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Target Details

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Name:Activin receptor type-1B
Uniprot name:ACV1B_HUMAN
Accession Numbers:P36896 Q15479 Q15480 Q15481 Q15482
EC-Number:2.7.11.30
Organism:Homo sapiens
Human
PDB IDs:-
KEGG Pathways:show KEGG Pathways
Drugs:
NamePubChem IDSourceReferencesInteraction
3-((3R,4R)-4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperi9926791BindingDB-show
ABT-86911485656BindingDB-show
Adenosintriphosphorsaeure5957DrugBank-show
AMG 70611667893BindingDB-show
AST-48711409972BindingDB-show
Canertinib156414BindingDB-show
CHEBI:1043465459219BindingDB-show
CHEBI:25992444329707BindingDB-show
CHEBI:66834345481533BindingDB-show
CHEBI:66834445481534BindingDB-show
CHEMBL124070352945601BindingDB-show
CHIR-26511656518BindingDB-show
CP-7247149874913BindingDB-show
Dasatinib3062316BindingDB-show
Doramapimod156422BindingDB-show
Erlotinib176870BindingDB-show
Gefitinib123631BindingDB-show
GW-258011617559BindingDB-show
Imatinib Methansulfonate5291BindingDB-show
Lapatinib ditosylate208908BindingDB-show
Lestaurtinib126565BindingDB-show
MLN805411712649BindingDB-show
Pazopanib10113978BindingDB-show
PI-1039884685BindingDB-show
PKC-4129829523BindingDB-show
Roscovitine160355BindingDB-show
Ruboxistaurin153999BindingDB-show
RWJ-3872525330790BindingDB-show
S1018_Selleck9977819BindingDB-show
S1147_Selleck16007391BindingDB-show
S1526_Selleck24889392BindingDB-show
SB 2021905353940BindingDB-show
SB-4315424521392BindingDB-show
SNS-0323025986BindingDB-show
sorafenibum216239BindingDB-show
staurosporine44299148BindingDB-show
SU-1481310138259BindingDB-show
Sunitinib5329102BindingDB-show
Tandutinib3038522BindingDB-show
Vandetanib3081361BindingDB-show
Vatalanib151194BindingDB-show
VX-6805494449BindingDB-show
VX-7453038525BindingDB-show
Synonyms:
Activin receptor type-1B
Activin receptor-like kinase 4
ACTR-IB
ALK-4
Serine/threonine-protein kinase receptor R2
SKR2
Similar targets:
Uniprot name% Sequence similarity% Sequence identity
TGFR1_RAT80.969.9
ACVR1_HUMAN62.548.1
ACVL1_HUMAN59.146.5
TGFR2_HUMAN4226.5
AMHR2_HUMAN38.724.4
CSK_HUMAN36.820.5
ILK_CAVPO34.917.8
HCK_HUMAN3420.3
SRC_RAT32.419.1
YES_HUMAN32.118.2
STK6_HUMAN3218.2
RAF1_RAT31.919.9
RAF1_MOUSE31.919.9
RAF1_HUMAN31.319.1
DLDH_PEA31.316.9
PDE9A_HUMAN31.319.5
SRC_RSVSE3118.5
KPEL_DROME30.819.7
Q8WUQ4_HUMAN30.717.6
UD16_HUMAN30.717.6
LCK_HUMAN30.719.3
Q5DSZ8_HUMAN30.717.6
Q9ZPL5_TOBAC30.617.1
ERR3_RAT30.417.8
ERR3_HUMAN30.417.8
ERR3_MOUSE30.417.8
MP2K4_HUMAN30.317.2
SC6A1_HUMAN30.216.7
VDR_RAT30.218.2
Q8T8E9_9TRYP29.918.9
Protein-Protein Interactions: