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Target Details

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Name:Alpha-1A adrenergic receptor
Uniprot name:ADA1A_HUMAN
Accession Numbers:A8K0I3 B0ZBD1 B0ZBD4 B0ZBD5 B0ZBD9 O60451 P35348 Q13675 Q13729 Q6RUJ4 Q6RUJ5 Q6RUJ7 Q6RUJ8 Q6RUJ9 Q9UD63
EC-Number:-
Organism:Homo sapiens
Human
PDB IDs:-
KEGG Pathways:show KEGG Pathways
Drugs:
NamePubChem IDSourceReferencesInteraction
1,2,3,4-Tetrahydro-2-naphthylamine34677BindingDB-show
1-(2-aminopropyl)-2H-indazol-6-one9834183BindingDB-show
2,5-Dimethoxyphenethylamine76632BindingDB-show
2-[4-[4-(3-methoxyphenyl)piperazin-1-yl]butyl]-4-methyl-1,2,4-triazine-3,511948707BindingDB-show
3-fluoro-4-(1-hydroxy-2-methylamino-ethyl)benzene-1,2-diol10420352BindingDB-show
3-Fluoronorepinephrine172745BindingDB-show
4-(2-Amino-1-hydroxyethyl)-5-fluoro-1,2-benzenediol1862BindingDB-show
5,6-Dimethoxy-1,2,3,4-tetrahydroisoquinoline3086052BindingDB-show
5-Methylurapidil5640BindingDB-show
7-Methoxy-1,2,3,4-tetrahydro-9H-pyrido[3,4-b]indole599482BindingDB-show
8-OH-Dpat1220BindingDB-show
A 238873039881BindingDB-show
A-3154566603710BindingDB-show
A314723038603BindingDB-show
A616034038180BindingDB-show
Abanoquil164089BindingDB-show
Acetophenazinum17676SuperTargetPMID 17606915show
AH11110A3386873BindingDB-show
alphuzosine2092BindingDB-show
alphuzosine2092DrugBank-show
alphuzosine2092SuperTargetPMID 17004180show
Amiodarone Hydrochloride2157DrugBank-show
AMIODARONE HYDROCHLORIDE441325DrugBank-show
Amiodarone Hydrochloride2157SuperTarget-show
AMIODARONE HYDROCHLORIDE441325SuperTarget-show
Amlodipine Benzenesulfonate2162BindingDB-show
benalfocin123981BindingDB-show
Benzenethanamine, 2-fluoro-2',4,5-trihydroxy-N-methyl-541604BindingDB-show
Benzylamphetamine2341DrugBank-show
Bethanidine6324770DrugBank-show
Bethanidine2368DrugBank-show
Bethanidine2368SuperTarget-show
Bethanidine6324770SuperTarget-show
BMY 7378 dihydrochloride2419BindingDB-show
Bromotopsentin183528BindingDB-show
C16H22ClNO122295BindingDB-show
Carvedilol2585DrugBank-show
Carvedilol2585SuperTarget-show
CHEBI:64392544275635BindingDB-show
CHEBI:64581444461506BindingDB-show
CHEMBL10004544329027BindingDB-show
CHEMBL10005244331174BindingDB-show
CHEMBL10087844331079BindingDB-show
CHEMBL10132210364538BindingDB-show
CHEMBL10157944331150BindingDB-show
CHEMBL10161010415038BindingDB-show
CHEMBL10173944331198BindingDB-show
CHEMBL10186944331277BindingDB-show
CHEMBL11391910615770BindingDB-show
CHEMBL11399010616819BindingDB-show
CHEMBL11538810357155BindingDB-show
CHEMBL1182818738380BindingDB-show
CHEMBL120629866614BindingDB-show
CHEMBL120915849862238BindingDB-show
CHEMBL1212718738382BindingDB-show
CHEMBL1220244267884BindingDB-show
CHEMBL12205044348140BindingDB-show
CHEMBL122361549865599BindingDB-show
CHEMBL122361649865600BindingDB-show
CHEMBL122361749865601BindingDB-show
CHEMBL122368049865639BindingDB-show
CHEMBL122368149865640BindingDB-show
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CHEMBL122368311511026BindingDB-show
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CHEMBL122379911668565BindingDB-show
CHEMBL122380011496213BindingDB-show
CHEMBL122380111655403BindingDB-show
CHEMBL122380211567620BindingDB-show
CHEMBL122385611568725BindingDB-show
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CHEMBL122385811711943BindingDB-show
CHEMBL122385911633992BindingDB-show
CHEMBL122452746869265BindingDB-show
CHEMBL12267144348045BindingDB-show
CHEMBL12301210603739BindingDB-show
CHEMBL12310244348164BindingDB-show
CHEMBL1231389839317BindingDB-show
CHEMBL12344810946567BindingDB-show
CHEMBL1236444267890BindingDB-show
CHEMBL12376944348163BindingDB-show
CHEMBL124132846915369BindingDB-show
CHEMBL124292344207909BindingDB-show
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CHEMBL1244029851803BindingDB-show
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CHEMBL49401610413283BindingDB-show
CHEMBL49415510073934BindingDB-show
CHEMBL49415644573932BindingDB-show
CHEMBL4985110743042BindingDB-show
CHEMBL49918044571840BindingDB-show
CHEMBL5008144294958BindingDB-show
CHEMBL50140444574133BindingDB-show
CHEMBL50192044574985BindingDB-show
CHEMBL50207844571887BindingDB-show
CHEMBL50326944574875BindingDB-show
CHEMBL5049044295133BindingDB-show
CHEMBL50541444574107BindingDB-show
CHEMBL50674444219718BindingDB-show
CHEMBL50736011539020BindingDB-show
CHEMBL50775544574938BindingDB-show
CHEMBL50808444574080BindingDB-show
CHEMBL50871211524225BindingDB-show
CHEMBL50935044574136BindingDB-show
CHEMBL51002344574137BindingDB-show
CHEMBL5101944295218BindingDB-show
CHEMBL51061344571845BindingDB-show
CHEMBL5107410048729BindingDB-show
CHEMBL51121144574135BindingDB-show
CHEMBL51141144574986BindingDB-show
CHEMBL51154244574008BindingDB-show
CHEMBL51157644574988BindingDB-show
CHEMBL51157744574989BindingDB-show
CHEMBL51174710391177BindingDB-show
CHEMBL51206244574045BindingDB-show
CHEMBL51228944574079BindingDB-show
CHEMBL51369144574074BindingDB-show
CHEMBL51387144574104BindingDB-show
CHEMBL51433344571937BindingDB-show
CHEMBL51547244582675BindingDB-show
CHEMBL51608844582676BindingDB-show
CHEMBL5187144294957BindingDB-show
CHEMBL51906711689687BindingDB-show
CHEMBL52011744571890BindingDB-show
CHEMBL52203744573821BindingDB-show
CHEMBL52369744573823BindingDB-show
CHEMBL52388244573820BindingDB-show
CHEMBL5563139908478BindingDB-show
CHEMBL5624844300166BindingDB-show
CHEMBL564389954092BindingDB-show
CHEMBL56555123027527BindingDB-show
CHEMBL56607515987265BindingDB-show
CHEMBL56779123027245BindingDB-show
CHEMBL56799345485062BindingDB-show
CHEMBL56840023027211BindingDB-show
CHEMBL5697444299973BindingDB-show
CHEMBL5754611211017BindingDB-show
CHEMBL5769144299835BindingDB-show
CHEMBL57790445484995BindingDB-show
CHEMBL57791223027411BindingDB-show
CHEMBL57817023027035BindingDB-show
CHEMBL58301445485061BindingDB-show
CHEMBL59544911957735BindingDB-show
CHEMBL5959010097317BindingDB-show
CHEMBL59606746225253BindingDB-show
CHEMBL6045244301572BindingDB-show
CHEMBL6164344301681BindingDB-show
CHEMBL6204510414908BindingDB-show
CHEMBL6224944301573BindingDB-show
CHEMBL6682344308654BindingDB-show
CHEMBL6755210506729BindingDB-show
CHEMBL6771318738385BindingDB-show
CHEMBL6804510768610BindingDB-show
CHEMBL6824144308466BindingDB-show
CHEMBL6856510578990BindingDB-show
CHEMBL6860110650843BindingDB-show
CHEMBL686999960311BindingDB-show
CHEMBL687469808529BindingDB-show
CHEMBL6891310770317BindingDB-show
CHEMBL6914310506673BindingDB-show
CHEMBL6924510507357BindingDB-show
CHEMBL6926410674564BindingDB-show
CHEMBL6933944308443BindingDB-show
CHEMBL6984818738386BindingDB-show
CHEMBL6996744309199BindingDB-show
CHEMBL7009510793720BindingDB-show
CHEMBL7017812134996BindingDB-show
CHEMBL7089210674055BindingDB-show
CHEMBL7091810473406BindingDB-show
CHEMBL7158010627003BindingDB-show
CHEMBL7580812134985BindingDB-show
CHEMBL7664312134987BindingDB-show
CHEMBL7686744316072BindingDB-show
CHEMBL7761810994812BindingDB-show
CHEMBL7790111014848BindingDB-show
CHEMBL7858411732516BindingDB-show
CHEMBL7867611081136BindingDB-show
CHEMBL7878511144555BindingDB-show
CHEMBL7887410005161BindingDB-show
CHEMBL7916110949698BindingDB-show
CHEMBL7953244462130BindingDB-show
CHEMBL7981744318075BindingDB-show
CHEMBL7994044460394BindingDB-show
CHEMBL7999044460522BindingDB-show
CHEMBL8003644318000BindingDB-show
CHEMBL8010944460477BindingDB-show
CHEMBL8012518738412BindingDB-show
CHEMBL8013210893672BindingDB-show
CHEMBL8026011123606BindingDB-show
CHEMBL8045811092254BindingDB-show
CHEMBL8059910917316BindingDB-show
CHEMBL8064110434440BindingDB-show
CHEMBL8073010074286BindingDB-show
CHEMBL8100619085926BindingDB-show
CHEMBL8109310811627BindingDB-show
CHEMBL8117319085894BindingDB-show
CHEMBL8148610928520BindingDB-show
CHEMBL8166144460423BindingDB-show
CHEMBL8205619085836BindingDB-show
CHEMBL8248012134991BindingDB-show
CHEMBL8287719085881BindingDB-show
CHEMBL8304119085839BindingDB-show
CHEMBL8322619085820BindingDB-show
CHEMBL8327219085876BindingDB-show
CHEMBL8334019085914BindingDB-show
CHEMBL8359219085829BindingDB-show
CHEMBL8379144460449BindingDB-show
CHEMBL8992710673657BindingDB-show
CHEMBL8996510839825BindingDB-show
CHEMBL9008644324405BindingDB-show
CHEMBL9018410792536BindingDB-show
CHEMBL9021010647424BindingDB-show
CHEMBL9045310792591BindingDB-show
CHEMBL9060610815240BindingDB-show
CHEMBL9065210576661BindingDB-show
CHEMBL9109110696866BindingDB-show
CHEMBL9112510529370BindingDB-show
CHEMBL9117910792152BindingDB-show
CHEMBL9140310697912BindingDB-show
CHEMBL9140510767264BindingDB-show
CHEMBL9222110106205BindingDB-show
CHEMBL9232810791844BindingDB-show
CHEMBL9352311800744BindingDB-show
CHEMBL9362310721564BindingDB-show
CHEMBL9384310626493BindingDB-show
CHEMBL9416710719222BindingDB-show
CHEMBL9418810767606BindingDB-show
CHEMBL9425910603030BindingDB-show
CHEMBL9525344328824BindingDB-show
CHEMBL9526344328739BindingDB-show
CHEMBL9529044328799BindingDB-show
CHEMBL9543444328738BindingDB-show
CHEMBL9554844328806BindingDB-show
CHEMBL9557844328801BindingDB-show
CHEMBL9573644328639BindingDB-show
CHEMBL9803844329028BindingDB-show
CHEMBL9806315853467BindingDB-show
CHEMBL9816710314056BindingDB-show
CHEMBL9816844330880BindingDB-show
CHEMBL982419845181BindingDB-show
CHEMBL984309847419BindingDB-show
CHEMBL9961444331090BindingDB-show
CHEMBL9986444329026BindingDB-show
Chlorohaloperidol173712BindingDB-show
Chlorperphenazine4748DrugBank-show
Chlorperphenazine4748SuperTarget-show
CID 1032078210599007BindingDB-show
CID 1055538310326069BindingDB-show
CID 1060355610393665BindingDB-show
CID 1062645310626453BindingDB-show
CID 1062645310578548BindingDB-show
CID 1062691111801214BindingDB-show
CID 1062691110626911BindingDB-show
CID 1062691110626910BindingDB-show
CID 1064948110744391BindingDB-show
CID 1064948110649481BindingDB-show
CID 1069857010745901BindingDB-show
CID 1069857010698570BindingDB-show
CID 1070662610084076BindingDB-show
CID 1072156810721568BindingDB-show
CID 1072156810602912BindingDB-show
CID 1079184310791843BindingDB-show
CID 1079184310815593BindingDB-show
CID 1079289710792897BindingDB-show
CID 1079289710792898BindingDB-show
CID 1081683210578926BindingDB-show
CID 1081683210816832BindingDB-show
CID 1083910510839105BindingDB-show
CID 1083910510839106BindingDB-show
CID 98307419830741BindingDB-show
CID 98307419891105BindingDB-show
CID 98749839874983BindingDB-show
CID 98946659894665BindingDB-show
CID 989466510674840BindingDB-show
CID 98948189894818BindingDB-show
CID 989528910029146BindingDB-show
CID 991451510369288BindingDB-show
CID 99158319915831BindingDB-show
CID 991583110507089BindingDB-show
CID 991583110626686BindingDB-show
CID 99165499916549BindingDB-show
Cornutamine8223DrugBank-show
Cornutamine8223SuperTarget-show
Corynanthine8969BindingDB-show
corynanthine92766BindingDB-show
Dapiprazole3033538DrugBank-show
Dapiprazole3033538SuperTarget-show
Debrisochinum2966DrugBank-show
Desoxynorephedrine3007SuperTarget-show
Dibencycladine4011DrugBank-show
Dibencycladine4011SuperTarget-show
Doxazosin3157BindingDB-show
Doxazosin3157DrugBank-show
doxazosin6604102DrugBank-show
Doxazosin3157SuperTarget2 PMIDsshow
doxazosin6604102SuperTarget2 PMIDsshow
Droxidopa443940DrugBank-show
Droxidopa92974DrugBank-show
Epinastine3241DrugBank-show
Epinastine3241SuperTarget-show
FLUPENTHIXOL5281881SuperTarget-show
Flupenthixole17012DrugBank-show
Guanadrel38521DrugBank-show
Guanethidine3518DrugBank-show
Guanfacine Monohydrochloride3519SuperTarget-show
Hydroxynorephedrine5906DrugBank-show
Hydroxynorephedrine5906SuperTarget-show
Ifenprodil [DCF:INN]11198145BindingDB-show
Indoramine33625BindingDB-show
Indoramine33625SuperTargetPMID 008925876show
Ipsapironum56971BindingDB-show
Isopromethazine4927DrugBank-show
Isopromethazine4927SuperTarget-show
Labetalol hydrochloride3869DrugBank-show
Labetalol hydrochloride3869SuperTarget-show
Leucoharmine5280953BindingDB-show
Levonorepinephrine439260DrugBank-show
Levonorepinephrine5814DrugBank-show
Lisdexamfetamine dimesylate11597697DrugBank-show
MAZAPERTINE60820BindingDB-show
Mediatensyl5639SuperTargetPMID 007904564show
Mephenmetrazine12460DrugBank-show
Mephenterdrinum3677DrugBank-show
Metasynephrine6041DrugBank-show
Metasynephrine6041SuperTarget2 PMIDsshow
Methotrimeprazine72287DrugBank-show
Methylaminoethanolcatechol5816BindingDB-show
Methylaminoethanolcatechol5816DrugBank-show
Methylaminoethanolcatechol5816SuperTargetPMID 7916000show
Methylamphetamine10836DrugBank-show
Methylnorethindrone13109DrugBank-show
Methylnorethindrone4542DrugBank-show
midodrine hydrochloride4195DrugBank-show
midodrine hydrochloride4195SuperTarget-show
MLS0001052271376848BindingDB-show
Naftopidil dihydrochloride4418BindingDB-show
Nantenine197001BindingDB-show
NCGC00015604-016603904BindingDB-show
NCGC00024648-014431BindingDB-show
NCGC00165717-019934033BindingDB-show
Nefazodone Hydrochloride4449DrugBank-show
NEFAZODONE HYDROCHLORIDE54911DrugBank-show
Nefazodone Hydrochloride4449SuperTarget-show
NEFAZODONE HYDROCHLORIDE54911SuperTarget-show
Nicotergoline34040DrugBank-show
Nicotergoline34040SuperTarget-show
NIGULDIPINE60602BindingDB-show
Nilutamide4493DrugBank-show
Nilutamide4493SuperTarget-show
NITD60944469321BindingDB-show
norepinephrine951BindingDB-show
Nortopsentin A179268BindingDB-show
Nortopsentin B456387BindingDB-show
Nortopsentin C456386BindingDB-show
Oximetazolinum4636DrugBank-show
Oximetazolinum4636SuperTargetPMID 011774707show
para-methoxyamphetamine31721DrugBank-show
PDSP1_000858126225BindingDB-show
PDSP2_0004526918097BindingDB-show
Phenothiazine4926DrugBank-show
Phenothiazine4926SuperTarget-show
Phenoxybenzamine4768DrugBank-show
Phenoxybenzamine4768SuperTarget-show
Phentolamine Methanesulfonate5775BindingDB-show
Phentolamine Methanesulfonate5775SuperTargetPMID 008768700show
Phenylisopropylamine5826DrugBank-show
Phenylmethylimidazoline5504DrugBank-show
Phenylmethylimidazoline5504SuperTarget-show
Phenylpropanolamine10297BindingDB-show
Phenylpropanolamine26934DrugBank-show
Phenylpropanolamine10297DrugBank-show
Phenylpropanolamine26934SuperTarget-show
Phenylpropanolamine10297SuperTarget-show
Piperocyanomazine4747DrugBank-show
Propionylpromethazine4940DrugBank-show
Propionylpromethazine4940SuperTarget-show
PSEUDOEPHEDRINE7028DrugBank-show
Pseudoephedrine9294DrugBank-show
PSEUDOEPHEDRINE7028SuperTarget-show
Pseudoephedrine9294SuperTarget-show
Pseudomethoxamine6082BindingDB-show
Pseudomethoxamine6082DrugBank-show
Pseudomethoxamine6082SuperTarget-show
Racepinephrine838BindingDB-show
Rauwolscine643606BindingDB-show
Rec 15-2739148842BindingDB-show
Risperidonum5073BindingDB-show
Risperidonum5073DrugBank-show
Risperidonum5073SuperTarget-show
RS170533894573BindingDB-show
sertindole hydrochloride60149DrugBank-show
Silodosin5312125BindingDB-show
SNAP-39829911698643BindingDB-show
SNAP-515044390749BindingDB-show
SNAP-794111520239BindingDB-show
SNAP-9484716756754BindingDB-show
SNAP50895311437BindingDB-show
Spiroperidol5265BindingDB-show
ST-105943260BindingDB-show
TAMSULOSIN HYDROCHLORIDE129211BindingDB-show
TAMSULOSIN HYDROCHLORIDE129211DrugBank-show
TAMSULOSIN HYDROCHLORIDE5362376DrugBank-show
TAMSULOSIN HYDROCHLORIDE129211SuperTarget-show
TAMSULOSIN HYDROCHLORIDE5362376SuperTarget-show
Terazosin hydrochloride4893BindingDB-show
Terazosin hydrochloride5401BindingDB-show
Terazosin hydrochloride4893DrugBank-show
Terazosin hydrochloride5401DrugBank-show
Terazosin hydrochloride4893SuperTargetPMID 007705452show
Terazosin hydrochloride5401SuperTargetPMID 007705452show
Terazosin hydrochloride4893SuperTarget-show
Thiethylpipezazine5440SuperTarget-show
Thioridazine Hydrochloride5452DrugBank-show
Thioridazine Hydrochloride5452SuperTarget-show
Tocris-0928609483BindingDB-show
Tocris-13253567002BindingDB-show
Topsentin72457BindingDB-show
Trazodone Hydrochloride5533DrugBank-show
Trazodone hydrochloride62935DrugBank-show
Trazodone Hydrochloride5533SuperTarget-show
Trazodone hydrochloride62935SuperTarget-show
Trifluoromethylperazine5566DrugBank-show
Trifluoromethylperazine5566SuperTarget-show
Tyrphostin B565328775BindingDB-show
WB41015685BindingDB-show
Xylomethazoline5709BindingDB-show
Ziprasidone hydrochloride60854DrugBank-show
Ziprasidone hydrochloride219099DrugBank-show
Ziprasidone hydrochloride60854SuperTarget-show
Ziprasidone hydrochloride219099SuperTarget-show
Synonyms:
Alpha 1A-adrenoceptor
Alpha 1A-adrenoreceptor
Alpha-1A adrenergic receptor
Alpha-1C adrenergic receptor
Alpha-adrenergic receptor 1c
Similar targets:
Uniprot name% Sequence similarity% Sequence identity
ADA1B_HUMAN57.644.7
ADA1D_HUMAN53.240
DRD1_HUMAN49.831.3
5HT6R_HUMAN45.927.5
Q7Z5R9_HUMAN45.928.8
ADRB2_HUMAN45.828.1
Q5VX04_HUMAN44.628.4
Q712M9_HUMAN42.927.4
ADRB3_HUMAN41.827.1
5HT2B_HUMAN41.625.2
Q5VX03_HUMAN41.426.4
ADRB1_HUMAN40.226.4
5HT1D_HUMAN4025.8
5HT2A_HUMAN4023.9
HRH2_HUMAN39.926.9
5HT1F_HUMAN39.826.6
Q9P2Q4_HUMAN39.826.8
DRD5_HUMAN39.825.7
AA2AR_HUMAN39.625.3
5HT7R_HUMAN39.425.7
5HT1A_HUMAN39.325.1
Q5ZGX3_HUMAN39.325.1
5HT1B_HUMAN39.226.2
5HT4R_HUMAN39.125.9
Q546Q1_HUMAN39.125.9
5HT5A_HUMAN38.724.8
5HT1E_HUMAN38.223.9
ADA2A_HUMAN3824.7
Q684M0_HUMAN37.924.4
TAAR1_HUMAN37.922.8
Protein-Protein Interactions: