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Target Details

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Name:(R)-limonene 6-monooxygenase
Uniprot name:CP2CJ_HUMAN
Accession Numbers:P33259 P33261 Q8WZB1 Q8WZB2 Q9UCD4
EC-Number:1.14.13.48
1.14.13.49
1.14.13.80
Organism:Homo sapiens
Human
PDB IDs:-
KEGG Pathways:show KEGG Pathways
Drugs:
NamePubChem IDSourceReferencesInteraction
(2E)-3-[4-({[1-({[1-Cyclohexyl-2-(3-furyl)-1H-benzimidazol-5-yl]carbonyl}a6479956BindingDB-show
(NE)-N-[(5-pyridin-3-yl-2-furyl)methylidene]hydroxylamine11389855BindingDB-show
(NE)-N-[(5-pyridin-3-yl-2-furyl)methylidene]hydroxylamine11355925BindingDB-show
(NZ)-N-[(5-pyridin-3-ylthiophen-2-yl)methylidene]hydroxylamine11264173BindingDB-show
1-(4-butoxyphenyl)imidazole11321889BindingDB-show
3,3'-Bipyridine68487BindingDB-show
3-(1H-Imidazol-4-yl)pyridine3040177BindingDB-show
3-(3-Thienyl)pyridine595254BindingDB-show
3-Amino-4,6-dimethylthieno[2,3-b]pyridine-2-carboxamide613528BindingDB-show
3-aminothieno[2,3-b]pyridine-2-carboxamide359052BindingDB-show
3-butyryl-7- methoxycoumarin9964836BindingDB-show
357262-60-35495793BindingDB-show
37672-04-1181536BindingDB-show
5-(Methylthio)-1-(3-pyridylcarbamoyl)-6-(trifluoromethyl)indoline443389BindingDB-show
860642-69-923653789BindingDB-show
A-79074211228293BindingDB-show
AC1LA5VG507751BindingDB-show
AC1LA5WV507791BindingDB-show
AC1LAMJW491206BindingDB-show
AC1MHVAD3012020BindingDB-show
AC1MHVAV3012027BindingDB-show
AC1O58TB6479971BindingDB-show
Acetylsalicylsaeure2244SuperCypPMID 12621391show
ADINAZOLAM37632SuperCypPMID 9600717show
Aethinyloestradiolum5991SuperCyp2 PMIDsshow
Aformoterol6437070SuperCyp-show
aformoterol3034756SuperCyp-show
AI-942/25034651595145BindingDB-show
AIDS171253507783BindingDB-show
AIDS2098503008866BindingDB-show
AIDS2213636479949BindingDB-show
Aminoglutethimide2145SuperCyp-show
Amiodarone Hydrochloride2157SuperCypPMID 11038157show
AMIODARONE HYDROCHLORIDE441325SuperCypPMID 11038157show
Amitriprolidine2160SuperCyp5 PMIDsshow
Amitriprolidine2160SuperTarget2 PMIDsshow
Amodiachinum2165BindingDB-show
Amprenavir65016SuperCypPMID 11996015show
Anastrozole2187SuperTargetPMID 17667146show
Androsteston5995SuperCyp2 PMIDsshow
Anhydrohydroxynorprogesterone6230SuperCyp-show
Anhydrohydroxynorprogesterone4536SuperCyp-show
ApoGemfibrozil3463SuperCypPMID 11602509show
Apremilast11561674BindingDB-show
Aprepitant151165SuperCypPMID 15304427show
ASN 059157793213696BindingDB-show
Atomoxetine54841SuperCyp-show
Atomoxetine6850813SuperCyp-show
Azelastine2267SuperCyp2 PMIDsshow
azidodeoxythymidine35370SuperCyp2 PMIDsshow
Benzatropine6832SuperCypPMID 17003230show
Benzbromaronratiopharm2333BindingDB-show
Benzethoniumchloride8478SuperCypPMID 17003230show
Benzethoniumchloride2335SuperCypPMID 17003230show
Benzydamine Monohydrochoride12555SuperCyp2 PMIDsshow
Bicalutamide2375SuperCypPMID 15509184show
BICALUTAMIDE56069SuperCypPMID 15509184show
Blocadren33624SuperCypPMID 17431033show
Blocadren5281056SuperCypPMID 17431033show
BMS-488043507806BindingDB-show
BMS-53692410390396BindingDB-show
BMS-68745316725047BindingDB-show
BMS-75480724785538BindingDB-show
BMS-8065495818BindingDB-show
Bortezomib93860SuperCyp2 PMIDsshow
Bortezomib387447SuperCyp2 PMIDsshow
Bromazepam2441SuperCypPMID 9435993show
Buflomedil hydrochloride2467SuperCyp2 PMIDsshow
Buflomedil hydrochloride6420013SuperCyp2 PMIDsshow
BUPRENORPHINE40400SuperCyp-show
Buprenorphine5311033SuperCyp-show
Butacortelone3672SuperCyp2 PMIDsshow
Carbamazapine2756SuperCyp3 PMIDsshow
Carbamazepine2554SuperCyp2 PMIDsshow
cBupivacaine2474SuperCypPMID 10725304show
CHEBI:4180411332763BindingDB-show
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CHEMBL107619246879432BindingDB-show
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CHEMBL107859545102708BindingDB-show
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CHEMBL59864425210873BindingDB-show
CHEMBL59882625025775BindingDB-show
CHEMBL59945825181450BindingDB-show
CHEMBL59979125057933BindingDB-show
CHEMBL59979225054032BindingDB-show
CHEMBL60248317754437BindingDB-show
CHEMBL60408525057667BindingDB-show
CHEMBL60408725057409BindingDB-show
CHEMBL60424925054568BindingDB-show
CHEMBL60520925025977BindingDB-show
CHEMBL60815125025581BindingDB-show
CHEMBL60826324825713BindingDB-show
CHEMBL61079545379947BindingDB-show
CHEMBL6281113728862BindingDB-show
Chloramphenicolum5959SuperCypPMID 14576103show
Chlordesmethyldiazepam2997SuperCyp3 PMIDsshow
Chlorepin2789SuperCyp4 PMIDsshow
Chlormadinone9324SuperCyp-show
Chlormethiazole10783SuperCypPMID 11996015show
Chloropropamide2727SuperCypPMID 15842554show
Chlorperphenazine4748SuperCypPMID 11136295show
Chlotrimazole2812SuperCyp-show
Cholecalciferol6221SuperCypPMID 10219964show
CID 1021827811238080BindingDB-show
CID 1127437411274374BindingDB-show
CID 1146583411465834BindingDB-show
CID 1166568911615459BindingDB-show
CID 1199630311996303BindingDB-show
CID 1199630411996304BindingDB-show
CID 46729169833312BindingDB-show
Cidoxepinum667477SuperCyp2 PMIDsshow
Citalopram Hydrobromide2771SuperCyp3 PMIDsshow
Claratyne Decongestant3957SuperCypPMID 11502723show
Clarithromycin84029SuperCyp2 PMIDsshow
CLARITHROMYCIN54688SuperCyp2 PMIDsshow
CLOTIAZEPAM2811SuperCypPMID 16141545show
Clozapine2818SuperCyp3 PMIDsshow
Clozapine2818SuperTarget2 PMIDsshow
cyanoguanidine, 344249821BindingDB-show
Cyclophosphoramide2907SuperCyp6 PMIDsshow
cyclosporin A5284373BindingDB-show
CYCLOSPORINE6435893SuperCypPMID 17202802show
Dehydrocortisone5865SuperCypPMID 679598show
Delavirdine5625SuperCyp2 PMIDsshow
Deoxyepinephrine681SuperCypPMID 10813809show
Deoxyepinephrine4382SuperCypPMID 10813809show
Descarboethoxyloratadine124087SuperCypPMID 11502723show
Desmethylamitriptyline4543SuperCyp2 PMIDsshow
Desogestrel40973SuperCypPMID 9864282show
Desoxyphenobarbitone4909SuperCypPMID 10380060show
dexlansoprazole3883SuperCyp9 PMIDsshow
dexlansoprazole3883SuperTarget2 PMIDsshow
Dexpropranolol4946SuperCyp2 PMIDsshow
dexrabeprazole5029SuperCyp8 PMIDsshow
Dextrofenfluramine3337SuperCypPMID 9825834show
Dextromethadone4095SuperCypPMID 12900870show
Dextromethadone643985SuperCypPMID 12900870show
DEXTROMETHORPHAN5360696SuperCyp2 PMIDsshow
DG-04111296282BindingDB-show
Diaminodiphenylsulfone2955SuperCypPMID 10901692show
Dichlofenac3033SuperCyp2 PMIDsshow
Diethyltoluamide4284SuperCypPMID 11854147show
Dihydrofolliculin5757SuperCyp2 PMIDsshow
Dihydroxypyrimidine, 1316215970BindingDB-show
Diisopropylphenol4943SuperCypPMID 9771309show
Dimethylaminophenyldimethylpyrazolone6009SuperCyp2 PMIDsshow
Dimethylcarbinol3776SuperCypPMID 11996015show
Dimethyloxyquinazine2206SuperCyp2 PMIDsshow
Diphenylhydatanoin1775SuperCyp4 PMIDsshow
Diphenylhydatanoin1775SuperTargetPMID 012228186show
Dipropylacetate3121SuperCyp3 PMIDsshow
Dirlotapide9917862BindingDB-show
Diurnaldiverondormabrol4064SuperCypPMID 12835613show
DL-tetrahydronicotyrine942SuperCypPMID 10350185show
DMZ447297BindingDB-show
Doxazosin3157SuperCyp-show
doxazosin6604102SuperCyp-show
Efavirenz64139SuperCyp2 PMIDsshow
EFAVIRENZ3203SuperCyp2 PMIDsshow
Entacapone5281081SuperCyp-show
Enteropride2769SuperCyp2 PMIDsshow
Escitalopram146570SuperCypPMID 15057659show
Esomeprazole4594SuperCyp17 PMIDsshow
Ethotoin3292SuperCypPMID 2879902show
ETONOGESTREL40976SuperTargetPMID 012899669show
Etonogestrel6917715SuperTargetPMID 012899669show
Etoricoxib123619SuperCypPMID 11353749show
Felbamate3331SuperCyp2 PMIDsshow
Felbamate3331SuperTarget2 PMIDsshow
FLUCONAZOLE3365SuperCyp2 PMIDsshow
Flunitrazepam3380SuperCyp4 PMIDsshow
Flunitrazepam3380SuperTarget2 PMIDsshow
Fluormethylprednisolone5743SuperCypPMID 12869636show
Fluoxetine Hydrochloride3386SuperCyp3 PMIDsshow
Fluoxetine Hydrochloride3386SuperTarget2 PMIDsshow
Fluvoxamine3404SuperCyp3 PMIDsshow
Fluvoxamine5361192SuperCyp3 PMIDsshow
Fluvoxamine3404SuperTarget2 PMIDsshow
Fluvoxamine5361192SuperTarget2 PMIDsshow
Fosamprenavir131536SuperCyp-show
Fosphenytoin56339SuperCyp-show
Gastrodomina3325SuperCypPMID 17112810show
Gastrodomina5702160SuperCypPMID 17112810show
Gefitinib123631SuperCyp-show
Gelbkoerperhormon5994SuperCyp4 PMIDsshow
GLICLAZIDE3475SuperCypPMID 17298483show
GLUCOSAMINE HYDROCHLORIDE441477SuperCypPMID 11531003show
Glybenzcyclamide3488SuperCyp2 PMIDsshow
Glydiazinamide3478SuperCypPMID 10208645show
Gosogliptin (USAN/INN)11516136BindingDB-show
GSK-269984A23696973BindingDB-show
GW-34309826520BindingDB-show
GW-848687X10238338BindingDB-show
Haloperidol3559SuperCypPMID 11717183show
Huanghuahaosu68827SuperCyp2 PMIDsshow
Hydroxyampicillin33613SuperCypPMID 11240980show
Hydroxydiazepam5391SuperCypPMID 8948091show
Hydroxymesterone247839SuperCypPMID 16476124show
Hydroxymesterone4043SuperCypPMID 16476124show
Hydroxymethoxybenzyl pelargonamide2998SuperCypPMID 12641434show
Imatinib Methansulfonate5291SuperCyp-show
Indinavir60944SuperCyp2 PMIDsshow
Indinavir5362440SuperCyp2 PMIDsshow
Indinavir5462355SuperCyp2 PMIDsshow
Indomethacinum3715SuperCypPMID 9492390show
Ipriflavone3747SuperCypPMID 17624023show
Iproveratril2520SuperCypPMID 8750925show
Isonicotinoylhydrazine3767SuperCyp2 PMIDsshow
Isonipecaine4058SuperCypPMID 15319333show
Isophosphamide3690SuperCypPMID 10348794show
Isopropylmeprobamate2576SuperCypPMID 12835613show
Ketobemidonum10101SuperCypPMID 16278191show
Ketobemidonum10101SuperTargetPMID 16278191show
KETOCONAZOLE47576SuperCyp4 PMIDsshow
Ketoconazole3823SuperCyp4 PMIDsshow
Ketoconazole456201SuperCyp4 PMIDsshow
Lafutidine5282136SuperCypPMID 14653835show
LAMOTRIGINE3878SuperCypPMID 12708941show
Letrozole3902SuperTarget-show
Lopinavir92727SuperCypPMID 12724045show
Losartan3961SuperCypPMID 10877007show
Lumiracoxib151166SuperCypPMID 16372823show
M0517751819BindingDB-show
Medazepam Monohydrochloride4041SuperCypPMID 18175099show
Melatonine896SuperCyp3 PMIDsshow
MEMANTINE HYDROCHLORIDE4054SuperCypPMID 15378224show
Methazolamide4100SuperCypPMID 14739663show
METHSUXIMIDE6476SuperCyp2 PMIDsshow
Methylaminopropyliminodibenzyl2995SuperCyp2 PMIDsshow
Methylaminopropyliminodibenzyl2995SuperTargetPMID 009084457show
Methylcarbinol702SuperCypPMID 9929510show
Methyldiazepinone3016SuperCyp7 PMIDsshow
Methyldiazepinone3016SuperTargetPMID 011038161show
Methyldiphenylhydramine4601SuperCypPMID 9172960show
Methylhexabarbital3608SuperCypPMID 17487889show
Methylmercaptoimidazole1349907SuperCypPMID 9172960show
Methylphenobarbitonum8271SuperCyp4 PMIDsshow
Methylphenylsuccinimide6839SuperCypPMID 2879902show
Methylsulfinylmethane679SuperCypPMID 9929510show
Metoprolol4171SuperCypPMID 11996015show
Miconazole4189SuperCyp2 PMIDsshow
Midalcipran65833SuperTargetPMID 16122284show
Minoaleuiatin5576SuperCyp-show
MODAFINIL4236SuperCyp2 PMIDsshow
Monochlorimipramine2801SuperCyp3 PMIDsshow
Monochlorimipramine2801SuperTarget2 PMIDsshow
Monodesethylamodiaquine122068BindingDB-show
N-3-benzylnirvanol4804492BindingDB-show
Nelfinavir64143SuperCyp2 PMIDsshow
Neoperidole16362SuperCyp-show
Neoperidole52919SuperCyp-show
Nicardipine hydrochloride4474SuperCyp2 PMIDsshow
Nilutamide4493SuperCypPMID 1785203show
NILVADIPINE4494SuperCypPMID 14993813show
Norchlorimipramine3696SuperCyp8 PMIDsshow
Norchlorimipramine3696SuperTarget2 PMIDsshow
NovoFlutamide3397SuperCypPMID 17403914show
NovoMoclobemide4235SuperCyp4 PMIDsshow
NovoMoclobemide4235SuperTargetPMID 012595913show
NSC197105304583BindingDB-show
Olanzapine4585SuperCypPMID 8866916show
Oxcarbamazepine34312SuperCyp2 PMIDsshow
Oxcarbamazepine34312SuperTargetPMID 14731060show
Paliflutine24946690BindingDB-show
Pantoprazole4679SuperCyp9 PMIDsshow
Pantoprazole4679SuperTarget2 PMIDsshow
Parabromdylamine6834SuperCyp-show
Paracarbinoxamine2564SuperCyp-show
Paracetophenetidin4754SuperCyp2 PMIDsshow
Paroxetine43815SuperCypPMID 11910269show
PDSP1_0015693644637BindingDB-show
Pentobarbiturate4737SuperCypPMID 10805060show
Pernazine4744SuperCyp2 PMIDsshow
PF-0086855416099590BindingDB-show
Phenethylhydrazine3675SuperCypPMID 16669850show
Phenofibrate3339SuperCyp-show
Phenothiazine4926SuperCypPMID 12721102show
Phenylaethylbarbitursaeure4763SuperCyp3 PMIDsshow
Phenylethylmethylhydantoin4060SuperCyp3 PMIDsshow
Phenylethylmethylhydantoin4060SuperTargetPMID 016122284show
Pioglitazone Hydrochloride4829SuperCyp-show
Praziquantel4891SuperCypPMID 12920490show
PRAZIQUANTEL445900SuperCypPMID 12920490show
Probampacin4911SuperCypPMID 710028show
Proguanil4923SuperCyp5 PMIDsshow
Quazepamum4999SuperCypPMID 15801544show
Quetiapine5002SuperCypPMID 15516294show
Quinineanhydrous8549SuperCyp2 PMIDsshow
Ranitidine hydrochloride3001055SuperCypPMID 11128045show
Rattentraenke6691SuperCyp2 PMIDsshow
Relaspium3034812SuperCypPMID 10628907show
Retinol1071SuperCypPMID 10219964show
Rifampicinum5381226SuperCyp2 PMIDsshow
Ritonavir392622SuperCyp2 PMIDsshow
Rosigilitazone77999SuperCypPMID 12642470show
S1519_Selleck16202152BindingDB-show
SAQUINAVIR60787SuperCypPMID 9549640show
SB 206553 hydrochloride5163BindingDB-show
SB 243213443391BindingDB-show
SB-2141116918647BindingDB-show
SB-2710466918455BindingDB-show
Schering compound 28080108137BindingDB-show
SCY-63549863459BindingDB-show
Sedekopan3307SuperCypPMID 17635335show
Selegiline hydrochloride26757SuperCyp3 PMIDsshow
SERATRODAST2449SuperCypPMID 9010637show
Sertraline Hydrochloride68617SuperCyp8 PMIDsshow
Sertraline hydrochloride63009SuperCyp8 PMIDsshow
Sertraline Hydrochloride68617SuperTargetPMID 010510155show
Sertraline hydrochloride63009SuperTargetPMID 010510155show
Sildenafil5212SuperCypPMID 10725306show
Spectrum_0000462166BindingDB-show
STK32034317027464BindingDB-show
Sulconazole5318SuperCypPMID 11854151show
Sulfaphenylpyrazole5335BindingDB-show
Sulphanilamide5333SuperCypPMID 14739663show
tariquidarth148201BindingDB-show
Telmisartan65999SuperCyp-show
TENIPOSIDE34698SuperCyp-show
Teniposide5396SuperCyp-show
Terbinafine hydrochloride5402SuperCypPMID 10460803show
Terbinafine hydrochloride5282481SuperCypPMID 10460803show
Tetrabenazine6018SuperCypPMID 15232626show
Tetrahydrocannabinols16078SuperCyp3 PMIDsshow
Tetrahydrocannabinols2977SuperCyp3 PMIDsshow
Theophilcholine5426SuperCyp2 PMIDsshow
Thioridazine Hydrochloride5452SuperCyp-show
TICLOPIDINE HYDROCHLORIDE5472SuperCyp8 PMIDsshow
Ticlopidine hydrochloride65335SuperCyp8 PMIDsshow
TICLOPIDINE HYDROCHLORIDE5472SuperTarget2 PMIDsshow
Ticlopidine hydrochloride65335SuperTarget2 PMIDsshow
Tioconazole5482SuperCypPMID 11854151show
Tocris-1375443390BindingDB-show
TOLPERISONE5511SuperCypPMID 12695352show
Tolterodine60774SuperCypPMID 9531513show
Tolterodine443878SuperCypPMID 9531513show
Tolterodine443879SuperCypPMID 9531513show
Tolylsulfonylbutylurea5505SuperCyp2 PMIDsshow
Tomaxithen2733526SuperCypPMID 16550168show
Topiramate5284627SuperCyp2 PMIDsshow
Torasemide41781SuperCyp-show
tranylcypromine19493BindingDB-show
Tranylcypromine441233SuperCyp3 PMIDsshow
Tranylcypromine5530SuperCyp3 PMIDsshow
Tranylcypromine441233SuperTarget2 PMIDsshow
Tranylcypromine5530SuperTarget2 PMIDsshow
Triacetyloleandomycin202225SuperCypPMID 15054565show
Trichloormethaan6212SuperCypPMID 11996015show
Trifonazole2378SuperCyp-show
trimeproprimine5584SuperCypPMID 14520122show
TROGLITAZONE5591SuperCyp2 PMIDsshow
UNII-E0OU4SC8DP9951066BindingDB-show
Valdecoxib119607SuperCyp-show
VenlafaxineXR5656SuperCypPMID 10192828show
Voriconazole71616SuperCyp4 PMIDsshow
WAY-18118710150497BindingDB-show
Zafirlukast5717SuperCypPMID 10870095show
ZINC00073452697226BindingDB-show
ZINC025397642756534BindingDB-show
ZINC025650732782903BindingDB-show
ZINC044018963530525BindingDB-show
Zonisamide5734SuperCyp2 PMIDsshow
Zotepine5736SuperCypPMID 10219963show
Synonyms:
(R)-limonene 6-monooxygenase
(S)-limonene 6-monooxygenase
(S)-limonene 7-monooxygenase
CYPIIC17
CYPIIC19
Cytochrome P450 2C19
Mephenytoin 4-hydroxylase
P450-11A
P450-254C
Similar targets:
Uniprot name% Sequence similarity% Sequence identity
CP2C9_HUMAN95.391.2
Q5VX92_HUMAN95.391.2
CP2CI_HUMAN91.881
CP2C5_RABIT8876.3
CP2C6_RAT87.875.3
CP2C8_HUMAN87.878
CP2CB_RAT85.473
CP2E1_HUMAN75.156.5
Q3YA63_HUMAN75.156.5
Q6NWT7_HUMAN74.956.3
Q6NWT9_HUMAN74.756.1
CP2F1_HUMAN71.151.1
CP2B4_RABIT70.550.1
CP2A5_MOUSE7051.2
CP2A6_HUMAN69.950.5
Q16743_HUMAN69.866.5
CP2AD_HUMAN69.650.6
CP2B1_RAT6950.3
CP2A7_HUMAN68.848.8
CP2B6_HUMAN68.248.1
CP2S1_HUMAN62.343.3
CP2D1_RAT58.438.5
Q6NWU0_HUMAN5839.6
CP2D6_HUMAN5839.6
Q38LG0_HUMAN57.839.4
Q38LG2_HUMAN57.639.4
CP2W1_HUMAN57.236.5
CP2J2_HUMAN55.738.1
Q6XP50_HUMAN54.937.2
Q9UEH3_HUMAN53.750.8
Protein-Protein Interactions:
Uniprot nameSource
NCPR_HUMANPMID 9398194