Home
Drugs
Targets
Pathways
Ontologies
Cyp450s
Adv.search
Help/FAQ

Target Details

add
Name:Agammaglobulinaemia tyrosine kinase
Uniprot name:BTK_HUMAN
Accession Numbers:Q06187 Q32ML5
EC-Number:2.7.10.2
Organism:Homo sapiens
Human
PDB IDs:1AWW 1AWX 1B55 1BTK 1BWN 1K2P 1QLY 2GE9 2Z0P
KEGG Pathways:show KEGG Pathways
Drugs:
NamePubChem IDSourceReferencesInteraction
3-((3R,4R)-4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperi9926791BindingDB-show
3-Amino-4,6-dimethylthieno[2,3-b]pyridine-2-carboxamide613528BindingDB-show
4-anilinoquinazoline deriv. 24708BindingDB-show
ABT-86911485656BindingDB-show
AMG 70611667893BindingDB-show
AST-48711409972BindingDB-show
Bio2_0004136610353BindingDB-show
Bosutinib5328940BindingDB-show
Canertinib156414BindingDB-show
CHEBI:1043465459219BindingDB-show
CHEBI:25992444329707BindingDB-show
CHEBI:54743644560358BindingDB-show
CHEBI:66834345481533BindingDB-show
CHEBI:66834445481534BindingDB-show
CHEMBL108119811755812BindingDB-show
CHEMBL109014346865419BindingDB-show
CHEMBL124070352945601BindingDB-show
CHEMBL124297746929544BindingDB-show
CHEMBL124320046929748BindingDB-show
CHEMBL124332646929857BindingDB-show
CHEMBL129074649838879BindingDB-show
CHEMBL20914811467730BindingDB-show
CHEMBL21594316086114BindingDB-show
CHEMBL23333844432441BindingDB-show
CHEMBL24635617748275BindingDB-show
CHEMBL2819579869943BindingDB-show
CHEMBL38666116086104BindingDB-show
CHEMBL38676011843159BindingDB-show
CHEMBL45833325154877BindingDB-show
CHEMBL45904444562721BindingDB-show
CHEMBL46546544570553BindingDB-show
CHEMBL48196844570599BindingDB-show
CHEMBL48196944570600BindingDB-show
CHEMBL50215625263033BindingDB-show
CHEMBL51764744570554BindingDB-show
CHEMBL56506124969301BindingDB-show
CHEMBL56892211723489BindingDB-show
CHEMBL57688723401001BindingDB-show
CHEMBL57698923400934BindingDB-show
CHEMBL57860110246246BindingDB-show
CHIR-26511656518BindingDB-show
CP-7247149874913BindingDB-show
Dasatinib3062316BindingDB-show
Doramapimod156422BindingDB-show
Erlotinib176870BindingDB-show
Gefitinib123631BindingDB-show
GW-258011617559BindingDB-show
Imatinib Methansulfonate5291BindingDB-show
Inositol 1,3,4,5-tetrakisphosphate107758DrugBank-show
Lapatinib ditosylate208908BindingDB-show
Lestaurtinib126565BindingDB-show
lfm-a139549280BindingDB-show
MLN805411712649BindingDB-show
Pazopanib10113978BindingDB-show
Pelitinib6445562BindingDB-show
PI-1039884685BindingDB-show
PKC-4129829523BindingDB-show
Roscovitine160355BindingDB-show
Ruboxistaurin153999BindingDB-show
RWJ-3872525330790BindingDB-show
S1018_Selleck9977819BindingDB-show
S1147_Selleck16007391BindingDB-show
S1526_Selleck24889392BindingDB-show
SB 2021905353940BindingDB-show
SB-4315424521392BindingDB-show
SNS-0323025986BindingDB-show
sorafenibum216239BindingDB-show
STAUROSPORINE44259BindingDB-show
staurosporine44299148BindingDB-show
SU-1481310138259BindingDB-show
Sunitinib5329102BindingDB-show
Tandutinib3038522BindingDB-show
Vandetanib3081361BindingDB-show
Vatalanib151194BindingDB-show
VX-6805494449BindingDB-show
VX-7453038525BindingDB-show
ZINC025397642756534BindingDB-show
Synonyms:
Agammaglobulinaemia tyrosine kinase
ATK
B-cell progenitor kinase
BPK
Bruton tyrosine kinase
Tyrosine-protein kinase BTK
Similar targets:
Uniprot name% Sequence similarity% Sequence identity
ITK_HUMAN66.349.7
HCK_HUMAN43.628
LCK_HUMAN41.126.3
SRC_RAT40.426.5
YES_HUMAN40.425.8
SRC_HUMAN40.426.5
FYN_HUMAN40.226.8
SRC_RSVSE39.426.2
CSK_HUMAN38.125.5
FGFR4_HUMAN35.121.3
KSYK_HUMAN3420.7
FGFR3_HUMAN33.720.6
KPCD_MOUSE33.617.8
ATGT_PYRHO32.218.1
BRAF_HUMAN32.117.5
KPC3_DROME3216.1
FGFR1_HUMAN31.920.6
FGFR1_MOUSE31.920.6
FGFR2_HUMAN31.619.3
RAF1_HUMAN31.518.2
Q4VA93_MOUSE31.416.7
RAF1_RAT31.217.5
RAF1_MOUSE31.217.7
Q99052_MOUSE31.120.8
CSF1R_HUMAN31.117.8
TPH2_RAT3116.9
KPCA_HUMAN3116.5
CCA_ARCFU30.917.4
ARAF_HUMAN30.918.2
CACP_MOUSE30.816.7
Protein-Protein Interactions: