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Target Details

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Name:CYPIIB6
Uniprot name:CP2B6_HUMAN
Accession Numbers:P20813 Q2V565 Q9UK46
EC-Number:1.14.14.1
Organism:Homo sapiens
Human
PDB IDs:-
KEGG Pathways:show KEGG Pathways
Drugs:
NamePubChem IDSourceReferencesInteraction
(1E,4Z,6E)-5-hydroxy-1,7-bis(4-hydroxy-3-methoxyphenyl)hepta-1,4,6-trien-35281767BindingDB-show
(NE)-N-[(5-pyridin-3-yl-2-furyl)methylidene]hydroxylamine11389855BindingDB-show
(NE)-N-[(5-pyridin-3-yl-2-furyl)methylidene]hydroxylamine11355925BindingDB-show
(NZ)-N-[(5-pyridin-3-ylthiophen-2-yl)methylidene]hydroxylamine11264173BindingDB-show
3,3'-Bipyridine68487BindingDB-show
3-(1H-Imidazol-4-yl)pyridine3040177BindingDB-show
3-(3-Thienyl)pyridine595254BindingDB-show
Adriablastin31703SuperCyp-show
Aethinyloestradiolum5991SuperCyp2 PMIDsshow
AI-942/25034651595145BindingDB-show
Alitretinoin444795SuperCyp-show
ALITRETINOIN449171SuperCyp-show
Allylisopropylmalonylurea6464SuperCypPMID 8313534show
Amfebutamone444SuperCyp8 PMIDsshow
Amitriprolidine2160SuperCypPMID 11259560show
Amlodipine Benzenesulfonate2162SuperCypPMID 10805063show
Amprenavir65016PROMISCUOUS2 PMIDsshow
Amprenavir65016SuperCypPMID 11159797show
Androsteston5995SuperCyp4 PMIDsshow
Azelastine2267SuperCyp-show
Bromochlorotrifluoroethane3562SuperCypPMID 14515060show
Carbamazepine2554SuperCypPMID 14977870show
CHEBI:4180411332763BindingDB-show
CHEMBL109135646866604BindingDB-show
CHEMBL125851746947264BindingDB-show
CHEMBL128905325057124BindingDB-show
CHEMBL128928324857598BindingDB-show
CHEMBL128939550908737BindingDB-show
CHEMBL128939652941699BindingDB-show
CHEMBL128951525054288BindingDB-show
CHEMBL129004125205318BindingDB-show
CHEMBL129015025205319BindingDB-show
CHEMBL129015552942456BindingDB-show
CHEMBL129026444194849BindingDB-show
CHEMBL17868144388657BindingDB-show
CHEMBL17871111210706BindingDB-show
CHEMBL17878011207072BindingDB-show
CHEMBL17878144388612BindingDB-show
CHEMBL17900511389737BindingDB-show
CHEMBL17939810899427BindingDB-show
CHEMBL17939944388606BindingDB-show
CHEMBL17952944388719BindingDB-show
CHEMBL17966923646069BindingDB-show
CHEMBL17970411378800BindingDB-show
CHEMBL20783111612187BindingDB-show
CHEMBL20852811641076BindingDB-show
CHEMBL24298316745311BindingDB-show
CHEMBL24423916072099BindingDB-show
CHEMBL26621244428924BindingDB-show
CHEMBL35965711206290BindingDB-show
CHEMBL36099911344157BindingDB-show
CHEMBL36136411480732BindingDB-show
CHEMBL36270215778480BindingDB-show
CHEMBL36888316654686BindingDB-show
CHEMBL40703410829689BindingDB-show
CHEMBL42551911389927BindingDB-show
CHEMBL44608325180109BindingDB-show
CHEMBL44759124827305BindingDB-show
CHEMBL44874318407230BindingDB-show
CHEMBL45316925034431BindingDB-show
CHEMBL45639025147692BindingDB-show
CHEMBL46017825180304BindingDB-show
CHEMBL46209325180108BindingDB-show
CHEMBL49837110647667BindingDB-show
CHEMBL49900725180500BindingDB-show
CHEMBL50039424754344BindingDB-show
CHEMBL50282425034348BindingDB-show
CHEMBL6281113728862BindingDB-show
Chlorepin2789SuperCypPMID 15483195show
Chlormethiazole10783SuperCypPMID 11996015show
Chlorperphenazine4748SuperCyp-show
Chlotrimazole2812SuperCypPMID 14977870show
Cholecalciferol6221SuperCypPMID 10219964show
CID 1021827811238080BindingDB-show
Cinnarizine2761SuperCypPMID 8951176show
Citalopram Hydrobromide2771SuperCyp-show
Clonazepamum2802SuperCypPMID 9193878show
CLOTIAZEPAM2811SuperCypPMID 16141545show
Cloxifenolum5564SuperCypPMID 8696774show
Colchicinum6167SuperCypPMID 12815172show
Conquinine5953SuperCypPMID 8886607show
cyanoguanidine, 344249821BindingDB-show
Cyclophosphoramide2907SuperCyp6 PMIDsshow
Desoxyphenobarbitone4909SuperCyp-show
Dextromethadone4095SuperCyp3 PMIDsshow
Dextromethadone643985SuperCyp3 PMIDsshow
DEXTROMETHORPHAN5360696SuperCypPMID 10760842show
Dichlofenac3033PROMISCUOUS3 PMIDsshow
Dichlofenac3033SuperCypPMID 10449188show
diethylcarbamothioylsulfanyl diethylaminomethanedithioate3117SuperCyp-show
Diethylparaoxon9395SuperTarget-show
Diethyltoluamide4284SuperCypPMID 11854147show
Diisopropylphenol4943PROMISCUOUSPMID 9764927show
Diisopropylphenol4943SuperCyp5 PMIDsshow
Dimethyloxyquinazine2206SuperCyp2 PMIDsshow
Diphenylhydatanoin1775PROMISCUOUS2 PMIDsshow
Diphenylhydatanoin1775SuperCyp4 PMIDsshow
DL-tetrahydronicotyrine942SuperCyp3 PMIDsshow
Domperidone Monohydrochloride3151SuperCypPMID 15327587show
Efavirenz64139SuperCyp7 PMIDsshow
EFAVIRENZ3203SuperCyp7 PMIDsshow
Enteropride2769SuperCypPMID 10859153show
Epinastine3241SuperCypPMID 9485522show
Erythromycin ethylsuccinate12560SuperCyp-show
Ethyl chlorophenoxyisobutyrate2796SuperCypPMID 7587930show
Ethylmorphine5359271SuperCypPMID 9633999show
Flunitrazepam3380SuperCypPMID 11159802show
Fluormethylprednisolone5743SuperCypPMID 11286621show
fluoromethyl hexafluoroisopropyl ether5206SuperCyp2 PMIDsshow
Fluoxetine Hydrochloride3386SuperCypPMID 10997938show
Fluvoxamine3404PROMISCUOUS7 PMIDsshow
Fluvoxamine5361192PROMISCUOUS7 PMIDsshow
Fluvoxamine3404SuperCypPMID 10997936show
Fluvoxamine5361192SuperCypPMID 10997936show
Fosphenytoin56339SuperCyp-show
Go-Y02610691533BindingDB-show
GW-34309826520BindingDB-show
Huanghuahaosu68827SuperCyp4 PMIDsshow
Hydroxydiazepam5391SuperCypPMID 8948091show
Hydroxymethoxybenzyl pelargonamide2998SuperCypPMID 12641434show
Iproveratril2520SuperCyp3 PMIDsshow
irinotecan hydrochloride60838SuperCyp-show
Irinotecan hydrochloride74990SuperCyp-show
Isoflurane3763SuperCypPMID 7720526show
ISOFLURANE4369440SuperCypPMID 7720526show
Isonipecaine4058SuperCypPMID 15319333show
Isophosphamide3690SuperCyp4 PMIDsshow
Isopromethazine4927PROMISCUOUSPMID 11936702show
Isopromethazine4927SuperCypPMID 14515060show
Ketamine3821SuperCyp2 PMIDsshow
Ketobemidonum10101SuperCypPMID 16278191show
KETOCONAZOLE47576SuperCypPMID 14709627show
Ketoconazole3823SuperCypPMID 14709627show
Ketoconazole456201SuperCypPMID 14709627show
Ketohydroxyoestrin5870SuperCyp3 PMIDsshow
Lidocaine Monohydrochloride3676PROMISCUOUSPMID 15845683show
Lidocaine Monohydrochloride3676SuperCypPMID 8866826show
Loperamide Monohydrochloride3955SuperCyp2 PMIDsshow
Lopinavir92727PROMISCUOUSPMID 10421617show
Lopinavir92727SuperCypPMID 12724045show
MEMANTINE HYDROCHLORIDE4054SuperCypPMID 15378224show
Methoxifluranum4116SuperCypPMID 7879937show
Methylaminophenyldimethylpyrazolone methanesulfonate sodium522325SuperCypPMID 17344806show
Methylaminopropyliminodibenzyl2995SuperCyp-show
Methylcarbinol702SuperCypPMID 9929510show
Methyldiazepinone3016SuperCyp2 PMIDsshow
Methyldiphenylhydramine4601SuperCyp3 PMIDsshow
Methylmercaptoimidazole1349907SuperCypPMID 9172960show
Methylphenobarbitonum8271SuperCypPMID 15284537show
Methyltestosterone6010SuperCypPMID 10630892show
Mexiletene hydrochloride4178SuperCypPMID 12519691show
Mianserin Monohydrochloride4184SuperCyp2 PMIDsshow
Miconazole4189SuperCypPMID 11854151show
Midazolam hydrochloride4192PROMISCUOUSPMID 16472102show
MIDAZOLAM HYDROCHLORIDE43032PROMISCUOUSPMID 16472102show
Midazolam hydrochloride4192SuperCypPMID 9732386show
MIDAZOLAM HYDROCHLORIDE43032SuperCypPMID 9732386show
MODAFINIL4236SuperCyp2 PMIDsshow
Nelfinavir64143PROMISCUOUSPMID 16433896show
Nelfinavir64143SuperCypPMID 11159797show
Nevirapine4463SuperCyp4 PMIDsshow
Nicardipine hydrochloride4474PROMISCUOUSPMID 15377640show
Nicardipine hydrochloride4474SuperCypPMID 11560876show
Nifedipine Monohydrochloride4485SuperCypPMID 11560876show
Norchlorimipramine3696SuperCypPMID 9190854show
NSC7055912407524BindingDB-show
Oleophosphothion4004SuperCypPMID 15557345show
Parabromdylamine6834SuperCyp-show
Paracarbinoxamine2564SuperCyp-show
Paroxetine43815SuperCypPMID 10997936show
Perhexilline4746SuperCypPMID 17050648show
Permethrine40463SuperCypPMID 17936932show
Phenylaethylbarbitursaeure4763SuperCyp7 PMIDsshow
Retinol1071SuperCypPMID 10219964show
Rifampicinum5381226SuperCyp2 PMIDsshow
Ritonavir392622BindingDB-show
Ritonavir392622PROMISCUOUS2 PMIDsshow
Ritonavir392622SuperCyp2 PMIDsshow
ROPIVACAINE HYDROCHLORIDE MONOHYDRATE71273SuperCyp3 PMIDsshow
Roxithromycin444037PROMISCUOUSPMID 9806945show
Roxithromycin444037SuperCypPMID 17164692show
Selegiline hydrochloride26757SuperCyp3 PMIDsshow
Sertraline Hydrochloride68617SuperCyp2 PMIDsshow
Sertraline hydrochloride63009SuperCyp2 PMIDsshow
Sulconazole5318SuperCypPMID 11854151show
Sulfaphenylpyrazole5335PROMISCUOUS6 PMIDsshow
Sulfaphenylpyrazole5335SuperCypPMID 8886607show
Sulfoxyphenylpyrazolidine5342SuperCypPMID 14977870show
tariquidarth148201BindingDB-show
Tetramethylthiocarbamoyldisulphide5455SuperCyp-show
TICLOPIDINE HYDROCHLORIDE5472SuperCyp3 PMIDsshow
Ticlopidine hydrochloride65335SuperCyp3 PMIDsshow
Tomaxithen2733526SuperCyp8 PMIDsshow
Tramadol hydrochloride33741SuperCyp2 PMIDsshow
TRAMADOL HYDROCHLORIDE5523SuperCyp2 PMIDsshow
Tramadol hydrochloride63013SuperCyp2 PMIDsshow
tranylcypromine19493BindingDB-show
Trichloraethylenum6575SuperTarget-show
Triethylenethiophosphorotriamide5453PROMISCUOUSPMID 15121764show
Triethylenethiophosphorotriamide5453SuperCyp2 PMIDsshow
Trilophosphamide65702SuperCypPMID 10447581show
TROGLITAZONE5591PROMISCUOUSPMID 15860655show
TROGLITAZONE5591SuperCypPMID 10752642show
VenlafaxineXR5656SuperCyp-show
Zotepine5736SuperCypPMID 10219963show
Synonyms:
CYPIIB6
Cytochrome P450 2B6
P450 IIB1
Similar targets:
Uniprot name% Sequence similarity% Sequence identity
CP2B1_RAT87.675.8
CP2B4_RABIT8777.4
Q14097_HUMAN73.570.1
CP2AD_HUMAN71.752.8
CP2A5_MOUSE71.552.2
CP2A6_HUMAN71.351.6
CP2A7_HUMAN71.351.8
Q5VX92_HUMAN69.748.5
CP2C9_HUMAN69.748.5
CP2CI_HUMAN6947.9
CP2C5_RABIT6949.1
CP2C8_HUMAN68.850.3
CP2CJ_HUMAN68.248.1
CP2C6_RAT6847
CP2F1_HUMAN67.848.2
CP2CB_RAT67.349.9
CP2E1_HUMAN66.845.6
Q3YA63_HUMAN66.845.6
Q6NWT7_HUMAN66.845.6
CP2S1_HUMAN66.647.4
Q6NWT9_HUMAN66.445.6
CP2D1_RAT57.838.4
CP2J2_HUMAN57.740
CP2W1_HUMAN56.138.2
CP2D6_HUMAN5640.3
Q6NWU0_HUMAN5640.3
Q38LG0_HUMAN55.840.1
Q38LG2_HUMAN55.439.7
Q6XP50_HUMAN54.738.4
CP2R1_HUMAN53.734.7
Protein-Protein Interactions:
No data available