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Target Details

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Name:4-nitrophenol 2-hydroxylase
Uniprot name:CP2E1_HUMAN
Accession Numbers:P05181 Q5VZD5 Q9UK47
EC-Number:1.14.13.-
1.14.13.n7
Organism:Homo sapiens
Human
PDB IDs:3E4E 3E6I
KEGG Pathways:show KEGG Pathways
Drugs:
NamePubChem IDSourceReferencesInteraction
(NE)-N-[(5-pyridin-3-yl-2-furyl)methylidene]hydroxylamine11389855BindingDB-show
(NE)-N-[(5-pyridin-3-yl-2-furyl)methylidene]hydroxylamine11355925BindingDB-show
(NZ)-N-[(5-pyridin-3-ylthiophen-2-yl)methylidene]hydroxylamine11264173BindingDB-show
3,3'-Bipyridine68487BindingDB-show
3-(1H-Imidazol-4-yl)pyridine3040177BindingDB-show
3-(3-Thienyl)pyridine595254BindingDB-show
Acarbose441184SuperCyp-show
ACARBOSE41774SuperCyp-show
Acylcarnitine34756SuperCypPMID 15763544show
Adsorbocarpine5910SuperCyp-show
Adsorbocarpine5909SuperCyp-show
AI-942/25034651595145BindingDB-show
Alitretinoin444795SuperCyp-show
ALITRETINOIN449171SuperCyp-show
Allopurinol2094SuperCypPMID 7505583show
Allopurinol83786SuperCypPMID 7505583show
Alosetron2099SuperCyp-show
Amfebutamone444SuperCypPMID 10997944show
Amitriprolidine2160SuperCyp3 PMIDsshow
Anaesthesinum2337SuperCypPMID 8061946show
Arteriovinca15376SuperCypPMID 16176333show
Azelastine2267SuperCypPMID 10383922show
Benzydamine Monohydrochoride12555SuperCypPMID 11531003show
Benzylmethylpropargylamine4688SuperCypPMID 8114614show
Bromazepam2441SuperCyp-show
Bromochlorotrifluoroethane3562SuperCyp6 PMIDsshow
Carbamazapine2756SuperCyp4 PMIDsshow
Carvedilol2585SuperCypPMID 9280405show
CHEBI:4180411332763BindingDB-show
CHEBI:64937644410547BindingDB-show
CHEBI:64937744410548BindingDB-show
CHEBI:64938344410440BindingDB-show
CHEBI:64941444410603BindingDB-show
CHEBI:65312144410552BindingDB-show
CHEBI:65313044410573BindingDB-show
CHEMBL17868144388657BindingDB-show
CHEMBL17871111210706BindingDB-show
CHEMBL17878011207072BindingDB-show
CHEMBL17878144388612BindingDB-show
CHEMBL17900511389737BindingDB-show
CHEMBL17939810899427BindingDB-show
CHEMBL17939944388606BindingDB-show
CHEMBL17952944388719BindingDB-show
CHEMBL17966923646069BindingDB-show
CHEMBL17970411378800BindingDB-show
CHEMBL24423916072099BindingDB-show
CHEMBL2444039799417BindingDB-show
CHEMBL26621244428924BindingDB-show
CHEMBL35965711206290BindingDB-show
CHEMBL36099911344157BindingDB-show
CHEMBL36136411480732BindingDB-show
CHEMBL36270215778480BindingDB-show
CHEMBL36888316654686BindingDB-show
CHEMBL42551911389927BindingDB-show
CHEMBL59376323657438BindingDB-show
Chlormethiazole10783SuperCyp2 PMIDsshow
Chlorzoxazone2733SuperCyp10 PMIDsshow
Chlorzoxazone2733SuperTargetPMID 016221755show
Chlotrimazole2812SuperCyp2 PMIDsshow
Cisclomiphene1548955SuperCypPMID 9054622show
Citalopram Hydrobromide2771SuperCypPMID 12692778show
Clozapine2818SuperCyp-show
Colchicinum6167SuperCypPMID 11144118show
Conquinine5953SuperCypPMID 10086984show
Demethyl Epipodophyllotoxin Ethylidine Glucoside36462SuperCypPMID 9732391show
Desmethylamitriptyline4543SuperCyp2 PMIDsshow
Dextrofenfluramine3337SuperCypPMID 9690701show
DEXTROMETHORPHAN5360696SuperCyp-show
Diaethylaether3283SuperCypPMID 8452561show
Diaminodiphenylsulfone2955SuperCyp2 PMIDsshow
Dichlofenac3033SuperCyp2 PMIDsshow
diethylcarbamothioylsulfanyl diethylaminomethanedithioate3117SuperCyp9 PMIDsshow
diethylcarbamothioylsulfanyl diethylaminomethanedithioate3117SuperTarget2 PMIDsshow
Diethylparaoxon9395SuperCypPMID 8615874show
Diethylparaoxon9395SuperTarget-show
Diethyltoluamide4284SuperCypPMID 11854147show
Dihydroxyanthraquinone4212SuperCyp-show
Dihydroxyanthraquinone2950SuperCyp-show
Dihydroxyanthraquinone6293SuperCyp-show
Diisopropylphenol4943SuperCyp2 PMIDsshow
Dimethylcarbinol3776SuperCyp2 PMIDsshow
Dimethyloxyquinazine2206SuperCypPMID 8801065show
Dimethyltriazenoimidazolecarboxamide5351166SuperCyp2 PMIDsshow
Dinitroisosorbide6883SuperCypPMID 16621933show
Diurnaldiverondormabrol4064SuperCypPMID 11752126show
Diurobromine5429SuperCypPMID 10215755show
DL-tetrahydronicotyrine942SuperCyp4 PMIDsshow
DORZOLAMIDE92087SuperCypPMID 7895610show
Dorzolamide3154SuperCypPMID 7895610show
Dorzolamide5284549SuperCypPMID 7895610show
Econazole3198SuperCyp2 PMIDsshow
Entacapone5281081SuperCyp-show
Enterosalicyl16760658SuperCypPMID 8571407show
eszopiclone5735SuperCypPMID 16750462show
Eszopiclone969472SuperCypPMID 16750462show
Ethyl chlorophenoxyisobutyrate2796SuperCyp2 PMIDsshow
Ethylmethylsuccimide3291SuperCypPMID 12637244show
Etoricoxib123619SuperCypPMID 11353749show
Felbamate3331SuperCyp2 PMIDsshow
Flufenaminsaeure3371SuperCypPMID 9294022show
Flumequine3374SuperCypPMID 16468039show
Fluormethylprednisolone5743SuperCyp2 PMIDsshow
fluoromethyl hexafluoroisopropyl ether5206SuperCyp6 PMIDsshow
Fluorophenazine3372SuperCyp2 PMIDsshow
Fluoxetine Hydrochloride3386SuperCyp3 PMIDsshow
Flurazepam Dihydrochloride3393SuperCypPMID 9574817show
Fluvoxamine3404SuperCypPMID 12692778show
Fluvoxamine5361192SuperCypPMID 12692778show
Fomepizole3406SuperCyp6 PMIDsshow
Furofutran5386SuperCypPMID 11095583show
GLUCOSAMINE HYDROCHLORIDE441477SuperCypPMID 11531003show
Hydroxyacetanilide1983SuperCyp5 PMIDsshow
Hydroxyacetanilide1983SuperTarget2 PMIDsshow
Hydroxymesterone247839SuperCypPMID 16476124show
Hydroxymesterone4043SuperCypPMID 16476124show
Hydroxymethoxybenzyl pelargonamide2998SuperCypPMID 12641434show
Intraconazole55283SuperCypPMID 9574817show
Ipriflavone3747SuperCypPMID 7588993show
Isoflurane3763SuperCyp2 PMIDsshow
ISOFLURANE4369440SuperCyp2 PMIDsshow
Isonicotinoylhydrazine3767SuperCyp10 PMIDsshow
Ketohydroxyoestrin5870SuperCypPMID 10640505show
Largactilothiazine2726SuperCypPMID 9574817show
Levocarnitine10917SuperCypPMID 8130774show
Levocarnitine288SuperCypPMID 8130774show
Medazepam Monohydrochloride4041SuperCypPMID 9574817show
Methazolamide4100SuperCypPMID 14739663show
Methbipyranone4174SuperCypPMID 7931342show
Methotrimeprazine72287SuperCypPMID 11985335show
Methoxifluranum4116SuperCyp3 PMIDsshow
Methylaminopropyliminodibenzyl2995SuperCyp2 PMIDsshow
Methylcarbinol702SuperCyp9 PMIDsshow
Methylflurether3226SuperCyp2 PMIDsshow
Methylmercaptoimidazole1349907SuperCyp2 PMIDsshow
Methylnaphthoquinone4055SuperCypPMID 14767997show
Methyltheobromide2519SuperCypPMID 8204093show
Methyltheobromide2519SuperTargetPMID 001302044show
Mexiletene hydrochloride4178SuperCypPMID 12519691show
Miconazole4189SuperCypPMID 16141569show
Minoaleuiatin5576SuperCyp4 PMIDsshow
Mizolastine65906SuperCyp2 PMIDsshow
Monoaethanolamini oleas6433328SuperCypPMID 16878272show
Monohydroxybenzene996SuperCyp7 PMIDsshow
Natriumchlorid5234SuperCypPMID 16434548show
Neoperidole16362SuperCyp-show
Neoperidole52919SuperCyp-show
Nicardipine hydrochloride4474SuperCypPMID 11996015show
Nifedipine Monohydrochloride4485SuperCypPMID 10805063show
Nikotinsaeureamid936SuperCypPMID 15081432show
NILVADIPINE4494SuperCypPMID 14993813show
Norchlorimipramine3696SuperCyp2 PMIDsshow
ONDANSETRON HYDROCHLORIDE4595SuperCypPMID 8723743show
Oxalatoplatinum9887054SuperCypPMID 14646291show
Parabromdylamine6834SuperCyp-show
Paracarbinoxamine2564SuperCyp-show
Paracetophenetidin4754SuperCypPMID 10421611show
parachlorometaxylenol2723SuperCypPMID 11996015show
Pernazine4744SuperCypPMID 11985335show
Phenylaethylbarbitursaeure4763SuperCyp3 PMIDsshow
Phytogermine14985SuperCypPMID 10232825show
Proguanil4923SuperCypPMID 10417492show
Pseudotheophylline2153SuperCyp2 PMIDsshow
Pteroylmonoglutamate6037SuperCypPMID 15705656show
Pteroylmonoglutamate3405SuperCypPMID 15705656show
Relaspium3034812SuperCypPMID 10628907show
Rifampicinum5381226SuperCypPMID 12642468show
Ritonavir392622SuperCyp-show
Selegiline hydrochloride26757SuperCyp3 PMIDsshow
Sildenafil5212SuperCyp-show
Sodium Ursodeoxycholate31401SuperCypPMID 12143038show
STREPTOZOTOCIN29327SuperCypPMID 15964029show
Streptozotocin5300SuperCypPMID 15964029show
Sulconazole5318SuperCyp-show
Sulfanilamidopyrimidine5215SuperCypPMID 11996015show
sulfurothioate1084SuperCypPMID 17222524show
Sulphanilamide5333SuperCypPMID 14739663show
tariquidarth148201BindingDB-show
Tegaserod5487301SuperCypPMID 11560869show
Tetramethylthiocarbamoyldisulphide5455SuperCypPMID 12458634show
Theophyllaminium9433SuperCyp-show
Thiopentobarbitone3000715SuperCypPMID 9784924show
Thioridazine Hydrochloride5452SuperCypPMID 9574817show
Tibolone444008SuperCypPMID 11792677show
TICLOPIDINE HYDROCHLORIDE5472SuperCyp-show
Ticlopidine hydrochloride65335SuperCyp-show
Tioconazole5482SuperCypPMID 11854151show
Tomaxithen2733526SuperCypPMID 8293548show
Tranylcypromine441233SuperCypPMID 15155557show
Tranylcypromine5530SuperCypPMID 15155557show
Trichloormethaan6212SuperCyp5 PMIDsshow
Trichloormethaan6212SuperTargetPMID 015129551show
Trichloraethylenum6575SuperCyp5 PMIDsshow
Trichloraethylenum6575SuperTarget2 PMIDsshow
Trifonazole2378SuperCyp2 PMIDsshow
Trihydroxypropane753SuperCypPMID 9113273show
Zafirlukast5717SuperCypPMID 10870095show
Synonyms:
4-nitrophenol 2-hydroxylase
CYPIIE1
Cytochrome P450 2E1
P450-J
Similar targets:
Uniprot name% Sequence similarity% Sequence identity
Q3YA63_HUMAN99.899.8
Q6NWT7_HUMAN99.699.6
Q6NWT9_HUMAN99.699.6
CP2CJ_HUMAN75.156.5
CP2CI_HUMAN74.356.5
CP2C9_HUMAN74.357.1
Q5VX92_HUMAN74.357.1
CP2C8_HUMAN73.156.1
CP2C5_RABIT72.554.3
CP2CB_RAT72.255.7
CP2C6_RAT72.154.7
CP2F1_HUMAN68.847.8
CP2A5_MOUSE67.347.2
CP2A6_HUMAN67.147.5
CP2B6_HUMAN66.845.6
CP2AD_HUMAN66.547.5
CP2B1_RAT66.548.3
CP2A7_HUMAN66.346.1
CP2B4_RABIT65.546.2
CP2S1_HUMAN58.840.2
Q6NWU0_HUMAN57.539.9
CP2D6_HUMAN57.539.9
CP2J2_HUMAN57.538.8
Q38LG0_HUMAN57.339.7
Q38LG2_HUMAN57.139.3
CP2W1_HUMAN56.338
CP2D1_RAT56.236.6
Q16743_HUMAN54.842.2
CP2R1_HUMAN54.735.1
Q6XP50_HUMAN54.236.9
Protein-Protein Interactions: