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Target Details

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Name:CA-IV
Uniprot name:CAH4_HUMAN
Accession Numbers:P22748
EC-Number:4.2.1.1
Organism:Homo sapiens
Human
PDB IDs:1ZNC 3F7B 3F7U
KEGG Pathways:show KEGG Pathways
Drugs:
NamePubChem IDSourceReferencesInteraction
(1E,4Z,6E)-5-hydroxy-1,7-bis(4-hydroxy-3-methoxyphenyl)hepta-1,4,6-trien-35281767BindingDB-show
1-(3,4-Dichlorophenyl)-3-hydroxyurea97463BindingDB-show
1-Naphthylacetylspermine129695BindingDB-show
1-sulfamoyloxyoctane11117301BindingDB-show
2,4-Disulfamyl-5-trifluoromethylaniline69561BindingDB-show
2,5-Difluorophenol94952BindingDB-show
2-(3-methoxyphenyl)-3-(morpholin-4-ylmethyl)-1,1-dioxothieno[4,5-e]thiazine-6-sulfonamide4369171BindingDB-show
2H-Thieno[3,2-e]-1,2-thiazine-6-sulfonamide 1,1-dioxide 1819434092BindingDB-show
2H-Thieno[3,2-e]-1,2-thiazine-6-sulfonamide 1,1-dioxide 2023645556BindingDB-show
2H-Thieno[3,2-e]-1,2-thiazine-6-sulfonamide 1,1-dioxide 2119434082BindingDB-show
2H-Thieno[3,2-e]-1,2-thiazine-6-sulfonamide 1,1-dioxide 2319434116BindingDB-show
2H-Thieno[3,2-e]-1,2-thiazine-6-sulfonamide 1,1-dioxide 2619434022BindingDB-show
2H-Thieno[3,2-e]-1,2-thiazine-6-sulfonamide 1,1-dioxide 2923645563BindingDB-show
2H-Thieno[3,2-e]-1,2-thiazine-6-sulfonamide 1,1-dioxide 3019434011BindingDB-show
2H-Thieno[3,2-e]-1,2-thiazine-6-sulfonamide 1,1-dioxide 3319434108BindingDB-show
2H-Thieno[3,2-e]-1,2-thiazine-6-sulfonamide 1,1-dioxide 419434096BindingDB-show
2H-Thieno[3,2-e]-1,2-thiazine-6-sulfonamide 1,1-dioxide 619434033BindingDB-show
2H-Thieno[3,2-e]-1,2-thiazine-6-sulfonamide 1,1-dioxide 923645550BindingDB-show
3,5-Difluorophenol75928BindingDB-show
3-AMINOBENZENESULFONAMIDE7377BindingDB-show
3-Carboxycoumarin10752BindingDB-show
3-Fluorosulfanilamide4687472BindingDB-show
3dd811245700BindingDB-show
4-(2-Aminoethyl)benzenesulfonamide169682BindingDB-show
4-amino-3-bromobenzenesulfonamide3526523BindingDB-show
4-Amino-3-chlorobenzenesulfonamide1502014BindingDB-show
4-hydrazinobenzenesulfonamide78105BindingDB-show
4-[[(4-aminophenyl)sulfonylamino]methyl]benzenesulfonamide4422372BindingDB-show
4443145844431458BindingDB-show
5-imino-4-methyl-1,3,4-thiadiazole-2-sulfonamide5172475BindingDB-show
6-Hydroxyethoxyzolamide94706BindingDB-show
667-COUMATE5287541BindingDB-show
8-Methoxy-2-oxo-2H-chromene-3-carboxylic acid234562BindingDB-show
AC1L42WO177700BindingDB-show
AC1LUIIJ1631814BindingDB-show
AC1MO9IB3365615BindingDB-show
AC1MSZXI3542746BindingDB-show
AC1MTMTL3627258BindingDB-show
AC1NNKC65071527BindingDB-show
AC1NQAGI5172319BindingDB-show
AC1NQRR85227639BindingDB-show
Acetamidothiadiazolesulfonamide1986BindingDB-show
Acetamidothiadiazolesulfonamide1986SuperTargetPMID 008056514show
AG444201383BindingDB-show
AG544201382BindingDB-show
AL-66194369172BindingDB-show
aliphatic sulfamate, 219772348BindingDB-show
amidohydroxidodioxidosulfur5987BindingDB-show
aminobenzolamide 1811069133BindingDB-show
Aminoethylethandiamine8111BindingDB-show
Aminozolamide93505BindingDB-show
anglesite1117BindingDB-show
aromatic/heteroaromatic sulfonamide 109861037BindingDB-show
aromatic/heteroaromatic sulfonamide 196852129BindingDB-show
Azide ion33558BindingDB-show
Benzamsulfonamide3998BindingDB-show
Benzohydroquinone785BindingDB-show
Benzothiazide2343DrugBank-show
Benzylhydroflumethiazide2315DrugBank-show
Benzylhydroflumethiazide2315SuperTarget-show
bis-sulfamate, 320043772BindingDB-show
Bismuthate82993BindingDB-show
Bisulfite104748BindingDB-show
Brinzolamide68844BindingDB-show
BRN 017238625090BindingDB-show
Bromate84979BindingDB-show
Bumethanide2471BindingDB-show
caffeic acid689043BindingDB-show
CARBAMYL PHOSPHATE278BindingDB-show
Carbonate19660BindingDB-show
Celecoxib2662BindingDB-show
CHEBI:12957321252335BindingDB-show
CHEBI:3011861441BindingDB-show
CHEBI:3011961857BindingDB-show
CHEBI:302019886BindingDB-show
CHEBI:3094626288BindingDB-show
CHEBI:3928816682992BindingDB-show
CHEBI:40429744391604BindingDB-show
CHEBI:40557944392438BindingDB-show
CHEBI:4650224465BindingDB-show
CHEBI:5351015107BindingDB-show
CHEBI:69777146229200BindingDB-show
CHEMBL108670346887974BindingDB-show
CHEMBL108683446888093BindingDB-show
CHEMBL109520346888059BindingDB-show
CHEMBL109520446888060BindingDB-show
CHEMBL109553146888094BindingDB-show
CHEMBL109585546888136BindingDB-show
CHEMBL109585646888137BindingDB-show
CHEMBL109588246888138BindingDB-show
CHEMBL109588346888139BindingDB-show
CHEMBL109588446861806BindingDB-show
CHEMBL109682046887969BindingDB-show
CHEMBL109682146887970BindingDB-show
CHEMBL109682246887971BindingDB-show
CHEMBL109682346887972BindingDB-show
CHEMBL109820446887935BindingDB-show
CHEMBL109820546887936BindingDB-show
CHEMBL109820646887937BindingDB-show
CHEMBL109820746887938BindingDB-show
CHEMBL109820846887939BindingDB-show
CHEMBL109834946888058BindingDB-show
CHEMBL109849646887904BindingDB-show
CHEMBL109852646887973BindingDB-show
CHEMBL109865746888096BindingDB-show
CHEMBL109881646888010BindingDB-show
CHEMBL109881746888011BindingDB-show
CHEMBL109883946888057BindingDB-show
CHEMBL109900346861805BindingDB-show
CHEMBL109912546888012BindingDB-show
CHEMBL109913746888061BindingDB-show
CHEMBL109915146861804BindingDB-show
CHEMBL109915246888095BindingDB-show
CHEMBL1110169794487BindingDB-show
CHEMBL120903946911381BindingDB-show
CHEMBL121424946899573BindingDB-show
CHEMBL121432012066941BindingDB-show
CHEMBL121432115938557BindingDB-show
CHEMBL121432212066940BindingDB-show
CHEMBL1256744268050BindingDB-show
CHEMBL1364610243877BindingDB-show
CHEMBL19044744399654BindingDB-show
CHEMBL23261644430518BindingDB-show
CHEMBL23261744430520BindingDB-show
CHEMBL23281644430521BindingDB-show
CHEMBL23301917748220BindingDB-show
CHEMBL26238910996222BindingDB-show
CHEMBL28369510712038BindingDB-show
CHEMBL28439810887220BindingDB-show
CHEMBL28461711093710BindingDB-show
CHEMBL28551611828964BindingDB-show
CHEMBL28629710907843BindingDB-show
CHEMBL28654911060771BindingDB-show
CHEMBL28658610865717BindingDB-show
CHEMBL28686211115351BindingDB-show
CHEMBL28714510919571BindingDB-show
CHEMBL28731610974944BindingDB-show
CHEMBL28967211028005BindingDB-show
CHEMBL28988811060833BindingDB-show
CHEMBL3016811967472BindingDB-show
CHEMBL3209611060882BindingDB-show
CHEMBL3216011039158BindingDB-show
CHEMBL3220810920174BindingDB-show
CHEMBL3273211146161BindingDB-show
CHEMBL3283611763331BindingDB-show
CHEMBL3298211017835BindingDB-show
CHEMBL3431711039314BindingDB-show
CHEMBL34669111083515BindingDB-show
CHEMBL3476810930187BindingDB-show
CHEMBL3485210963315BindingDB-show
CHEMBL3497410864662BindingDB-show
CHEMBL3504310897133BindingDB-show
CHEMBL3533811028999BindingDB-show
CHEMBL3536711147037BindingDB-show
CHEMBL3538511735346BindingDB-show
CHEMBL3552811828627BindingDB-show
CHEMBL3652511017060BindingDB-show
CHEMBL36844423675285BindingDB-show
CHEMBL39003544430517BindingDB-show
CHEMBL39573444430523BindingDB-show
CHEMBL39598144430524BindingDB-show
CHEMBL40885610996432BindingDB-show
CHEMBL40885711967046BindingDB-show
CHEMBL41546611082579BindingDB-show
CHEMBL41641011966600BindingDB-show
CHEMBL44376925154732BindingDB-show
CHEMBL44808913927398BindingDB-show
CHEMBL44952725154729BindingDB-show
CHEMBL45025323704080BindingDB-show
CHEMBL45153825154731BindingDB-show
CHEMBL45527144144383BindingDB-show
CHEMBL45935644571848BindingDB-show
CHEMBL47124422506383BindingDB-show
CHEMBL47186913652393BindingDB-show
CHEMBL47577544571846BindingDB-show
CHEMBL47577644571849BindingDB-show
CHEMBL48214925154741BindingDB-show
CHEMBL48215044571892BindingDB-show
CHEMBL49956044571847BindingDB-show
CHEMBL50097725154730BindingDB-show
CHEMBL50986244592048BindingDB-show
CHEMBL56017545269009BindingDB-show
CHEMBL56586545485276BindingDB-show
CHEMBL56713945485270BindingDB-show
CHEMBL56754445485279BindingDB-show
CHEMBL56789645485283BindingDB-show
CHEMBL56817310586607BindingDB-show
CHEMBL56841710632698BindingDB-show
CHEMBL56885445375967BindingDB-show
CHEMBL57089445486144BindingDB-show
CHEMBL57133745375973BindingDB-show
CHEMBL57151912394434BindingDB-show
CHEMBL57173820195365BindingDB-show
CHEMBL57236645484187BindingDB-show
CHEMBL57816745485271BindingDB-show
CHEMBL58493945375968BindingDB-show
CHEMBL58575645486167BindingDB-show
CHEMBL678410375558BindingDB-show
CHEMBL691910081162BindingDB-show
Chinethazonum6307DrugBank-show
Chlorates104770BindingDB-show
chloride ion312BindingDB-show
Chloroaminophenamide67136BindingDB-show
Chlorothiazide2720DrugBank-show
Chlorothiazide2720SuperTarget-show
Chlorphthalidolone2732BindingDB-show
CID99098049909804BindingDB-show
cyanate105034BindingDB-show
CYCLOTHIAZIDE2910DrugBank-show
CYCLOTHIAZIDE5388988DrugBank-show
CYCLOTHIAZIDE2910SuperTarget-show
CYCLOTHIAZIDE5388988SuperTarget-show
Diaminopropyltetramethylenediamine1103BindingDB-show
Dichlorophenamide3038BindingDB-show
Dihydroflumethiazide3440BindingDB-show
Dihydroxybenzol5054BindingDB-show
Dihydroxychlorothiazidum3639BindingDB-show
Dihydroxychlorothiazidum3639DrugBank-show
Dihydroxychlorothiazidum3639SuperTarget-show
Dihydroxyphenylborane66827BindingDB-show
Disodium carbamoyl phosphate11970596BindingDB-show
Disodium hydrogen phosphate24203BindingDB-show
Disodium malate8736BindingDB-show
Disodium malonate8865BindingDB-show
Disodium selenate25960BindingDB-show
Ditiocarb sodium533728BindingDB-show
dl-O-Phosphoserine106BindingDB-show
Dobutamine hydrochloride36811BindingDB-show
Dorzolamide5284549BindingDB-show
DORZOLAMIDE92087BindingDB-show
Dorzolamide3154BindingDB-show
Ethoxazolamide3295BindingDB-show
Ethylumbelliferone35703BindingDB-show
ferulic acid445858BindingDB-show
fluoride28179BindingDB-show
Fluorosilicate28117BindingDB-show
formonitrile oxide521293BindingDB-show
FOSCARNET SODIUM44561BindingDB-show
Gallate370BindingDB-show
Harkoseride219078BindingDB-show
Heptafluoroniobium4712722BindingDB-show
hexafluoroarsenate23515BindingDB-show
Hexamethylenediamine16402BindingDB-show
Hexamethyltriethylenetetramine76509BindingDB-show
Hydrogen azide24530BindingDB-show
Hydrogen sulfate61778BindingDB-show
Hydrogencarbonate769BindingDB-show
hydrosulfide5047209BindingDB-show
Hydrotrichlorothiazide5560BindingDB-show
Hydrotrichlorothiazide5560DrugBank-show
Hydrotrichlorothiazide5560SuperTarget-show
Hydroxyacetanilide1983BindingDB-show
hydroxyaminomethanamide3657BindingDB-show
Hydroxybenzenecarboxylic acid135BindingDB-show
Hydroxycinnamic acid637542BindingDB-show
Hypertonalum3019DrugBank-show
Hypertonalum3019SuperTarget-show
Imatinib Methansulfonate5291BindingDB-show
indole sulfonamide, 8a25093413BindingDB-show
indole sulfonamide, 8b25093414BindingDB-show
indole sulfonamide, 8c25093415BindingDB-show
indole sulfonamide, 8d25093416BindingDB-show
indole sulfonamide, 8e25093417BindingDB-show
indole sulfonamide, 8f25093418BindingDB-show
indole sulfonamide, 8g25093419BindingDB-show
indole sulfonamide, 8h25093420BindingDB-show
indole sulfonamide, 8i25093421BindingDB-show
indole sulfonamide, 8j25093422BindingDB-show
indole sulfonamide, 8k25093423BindingDB-show
indole sulfonamide, 8l25093424BindingDB-show
indole sulfonamide, 8m25093425BindingDB-show
indole sulfonamide, 8n25093426BindingDB-show
indole sulfonamide, L14611919BindingDB-show
Inorganic bromides259BindingDB-show
iodate84927BindingDB-show
Iodide30165BindingDB-show
Isocyanide5975BindingDB-show
L-EPICATECHIN73160BindingDB-show
Methazolamide4100BindingDB-show
Methazolamide4100SuperTarget2 PMIDsshow
Methylchlorothiazide4121DrugBank-show
Methylchlorothiazide4121SuperTarget-show
Methylenediphosphonic acid16124BindingDB-show
Methylphosphonic acid13818BindingDB-show
Methylumbelliferone10748BindingDB-show
Metindamide3702BindingDB-show
METOLAZONE4170BindingDB-show
MLS000061036711717BindingDB-show
MLS000554938914298BindingDB-show
molybdate24621BindingDB-show
Monohydroxybenzene996BindingDB-show
Monophenylarsonic acid7365BindingDB-show
N,N'-Bis(2-aminoethyl)-1,3-propanediamine78479BindingDB-show
N-(Phosphonoacetyl)aspartic acid4312BindingDB-show
Natriumazetat517045BindingDB-show
Natriumhydrogenkarbonat516892BindingDB-show
Nilotinib644241BindingDB-show
NITRIC ACID944BindingDB-show
Nitrogen protoxide946BindingDB-show
NSC683852388776BindingDB-show
NSC685983389641BindingDB-show
NSC685984389642BindingDB-show
NSC698989394897BindingDB-show
NSC698996394904BindingDB-show
O-Phospho-DL-threonine1016BindingDB-show
Orthanilamide72894BindingDB-show
Ortho-hydroxycinnamic acid637540BindingDB-show
Orthohydroxybenzoic acid338BindingDB-show
p-Hydroxybenzonitrile13019BindingDB-show
p-Hydroxyphenylamine403BindingDB-show
Pentamethylenediamine273BindingDB-show
Perchlorate123351BindingDB-show
Periodate167232BindingDB-show
Phenylphosphonic acid15295BindingDB-show
Phosphonoformate3415BindingDB-show
Phosphotex24403BindingDB-show
Phthalhydroquinone289BindingDB-show
pyridinium deriv. 1011795548BindingDB-show
Resveratrol445154BindingDB-show
Salachlor2723810BindingDB-show
Silicate (SiO32-)115035BindingDB-show
silver mononitrate943BindingDB-show
Silybin3086637BindingDB-show
Sobenate517055BindingDB-show
Sodium alpha-hydroxypropionate23666456BindingDB-show
SODIUM CARBONATE10340BindingDB-show
Sodium citrate6224BindingDB-show
Sodium dihydrogenorthophosphate23672064BindingDB-show
Sodium oxalate6125BindingDB-show
Sodium perrhenate5107658BindingDB-show
Sodium persulfate62655BindingDB-show
Sodium phosphate24243BindingDB-show
SODIUM PYRUVATE23662274BindingDB-show
Sodium stannate25501BindingDB-show
Sodium thiocarbonate101753BindingDB-show
Spermidine trihydrochloride1102BindingDB-show
Sulfamic acid, decamethylene ester148885BindingDB-show
Sulfamide82267BindingDB-show
Sulphanilamide5333BindingDB-show
Syringic acid10742BindingDB-show
Tetrafluoroborate26255BindingDB-show
thiocyanate9322BindingDB-show
Topiramate5284627BindingDB-show
Topiramate5284627DrugBank-show
Topiramate5284627SuperTargetPMID 11804617show
triethylenetetraamine5565BindingDB-show
Trifluoromethylhydrothiazide3647BindingDB-show
Trifluoromethylhydrothiazide3647DrugBank-show
Trifluoromethylhydrothiazide3647SuperTarget-show
Valdecoxib119607BindingDB-show
Vanadium(V)trioxide26218BindingDB-show
Xanthaurine5280343BindingDB-show
ZINC02950199156219BindingDB-show
ZINC040730592781602BindingDB-show
ZINC047067172900806BindingDB-show
Zolamide84724BindingDB-show
Zonisamide5734BindingDB-show
Synonyms:
CA-IV
Carbonate dehydratase IV
Carbonic anhydrase 4
Carbonic anhydrase IV
Similar targets:
Uniprot name% Sequence similarity% Sequence identity
Q6FHI7_HUMAN100100
CAH4_RABIT78.568.3
CAH12_HUMAN4329.2
CAH12_RABIT42.730.1
CAH14_MOUSE41.930.3
CAH2_HUMAN41.129.6
CAH2_RABIT40.228.7
CAH5A_MOUSE39.626.9
CAH1_HUMAN38.325.6
CAH1_RABIT37.124.4
CAH_NEIGO36.825.8
CZCO_GEOKA33.818.7
Q96XN9_SULTO33.520.8
Q9XB59_ERWCA33.417
RIP0_DIACA33.118.8
PDAA_BACSU32.619
G3PA_SPIOL3217.4
DHB7_HUMAN31.919.6
GLK_ECOLI31.517.6
HMOX1_MOUSE31.218.6
DHOM_YEAST31.218.5
PNPH_BOVIN31.118.6
ASTA_PSEAE30.916.7
HMOX1_RAT30.919.4
KLK3_MACMU30.916.4
MCATL_HUMAN30.620.6
Q888A4_PSESM30.617.7
Q9Y9P9_AERPE30.516.8
Q9SLP6_MAIZE30.418.1
NB5R3_PIG30.416.9
Protein-Protein Interactions:
No data available