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Target Details

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Name:Activin receptor type-1
Uniprot name:ACVR1_HUMAN
Accession Numbers:Q04771
EC-Number:2.7.11.30
Organism:Homo sapiens
Human
PDB IDs:3H9R
KEGG Pathways:show KEGG Pathways
Drugs:
NamePubChem IDSourceReferencesInteraction
3-((3R,4R)-4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperi9926791BindingDB-show
ABT-86911485656BindingDB-show
Adenosintriphosphorsaeure5957DrugBank-show
AMG 70611667893BindingDB-show
AST-48711409972BindingDB-show
Canertinib156414BindingDB-show
CHEBI:1043465459219BindingDB-show
CHEBI:25992444329707BindingDB-show
CHEBI:66834345481533BindingDB-show
CHEBI:66834445481534BindingDB-show
CHEMBL124070352945601BindingDB-show
CHIR-26511656518BindingDB-show
CP-7247149874913BindingDB-show
Dasatinib3062316BindingDB-show
Doramapimod156422BindingDB-show
Erlotinib176870BindingDB-show
Gefitinib123631BindingDB-show
GW-258011617559BindingDB-show
Imatinib Methansulfonate5291BindingDB-show
Lapatinib ditosylate208908BindingDB-show
Lestaurtinib126565BindingDB-show
MLN805411712649BindingDB-show
Pazopanib10113978BindingDB-show
PI-1039884685BindingDB-show
PKC-4129829523BindingDB-show
Roscovitine160355BindingDB-show
Ruboxistaurin153999BindingDB-show
RWJ-3872525330790BindingDB-show
S1018_Selleck9977819BindingDB-show
S1147_Selleck16007391BindingDB-show
S1526_Selleck24889392BindingDB-show
SB 2021905353940BindingDB-show
SB-4315424521392BindingDB-show
SNS-0323025986BindingDB-show
sorafenibum216239BindingDB-show
staurosporine44299148BindingDB-show
SU-1481310138259BindingDB-show
Sunitinib5329102BindingDB-show
Tandutinib3038522BindingDB-show
Vandetanib3081361BindingDB-show
Vatalanib151194BindingDB-show
VX-6805494449BindingDB-show
VX-7453038525BindingDB-show
Synonyms:
Activin receptor type I
Activin receptor type-1
Activin receptor-like kinase 2
ACTR-I
ALK-2
Serine/threonine-protein kinase receptor R1
SKR1
TGF-B superfamily receptor type I
TSR-I
Similar targets:
Uniprot name% Sequence similarity% Sequence identity
ACVL1_HUMAN70.358.8
ACV1B_HUMAN62.548.1
TGFR1_RAT59.947.6
TGFR2_HUMAN44.127
AMHR2_HUMAN39.825.4
ILK_CAVPO36.521.3
CSK_HUMAN36.321.1
STK6_HUMAN3419.2
LCK_HUMAN33.420.3
SYEM_HUMAN33.217.2
ZAP70_HUMAN32.117.1
SRC_RSVSE31.920.7
HCK_HUMAN31.619.6
SUCB1_HUMAN31.518.9
PAK1_CAEEL31.518.3
CLPX_HELPY31.216.5
SPTC1_HUMAN31.215.7
YES_HUMAN3120.1
PGH1_RAT30.617.9
HEXB_HUMAN30.616.9
Q5DT00_HUMAN30.617.6
UD14_HUMAN30.617.6
FKBP5_HUMAN30.516.8
Q53GX4_HUMAN30.516.8
Q5TGM6_HUMAN30.516.8
P4HTM_HUMAN30.517.1
SRC_HUMAN30.419.9
UD15_HUMAN30.217.5
Q5DSZ9_HUMAN30.217.5
HEM6_HUMAN30.116.4
Protein-Protein Interactions: