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Target Details

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Name:CYPIA1
Uniprot name:CP1A1_HUMAN
Accession Numbers:P04798 Q53G18
EC-Number:1.14.14.1
Organism:Homo sapiens
Human
PDB IDs:-
KEGG Pathways:show KEGG Pathways
Drugs:
NamePubChem IDSourceReferencesInteraction
1-Methoxyrutaecarpine5319487BindingDB-show
1-[(Z)-2-(3,5-dimethoxyphenyl)ethenyl]-3,5-dimethoxy-benzene9817804BindingDB-show
2-prop-1-ynylphenanthrene10059170BindingDB-show
3,4',5-trimethoxy-trans-stilbene5388063BindingDB-show
4'-O-Methylisoflavone439901BindingDB-show
4-(4-Hydroxyanilino)-4-oxobutanoic acid605610BindingDB-show
6-fluoro-3-(4-methoxyphenyl)chromen-4-one2778583BindingDB-show
6-Methyl-1,3,8-trichlorodibenzofuran114900PROMISCUOUS2 PMIDsshow
7,8-Benzoflavone11790BindingDB-show
7,8-Dehydrorutaecarpine148756BindingDB-show
AC1L4G2I156372BindingDB-show
AC1MR5D33512637BindingDB-show
Acetyladriamycin30323SuperCypPMID 15588138show
Acocantherin12420SuperCypPMID 12187936show
Aethinyloestradiolum5991SuperCypPMID 15304426show
Albendazole Monohydrochloride2082SuperCyp2 PMIDsshow
AMINOFLAVONE389710PROMISCUOUSPMID 18059023show
Amiodarone Hydrochloride2157SuperCypPMID 11038157show
AMIODARONE HYDROCHLORIDE441325SuperCypPMID 11038157show
Amlodipine Benzenesulfonate2162SuperCypPMID 10805063show
Amodiachinum2165SuperCypPMID 11805197show
Androsteston5995SuperCypPMID 10975606show
Apigenine5280443BindingDB-show
Ardeytropin6305SuperCypPMID 17020875show
Arthrocine1548887SuperCypPMID 16531450show
Benoxaprofen39941SuperCypPMID 2069584show
Benzpyrene2336PROMISCUOUS2 PMIDsshow
Benzydamine Monohydrochoride12555SuperCypPMID 11012553show
beta-Methylindole6736PROMISCUOUSPMID 17962375show
Bortezomib93860SuperCyp-show
Bortezomib387447SuperCyp-show
Buddleoflavonol5280442BindingDB-show
CHEMBL12253244347296BindingDB-show
CHEMBL21155911565664BindingDB-show
CHEMBL21268916007088BindingDB-show
CHEMBL31224811109908BindingDB-show
CHEMBL31284844318917BindingDB-show
CHEMBL31444544319159BindingDB-show
CHEMBL31542215559184BindingDB-show
CHEMBL37783211507689BindingDB-show
CHEMBL424289834747BindingDB-show
CHEMBL4301311957947BindingDB-show
CHEMBL4339511066044BindingDB-show
CHEMBL4339610105252BindingDB-show
CHEMBL4374011808336BindingDB-show
CHEMBL437419818893BindingDB-show
CHEMBL4415611055725BindingDB-show
CHEMBL52922024796588BindingDB-show
CHEMBL851069973392BindingDB-show
CHEMBL8574044319169BindingDB-show
CHEMBL8596015549947BindingDB-show
CHEMBL8602244319156BindingDB-show
CHEMBL8607810426244BindingDB-show
Chloroquinium2719SuperCypPMID 12756207show
Chlorothiazide2720SuperCypPMID 11684361show
Chlorzoxazone2733SuperTargetPMID 009531516show
Cholecalciferol6221SuperCypPMID 10219964show
Chromoflavine6842SuperCypPMID 12065765show
Chrysoeriol5280666BindingDB-show
Cinnarizine2761SuperCypPMID 8951176show
Cisclomiphene1548955SuperCypPMID 9054622show
Clobetasol32798SuperCypPMID 16882163show
Clobetasol32797SuperCypPMID 16882163show
Cloxifenolum5564SuperCypPMID 8696774show
Clozapine2818SuperCypPMID 10422890show
Colchicinum6167SuperCypPMID 16611024show
Conquinine5953SuperCypPMID 11765139show
Contraspasmin2783SuperCypPMID 15710352show
Dantrolene2952SuperCypPMID 7902259show
Debrisochinum2966SuperCypPMID 12023534show
Debrisochinum2966SuperTargetPMID 012642457show
Dehydroepiandrosterone5881SuperCyp3 PMIDsshow
Deltamethrine40585SuperCypPMID 16169030show
DESFERRIOXAMINE2973SuperCypPMID 10799651show
desmethylxanthohumol639665PROMISCUOUSPMID 10752639show
dexlansoprazole3883PROMISCUOUSPMID 12612455show
dexlansoprazole3883SuperCyp2 PMIDsshow
Dexpropranolol4946SuperCypPMID 8474022show
dexrabeprazole5029PROMISCUOUS3 PMIDsshow
dexrabeprazole5029SuperCypPMID 12623754show
Diaethylstilboestrolum448537SuperCypPMID 17129689show
Dichlofenac3033PROMISCUOUS3 PMIDsshow
Dichlofenac3033SuperCypPMID 10572000show
Diethylaminocarbethoxybicyclohexyl hydrochloride3042SuperCypPMID 9661887show
Diethylparaoxon9395SuperTarget-show
Digitoflavone5280445BindingDB-show
Dihydrochrysin68071BindingDB-show
Dihydrofolliculin5757SuperCyp5 PMIDsshow
Dihydroxyphenylethanolisopropylamine3779SuperCypPMID 15627480show
Diisopropylphenol4943PROMISCUOUSPMID 9764927show
Diisopropylphenol4943SuperCypPMID 7772432show
Dimethoxydiphenyltrichloroethane4115PROMISCUOUSPMID 8114062show
Dimethylbenzanthracene6001PROMISCUOUSPMID 10496959show
Dimethylchrysin88881PROMISCUOUSPMID 15661813show
Dimethyltriazenoimidazolecarboxamide5351166SuperCypPMID 10473105show
Diosmetin5281612BindingDB-show
Diosmetin5281612SuperCyp2 PMIDsshow
Diosmin5281613SuperCypPMID 9661887show
DL-tetrahydronicotyrine942SuperCyp3 PMIDsshow
Enilconazole37175PROMISCUOUSPMID 19070657show
Enoxacin Sesquihydrate3229SuperCypPMID 7503804show
Ergostetrine443884SuperCypPMID 12583687show
ERIODICTYOL440735BindingDB-show
Esomeprazole4594SuperCyp8 PMIDsshow
Ethyl chlorophenoxyisobutyrate2796SuperCyp2 PMIDsshow
Evodiamine151289BindingDB-show
Floropipamide4830SuperCypPMID 9233375show
fluindostatin446155PROMISCUOUSPMID 10952477show
Fluindostatin1548972PROMISCUOUSPMID 10952477show
fluindostatin446155SuperCyp2 PMIDsshow
Fluindostatin1548972SuperCyp2 PMIDsshow
flunarizine dihydrochloride941361SuperCypPMID 8951176show
FLUNARIZINE DIHYDROCHLORIDE6365505SuperCypPMID 8951176show
Fluormethylprednisolone5743SuperCyp2 PMIDsshow
Fluvoxamine3404PROMISCUOUS7 PMIDsshow
Fluvoxamine5361192PROMISCUOUS7 PMIDsshow
Fluvoxamine3404SuperCyp3 PMIDsshow
Fluvoxamine5361192SuperCyp3 PMIDsshow
Galangin flavanone5281607BindingDB-show
Gelbkoerperhormon5994SuperCyp2 PMIDsshow
Granisetron Monohydrochloride3510SuperCypPMID 16248838show
Guanamprazine16231SuperCypPMID 15081870show
Haloperidol3559SuperCypPMID 11717183show
Herbimycin5311102PROMISCUOUSPMID 9784250show
Herbimycin6436247PROMISCUOUSPMID 9784250show
Hesperetin72281BindingDB-show
Hexachlorocyclohexanes727SuperCypPMID 11684361show
Homoeriodictyol73635BindingDB-show
Hydrargyrum23931SuperCypPMID 12173417show
Hydroxyacetanilide1983BindingDB-show
Hydroxyacetanilide1983SuperCypPMID 8145237show
Hydroxymethoxybenzyl pelargonamide2998SuperCypPMID 12641434show
Indinol3712PROMISCUOUSPMID 8866829show
Intraconazole55283SuperCypPMID 17283379show
Ipriflavone3747SuperCypPMID 16597362show
isorhamnetine5281654BindingDB-show
isorhamnetine5281654PROMISCUOUSPMID 16226778show
Isosakuranetin160481BindingDB-show
Kaempferide5281666BindingDB-show
KETOCONAZOLE47576SuperCyp3 PMIDsshow
Ketoconazole3823SuperCyp3 PMIDsshow
Ketoconazole456201SuperCyp3 PMIDsshow
Ketohydroxyoestrin5870SuperCyp3 PMIDsshow
MEBENDAZOLE4030SuperCypPMID 12841937show
Mecamylamine Hydrochloride4032SuperCypPMID 10594335show
Melatonine896SuperCypPMID 15616152show
Methylarecaidin2230PROMISCUOUSPMID 17707585show
Methylcarbinol702SuperCypPMID 9929510show
Methylnaphthoquinone4055SuperCypPMID 15603920show
Methyltheobromide2519SuperCypPMID 8474022show
Mibefradil60663SuperCypPMID 9211656show
Mitobronitol656655SuperCypPMID 11358806show
Moricizine34633SuperCypPMID 12393941show
Nifedipine Monohydrochloride4485SuperCypPMID 8474022show
Nitroferricyanide11963622SuperCypPMID 8170947show
Nitrofuradantin6604200SuperCyp-show
Nitrofuradantin4509SuperCyp-show
Norfloxacine4539SuperCypPMID 8894516show
Norizalpinin5281616BindingDB-show
NovoFlutamide3397SuperCypPMID 11160641show
NSC6224735387294BindingDB-show
NSC660031378228BindingDB-show
Oxalatoplatinum9887054SuperCypPMID 14646291show
Oxyresveratrol5281717BindingDB-show
Paracetophenetidin4754SuperCyp2 PMIDsshow
Paracetophenetidin4754SuperTarget2 PMIDsshow
Pelargidanon439246BindingDB-show
Pelargidenolon5280863BindingDB-show
Pelargidenolon5280863PROMISCUOUSPMID 16226778show
Pernazine4744PROMISCUOUSPMID 12523495show
Pernazine4744SuperCypPMID 15056479show
Phenylaethylsenfoel16741PROMISCUOUSPMID 17582584show
Primachinum4908SuperCyp2 PMIDsshow
Procarbazine Monohydrochloride4915SuperCypPMID 1316811show
Propylthiouracil657298SuperCypPMID 15183118show
Pseudotheophylline2153SuperCyp2 PMIDsshow
Pterostilbene5320791PROMISCUOUSPMID 17440990show
Pyrazoleanthrone8515PROMISCUOUS3 PMIDsshow
Pyrene[def]phenanthrene31423BindingDB-show
Quinineanhydrous8549SuperCyp2 PMIDsshow
Resorcinolphthalein16850SuperCypPMID 7923575show
Resveratrol445154PROMISCUOUS3 PMIDsshow
Retinol1071SuperCyp2 PMIDsshow
Riboflavinequinone493570SuperCypPMID 9512490show
Riboflavinequinone6759SuperCypPMID 9512490show
Riluzole5070SuperCyp2 PMIDsshow
Rutaecarpine65752BindingDB-show
Salicylamide5147SuperCypPMID 14729655show
Sildenafil5212SuperCyp-show
Sklerofibrat39042SuperCypPMID 15521013show
ST077708378227BindingDB-show
STREPTOZOTOCIN29327SuperCypPMID 15674819show
Streptozotocin5300SuperCypPMID 15674819show
Succinonitrile, bis(amino(o-aminophenylthio)methylene)-3006531PROMISCUOUS2 PMIDsshow
Tamarixetin5281699BindingDB-show
Terazosin hydrochloride4893SuperCypPMID 15627480show
Terazosin hydrochloride5401SuperCypPMID 15627480show
Tetrabenazine6018SuperCypPMID 15603920show
Tetrachlorodibenzodioxin15625PROMISCUOUS2 PMIDsshow
Tetrahydrocannabinols16078SuperCypPMID 15714209show
Tetrahydrocannabinols2977SuperCypPMID 15714209show
Thiabendazolum5430SuperCyp7 PMIDsshow
TICLOPIDINE HYDROCHLORIDE5472SuperCyp-show
Ticlopidine hydrochloride65335SuperCyp-show
TMS cpd5354004BindingDB-show
Tocainide Hydrochloride38945SuperCypPMID 8689940show
Tomaxithen2733526SuperCypPMID 12124303show
Toremifene3005573SuperCypPMID 8204106show
Toremifene3005572SuperCypPMID 8204106show
Trichloraethylenum6575SuperTarget-show
trihydroxidoarsenic545SuperCypPMID 11854143show
TROGLITAZONE5591PROMISCUOUSPMID 15860655show
TROGLITAZONE5591SuperCypPMID 10534310show
Xanthaurine5280343BindingDB-show
Xanthotoxine4114PROMISCUOUSPMID 12814958show
Xanthotoxine4114SuperCypPMID 8474022show
ZINC00545100946468BindingDB-show
ZINC031924992321450BindingDB-show
Zotepine5736SuperCypPMID 10219963show
Synonyms:
CYPIA1
Cytochrome P450 1A1
P450 form 6
P450-C
P450-P1
Similar targets:
Uniprot name% Sequence similarity% Sequence identity
Q53G23_HUMAN99.499
CP1A1_MOUSE88.578.2
CP1A1_RAT8877.7
CP1A2_HUMAN83.671.8
Q6NWU3_HUMAN83.471.6
CP1A2_RABIT81.168
CP1A2_MOUSE80.867.2
CP1A2_RAT80.266.9
CP1A3_ONCMY74.855.8
CP1B1_MOUSE55.237.4
CP1B1_HUMAN54.637.3
CP2F1_HUMAN53.632.2
CP2AD_HUMAN50.730.9
Q6NWT9_HUMAN50.230
CP2E1_HUMAN50.230
Q6NWT7_HUMAN50.230
Q3YA63_HUMAN5029.8
CP2A6_HUMAN49.830.2
CP2A7_HUMAN49.729.9
CP2A5_MOUSE49.630.1
CP2B1_RAT49.430.7
Q5VX92_HUMAN49.329.9
CP2C9_HUMAN49.329.9
CP2CB_RAT49.230.6
CP2J2_HUMAN48.328.5
CP2B6_HUMAN48.229
CP2B4_RABIT48.128.7
CP17A_RAT48.131.1
CP2C5_RABIT4829.1
CP2CI_HUMAN47.929.8
Protein-Protein Interactions: