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Target Details

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Name:Alpha-2C adrenergic receptor
Uniprot name:ADA2C_HUMAN
Accession Numbers:P18825 P35369 Q9HB49
EC-Number:-
Organism:Homo sapiens
Human
PDB IDs:-
KEGG Pathways:show KEGG Pathways
Drugs:
NamePubChem IDSourceReferencesInteraction
1,2,3,4-Tetrahydroisoquinoline-7-sulfonamide5226BindingDB-show
1-(2-aminopropyl)-2H-indazol-6-one9834183BindingDB-show
1-(2-aminopropyl)-2H-indazol-6-one11500503BindingDB-show
2-Chloro-6-(1-piperazinyl)pyrazine107992BindingDB-show
2-Fluoro-3-[1-hydroxy-2-(methylamino)ethyl]phenol127901BindingDB-show
2-Fluoro-5-[1-hydroxy-2-(methylamino)ethyl]phenol127904BindingDB-show
2-[4-[4-(3-methoxyphenyl)piperazin-1-yl]butyl]-4-methyl-1,2,4-triazine-3,511948707BindingDB-show
2-[4-[4-(7-methoxynaphthalen-1-yl)piperazin-1-yl]butyl]-4-methyl-1,2,4-tri11676174BindingDB-show
3-fluoro-4-(1-hydroxy-2-methylamino-ethyl)benzene-1,2-diol10420352BindingDB-show
3-Fluoronorepinephrine172745BindingDB-show
4-(2-Amino-1-hydroxyethyl)-5-fluoro-1,2-benzenediol1862BindingDB-show
4-DESMETHYLOLANZAPINE9948206BindingDB-show
4-Fluoro-3-[1-hydroxy-2-(methylamino)ethyl]phenol183823BindingDB-show
4-[(Z)-1-naphthalen-1-ylprop-1-enyl]-3H-imidazole9991628BindingDB-show
4445768844457688BindingDB-show
5-Methylurapidil5640BindingDB-show
7,8-Dichloro-1,2,3,4-tetrahydroisoquinoline123920BindingDB-show
7-Methoxy-1,2,3,4-tetrahydro-9H-pyrido[3,4-b]indole599482BindingDB-show
7-sulfonamide-THIQ 1310263774BindingDB-show
740873-06-711430856BindingDB-show
8-(1-Piperazinyl)imidazo(1,2-a)pyrazine131268BindingDB-show
9-Allyloxy-6-chloro-3-methyl-2,3,4,5-tetrahydro-1H-benzazepine135152BindingDB-show
AC1L1CUF2068BindingDB-show
AC1L30EQ132111BindingDB-show
AC1L4G4B185076BindingDB-show
AC1MJ5UG3086247BindingDB-show
AC1MJ6A73086489BindingDB-show
Agn 190851131829BindingDB-show
Albacon23615857BindingDB-show
Ambcb2969942944579184BindingDB-show
Apraclonidine2216BindingDB-show
benalfocin123981BindingDB-show
Benzenethanamine, 2-fluoro-2',4,5-trihydroxy-N-methyl-541604BindingDB-show
Bethanidine6324770DrugBank-show
Bethanidine2368DrugBank-show
Bethanidine2368SuperTarget-show
Bethanidine6324770SuperTarget-show
Biomol-NT_0001263416533BindingDB-show
Brimonidine2435BindingDB-show
Brimonidine2435DrugBank-show
Brimonidine2435SuperTargetPMID 9534022show
BRN 5117597540335BindingDB-show
C16H22ClNO122295BindingDB-show
CBDivE_0050283072540BindingDB-show
CHEBI:29913812841602BindingDB-show
CHEBI:37206917698BindingDB-show
CHEBI:64403444279114BindingDB-show
CHEBI:64403544278909BindingDB-show
CHEBI:64559744314891BindingDB-show
CHEBI:64562744314569BindingDB-show
CHEBI:64569944315005BindingDB-show
CHEBI:64581444461506BindingDB-show
CHEBI:64630644331469BindingDB-show
CHEBI:64648944331500BindingDB-show
CHEBI:64851444377741BindingDB-show
CHEBI:64857044377974BindingDB-show
CHEBI:64860744377972BindingDB-show
CHEBI:64993444438146BindingDB-show
CHEBI:65066244278910BindingDB-show
CHEBI:65246644377917BindingDB-show
CHEBI:65247144377721BindingDB-show
CHEBI:65250044377537BindingDB-show
CHEBI:65252844377959BindingDB-show
CHEMBL10004544329027BindingDB-show
CHEMBL1004549840400BindingDB-show
CHEMBL10087944330168BindingDB-show
CHEMBL10136144330857BindingDB-show
CHEMBL10141144330621BindingDB-show
CHEMBL10159644330668BindingDB-show
CHEMBL101910214826BindingDB-show
CHEMBL102210489502BindingDB-show
CHEMBL10532810513867BindingDB-show
CHEMBL107907944471685BindingDB-show
CHEMBL108551046891598BindingDB-show
CHEMBL11203844340624BindingDB-show
CHEMBL11235110332138BindingDB-show
CHEMBL11235744340588BindingDB-show
CHEMBL11296410401405BindingDB-show
CHEMBL12049112841606BindingDB-show
CHEMBL12062612841579BindingDB-show
CHEMBL12096412841598BindingDB-show
CHEMBL12132012841600BindingDB-show
CHEMBL12140812841608BindingDB-show
CHEMBL12167712841594BindingDB-show
CHEMBL12205044348140BindingDB-show
CHEMBL122452746869265BindingDB-show
CHEMBL12267144348045BindingDB-show
CHEMBL12310244348164BindingDB-show
CHEMBL1231389839317BindingDB-show
CHEMBL12318812841585BindingDB-show
CHEMBL12344810946567BindingDB-show
CHEMBL12376944348163BindingDB-show
CHEMBL1244029851803BindingDB-show
CHEMBL12529444348028BindingDB-show
CHEMBL125822349783209BindingDB-show
CHEMBL125845249783415BindingDB-show
CHEMBL125867149783419BindingDB-show
CHEMBL1359111021868BindingDB-show
CHEMBL1372110967219BindingDB-show
CHEMBL1379311043404BindingDB-show
CHEMBL1381011075930BindingDB-show
CHEMBL138569891167BindingDB-show
CHEMBL1385811055234BindingDB-show
CHEMBL1389313425090BindingDB-show
CHEMBL1391813425094BindingDB-show
CHEMBL1393811770304BindingDB-show
CHEMBL1394010868559BindingDB-show
CHEMBL1395511042529BindingDB-show
CHEMBL1395811031718BindingDB-show
CHEMBL139879837537BindingDB-show
CHEMBL1402810242469BindingDB-show
CHEMBL1411010933317BindingDB-show
CHEMBL1415411781522BindingDB-show
CHEMBL1424210354045BindingDB-show
CHEMBL1501619906978BindingDB-show
CHEMBL16279805944BindingDB-show
CHEMBL16454044377985BindingDB-show
CHEMBL17358120447226BindingDB-show
CHEMBL17571044387787BindingDB-show
CHEMBL17624044387801BindingDB-show
CHEMBL17757644387757BindingDB-show
CHEMBL17964810758200BindingDB-show
CHEMBL18135011329138BindingDB-show
CHEMBL18690944288600BindingDB-show
CHEMBL1871969800737BindingDB-show
CHEMBL1891189804849BindingDB-show
CHEMBL19343544401105BindingDB-show
CHEMBL19345844402531BindingDB-show
CHEMBL19363944401164BindingDB-show
CHEMBL19465944401041BindingDB-show
CHEMBL19483711539632BindingDB-show
CHEMBL1948499883506BindingDB-show
CHEMBL19570644401194BindingDB-show
CHEMBL19592544402583BindingDB-show
CHEMBL19606444402345BindingDB-show
CHEMBL19634444402352BindingDB-show
CHEMBL19640044402476BindingDB-show
CHEMBL19645111203101BindingDB-show
CHEMBL19697044405404BindingDB-show
CHEMBL19873344405513BindingDB-show
CHEMBL19889611680583BindingDB-show
CHEMBL19900844405471BindingDB-show
CHEMBL20037544405495BindingDB-show
CHEMBL20056044405494BindingDB-show
CHEMBL20056344405499BindingDB-show
CHEMBL20091044405493BindingDB-show
CHEMBL20123211237664BindingDB-show
CHEMBL20187811508052BindingDB-show
CHEMBL20194644407083BindingDB-show
CHEMBL21057813091268BindingDB-show
CHEMBL21195244413779BindingDB-show
CHEMBL21391944417404BindingDB-show
CHEMBL21466116090633BindingDB-show
CHEMBL21499610045088BindingDB-show
CHEMBL21607216090599BindingDB-show
CHEMBL21619716090627BindingDB-show
CHEMBL21629010319299BindingDB-show
CHEMBL2163999923679BindingDB-show
CHEMBL21646410251036BindingDB-show
CHEMBL21667416090594BindingDB-show
CHEMBL21672716090626BindingDB-show
CHEMBL21717716090596BindingDB-show
CHEMBL21718016090634BindingDB-show
CHEMBL21720216090622BindingDB-show
CHEMBL21720310362866BindingDB-show
CHEMBL21725316090631BindingDB-show
CHEMBL21725416090601BindingDB-show
CHEMBL21727816090624BindingDB-show
CHEMBL21729925142456BindingDB-show
CHEMBL2173412406841BindingDB-show
CHEMBL21745216090625BindingDB-show
CHEMBL21754216090602BindingDB-show
CHEMBL21756716090623BindingDB-show
CHEMBL21756816090598BindingDB-show
CHEMBL21776816090635BindingDB-show
CHEMBL21845710070896BindingDB-show
CHEMBL21867516090630BindingDB-show
CHEMBL21867910473701BindingDB-show
CHEMBL21873011741010BindingDB-show
CHEMBL2207313805911BindingDB-show
CHEMBL22663644424855BindingDB-show
CHEMBL22942916737207BindingDB-show
CHEMBL23086117755543BindingDB-show
CHEMBL24210210019859BindingDB-show
CHEMBL24269316757089BindingDB-show
CHEMBL24283929181446BindingDB-show
CHEMBL24498617755537BindingDB-show
CHEMBL24498717755548BindingDB-show
CHEMBL24622844438147BindingDB-show
CHEMBL24622944438148BindingDB-show
CHEMBL24663944438152BindingDB-show
CHEMBL24685211225732BindingDB-show
CHEMBL24766444438166BindingDB-show
CHEMBL24766544438168BindingDB-show
CHEMBL26290110044968BindingDB-show
CHEMBL26342444330617BindingDB-show
CHEMBL26707411747682BindingDB-show
CHEMBL26746410132386BindingDB-show
CHEMBL26821710474679BindingDB-show
CHEMBL2682589928332BindingDB-show
CHEMBL2687589890547BindingDB-show
CHEMBL27431511053968BindingDB-show
CHEMBL27478410922759BindingDB-show
CHEMBL27603511138988BindingDB-show
CHEMBL27641710317643BindingDB-show
CHEMBL28106413473217BindingDB-show
CHEMBL2837349809007BindingDB-show
CHEMBL2842139815633BindingDB-show
CHEMBL28479510220232BindingDB-show
CHEMBL28877210436842BindingDB-show
CHEMBL289029870702BindingDB-show
CHEMBL2908609960497BindingDB-show
CHEMBL29116644289035BindingDB-show
CHEMBL29500144288874BindingDB-show
CHEMBL29539544288769BindingDB-show
CHEMBL29772613387304BindingDB-show
CHEMBL29812444293794BindingDB-show
CHEMBL2989369837551BindingDB-show
CHEMBL29978613387299BindingDB-show
CHEMBL2998799982218BindingDB-show
CHEMBL30007344293793BindingDB-show
CHEMBL30038811119320BindingDB-show
CHEMBL307399816063BindingDB-show
CHEMBL3080429837525BindingDB-show
CHEMBL30857010176999BindingDB-show
CHEMBL30872710130620BindingDB-show
CHEMBL30886310609673BindingDB-show
CHEMBL3091114548284BindingDB-show
CHEMBL3106213473220BindingDB-show
CHEMBL3119513538579BindingDB-show
CHEMBL3133213538583BindingDB-show
CHEMBL31363110035109BindingDB-show
CHEMBL31649544328654BindingDB-show
CHEMBL317149848518BindingDB-show
CHEMBL31823516655023BindingDB-show
CHEMBL31911911225779BindingDB-show
CHEMBL31953044330114BindingDB-show
CHEMBL31957344330584BindingDB-show
CHEMBL32073644328920BindingDB-show
CHEMBL32357910032383BindingDB-show
CHEMBL32787544325049BindingDB-show
CHEMBL32811444324765BindingDB-show
CHEMBL32819544330369BindingDB-show
CHEMBL32837744324859BindingDB-show
CHEMBL32863110028898BindingDB-show
CHEMBL32873544325075BindingDB-show
CHEMBL32906544330368BindingDB-show
CHEMBL33198112841592BindingDB-show
CHEMBL33327112841604BindingDB-show
CHEMBL33988312841596BindingDB-show
CHEMBL3420299859238BindingDB-show
CHEMBL35552713338337BindingDB-show
CHEMBL3604199978693BindingDB-show
CHEMBL36269911338418BindingDB-show
CHEMBL36295411653915BindingDB-show
CHEMBL3635379823464BindingDB-show
CHEMBL36358144401106BindingDB-show
CHEMBL36427044401042BindingDB-show
CHEMBL36662344387794BindingDB-show
CHEMBL36993844402346BindingDB-show
CHEMBL37000544402579BindingDB-show
CHEMBL37135244401612BindingDB-show
CHEMBL37151644402477BindingDB-show
CHEMBL38231044402344BindingDB-show
CHEMBL38357711522273BindingDB-show
CHEMBL38397816090595BindingDB-show
CHEMBL38431816090597BindingDB-show
CHEMBL38492516090621BindingDB-show
CHEMBL38572216090632BindingDB-show
CHEMBL38616916090628BindingDB-show
CHEMBL39024617755236BindingDB-show
CHEMBL39071844424854BindingDB-show
CHEMBL39277144438161BindingDB-show
CHEMBL39299111750482BindingDB-show
CHEMBL39299216725934BindingDB-show
CHEMBL39359711293787BindingDB-show
CHEMBL39421844438167BindingDB-show
CHEMBL40214344455426BindingDB-show
CHEMBL4065010527469BindingDB-show
CHEMBL41871615407019BindingDB-show
CHEMBL41931644324972BindingDB-show
CHEMBL41933644330427BindingDB-show
CHEMBL41989444330609BindingDB-show
CHEMBL42065210658207BindingDB-show
CHEMBL42083044330571BindingDB-show
CHEMBL42259744324887BindingDB-show
CHEMBL4233544288847BindingDB-show
CHEMBL42491710475736BindingDB-show
CHEMBL42562210177445BindingDB-show
CHEMBL42580310109188BindingDB-show
CHEMBL42598310045713BindingDB-show
CHEMBL42840744438165BindingDB-show
CHEMBL4321559859437BindingDB-show
CHEMBL4325799859861BindingDB-show
CHEMBL43308313387301BindingDB-show
CHEMBL43373013392482BindingDB-show
CHEMBL434919827677BindingDB-show
CHEMBL43530144401243BindingDB-show
CHEMBL4359444288877BindingDB-show
CHEMBL43769944405498BindingDB-show
CHEMBL4386044288945BindingDB-show
CHEMBL43986421584293BindingDB-show
CHEMBL4405129818826BindingDB-show
CHEMBL44059416090600BindingDB-show
CHEMBL44226813538585BindingDB-show
CHEMBL44240010465137BindingDB-show
CHEMBL44479321539587BindingDB-show
CHEMBL47656944579230BindingDB-show
CHEMBL47677444579231BindingDB-show
CHEMBL47683944582678BindingDB-show
CHEMBL47760844579228BindingDB-show
CHEMBL47781644579185BindingDB-show
CHEMBL47802644579186BindingDB-show
CHEMBL48897444579303BindingDB-show
CHEMBL49063244582705BindingDB-show
CHEMBL49141944579271BindingDB-show
CHEMBL49142044579272BindingDB-show
CHEMBL492849816048BindingDB-show
CHEMBL4939510198248BindingDB-show
CHEMBL5039010198552BindingDB-show
CHEMBL507699881158BindingDB-show
CHEMBL51483744579229BindingDB-show
CHEMBL51517016220269BindingDB-show
CHEMBL51533144579187BindingDB-show
CHEMBL51608844582676BindingDB-show
CHEMBL5196315054187BindingDB-show
CHEMBL5206913720763BindingDB-show
CHEMBL52415325110718BindingDB-show
CHEMBL5247315054190BindingDB-show
CHEMBL5333513387308BindingDB-show
CHEMBL5533815054192BindingDB-show
CHEMBL5552815054189BindingDB-show
CHEMBL5716315054191BindingDB-show
CHEMBL5818611044324BindingDB-show
CHEMBL5818710977777BindingDB-show
CHEMBL58455445482789BindingDB-show
CHEMBL59061546225029BindingDB-show
CHEMBL59544911957735BindingDB-show
CHEMBL59606746225253BindingDB-show
CHEMBL5971915407445BindingDB-show
CHEMBL6003111064673BindingDB-show
CHEMBL6018611031586BindingDB-show
CHEMBL60285010040286BindingDB-show
CHEMBL60856010356463BindingDB-show
CHEMBL6168910978438BindingDB-show
CHEMBL6209544302352BindingDB-show
CHEMBL6210711022127BindingDB-show
CHEMBL704099816035BindingDB-show
CHEMBL721079816604BindingDB-show
CHEMBL7444910632290BindingDB-show
CHEMBL7454410655607BindingDB-show
CHEMBL752579795515BindingDB-show
CHEMBL7538944313966BindingDB-show
CHEMBL754919794524BindingDB-show
CHEMBL7645710490084BindingDB-show
CHEMBL773959796720BindingDB-show
CHEMBL7791310198135BindingDB-show
CHEMBL7819010682720BindingDB-show
CHEMBL88314928441BindingDB-show
CHEMBL9024744324906BindingDB-show
CHEMBL9041944324725BindingDB-show
CHEMBL9084344324900BindingDB-show
CHEMBL9094344324937BindingDB-show
CHEMBL9096644325038BindingDB-show
CHEMBL9099710220053BindingDB-show
CHEMBL9115744324800BindingDB-show
CHEMBL9129744325028BindingDB-show
CHEMBL9182444325027BindingDB-show
CHEMBL9249644325079BindingDB-show
CHEMBL9286044324737BindingDB-show
CHEMBL9317144325050BindingDB-show
CHEMBL934899846548BindingDB-show
CHEMBL9380144325044BindingDB-show
CHEMBL9412944215744BindingDB-show
CHEMBL9419044325097BindingDB-show
CHEMBL944111390143BindingDB-show
CHEMBL9443544324860BindingDB-show
CHEMBL9521844330598BindingDB-show
CHEMBL9529044328799BindingDB-show
CHEMBL9557844328801BindingDB-show
CHEMBL9806315853467BindingDB-show
CHEMBL9854110480357BindingDB-show
CHEMBL9864644330653BindingDB-show
CHEMBL9888944330679BindingDB-show
CHEMBL9986444329026BindingDB-show
CHEMBL9986844330635BindingDB-show
CHEMBL9991644330645BindingDB-show
ChemDiv1_0192594567175BindingDB-show
CID 1036536411743399BindingDB-show
CID 1055538310326069BindingDB-show
CID 1126748811186523BindingDB-show
CID 98307419830741BindingDB-show
CID 98560419856041BindingDB-show
CID 98948189894818BindingDB-show
CID 99283439928343BindingDB-show
Clonidinhydrochlorid2803BindingDB-show
Clonidinhydrochlorid2803SuperTargetPMID 10051122show
Clozapine2818BindingDB-show
Corynanthine8969BindingDB-show
corynanthine92766BindingDB-show
Corynanthine8969DrugBank-show
Corynanthine8969SuperTarget-show
Debrisochinum2966DrugBank-show
dl-Phenylephrine4782BindingDB-show
Doxazosin3157BindingDB-show
Droxidopa443940DrugBank-show
Droxidopa92974DrugBank-show
Enteropride2769BindingDB-show
Fenoldopam3341DrugBank-show
Guanadrel38521DrugBank-show
Guanethidine3518DrugBank-show
Guanfacine Monohydrochloride3519SuperTargetPMID 10374721show
Haloperidol3559BindingDB-show
hydroxyethylrutoside5280805BindingDB-show
Idazoxan hydrochloride54459BindingDB-show
Imidazolidine,2-(2-methylphenylimino)-142067BindingDB-show
Indoramine33625BindingDB-show
Ipsapironum56971BindingDB-show
Leucoharmine5280953BindingDB-show
Levomedetomidine68602BindingDB-show
Levonorepinephrine5814BindingDB-show
Levonorepinephrine439260DrugBank-show
Levonorepinephrine5814DrugBank-show
Lofexidine hydrochloride30668DrugBank-show
Lofexidine hydrochloride30668SuperTarget-show
Metasynephrine6041SuperTargetPMID 10749700show
Methylaminoethanolcatechol5816BindingDB-show
MF06500003028481BindingDB-show
Mianserin Monohydrochloride4184BindingDB-show
Miquelianin12304323BindingDB-show
Mirtazapin4205BindingDB-show
Moxonidine hydrochloride4810BindingDB-show
N-(4-methoxyphenyl)-4,5-dihydro-1H-imidazol-2-amine411679BindingDB-show
N-Demethyllysergic acid diethylamide169713BindingDB-show
Natriumchlorid5234SuperTarget-show
Nicardipine hydrochloride4474BindingDB-show
NIGULDIPINE60602BindingDB-show
NITD60944469321BindingDB-show
norepinephrine951BindingDB-show
Olanzapine4585BindingDB-show
Oximetazolinum4636BindingDB-show
p-Iodoclonidine hydrochloride4656BindingDB-show
PDSP1_000858126225BindingDB-show
PDSP1_00138910331436BindingDB-show
PDSP1_0016651268096BindingDB-show
PDSP2_0004526918097BindingDB-show
PDSP2_001604132337BindingDB-show
Phentolamine Methanesulfonate5775BindingDB-show
Phentolamine Methanesulfonate5775SuperTarget-show
Quetiapine5002BindingDB-show
Racepinephrine838BindingDB-show
Rauwolscine643606BindingDB-show
Risperidonum5073BindingDB-show
SC 53606133999BindingDB-show
SC-524919885123BindingDB-show
sertindole hydrochloride60149BindingDB-show
TAMSULOSIN HYDROCHLORIDE129211BindingDB-show
Terazosin hydrochloride4893BindingDB-show
Terazosin hydrochloride5401BindingDB-show
tetrahydroisoquinoline (THIQ) deriv. 25288606BindingDB-show
Tetrahydroserpentine441975BindingDB-show
tizanidine hydrochloride5487SuperTargetPMID 12145058show
Vilazodone6918314BindingDB-show
WB41015685BindingDB-show
Xylomethazoline5709BindingDB-show
YOHIMBINE HYDROCHLORIDE6169BindingDB-show
Zafirlukast5717BindingDB-show
Ziprasidone hydrochloride60854BindingDB-show
Zotepine5736BindingDB-show
Synonyms:
Alpha-2 adrenergic receptor subtype C4
Alpha-2C adrenergic receptor
Alpha-2C adrenoceptor
Alpha-2C adrenoreceptor
Similar targets:
Uniprot name% Sequence similarity% Sequence identity
ADA2A_HUMAN58.750.6
ADA2B_HUMAN56.547.2
5HT1D_HUMAN47.931
Q5ZGX3_HUMAN46.932.7
5HT1A_HUMAN46.932.7
DRD2_HUMAN45.629.9
Q59EH9_HUMAN45.230
HRH3_HUMAN44.629.1
DRD2_RAT44.529
DRD2_MOUSE44.128.7
5HT1B_HUMAN43.228.6
HRH1_BOVIN4326.7
HRH1_HUMAN42.625.9
ACM1_HUMAN42.425.6
DRD3_HUMAN42.329.8
DRD4_MOUSE42.229.7
DRD4_HUMAN42.131.8
5HT5A_HUMAN41.826
ACM4_HUMAN41.525.1
Q9P2Q4_HUMAN39.625.3
5HT1F_HUMAN39.625.3
ACM2_HUMAN39.322.9
HRH4_HUMAN38.922.1
ACM3_HUMAN38.722.2
5HT1E_HUMAN38.225.3
ADRB1_HUMAN37.824.5
ADRB3_HUMAN37.526.1
ADA1A_HUMAN36.722.9
ADA1B_HUMAN36.222.5
ACM5_HUMAN36.221.3
Protein-Protein Interactions: