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Target Details

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Name:Acetylcholinesterase
Uniprot name:ACES_TORCA
Accession Numbers:P04058
EC-Number:3.1.1.7
Organism:Pacific electric ray
Torpedo californica
PDB IDs:1ACJ 1ACL 1AMN 1AX9 1CFJ 1DX6 1E3Q 1E66 1EA5 1EEA 1EVE 1FSS 1GPK 1GPN 1GQR 1GQS 1H22 1H23 1HBJ 1JGA 1JGB 1JJB 1OCE 1ODC 1QID 1QIE 1QIF 1QIG 1QIH 1QII 1QIJ 1QIK 1QIM 1QTI 1SOM 1U65 1UT6 1VOT 1VXO 1VXR 1W4L 1W6R 1W75 1W76 1ZGB 1ZGC 2ACE 2ACK 2BAG 2C4H 2C58 2C5F 2C5G 2CEK 2CKM 2CMF 2DFP 2J3D 2J3Q 2J4F 2V96 2V97 2V98 2VA9 2VJA 2VJB 2VJC 2VJD 2VQ6 2VT6 2VT7 2W6C 2WFZ 2WG0 2WG1 3ACE 4ACE
KEGG Pathways:-
Drugs:
NamePubChem IDSourceReferencesInteraction
(+/-)-Huperzine A1253BindingDB-show
(-)-Huperzine B23645296BindingDB-show
(2-(Ethylthio)ethyl)trimethylammonium iodide3026640BindingDB-show
(R)-TACRINE(10)-HUPYRIDONE5326966DrugBank-show
(S)-TACRINE(10)-HUPYRIDONE5326967DrugBank-show
1-DEOXY-1-THIO-HEPTAETHYLENE GLYCOL446506DrugBank-show
10-(2-(Diethylamino)propionyl)phenothiazine1403BindingDB-show
2-(N-morpholiniumyl)ethanesulfonate4478249DrugBank-show
3-(2,5-dioxopyrrolidin-1-yl)benzoic acid692331BindingDB-show
3-CHLORO-9-ETHYL-6,7,8,9,10,11-HEXAHYDRO-7,11-METHANOCYCLOOCTA[B]QUINOLIN-12-AMINE5288588DrugBank-show
3-Nitrophenyltrimethylammonium iodide3026752BindingDB-show
3-Trifluoroacetylbenzyl bromide10858440BindingDB-show
3-[(1S)-1-(DIMETHYLAMINO)ETHYL]PHENOL445892DrugBank-show
3-[1-(dimethylamino)ethyl]phenol409441BindingDB-show
4-Ketoamyltrimethylammonium iodide91419BindingDB-show
523461_ALDRICH11098210BindingDB-show
8-(1,2,3,4-tetrahydroacridin-10-ium-9-ylamino)octylazanium5287586DrugBank-show
AC1L9MQF449106BindingDB-show
AMAB76358BindingDB-show
Aminoquinoline 11a11084977BindingDB-show
Aminoquinoline 13a10991936BindingDB-show
Aminoquinoline 13b10937622BindingDB-show
Aminoquinoline 1710992013BindingDB-show
Aminoquinoline 1811098484BindingDB-show
Aminoquinoline 23a11132948BindingDB-show
Aminoquinoline 23b10982444BindingDB-show
Aminoquinoline 23c11122302BindingDB-show
Aminoquinoline 2710024412BindingDB-show
Aminoquinoline 2911002723BindingDB-show
Aminoquinoline 8a11118402BindingDB-show
Aminoquinoline 9a10987418BindingDB-show
BPTMA151145BindingDB-show
Butyrylcholine iodide17232BindingDB-show
Butyrylthiocholine iodide74630BindingDB-show
CHEBI:34550144364796BindingDB-show
CHEBI:34578244364858BindingDB-show
CHEBI:46145944417592BindingDB-show
CHEBI:64837044376846BindingDB-show
CHEBI:64837344377236BindingDB-show
CHEBI:64840144376668BindingDB-show
CHEBI:64841844376848BindingDB-show
CHEBI:64844044376862BindingDB-show
CHEBI:64844944376836BindingDB-show
CHEBI:64859644376912BindingDB-show
CHEBI:65247244376869BindingDB-show
CHEBI:65250744376677BindingDB-show
CHEBI:65251444376699BindingDB-show
CHEBI:65255344376937BindingDB-show
CHEBI:65256344376837BindingDB-show
CHEBI:65259144376974BindingDB-show
CHEBI:65259944376669BindingDB-show
CHEBI:65349644376863BindingDB-show
CHEBI:65366644435834BindingDB-show
CHEBI:65366645266173BindingDB-show
CHEBI:65366744435836BindingDB-show
CHEBI:65366745266174BindingDB-show
CHEBI:65366844435837BindingDB-show
CHEBI:65366845266175BindingDB-show
CHEBI:65366944435839BindingDB-show
CHEBI:65366945266176BindingDB-show
CHEBI:65374644435833BindingDB-show
CHEBI:65374645266243BindingDB-show
CHEBI:65374844435835BindingDB-show
CHEBI:65374845266245BindingDB-show
CHEBI:654012360200BindingDB-show
CHEBI:65401745266416BindingDB-show
CHEMBL10750410950066BindingDB-show
CHEMBL10887211759669BindingDB-show
CHEMBL10910511732020BindingDB-show
CHEMBL14597344364801BindingDB-show
CHEMBL14620544364791BindingDB-show
CHEMBL14649444364803BindingDB-show
CHEMBL14667444364800BindingDB-show
CHEMBL14853114157084BindingDB-show
CHEMBL14890744364790BindingDB-show
CHEMBL14893944364927BindingDB-show
CHEMBL23259044431324BindingDB-show
CHEMBL23554823635499BindingDB-show
CHEMBL23556444431335BindingDB-show
CHEMBL23556516739268BindingDB-show
CHEMBL32299410906285BindingDB-show
CHEMBL34253744364859BindingDB-show
CHEMBL34256444364895BindingDB-show
CHEMBL35696944364799BindingDB-show
CHEMBL35698210066129BindingDB-show
CHEMBL35745115209645BindingDB-show
CHEMBL39490144431325BindingDB-show
CHEMBL39694116384021BindingDB-show
CHEMBL43981444364896BindingDB-show
CHEMBL45332644561204BindingDB-show
CHEMBL51947510429940BindingDB-show
CHEMBL53835845266444BindingDB-show
CHEMBL53860223645743BindingDB-show
CHEMBL53860323645749BindingDB-show
CHEMBL53962323645736BindingDB-show
CHEMBL53962523645751BindingDB-show
CHEMBL53987323645745BindingDB-show
CHEMBL53987523645741BindingDB-show
CHEMBL54166323645734BindingDB-show
CHEMBL55660323645747BindingDB-show
CHEMBL55840923645739BindingDB-show
CHEMBL59393346226600BindingDB-show
CHEMBL59418646226629BindingDB-show
CHEMBL59418746226630BindingDB-show
CHEMBL59487046226577BindingDB-show
CHEMBL59511446226620BindingDB-show
CHEMBL59511546226660BindingDB-show
CHEMBL59623646226601BindingDB-show
CHEMBL59645746226644BindingDB-show
CHEMBL60447846226659BindingDB-show
CHEMBL60530346226578BindingDB-show
CHEMBL60634846226589BindingDB-show
CHEMBL60637246226643BindingDB-show
CHEMBL60653846226649BindingDB-show
Chlorcholinchlorid13836BindingDB-show
Chloroacetylcholine187DrugBank-show
Chloroacetylcholine187SuperTarget-show
Choline ethyl ether85369BindingDB-show
CID 1116516911199388BindingDB-show
CIS-2,6-DIMETHYLMORPHOLINOOCTYLCARBAMYLESEROLINE5288799DrugBank-show
DB022265289507BindingDB-show
DB030055289508BindingDB-show
Diisopropylphosphorofluoridate5936BindingDB-show
Donepezil3152BindingDB-show
Donepezil hydrochloride5741BindingDB-show
E10445974BindingDB-show
E12445975BindingDB-show
EINECS 230-513-73014543BindingDB-show
Exelon9952812BindingDB-show
FBQ1723BindingDB-show
galanthamine deriv. 13d23645192BindingDB-show
galanthamine deriv. 13e23645194BindingDB-show
galanthamine deriv. 13f23645196BindingDB-show
galanthamine deriv. 1423644645BindingDB-show
galanthamine deriv. 3b23645165BindingDB-show
galanthamine deriv. 3c23645166BindingDB-show
galanthamine deriv. 3e23645167BindingDB-show
galanthamine deriv. 3f23644635BindingDB-show
galanthamine deriv. 4b23645168BindingDB-show
galanthamine deriv. 4c23645170BindingDB-show
galanthamine deriv. 4d10054455BindingDB-show
galanthamine deriv. 4e11764693BindingDB-show
galanthamine deriv. 4f23644636BindingDB-show
galanthamine deriv. 5a23645172BindingDB-show
galanthamine deriv. 5c23645174BindingDB-show
galanthamine deriv. 5d23645176BindingDB-show
galanthamine deriv. 5e23645178BindingDB-show
galanthamine deriv. 5f23644638BindingDB-show
galanthamine deriv. 7b23645180BindingDB-show
galanthamine deriv. 7d23645181BindingDB-show
galanthamine deriv. 7e23645182BindingDB-show
galanthamine deriv. 7f23644640BindingDB-show
galanthamine deriv. 8b23645183BindingDB-show
galanthamine deriv. 8d23645185BindingDB-show
galanthamine deriv. 8e23645186BindingDB-show
galanthamine deriv. 8f23644641BindingDB-show
galanthamine deriv. 9d23645188BindingDB-show
galanthamine deriv. 9e23645190BindingDB-show
galanthamine deriv. 9f23644643BindingDB-show
GALANTHAMINE DERIVATIVE5288394BindingDB-show
GALANTHAMINE DERIVATIVE5288394DrugBank-show
Galanthamine derivative 423645164BindingDB-show
Galanthaminum9651BindingDB-show
Galanthaminum9651DrugBank-show
Gallamine Triiodoethylate67425BindingDB-show
Ganstigmine (CHF-2819)23645738BindingDB-show
Geneserine (N-oxide)23645732BindingDB-show
Hexyltrimethylammonium iodide84773BindingDB-show
HUPERAINE A854026BindingDB-show
HUPERAINE A6323377DrugBank-show
Huperzine A5912039BindingDB-show
huperzine b5462442BindingDB-show
IFLab1_001254757562BindingDB-show
irinotecan hydrochloride60838BindingDB-show
Jodoetano87300BindingDB-show
M-(N,N,N-TRIMETHYLAMMONIO)-2,2,2-TRIFLUORO-1,1-DIHYDROXYETHYLBENZENE3991DrugBank-show
METHYLPHOSPHINIC ACID6369390DrugBank-show
N-acetyl-alpha-D-glucosaminides82313DrugBank-show
NSC622171360199BindingDB-show
oxazine, 123648182BindingDB-show
oxazine, 1623634999BindingDB-show
oxazine, 1923635496BindingDB-show
oxazine, 9a23635748BindingDB-show
oxazine, 9c23634753BindingDB-show
oxazine, 9d23635749BindingDB-show
Parahydroxybenzaldehyde126BindingDB-show
Physostigmine salicylate657348BindingDB-show
PROPIDIUM4939BindingDB-show
pyrimidine, 26a23635257BindingDB-show
pyrimidine, 26b11656228BindingDB-show
Tacrine (THA) analogue 212051103BindingDB-show
tacrine derivative 15a11854653BindingDB-show
tacrine derivative 15b16094871BindingDB-show
tacrine derivative 15c16094854BindingDB-show
tacrine derivative 15d16094855BindingDB-show
tacrine derivative 15e16094872BindingDB-show
tacrine derivative 15f16094856BindingDB-show
tacrine derivative 15g16094873BindingDB-show
tacrine derivative 15h16094857BindingDB-show
tacrine derivative 15i16094874BindingDB-show
tacrine derivative 16a16094841BindingDB-show
tacrine derivative 16b16094875BindingDB-show
tacrine derivative 16c16094858BindingDB-show
tacrine derivative 16d16094859BindingDB-show
tacrine derivative 16e16094876BindingDB-show
tacrine derivative 16f16094860BindingDB-show
TACRINE(8)-4-AMINOQUINOLINE656986DrugBank-show
Tetraglycol8200DrugBank-show
Tetrahydroaminoacridine1935BindingDB-show
Trimethyl-[3-(2,2,2-trifluoroacetyl)phenyl]azanium5492BindingDB-show
Synonyms:
Acetylcholinesterase
AChE
Similar targets:
Uniprot name% Sequence similarity% Sequence identity
ACES_HUMAN68.452
ACES_RAT67.852.3
ACES_MOUSE67.852.7
CHLE_HUMAN65.948.1
Q9JKC1_RAT63.546
ACES_DROME51.134.3
O35535_RAT50.633.4
EST1_PIG50.134
ACES_CHICK49.639.2
EST2_HUMAN48.633.5
EST1_HUMAN47.932.1
EST1_RABIT47.831.4
O70177_RAT47.632.4
Q53H57_HUMAN46.932.4
CEL_BOVIN45.529.8
Q6IPK9_HUMAN44.830.5
Q4G0E9_HUMAN44.730.5
LIP1_CANRU42.128.7
Q6ED33_ASPNG41.625.8
LIP3_CANRU39.126.5
Q9JKS9_RAT31.116.4
ENTP1_BOVIN30.717.1
P71143_CLOTM30.618.2
ITK_HUMAN30.316.3
G6PI_RABIT30.216.9
FMO1_HUMAN30.117.9
SYYC_HUMAN30.118.8
Q9JKS8_RAT3017.1
Q86WD1_HUMAN3017.3
GLMS_ECOLI29.516.7
Protein-Protein Interactions:
No data available