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Target Details

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Name:Tyrosine-protein kinase ABL2
Uniprot name:ABL2_HUMAN
Accession Numbers:A0M8X0 P42684 Q5T0X6 Q5W0C5 Q6NZY6 Q7Z301
EC-Number:2.7.10.2
Organism:Homo sapiens
Human
PDB IDs:2ECD 2KK1 3GVU 3HMI
KEGG Pathways:show KEGG Pathways
Drugs:
NamePubChem IDSourceReferencesInteraction
3-((3R,4R)-4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperi9926791BindingDB-show
ABT-86911485656BindingDB-show
Adenosintriphosphorsaeure5957DrugBank-show
AMG 70611667893BindingDB-show
AST-48711409972BindingDB-show
Bosutinib5328940BindingDB-show
Canertinib156414BindingDB-show
CHEBI:1043465459219BindingDB-show
CHEBI:25992444329707BindingDB-show
CHEBI:66834345481533BindingDB-show
CHEBI:66834445481534BindingDB-show
CHEMBL124070352945601BindingDB-show
CHEMBL129007250908681BindingDB-show
CHEMBL21580316046126BindingDB-show
CHIR-26511656518BindingDB-show
CP-7247149874913BindingDB-show
Dasatinib3062316BindingDB-show
Dasatinib3062316DrugBank-show
Doramapimod156422BindingDB-show
Erlotinib176870BindingDB-show
Gefitinib123631BindingDB-show
GW-258011617559BindingDB-show
Imatinib Methansulfonate5291BindingDB-show
Lapatinib ditosylate208908BindingDB-show
Lestaurtinib126565BindingDB-show
MLN805411712649BindingDB-show
Pazopanib10113978BindingDB-show
Pelitinib6445562BindingDB-show
PI-1039884685BindingDB-show
PKC-4129829523BindingDB-show
Roscovitine160355BindingDB-show
Ruboxistaurin153999BindingDB-show
RWJ-3872525330790BindingDB-show
S1018_Selleck9977819BindingDB-show
S1147_Selleck16007391BindingDB-show
S1526_Selleck24889392BindingDB-show
SB 2021905353940BindingDB-show
SB-4315424521392BindingDB-show
SNS-0323025986BindingDB-show
sorafenibum216239BindingDB-show
STAUROSPORINE44259BindingDB-show
staurosporine44299148BindingDB-show
SU-1481310138259BindingDB-show
Sunitinib5329102BindingDB-show
Tandutinib3038522BindingDB-show
TbetaR-I Inhibitor447966BindingDB-show
Vandetanib3081361BindingDB-show
Vatalanib151194BindingDB-show
VX-6805494449BindingDB-show
VX-7453038525BindingDB-show
Synonyms:
Abelson murine leukemia viral oncogene homolog 2
Abelson-related gene protein
Tyrosine kinase ARG
Tyrosine-protein kinase ABL2
Similar targets:
Uniprot name% Sequence similarity% Sequence identity
Q59FK4_HUMAN60.450.7
ABL1_HUMAN59.850.3
ABL_MLVAB48.141.7
Q59F19_HUMAN45.436.4
ACK1_HUMAN30.520.3
DGKD_HUMAN29.717.4
HYSA_STRPN28.315.5
Q86UX3_HUMAN28.316.6
NOS3_MOUSE28.117.4
HDAC6_HUMAN2817.8
NOS3_HUMAN27.917.3
DPOL_HCMVA27.817.1
MRP5_HUMAN27.817
Q59FK6_HUMAN27.717
KCNQ5_HUMAN27.717.1
CA2D1_HUMAN27.715.9
Q6NYC5_HUMAN27.517
FAK1_HUMAN27.417.6
NOS3_RAT27.416.9
DPYD_HUMAN27.417.2
A3LQL4_PICST27.315.3
PYC_HUMAN27.216.5
SYIC_HUMAN26.915.9
Q26964_TRYCR26.616.7
SRC_RSVSE26.618.6
KCNQ3_HUMAN26.515.5
ACLY_RAT26.415.9
SRC_HUMAN26.418.8
ITA1_HUMAN26.416.3
SRC_RAT26.318.5
Protein-Protein Interactions: