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Target Details

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Name:Cytochrome P450 2C18
Uniprot name:CP2CI_HUMAN
Accession Numbers:B2R8K2 P33260 Q16703 Q16751 Q6GRG1
EC-Number:1.14.14.1
Organism:Homo sapiens
Human
PDB IDs:2H6P
KEGG Pathways:show KEGG Pathways
Drugs:
NamePubChem IDSourceReferencesInteraction
BUPRENORPHINE40400SuperCypPMID 15743975show
Buprenorphine5311033SuperCypPMID 15743975show
CHEMBL12018310861208BindingDB-show
CHEMBL12042610938696BindingDB-show
CHEMBL12079710894740BindingDB-show
CHEMBL12082510861641BindingDB-show
CHEMBL12104044346781BindingDB-show
CHEMBL12104811123454BindingDB-show
CHEMBL12124111732429BindingDB-show
CHEMBL12132311100382BindingDB-show
CHEMBL12142011103028BindingDB-show
CHEMBL12150310950401BindingDB-show
CHEMBL12152211070834BindingDB-show
CHEMBL33087111078396BindingDB-show
CHEMBL33143111133137BindingDB-show
CHEMBL33148511046887BindingDB-show
CHEMBL33269010895263BindingDB-show
CHEMBL33299411013215BindingDB-show
CHEMBL33310810916150BindingDB-show
CHEMBL33321010938153BindingDB-show
CHEMBL33370410948187BindingDB-show
CHEMBL41423810045582BindingDB-show
CHEMBL43238610245060BindingDB-show
CHEMBL44354210925491BindingDB-show
Chlorepin2789SuperCypPMID 15483195show
Chlorperphenazine4748SuperCypPMID 11136295show
CLOTIAZEPAM2811SuperCypPMID 16141545show
Cyclophosphoramide2907SuperCypPMID 10348794show
dexlansoprazole3883PROMISCUOUSPMID 12612455show
dexlansoprazole3883SuperCypPMID 7870052show
Dextromethadone4095SuperCypPMID 8839037show
Dextromethadone643985SuperCypPMID 8839037show
Diaminodiphenylsulfone2955SuperCypPMID 10901692show
Dichlofenac3033PROMISCUOUS3 PMIDsshow
Dichlofenac3033SuperCyp2 PMIDsshow
Diethylparaoxon9395SuperTarget-show
Diisopropylphenol4943PROMISCUOUSPMID 9764927show
Diisopropylphenol4943SuperCypPMID 9771309show
Dimethylaminophenyldimethylpyrazolone6009PROMISCUOUSPMID 11853173show
Dimethylaminophenyldimethylpyrazolone6009SuperCypPMID 10199594show
Dimethyloxyquinazine2206SuperCypPMID 8681486show
Diphenylhydatanoin1775PROMISCUOUS2 PMIDsshow
Diphenylhydatanoin1775SuperCypPMID 11996015show
Dipropylacetate3121SuperCypPMID 9606477show
DMZ447297BindingDB-show
Esomeprazole4594SuperCypPMID 8894508show
Isophosphamide3690SuperCypPMID 10348794show
Lidocaine Monohydrochloride3676PROMISCUOUSPMID 15845683show
Lidocaine Monohydrochloride3676SuperCyp2 PMIDsshow
Methylaminopropyliminodibenzyl2995SuperCypPMID 9884317show
Methyldiazepinone3016SuperCypPMID 9028867show
Norchlorimipramine3696SuperCypPMID 9190854show
Rattentraenke6691SuperCypPMID 7704034show
Sulfaphenylpyrazole5335BindingDB-show
Tolylsulfonylbutylurea5505PROMISCUOUSPMID 14973304show
Tolylsulfonylbutylurea5505SuperCypPMID 11996015show
Triacetyloleandomycin202225PROMISCUOUS4 PMIDsshow
Triacetyloleandomycin202225SuperCypPMID 15054565show
Trichloraethylenum6575SuperTarget-show
Synonyms:
CYPIIC18
Cytochrome P450 2C18
P450-6B/29C
Similar targets:
Uniprot name% Sequence similarity% Sequence identity
CP2CJ_HUMAN91.881
Q5VX92_HUMAN91.681.8
CP2C9_HUMAN91.681.8
CP2C5_RABIT88.677.3
CP2C6_RAT88.477.1
CP2C8_HUMAN87.677.1
CP2CB_RAT86.475.6
CP2E1_HUMAN74.356.5
Q3YA63_HUMAN74.356.5
Q6NWT7_HUMAN74.156.3
Q6NWT9_HUMAN73.956.1
CP2B4_RABIT70.750.1
CP2B1_RAT70.751.1
CP2F1_HUMAN70.551.3
CP2B6_HUMAN6947.9
CP2A6_HUMAN68.948.7
CP2AD_HUMAN68.449.3
CP2A7_HUMAN68.247.7
CP2A5_MOUSE68.249.5
Q16743_HUMAN65.558.6
CP2S1_HUMAN61.542.3
CP2D1_RAT58.139
CP2W1_HUMAN58.138
Q6NWU0_HUMAN5838.6
CP2D6_HUMAN5838.6
Q38LG0_HUMAN57.838.4
Q38LG2_HUMAN57.838.2
CP2J2_HUMAN56.937.2
Q6XP50_HUMAN54.436.1
Q14097_HUMAN52.736.9
Protein-Protein Interactions:
No data available