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Target Details

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Name:Activated CDC42 kinase 1
Uniprot name:ACK1_HUMAN
Accession Numbers:Q07912 Q6ZMQ0 Q8N6U7 Q96H59
EC-Number:2.7.10.2
Organism:Homo sapiens
Human
PDB IDs:1CF4 1U46 1U4D 1U54 3EQP 3EQR
KEGG Pathways:-
Drugs:
NamePubChem IDSourceReferencesInteraction
3-((3R,4R)-4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperi9926791BindingDB-show
ABT-86911485656BindingDB-show
Adenosintriphosphorsaeure5957DrugBank-show
AMG 70611667893BindingDB-show
AST-48711409972BindingDB-show
Bosutinib5328940BindingDB-show
Canertinib156414BindingDB-show
CHEBI:1043465459219BindingDB-show
CHEBI:25992444329707BindingDB-show
CHEBI:4043217756743BindingDB-show
CHEBI:66834345481533BindingDB-show
CHEBI:66834445481534BindingDB-show
CHEMBL24706844438314BindingDB-show
CHEMBL24707011501591BindingDB-show
CHEMBL24746811684933BindingDB-show
CHEMBL24746911562553BindingDB-show
CHEMBL24747944438318BindingDB-show
CHEMBL24748011677453BindingDB-show
CHEMBL24766711540659BindingDB-show
CHEMBL24767744438320BindingDB-show
CHEMBL24786611626406BindingDB-show
CHEMBL24787811656437BindingDB-show
CHEMBL24788011648745BindingDB-show
CHEMBL24807911626947BindingDB-show
CHEMBL24808011620266BindingDB-show
CHEMBL24808111634876BindingDB-show
CHEMBL24828611554885BindingDB-show
CHEMBL39449011678465BindingDB-show
CHEMBL39900811626681BindingDB-show
CHEMBL39921211519350BindingDB-show
CHEMBL45091816048979BindingDB-show
CHEMBL45833325154877BindingDB-show
CHEMBL45904444562721BindingDB-show
CHEMBL45922044562722BindingDB-show
CHEMBL46115816048826BindingDB-show
CHEMBL46115925154878BindingDB-show
CHEMBL46133744562670BindingDB-show
CHEMBL46218944562723BindingDB-show
CHEMBL46236444562724BindingDB-show
CHEMBL46236544562725BindingDB-show
CHEMBL47239215965424BindingDB-show
CHEMBL47239316049186BindingDB-show
CHEMBL48704816049188BindingDB-show
CHEMBL48705444563041BindingDB-show
CHEMBL48705516048825BindingDB-show
CHEMBL48724144563040BindingDB-show
CHEMBL48724244562974BindingDB-show
CHEMBL48724344562975BindingDB-show
CHEMBL48789644563015BindingDB-show
CHEMBL48789744563016BindingDB-show
CHEMBL48806144563018BindingDB-show
CHEMBL48806244563019BindingDB-show
CHEMBL50215625263033BindingDB-show
CHEMBL50433116049260BindingDB-show
CHEMBL51491916049258BindingDB-show
CHEMBL51666016049187BindingDB-show
CHEMBL51882216048974BindingDB-show
CHEMBL51991644563020BindingDB-show
CHEMBL52040344563017BindingDB-show
CHEMBL52137916049257BindingDB-show
CHEMBL52138116048823BindingDB-show
CHEMBL59775446233287BindingDB-show
CHEMBL59922445139989BindingDB-show
CHEMBL59942845139991BindingDB-show
CHIR-26511656518BindingDB-show
CP-7247149874913BindingDB-show
Dasatinib3062316BindingDB-show
DEBROMOHYMENIALDISINE5288032DrugBank-show
Doramapimod156422BindingDB-show
Erlotinib176870BindingDB-show
Gefitinib123631BindingDB-show
GW-258011617559BindingDB-show
Imatinib Methansulfonate5291BindingDB-show
Lapatinib ditosylate208908BindingDB-show
MLN805411712649BindingDB-show
Pazopanib10113978BindingDB-show
Pelitinib6445562BindingDB-show
PI-1039884685BindingDB-show
Roscovitine160355BindingDB-show
Ruboxistaurin153999BindingDB-show
RWJ-3872525330790BindingDB-show
S1018_Selleck9977819BindingDB-show
S1147_Selleck16007391BindingDB-show
SB 2021905353940BindingDB-show
SB-4315424521392BindingDB-show
SNS-0323025986BindingDB-show
sorafenibum216239BindingDB-show
STAUROSPORINE44259BindingDB-show
staurosporine44299148BindingDB-show
SU-1481310138259BindingDB-show
Sunitinib5329102BindingDB-show
Tandutinib3038522BindingDB-show
Vandetanib3081361BindingDB-show
Vatalanib151194BindingDB-show
VX-6805494449BindingDB-show
VX-7453038525BindingDB-show
Synonyms:
ACK-1
Activated CDC42 kinase 1
Tyrosine kinase non-receptor protein 2
Similar targets:
Uniprot name% Sequence similarity% Sequence identity
Q59F19_HUMAN34.623.2
ABL1_HUMAN33.922.3
Q59FK4_HUMAN32.921.7
ABL2_HUMAN30.520.3
ABL_MLVAB30.522.1
Q9H4D1_HUMAN27.718.1
BGAL_ECOLI27.718
PLCL1_HUMAN27.416.3
CAPP_ECOLI27.317.2
SYI_THET826.917.6
FAK1_MOUSE26.817.7
Q26964_TRYCR26.817.8
VGP3_EBVP326.817.7
PUTA_ECOLI26.616.8
NOS3_MOUSE26.416.8
EXO1_HUMAN26.316.4
NCOAT_HUMAN25.816.6
Q0VQP0_ALCBS25.716.3
TAOK2_RAT25.718.4
BCA_STRA125.616.5
A0JN73_BOVIN25.416.4
ITA2B_HUMAN25.417.2
OGFR_HUMAN25.317.4
HDAC6_HUMAN25.216
Protein-Protein Interactions: