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Target Details

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Name:ALDOS
Uniprot name:C11B2_HUMAN
Accession Numbers:P19099 Q16726
EC-Number:1.14.15.4
1.14.15.5
Organism:Homo sapiens
Human
PDB IDs:-
KEGG Pathways:show KEGG Pathways
Drugs:
NamePubChem IDSourceReferencesInteraction
(2E)-2-(3H-imidazol-4-ylmethylidene)-3,4-dihydronaphthalen-1-one10376335BindingDB-show
(2E)-2-(3H-imidazol-4-ylmethylidene)-3,4-dihydronaphthalen-1-one10013868BindingDB-show
(3-Pyridylmethylene)indane 11b6539770BindingDB-show
(3-Pyridylmethylene)indane 19a6539773BindingDB-show
(3-Pyridylmethylene)indane 1a6539759BindingDB-show
(3-Pyridylmethylene)indane 1b6539760BindingDB-show
(3-Pyridylmethylene)indane 24a6539783BindingDB-show
(3-Pyridylmethylene)indane 25b6539785BindingDB-show
(3-Pyridylmethylene)indane 26a6539776BindingDB-show
(3-Pyridylmethylene)indane 5a6539763BindingDB-show
(3-Pyridylmethylene)indane 5b6539764BindingDB-show
(3-Pyridylmethylene)indane 7a6539765BindingDB-show
(3-Pyridylmethylene)indane 7b6539766BindingDB-show
(3-Pyridylmethylene)indane 9a6539767BindingDB-show
(3-Pyridylmethylene)indane 9b6539768BindingDB-show
(3-Pyridylmethylene)tetrahydronaphthalene 13b6539772BindingDB-show
(3-Pyridylmethylene)tetrahydronaphthalene 3b6539762BindingDB-show
(4-Pyridylmethylene)indane 10a6539794BindingDB-show
(4-Pyridylmethylene)indane 2b6539786BindingDB-show
(4-Pyridylmethylene)indane 6a6539788BindingDB-show
(4-Pyridylmethylene)indane 6b6539789BindingDB-show
(4-Pyridylmethylene)indane 8a6539792BindingDB-show
(4-Pyridylmethylene)indane 8b6539793BindingDB-show
(4-Pyridylmethylene)tetrahydronaphthalene 4a6539787BindingDB-show
(E)-3,4-Dihydro-2-(phenylmethylene)-1(2H)-naphthalenone5376779BindingDB-show
(isoquinolinemethylene)indane 30a6539812BindingDB-show
(S)Fadrozole13688212BindingDB-show
1-(4-bromobenzyl)-1H-imidazole2989557BindingDB-show
1-benzyl-5-phenyl-imidazole10444038BindingDB-show
3-(1H-imidazol-1-ylmethyl)aniline6481821BindingDB-show
3-(1H-imidazol-1-ylmethyl)benzonitrile24692916BindingDB-show
3-naphthalen-2-ylpyridine11845485BindingDB-show
Abiraterone132971BindingDB-show
Abiraterone mimetic, 1125033735BindingDB-show
Abiraterone mimetic, 1225033658BindingDB-show
Abiraterone mimetic, 1325033660BindingDB-show
Abiraterone mimetic, 1425033805BindingDB-show
Abiraterone mimetic, 1625033807BindingDB-show
Abiraterone mimetic, 1725033726BindingDB-show
Abiraterone mimetic, 1825033809BindingDB-show
Abiraterone mimetic, 1925033728BindingDB-show
Abiraterone mimetic, 225034657BindingDB-show
Abiraterone mimetic, 2025033811BindingDB-show
Abiraterone mimetic, 425033651BindingDB-show
Abiraterone mimetic, 525033730BindingDB-show
Abiraterone mimetic, 625033652BindingDB-show
Abiraterone mimetic, 725033731BindingDB-show
AC1O704P6539769BindingDB-show
AC1O704T6539771BindingDB-show
AC1O704Z6539774BindingDB-show
AC1O705J6539784BindingDB-show
AC1O706P6539805BindingDB-show
AC1O70G76540030BindingDB-show
acenaphthene derivative A11586681BindingDB-show
acenaphthene derivative B23644953BindingDB-show
Aminoglutethimide2145SuperCypPMID 11996015show
benazepril hydrochloride5362124SuperCypPMID 16505212show
BRN 47451793021558BindingDB-show
BRN 47484783021561BindingDB-show
CHEMBL117198746901444BindingDB-show
CHEMBL117199146854759BindingDB-show
CHEMBL117261149799005BindingDB-show
CHEMBL117277946901610BindingDB-show
CHEMBL117284246854760BindingDB-show
CHEMBL117284746854608BindingDB-show
CHEMBL117288246901446BindingDB-show
CHEMBL117325946854605BindingDB-show
CHEMBL117326046901611BindingDB-show
CHEMBL117332646854758BindingDB-show
CHEMBL117332746901445BindingDB-show
CHEMBL117333549799473BindingDB-show
CHEMBL120880149862652BindingDB-show
CHEMBL120947649862488BindingDB-show
CHEMBL120955349862547BindingDB-show
CHEMBL120955449862548BindingDB-show
CHEMBL120955549862549BindingDB-show
CHEMBL120955649862550BindingDB-show
CHEMBL120955749862551BindingDB-show
CHEMBL120955849862552BindingDB-show
CHEMBL120962349862599BindingDB-show
CHEMBL120962449862600BindingDB-show
CHEMBL120962549862601BindingDB-show
CHEMBL120962649862602BindingDB-show
CHEMBL120962749862603BindingDB-show
CHEMBL120962849862604BindingDB-show
CHEMBL120969349862650BindingDB-show
CHEMBL120969449862651BindingDB-show
CHEMBL120969549862653BindingDB-show
CHEMBL120969649862654BindingDB-show
CHEMBL12097759927427BindingDB-show
CHEMBL121466046901616BindingDB-show
CHEMBL121473546901784BindingDB-show
CHEMBL121473646901783BindingDB-show
CHEMBL121473746901927BindingDB-show
CHEMBL121473946901929BindingDB-show
CHEMBL121566449864181BindingDB-show
CHEMBL121566546901443BindingDB-show
CHEMBL121573046901613BindingDB-show
CHEMBL121573249864196BindingDB-show
CHEMBL15863510711620BindingDB-show
CHEMBL16249614231155BindingDB-show
CHEMBL16670910776192BindingDB-show
CHEMBL16678910656613BindingDB-show
CHEMBL16844410729612BindingDB-show
CHEMBL16870044381001BindingDB-show
CHEMBL16876210729611BindingDB-show
CHEMBL16908610800145BindingDB-show
CHEMBL16944910753431BindingDB-show
CHEMBL16966410610950BindingDB-show
CHEMBL1792226539795BindingDB-show
CHEMBL19334311557864BindingDB-show
CHEMBL19353411558270BindingDB-show
CHEMBL1936066539761BindingDB-show
CHEMBL19447211413434BindingDB-show
CHEMBL19557111514074BindingDB-show
CHEMBL19562911514098BindingDB-show
CHEMBL19599623644748BindingDB-show
CHEMBL19632811616637BindingDB-show
CHEMBL19679611601068BindingDB-show
CHEMBL19704411550235BindingDB-show
CHEMBL19757611529133BindingDB-show
CHEMBL21247311847320BindingDB-show
CHEMBL21358711847316BindingDB-show
CHEMBL21358811847317BindingDB-show
CHEMBL2876779815923BindingDB-show
CHEMBL35264510036028BindingDB-show
CHEMBL35306810727176BindingDB-show
CHEMBL35568110587179BindingDB-show
CHEMBL36296811506923BindingDB-show
CHEMBL3638496539813BindingDB-show
CHEMBL3683056539775BindingDB-show
CHEMBL37082221772021BindingDB-show
CHEMBL37143011680597BindingDB-show
CHEMBL37776611847318BindingDB-show
CHEMBL37777012229388BindingDB-show
CHEMBL38101411544009BindingDB-show
CHEMBL41334410489983BindingDB-show
CHEMBL41575310513321BindingDB-show
CHEMBL42455610752290BindingDB-show
CHEMBL43372810585362BindingDB-show
CHEMBL43880211594132BindingDB-show
CHEMBL44093010398594BindingDB-show
CHEMBL44525925034346BindingDB-show
CHEMBL44608325180109BindingDB-show
CHEMBL44677525130854BindingDB-show
CHEMBL44759124827305BindingDB-show
CHEMBL44806425034350BindingDB-show
CHEMBL44874318407230BindingDB-show
CHEMBL44989425034351BindingDB-show
CHEMBL45150525147691BindingDB-show
CHEMBL45316925034431BindingDB-show
CHEMBL45639025147692BindingDB-show
CHEMBL45742525180110BindingDB-show
CHEMBL45764025180299BindingDB-show
CHEMBL45764625180298BindingDB-show
CHEMBL45785625180503BindingDB-show
CHEMBL45785825180502BindingDB-show
CHEMBL45907112050204BindingDB-show
CHEMBL45996925180105BindingDB-show
CHEMBL45997025180305BindingDB-show
CHEMBL46017825180304BindingDB-show
CHEMBL46145725180303BindingDB-show
CHEMBL46145825180104BindingDB-show
CHEMBL46188425180107BindingDB-show
CHEMBL46188525180102BindingDB-show
CHEMBL46209225180306BindingDB-show
CHEMBL46209325180108BindingDB-show
CHEMBL49289125131495BindingDB-show
CHEMBL49289225129464BindingDB-show
CHEMBL49308225130848BindingDB-show
CHEMBL49308925129122BindingDB-show
CHEMBL49348525130517BindingDB-show
CHEMBL49431525131494BindingDB-show
CHEMBL49451525129462BindingDB-show
CHEMBL49471225129120BindingDB-show
CHEMBL49471324896569BindingDB-show
CHEMBL49533325131165BindingDB-show
CHEMBL49900725180500BindingDB-show
CHEMBL49904425034428BindingDB-show
CHEMBL49987144586852BindingDB-show
CHEMBL50014525034345BindingDB-show
CHEMBL50014625034347BindingDB-show
CHEMBL50039225034493BindingDB-show
CHEMBL50039325034426BindingDB-show
CHEMBL50039424754344BindingDB-show
CHEMBL50039525034425BindingDB-show
CHEMBL50042125034491BindingDB-show
CHEMBL50063625034344BindingDB-show
CHEMBL50066325034278BindingDB-show
CHEMBL50066425034430BindingDB-show
CHEMBL50066525034343BindingDB-show
CHEMBL50067625034492BindingDB-show
CHEMBL50174025034490BindingDB-show
CHEMBL50177925129463BindingDB-show
CHEMBL50226625034429BindingDB-show
CHEMBL50281825034432BindingDB-show
CHEMBL50282325034489BindingDB-show
CHEMBL50282425034348BindingDB-show
CHEMBL50815525180504BindingDB-show
CHEMBL50997125180103BindingDB-show
CHEMBL51132925180300BindingDB-show
CHEMBL51664344569291BindingDB-show
CHEMBL52286025129123BindingDB-show
CHEMBL52319625129117BindingDB-show
CHEMBL52401125129119BindingDB-show
CHEMBL52578525034427BindingDB-show
CHEMBL52633925034349BindingDB-show
CHEMBL59098715594569BindingDB-show
CHEMBL59122918785133BindingDB-show
CHEMBL59146544206480BindingDB-show
CHEMBL59169745103811BindingDB-show
CHEMBL59169811032034BindingDB-show
CHEMBL59261444206481BindingDB-show
CHEMBL59710145103809BindingDB-show
CHEMBL59717345103810BindingDB-show
CHEMBL59736810397593BindingDB-show
CHEMBL59757745103807BindingDB-show
CHEMBL59757844206482BindingDB-show
CHEMBL59839019902087BindingDB-show
CHEMBL59839110220337BindingDB-show
CHEMBL59839913688208BindingDB-show
CHEMBL59860645103806BindingDB-show
CHEMBL59878944206698BindingDB-show
CHEMBL59879045103914BindingDB-show
CHEMBL59881022466877BindingDB-show
CHEMBL59922246233602BindingDB-show
CHEMBL59922345103910BindingDB-show
CHEMBL59960110198247BindingDB-show
CHEMBL59960245103911BindingDB-show
CHEMBL59960345103912BindingDB-show
CHEMBL59962245103704BindingDB-show
CHEMBL59962345103705BindingDB-show
CHEMBL59962445103804BindingDB-show
CHEMBL60756745103915BindingDB-show
CHEMBL60786245103913BindingDB-show
CHEMBL60814014535954BindingDB-show
CHEMBL60843712229386BindingDB-show
CHEMBL61050145103808BindingDB-show
CHEMBL61051344187006BindingDB-show
CHEMBL61079445103805BindingDB-show
CHEMBL61168010632289BindingDB-show
CHEMBL6281113728862BindingDB-show
CID 1044350410331100BindingDB-show
Corticosterone222786SuperTarget-show
Corticosterone5753SuperTarget-show
Desoxycorticosteronum6166SuperCyp3 PMIDsshow
Dihydronaphthalene 106540054BindingDB-show
Dihydronaphthalene 116540055BindingDB-show
Dihydronaphthalene 26540047BindingDB-show
Dihydronaphthalene 46540049BindingDB-show
Dihydronaphthalene 56540057BindingDB-show
Dihydronaphthalene 66540050BindingDB-show
Dihydronaphthalene 76540051BindingDB-show
Dihydronaphthalene 86540052BindingDB-show
Dihydronaphthalene 96540053BindingDB-show
Electrocortin5839SuperCyp3 PMIDsshow
Epoxymexrenone150310SuperCypPMID 16505212show
Fadrozole Hydrochloride59693BindingDB-show
Hydrocorticosterone5754SuperCyp2 PMIDsshow
Hydroxyprogesterone6238SuperTarget-show
Hypnomidate667484BindingDB-show
Hypnomidate36339SuperCypPMID 8312688show
Hypnomidate667484SuperCypPMID 8312688show
Imidazolylmethyleneindane 2a6540032BindingDB-show
Imidazolylmethyleneindane 2b6540033BindingDB-show
Imidazolylmethyleneindane 5a6540035BindingDB-show
Imidazolylmethyleneindane 5b6540036BindingDB-show
Imidazolylmethyleneindane 7a6540038BindingDB-show
Imidazolylmethyleneindane 7b6540039BindingDB-show
Imidazolylmethyleneindane 8a6540040BindingDB-show
Imidazolylmethyleneindane 8b6540041BindingDB-show
Imidazolylmethyleneindane 9a6540042BindingDB-show
Imidazolylmethyleneindane 9b6540043BindingDB-show
Imidazolylmethylenetetrahydronaphthalene 1b6540031BindingDB-show
Imidazolylmethylenetetrahydronaphthalene 4b6540034BindingDB-show
Imidazolylmethylenetetrahydronaphthalene 6a6540037BindingDB-show
indene 16540046BindingDB-show
indene 126540058BindingDB-show
indene 36540048BindingDB-show
Ketoconazole456201BindingDB-show
Methochlopramide4168SuperCypPMID 7883831show
Mibefradil60663SuperCypPMID 16424797show
MLS00326948512354256BindingDB-show
N-Benzylimidazole77918BindingDB-show
NSC 2521291550302BindingDB-show
NSC 2707115702960BindingDB-show
ST0568151265319BindingDB-show
Styrylpyridine 166540056BindingDB-show
VALSARTAN60846SuperCypPMID 16043663show
ZINC001614012779191BindingDB-show
ZINC010197611236449BindingDB-show
ZINC046954965702471BindingDB-show
ZINC051286387515053BindingDB-show
Synonyms:
ALDOS
Aldosterone synthase
Aldosterone-synthesizing enzyme
CYPXIB2
Cytochrome P450 11B2, mitochondrial
P-450Aldo
P-450C18
Steroid 18-hydroxylase
Similar targets:
Uniprot name% Sequence similarity% Sequence identity
C11B1_HUMAN95.493.2
CP11A_HUMAN54.337.2
CP24A_HUMAN46.427.4
Q548T3_HUMAN44.630.1
CP27B_HUMAN44.630.1
CP27A_HUMAN43.726.9
CP3A2_RAT40.523.3
CP3A1_RAT40.322
CP2A7_HUMAN39.122.1
CP4F8_HUMAN38.723.7
CP3A5_HUMAN38.622.3
Q53GC3_HUMAN38.622.3
CP2A5_MOUSE38.421.4
CP2A6_HUMAN38.421.9
CP2AD_HUMAN37.821.5
CP2R1_HUMAN37.823.4
CP343_HUMAN37.721.2
Q6GRK0_HUMAN37.721.6
CP3A4_HUMAN37.721.6
Q5VX92_HUMAN37.621.3
CP2C9_HUMAN37.621.3
CP2B6_HUMAN37.420.9
Q5I2W7_HUMAN37.421.8
CP2J2_HUMAN37.121.6
Q6LEN2_HUMAN3721.2
CP46A_HUMAN3721.9
Q6NWU3_HUMAN36.820.1
Q86SK3_HUMAN36.821
CP2S1_HUMAN36.624.2
CP1A2_HUMAN36.619.9
Protein-Protein Interactions: