP4AE_RAT44.125.9
CP4FC_HUMAN4425
Q8NAZ3_HUMAN43.623.1
CP4AB_HUMAN43.425.2
CP4F3_HUMAN43.125.2
CP46A_HUMAN42.824.7
CP4B1_HUMAN42.824.5
CP17A_HUMAN42.225.6
CP4AA_RAT42.225.4
CP4F2_HUMAN42.224.1
CP17A_RAT42.124.4
CP2CJ_HUMAN42.126.7
CP4FB_HUMAN42.124.5
Protein-Protein Interactions:
No data available