Home
Drugs
Targets
Pathways
Ontologies
Cyp450s
Adv.search
Help/FAQ

Target Details

add
Name:Cell division protein kinase 7
Uniprot name:CDK7_HUMAN
Accession Numbers:P50613 Q9BS60 Q9UE19
EC-Number:2.7.11.22
2.7.11.23
Organism:Homo sapiens
Human
PDB IDs:1LG3 1PA8 1UA2 2HIC
KEGG Pathways:show KEGG Pathways
Drugs:
NamePubChem IDSourceReferencesInteraction
3-((3R,4R)-4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperi9926791BindingDB-show
3-(Indol-2-yl)indazole 1023646002BindingDB-show
3-(Indol-2-yl)indazole 1123646003BindingDB-show
3-(Indol-2-yl)indazole 1323646005BindingDB-show
3-(Indol-2-yl)indazole 1423646006BindingDB-show
3-(Indol-2-yl)indazole 1523646007BindingDB-show
3-(Indol-2-yl)indazole 1623646008BindingDB-show
3-(Indol-2-yl)indazole 1723646009BindingDB-show
3-(Indol-2-yl)indazole 1823646010BindingDB-show
3-(Indol-2-yl)indazole 1923646011BindingDB-show
3-(Indol-2-yl)indazole 2023646012BindingDB-show
3-(Indol-2-yl)indazole 2116058617BindingDB-show
3-(Indol-2-yl)indazole 2223646013BindingDB-show
3-(Indol-2-yl)indazole 2323646014BindingDB-show
3-(Indol-2-yl)indazole 2411532543BindingDB-show
3-(Indol-2-yl)indazole 623645998BindingDB-show
3-(Indol-2-yl)indazole 723645999BindingDB-show
3-(Indol-2-yl)indazole 823646000BindingDB-show
3-(Indol-2-yl)indazole 923646001BindingDB-show
4-(3,5-Diamino-1H-pyrazol-4-ylazo)-phenol9859248BindingDB-show
ABT-86911485656BindingDB-show
AMG 70611667893BindingDB-show
AST-48711409972BindingDB-show
Canertinib156414BindingDB-show
Cdk2/9 Inhibitor447961BindingDB-show
CHEBI:1043465459219BindingDB-show
CHEBI:25992444329707BindingDB-show
CHEBI:54743644560358BindingDB-show
CHEBI:66834345481533BindingDB-show
CHEBI:66834445481534BindingDB-show
CHEMBL108215211560568BindingDB-show
CHEMBL108315046830766BindingDB-show
CHEMBL108315111632150BindingDB-show
CHEMBL108315211718021BindingDB-show
CHEMBL108348411744184BindingDB-show
CHEMBL108378610024433BindingDB-show
CHEMBL108445446830767BindingDB-show
CHEMBL108462910430000BindingDB-show
CHEMBL108463010340715BindingDB-show
CHEMBL108471511646645BindingDB-show
CHEMBL108496946830768BindingDB-show
CHEMBL108562610248401BindingDB-show
CHEMBL108608811647020BindingDB-show
CHEMBL109440824993189BindingDB-show
CHEMBL1200779797370BindingDB-show
CHEMBL124070352945601BindingDB-show
CHEMBL1913369863538BindingDB-show
CHEMBL21054016037675BindingDB-show
CHEMBL21204944413527BindingDB-show
CHEMBL2144759964499BindingDB-show
CHEMBL21773410214593BindingDB-show
CHEMBL38706811673204BindingDB-show
CHEMBL42469644413509BindingDB-show
CHEMBL42704516037674BindingDB-show
CHEMBL42863910308009BindingDB-show
CHEMBL45260225169529BindingDB-show
CHEMBL48219325190761BindingDB-show
CHEMBL48221125190763BindingDB-show
CHEMBL49656725195254BindingDB-show
CHEMBL51455411612883BindingDB-show
CHIR-2589886808BindingDB-show
CHIR-26511656518BindingDB-show
CK8447962BindingDB-show
CP-7247149874913BindingDB-show
Dasatinib3062316BindingDB-show
Doramapimod156422BindingDB-show
Erlotinib176870BindingDB-show
Flavopiridol hydrochloride5287969DrugBank-show
Gefitinib123631BindingDB-show
GW-258011617559BindingDB-show
Imatinib Methansulfonate5291BindingDB-show
kinase inhibitor-primary targets: CDK2, CDK9, other CDKs24867231BindingDB-show
Kinome_291844444843BindingDB-show
Kinome_6366420138BindingDB-show
Kinome_75610320107BindingDB-show
Lapatinib ditosylate208908BindingDB-show
Lestaurtinib126565BindingDB-show
MLN805411712649BindingDB-show
nchembio.90-comp111715767BindingDB-show
Pazopanib10113978BindingDB-show
PHOSPHONOTHREONINE3246323DrugBank-show
PI-1039884685BindingDB-show
PKC-4129829523BindingDB-show
pyrazolo[1,5-a]-1,3,5-triazine, 7c25190762BindingDB-show
Roscovitine160355BindingDB-show
Ruboxistaurin153999BindingDB-show
RWJ-3872525330790BindingDB-show
S1018_Selleck9977819BindingDB-show
S1147_Selleck16007391BindingDB-show
S1526_Selleck24889392BindingDB-show
SB 2021905353940BindingDB-show
SB-4315424521392BindingDB-show
SNS-0323025986BindingDB-show
sorafenibum216239BindingDB-show
staurosporine451705BindingDB-show
staurosporine44299148BindingDB-show
STK6686205284904BindingDB-show
SU-1481310138259BindingDB-show
Sunitinib5329102BindingDB-show
Tandutinib3038522BindingDB-show
Vandetanib3081361BindingDB-show
Vatalanib151194BindingDB-show
VX-6805494449BindingDB-show
VX-7453038525BindingDB-show
Synonyms:
39 kDa protein kinase
CAK
CAK1
CDK-activating kinase
Cell division protein kinase 7
P39 Mo15
STK1
TFIIH basal transcription factor complex kinase subunit
Similar targets:
Uniprot name% Sequence similarity% Sequence identity
CDK2_HUMAN55.738.5
CDK5_MOUSE5438.4
CDK5_HUMAN5438.4
CDK1_HUMAN53.937.9
C4R3V7_PICPG51.435.4
CDK6_HUMAN51.333.9
A4D1G0_HUMAN51.333.9
CDC2H_PLAFK50.134.9
CDK9_HUMAN48.634
CDK4_RAT48.233.2
CDK4_HUMAN4832.4
O75100_HUMAN4832.8
MK14_HUMAN45.730.5
MK14_MOUSE45.730.5
MK01_RAT45.433.2
MK01_MOUSE45.433.2
Q499G7_HUMAN45.232.8
Q1HBJ4_HUMAN45.233.1
MK01_HUMAN45.233.1
MK12_HUMAN44.729.2
MK03_HUMAN44.130.7
MK03_MOUSE43.830.4
MK03_RAT43.830.4
CSK21_HUMAN43.227.6
CDK15_HUMAN42.929
GSK3B_MOUSE42.229.4
Q5KU03_MOUSE42.229.4
CSK2A_MAIZE42.226.7
CDK8_HUMAN40.129
GSK3B_HUMAN39.927.3
Protein-Protein Interactions:
Uniprot nameSource
XPF_HUMANPMID 15608231
XPC_HUMAN2 PMIDs
XPA_HUMAN3 PMIDs
VDR_HUMAN4 PMIDs
TTF1_HUMAN5 PMIDs
THA_HUMAN6 PMIDs
TFDP1_HUMAN7 PMIDs
TF2H5_HUMAN8 PMIDs
TF2H4_HUMAN9 PMIDs
TF2H3_HUMAN10 PMIDs
TF2H2_HUMAN11 PMIDs
TF2H1_HUMAN12 PMIDs
TF2B_HUMAN13 PMIDs
TF2AA_HUMAN14 PMIDs
TCEA1_HUMAN15 PMIDs
TBP_HUMAN16 PMIDs
TAF9_HUMAN17 PMIDs
TAF7_HUMAN18 PMIDs
TAF6_HUMAN19 PMIDs
TAF5_HUMAN20 PMIDs
TAF4_HUMAN21 PMIDs
TAF4B_HUMAN22 PMIDs
TAF1_HUMAN23 PMIDs
TAF1C_HUMAN24 PMIDs
TAF1B_HUMAN25 PMIDs
TAF1A_HUMAN26 PMIDs
TAF13_HUMAN27 PMIDs
TAF12_HUMAN28 PMIDs
TAF11_HUMAN29 PMIDs
TAF10_HUMAN30 PMIDs
T2FB_HUMAN31 PMIDs
T2FA_HUMAN32 PMIDs
T2EB_HUMAN33 PMIDs
T2EA_HUMAN34 PMIDs
T2AG_HUMAN35 PMIDs
SYF1_HUMAN36 PMIDs
SSRP1_HUMAN37 PMIDs
SPT5H_HUMAN38 PMIDs
SPT4H_HUMAN39 PMIDs
SP16H_HUMAN40 PMIDs
RRN3_HUMAN41 PMIDs
RPB9_HUMAN42 PMIDs
RPB7_HUMAN43 PMIDs
RPB4_HUMAN44 PMIDs
RPB3_HUMAN45 PMIDs
RPB2_HUMAN46 PMIDs
RPB1_HUMAN47 PMIDs
RPB11_HUMAN48 PMIDs
RPAC2_HUMAN49 PMIDs
RPAC1_HUMAN50 PMIDs
RPAB5_HUMAN51 PMIDs
RPAB4_HUMAN52 PMIDs
RPAB3_HUMAN53 PMIDs
RPAB2_HUMAN54 PMIDs
RPAB1_HUMAN55 PMIDs
RPA2_HUMAN56 PMIDs
RPA1_HUMAN57 PMIDs
RFC5_HUMAN58 PMIDs
RFC4_HUMAN59 PMIDs
RFC3_HUMAN60 PMIDs
RFC2_HUMAN61 PMIDs
RFC1_HUMAN62 PMIDs
RFA3_HUMAN63 PMIDs
RFA2_HUMAN64 PMIDs
RFA1_HUMAN65 PMIDs
RD23B_HUMAN66 PMIDs
RB_HUMAN67 PMIDs
RARA_HUMAN68 PMIDs
Q6IAW3_HUMAN69 PMIDs
PTRF_HUMAN70 PMIDs
PCNA_HUMAN71 PMIDs
PCGF6_HUMAN72 PMIDs
P53_HUMAN73 PMIDs
NELFE_HUMAN74 PMIDs
NELFD_HUMAN75 PMIDs
NELFB_HUMAN76 PMIDs
NELFA_HUMAN77 PMIDs
NEK6_HUMAN78 PMIDs
NCBP2_HUMAN79 PMIDs
NCBP1_HUMAN80 PMIDs
MTA1_HUMAN81 PMIDs
MED21_HUMAN82 PMIDs
MCM7_HUMAN83 PMIDs
MCES_HUMAN84 PMIDs
MCE1_HUMAN85 PMIDs
LASP1_HUMAN86 PMIDs
HNRPU_HUMAN87 PMIDs
HDAC2_HUMAN88 PMIDs
ESR1_HUMAN89 PMIDs
ERCC8_HUMAN90 PMIDs
ERCC6_HUMAN91 PMIDs
ERCC5_HUMAN92 PMIDs
ERCC3_HUMAN93 PMIDs
ERCC3_HUMAN94 PMIDs
ERCC2_HUMAN95 PMIDs
ERCC2_HUMAN96 PMIDs
ERCC1_HUMAN97 PMIDs
ELOC_HUMAN98 PMIDs
ELOB_HUMAN99 PMIDs
ELOA1_HUMAN100 PMIDs
ELL_HUMAN101 PMIDs
E2F5_HUMAN102 PMIDs
E2F4_HUMAN103 PMIDs
E2F3_HUMAN104 PMIDs
E2F2_HUMAN105 PMIDs
E2F1_HUMAN106 PMIDs
DPOE2_HUMAN107 PMIDs
DPOE1_HUMAN108 PMIDs
DPOD4_HUMAN109 PMIDs
DPOD3_HUMAN110 PMIDs
DPOD2_HUMAN111 PMIDs
DPOD1_HUMAN112 PMIDs
DDB2_HUMAN113 PMIDs
DDB1_HUMAN114 PMIDs
CTDP1_HUMAN115 PMIDs
CDK9_HUMAN116 PMIDs
CDK7_HUMAN117 PMIDs
CDK6_HUMAN118 PMIDs
CDK4_HUMAN119 PMIDs
CDC37_HUMAN120 PMIDs
CDC2_HUMAN121 PMIDs
CD2L6_HUMAN122 PMIDs
CD2L1_HUMAN123 PMIDs
CCNT2_HUMAN124 PMIDs
CCNT1_HUMAN125 PMIDs
CCNH_HUMAN126 PMIDs
CCNH_HUMAN127 PMIDs
CCNH_HUMAN128 PMIDs
CCNE2_HUMAN129 PMIDs
CCNE1_HUMAN130 PMIDs
CCND1_HUMAN131 PMIDs
CCNB1_HUMAN132 PMIDs
CASP_HUMAN133 PMIDs
BRCA1_HUMAN134 PMIDs
ANXA2_HUMAN135 PMIDs
ANDR_HUMAN136 PMIDs