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Target Details

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Name:Serine/threonine-protein kinase receptor R3
Uniprot name:ACVL1_HUMAN
Accession Numbers:A6NGA8 P37023
EC-Number:2.7.11.30
Organism:Homo sapiens
Human
PDB IDs:-
KEGG Pathways:show KEGG Pathways
Drugs:
NamePubChem IDSourceReferencesInteraction
3-((3R,4R)-4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperi9926791BindingDB-show
ABT-86911485656BindingDB-show
Adenosintriphosphorsaeure5957DrugBank-show
AMG 70611667893BindingDB-show
AST-48711409972BindingDB-show
Canertinib156414BindingDB-show
CHEBI:1043465459219BindingDB-show
CHEBI:25992444329707BindingDB-show
CHEBI:66834345481533BindingDB-show
CHEBI:66834445481534BindingDB-show
CHEMBL124070352945601BindingDB-show
CHIR-26511656518BindingDB-show
CP-7247149874913BindingDB-show
Dasatinib3062316BindingDB-show
Doramapimod156422BindingDB-show
Erlotinib176870BindingDB-show
Gefitinib123631BindingDB-show
GW-258011617559BindingDB-show
Imatinib Methansulfonate5291BindingDB-show
Lapatinib ditosylate208908BindingDB-show
Lestaurtinib126565BindingDB-show
MLN805411712649BindingDB-show
Pazopanib10113978BindingDB-show
PI-1039884685BindingDB-show
PKC-4129829523BindingDB-show
Roscovitine160355BindingDB-show
Ruboxistaurin153999BindingDB-show
RWJ-3872525330790BindingDB-show
S1018_Selleck9977819BindingDB-show
S1147_Selleck16007391BindingDB-show
S1526_Selleck24889392BindingDB-show
SB 2021905353940BindingDB-show
SB-4315424521392BindingDB-show
SNS-0323025986BindingDB-show
sorafenibum216239BindingDB-show
staurosporine44299148BindingDB-show
SU-1481310138259BindingDB-show
Sunitinib5329102BindingDB-show
Tandutinib3038522BindingDB-show
Vandetanib3081361BindingDB-show
Vatalanib151194BindingDB-show
VX-6805494449BindingDB-show
VX-7453038525BindingDB-show
Synonyms:
Activin receptor-like kinase 1
ALK-1
Serine/threonine-protein kinase receptor R3
SKR3
TGF-B superfamily receptor type I
TSR-I
Similar targets:
Uniprot name% Sequence similarity% Sequence identity
ACVR1_HUMAN70.358.8
ACV1B_HUMAN59.146.5
TGFR1_RAT58.847.1
TGFR2_HUMAN39.325.5
AMHR2_HUMAN38.625.7
ILK_CAVPO34.219.6
SRC_RAT3420.2
SRC_HUMAN32.519.5
LCK_HUMAN32.419.6
ARAF_HUMAN31.620.1
HCK_HUMAN31.418.9
STK6_HUMAN31.418.9
CSK_HUMAN31.418.6
A5DGG1_PICGU3117.7
CSAD_HUMAN30.618.2
BPI_HUMAN30.618.4
TRFL_HORSE30.418.5
AOR_PYRFU30.317.6
CDK15_HUMAN30.117.4
AKT1_HUMAN30.117.5
UROK_HUMAN29.918.8
AMYP_HUMAN29.917.8
Q8GN86_9BURK29.818
GALNS_HUMAN29.819.9
MYLK2_RAT29.716.9
Q4VA93_MOUSE29.617.7
CP2A7_HUMAN29.618.4
IGHE_HUMAN29.617.5
MP2K2_HUMAN29.417.4
ITK_HUMAN29.217.8
Protein-Protein Interactions: