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Target Details

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Name:Beta-lactamase
Uniprot name:AMPC_ECOLI
Accession Numbers:P00811 Q2M6F2
EC-Number:3.5.2.6
Organism:Escherichia coli
strain K12
PDB IDs:1C3B 1FCM 1FCN 1FCO 1FSW 1FSY 1GA9 1I5Q 1IEL 1IEM 1KDS 1KDW 1KE0 1KE3 1KE4 1KVL 1KVM 1L0D 1L0E 1L0F 1L0G 1L2S 1LL5 1LL9 1LLB 1MXO 1MY8 1O07 1PI4 1PI5 1XGI 1XGJ 2BLS 2FFY 2HDQ 2HDR 2HDS 2HDU 2I72 2P9V 2PU2 2PU4 2R9W 2R9X 2RCX 3BLS 3BM6 3FKV 3FKW 3GQZ 3GR2 3GRJ 3GSG 3GTC 3GV9 3GVB
KEGG Pathways:show KEGG Pathways
Drugs:
NamePubChem IDSourceReferencesInteraction
(2R)-2-benzoylsulfanyl-3-(4-phenylphenyl)propanoic Acid9928934BindingDB-show
(2R)-2-benzoylsulfanyl-3-dibenzofuran-2-yl-propanoic Acid10110056BindingDB-show
(2R)-3-(4-phenylphenyl)-2-sulfanyl-propanoic Acid9816592BindingDB-show
(2S)-2-acetylsulfanyl-3-(4-phenylphenyl)propanoic Acid9948275BindingDB-show
(2S)-2-acetylsulfanyl-3-dibenzofuran-2-yl-propanoic Acid9839836BindingDB-show
(2S)-2-benzoylsulfanyl-3-phenyl-propanoic Acid9943761BindingDB-show
(2S)-3-dibenzofuran-2-yl-2-sulfanyl-propanoic Acid9816938BindingDB-show
1,4-Phenylenediboronic Acid230478BindingDB-show
1-benzothiophen-3-ylboronic acid2776344BindingDB-show
1-Butaneboronic acid20479BindingDB-show
1-Naphthaleneboronic acid254532BindingDB-show
2′-Amino-3′-methoxyflavone4713BindingDB-show
2-Acetamidothiophene-3-carboxylic acid1477332BindingDB-show
2-acetylsulfanyl-3-phenyl-propanoic Acid9813292BindingDB-show
2-Formylphenylboronic acid292189BindingDB-show
2-Furanboronic acid2734357BindingDB-show
2-Naphthaleneboronic acid2734375BindingDB-show
2-Thiopheneboronic acid2733960BindingDB-show
2-{1-[2-(2-AMINO-THIAZOL-4-YL)-2-METHOXYIMINO-ACETYLAMINO]-2-OXO-ETHYL}-5,5-DIMETHYL-THIAZOLIDINE-4-CARBOXYLIC ACID9600418DrugBank-show
2-{1-[2-AMINO-2-(4-HYDROXY-PHENYL)-ACETYLAMINO]-2-OXO-ETHYL}-5,5-DIMETHYL-THIAZOLIDINE-4-CARBOXYLIC ACID5287717DrugBank-show
3,4-(Methylenedioxy)phenylboronic acid2734371BindingDB-show
3,4-dichloro-N-[5-[(5-chloro-1,3-benzothiazol-2-yl)sulfanyl]-1,3,4-thiadia2799782BindingDB-show
3-(4-BENZENESULFONYL-THIOPHENE-2-SULFONYLAMINO)-PHENYLBORONIC ACID1475BindingDB-show
3-(4-BENZENESULFONYL-THIOPHENE-2-SULFONYLAMINO)-PHENYLBORONIC ACID1475DrugBank-show
3-(Dansylamino)phenylboronic acid150643BindingDB-show
3-(Trifluoromethyl)phenylboronic acid2734388BindingDB-show
3-Carboxyphenylboronic acid2733957BindingDB-show
3-Formyl-2-thiopheneboronic acid2773429BindingDB-show
3-Thienylboronic acid581760BindingDB-show
3-[(4-sulfamoylphenyl)sulfamoyl]thiophene-2-carboxylic Acid2809622BindingDB-show
4,4'-Biphenylenediboronic acid2734608BindingDB-show
4,4'-Biphenylenediboronic acid2734608DrugBank-show
4-(CARBOXYVIN-2-YL)PHENYLBORONIC ACID5288001BindingDB-show
4-(CARBOXYVIN-2-YL)PHENYLBORONIC ACID5288001DrugBank-show
4-(p-Bromophenylazo)phenol5492867BindingDB-show
4-(Trifluoromethyl)phenylboronic acid2734389BindingDB-show
4-Amino-3-hydroxybenzoic acid137566BindingDB-show
4-Bromophenylboronic acid79599BindingDB-show
4-Fluorobenzeneboronic acid285645BindingDB-show
4-Formylphenylboronic acid591073BindingDB-show
4-Methoxyphenylboronic acid201262BindingDB-show
4-Methylthiophene-2-boronic acid2734373BindingDB-show
4-[(methylsulfonyl)amino]benzoic acid250653BindingDB-show
4428329844283298BindingDB-show
5-Acetyl-2-thiopheneboronic acid4143377BindingDB-show
5-bromo-n-(1-naphthyl)-2-furamide790290BindingDB-show
5-Chlorothiophene-2-boronic acid2734324BindingDB-show
6-methyl-2-phenylquinolin-4-ol730810BindingDB-show
9-phenanthrenylboronic acid11775704BindingDB-show
AC1MHDBT3000709BindingDB-show
AC1MXRD93770186BindingDB-show
AC1NQ6BI5190983BindingDB-show
AC1NWDD75703472BindingDB-show
AC1NYZMJ5844876BindingDB-show
AC1O0YTS6106109BindingDB-show
AC1O347U6270568BindingDB-show
ACYLATED CEFTAZIDIME9600404DrugBank-show
Aminobenzylpenicillin6249PROMISCUOUSPMID 3025996show
Anilinonaphthalenesulfonic acid1369BindingDB-show
Benzofuran-2-boronic acid2776266BindingDB-show
Benzothiophen-2-ylboronic acid2359BindingDB-show
Benzothiophen-2-ylboronic acid2359DrugBank-show
BiomolKI_0000335083BindingDB-show
Bisindolyl deriv. 115327726BindingDB-show
Cephalothinum6024DrugBank-show
Cephalothinum6024SuperTarget-show
CHEBI:15069544283256BindingDB-show
CHEBI:17121244292607BindingDB-show
CHEBI:17158620778641BindingDB-show
CHEBI:17231844293102BindingDB-show
CHEMBL11275844339259BindingDB-show
CHEMBL12778244351599BindingDB-show
CHEMBL12852344351612BindingDB-show
CHEMBL12909044351578BindingDB-show
CHEMBL12922644351610BindingDB-show
CHEMBL12965144351566BindingDB-show
CHEMBL13018723696922BindingDB-show
CHEMBL13085444351589BindingDB-show
CHEMBL14072323377398BindingDB-show
CHEMBL14392744360663BindingDB-show
CHEMBL17978218427400BindingDB-show
CHEMBL18048144392790BindingDB-show
CHEMBL18067944392789BindingDB-show
CHEMBL18159044392730BindingDB-show
CHEMBL18180444392783BindingDB-show
CHEMBL18252244392737BindingDB-show
CHEMBL18264444392729BindingDB-show
CHEMBL18469544392768BindingDB-show
CHEMBL18483044392746BindingDB-show
CHEMBL18489044392754BindingDB-show
CHEMBL18498444392774BindingDB-show
CHEMBL22666344422945BindingDB-show
CHEMBL26388244264224BindingDB-show
CHEMBL26762644264226BindingDB-show
CHEMBL26762744264287BindingDB-show
CHEMBL26786310386556BindingDB-show
CHEMBL28952644290416BindingDB-show
CHEMBL28997944290118BindingDB-show
CHEMBL29007244290371BindingDB-show
CHEMBL29532244290432BindingDB-show
CHEMBL29562544290473BindingDB-show
CHEMBL29673844290434BindingDB-show
CHEMBL29725344290388BindingDB-show
CHEMBL29767144290239BindingDB-show
CHEMBL29780544290423BindingDB-show
CHEMBL29851820778639BindingDB-show
CHEMBL29865344292877BindingDB-show
CHEMBL31358910135572BindingDB-show
CHEMBL3139779944009BindingDB-show
CHEMBL3141129952091BindingDB-show
CHEMBL3149219931547BindingDB-show
CHEMBL31514410221690BindingDB-show
CHEMBL3152319845518BindingDB-show
CHEMBL32255644339165BindingDB-show
CHEMBL32488744339180BindingDB-show
CHEMBL33663044351671BindingDB-show
CHEMBL33815744351651BindingDB-show
CHEMBL33835144351576BindingDB-show
CHEMBL33893344351657BindingDB-show
CHEMBL33960044351577BindingDB-show
CHEMBL33998144351564BindingDB-show
CHEMBL34035144351637BindingDB-show
CHEMBL34042344351613BindingDB-show
CHEMBL34070744351549BindingDB-show
CHEMBL34093744351565BindingDB-show
CHEMBL34148444351545BindingDB-show
CHEMBL34149644351611BindingDB-show
CHEMBL35990144392755BindingDB-show
CHEMBL36609944392745BindingDB-show
CHEMBL36803344392654BindingDB-show
CHEMBL37004144400590BindingDB-show
CHEMBL39078944422914BindingDB-show
CHEMBL41207344293166BindingDB-show
CHEMBL41249710138595BindingDB-show
CHEMBL41523444351672BindingDB-show
CHEMBL41591844290390BindingDB-show
CHEMBL41644744290386BindingDB-show
CHEMBL4211599912238BindingDB-show
CHEMBL4252844290248BindingDB-show
CHEMBL43249444293215BindingDB-show
CHEMBL4329539799576BindingDB-show
CHEMBL4395544290414BindingDB-show
CHEMBL4427444290475BindingDB-show
CHEMBL4427844290158BindingDB-show
CHEMBL4458844290131BindingDB-show
CHEMBL4475444290160BindingDB-show
CHEMBL4481344290477BindingDB-show
CHEMBL4493244290401BindingDB-show
CHEMBL4508444290241BindingDB-show
CHEMBL4513644290471BindingDB-show
CHEMBL4527344290237BindingDB-show
CHEMBL4549444293330BindingDB-show
CHEMBL4584120443948BindingDB-show
CHEMBL4598119697378BindingDB-show
CHEMBL4620220443961BindingDB-show
CHEMBL4647844290418BindingDB-show
CHEMBL4695844290404BindingDB-show
CHEMBL4719844290358BindingDB-show
CHEMBL4760620443937BindingDB-show
CHEMBL4762620778632BindingDB-show
CHEMBL4780820778642BindingDB-show
CHEMBL4833420778633BindingDB-show
CHEMBL4841244293235BindingDB-show
CHEMBL4856144293207BindingDB-show
CHEMBL4949844292991BindingDB-show
CHEMBL4988044293214BindingDB-show
CHEMBL622044264225BindingDB-show
CHEMBL622144264125BindingDB-show
CHEMBL626144264222BindingDB-show
CHEMBL628110001379BindingDB-show
CHEMBL628644264288BindingDB-show
CHEMBL629244264223BindingDB-show
CHEMBL630144264220BindingDB-show
CHEMBL630944264221BindingDB-show
CHEMBL631144264460BindingDB-show
CHEMBL829519845740BindingDB-show
CHEMBL8466210278502BindingDB-show
CHEMBL8466310160906BindingDB-show
CHEMBL8521910137345BindingDB-show
CHEMBL8541910291851BindingDB-show
CHEMBL8575410290877BindingDB-show
CHEMBL8768513662428BindingDB-show
Chlotrimazole2812BindingDB-show
Clavulansaeure5280980BindingDB-show
CLOXACILLIN DERIVATIVE2815BindingDB-show
Congo red11313BindingDB-show
Cystoceva5318432BindingDB-show
Dihydroxyphenylborane66827BindingDB-show
Diphenylborinic acid17498BindingDB-show
dmbi5353593BindingDB-show
Fasudil hydrochloride3547BindingDB-show
Gossypol3503BindingDB-show
HTC657106BindingDB-show
HYDROLYZED CEPHALOTHIN5289466DrugBank-show
Indirubin5318433BindingDB-show
Indole-5-boronic acid2734361BindingDB-show
Lopac-U-1205354033BindingDB-show
LORACABEF5288704DrugBank-show
LS-19069624848417BindingDB-show
M-AMINOPHENYLBORONIC ACID92269BindingDB-show
M-AMINOPHENYLBORONIC ACID92269DrugBank-show
m-Nitrobenzeneboronic acid1677BindingDB-show
m-Nitrobenzeneboronic acid1677DrugBank-show
Maybridge1_0038282809655BindingDB-show
Maybridge3_0017062809668BindingDB-show
Methylchlorphenylisoxazoryl-penicillin6098DrugBank-show
Methylchlorphenylisoxazoryl-penicillin6098SuperTarget-show
MLS0000889682193049BindingDB-show
MOXALACTAM DERIVATIVE5288830DrugBank-show
N-Benzoyl-D-alanylmercaptoacetic acid5702523BindingDB-show
Naphuride5361BindingDB-show
nchembio.65-comp136508446BindingDB-show
p-Carboxyphenylboronic acid312183BindingDB-show
p-Carboxyphenylboronic acid312183DrugBank-show
p-Tolylboronic acid79799BindingDB-show
Permanent Pink2844776BindingDB-show
propanoic acid, 3-(2-benzothiazolylthio)-224561BindingDB-show
rottlerin5281847BindingDB-show
saccharose5988DrugBank-show
SB 203580176155BindingDB-show
SC-683765174BindingDB-show
sodium thiophenecarboxylate10700BindingDB-show
Staurosporine aglycone3815BindingDB-show
STC446853BindingDB-show
STK3966453834960BindingDB-show
STK3987741258939BindingDB-show
Succinonitrile, bis(amino(o-aminophenylthio)methylene)-3006531BindingDB-show
Sulbactam130313BindingDB-show
Sulbactam130313PROMISCUOUSPMID 3025996show
Sulconazole5318BindingDB-show
Tazobactam123630BindingDB-show
Tetraiodophenolphthalein207344BindingDB-show
Tocris-14723943541BindingDB-show
wortmannin312145BindingDB-show
Xanthaurine5280343BindingDB-show
y-27632448042BindingDB-show
ZINC001369421538822BindingDB-show
ZINC006931211026627BindingDB-show
ZINC015322161549065BindingDB-show
ZINC018097381592861BindingDB-show
ZINC030297195814800BindingDB-show
[(2-thiophen-2-ylacetyl)amino]methylboronic Acid2671BindingDB-show
Synonyms:
Beta-lactamase
Cephalosporinase
Similar targets:
Uniprot name% Sequence similarity% Sequence identity
Q59276_CITFR86.176.4
AMPC_CITFR85.675.9
AMPC_ENTCL82.969
ESTB_BURGA37.421.2
DHB2_HUMAN34.517.8
AADAT_HUMAN33.319.2
ASPQ_PSEPK32.919
LDHD_LACHE32.621.3
DCDA_ECOLI32.620.5
PSTS_ECOLI32.519.4
ALSB_ECOLI32.419.3
DAC_STRSR32.222
BLA1_BACCE3218.5
NDUAA_HUMAN31.718.1
Q9ZIV5_BRAJA31.418.1
BMP2_RAT31.217.7
O66145_CITAM31.119.7
Q9RYA6_DEIRA31.116.5
ARAF_ECOLI3117.7
Q2TU84_HUMAN3116.8
AATC_HUMAN3116.8
BFRA_THEMA30.718.1
HA11_MOUSE30.619.8
SERC_HUMAN30.417.8
DHSO_HUMAN30.318.4
NAPE_ENTFA30.317.2
FBPA_HAEIN30.217.2
LDHA_HUMAN30.216.2
PON1_HUMAN30.119.7
Q44244_9PSEU30.117.9
Protein-Protein Interactions:
No data available