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Target Details

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Name:5'-AMP-activated protein kinase catalytic subunit alpha-1
Uniprot name:AAPK1_HUMAN
Accession Numbers:A8MTQ6 B2R7E1 O00286 Q13131 Q5D0E1 Q86VS1 Q9UNQ4
EC-Number:2.7.11.1
Organism:Homo sapiens
Human
PDB IDs:-
KEGG Pathways:show KEGG Pathways
Drugs:
NamePubChem IDSourceReferencesInteraction
3-((3R,4R)-4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperi9926791BindingDB-show
ABT-86911485656BindingDB-show
Adenosintriphosphorsaeure5957DrugBank-show
AMG 70611667893BindingDB-show
AST-48711409972BindingDB-show
Canertinib156414BindingDB-show
CHEBI:1043465459219BindingDB-show
CHEBI:25992444329707BindingDB-show
CHEBI:66834345481533BindingDB-show
CHEBI:66834445481534BindingDB-show
CHEMBL124070352945601BindingDB-show
CHIR-26511656518BindingDB-show
CP-7247149874913BindingDB-show
Dasatinib3062316BindingDB-show
Doramapimod156422BindingDB-show
Erlotinib176870BindingDB-show
Gefitinib123631BindingDB-show
GW-258011617559BindingDB-show
hesperadin10142586BindingDB-show
Imatinib Methansulfonate5291BindingDB-show
Lapatinib ditosylate208908BindingDB-show
Lestaurtinib126565BindingDB-show
MLN805411712649BindingDB-show
Muskeladenylsaeure6083DrugBank-show
Pazopanib10113978BindingDB-show
Phenylethylbiguanide8249DrugBank-show
PI-1039884685BindingDB-show
PKC-4129829523BindingDB-show
Roscovitine160355BindingDB-show
Ruboxistaurin153999BindingDB-show
RWJ-3872525330790BindingDB-show
S1018_Selleck9977819BindingDB-show
S1147_Selleck16007391BindingDB-show
S1526_Selleck24889392BindingDB-show
SB 2021905353940BindingDB-show
SB-4315424521392BindingDB-show
SNS-0323025986BindingDB-show
sorafenibum216239BindingDB-show
STAUROSPORINE44259BindingDB-show
staurosporine44299148BindingDB-show
SU-1481310138259BindingDB-show
Sunitinib5329102BindingDB-show
Tandutinib3038522BindingDB-show
Vandetanib3081361BindingDB-show
Vatalanib151194BindingDB-show
VX-6805494449BindingDB-show
VX-7453038525BindingDB-show
Synonyms:
5'-AMP-activated protein kinase catalytic subunit alpha-1
AMPK alpha-1 chain
Similar targets:
Uniprot name% Sequence similarity% Sequence identity
AAPK2_HUMAN84.474.7
CHK1_SCHPO41.824.6
CHK1_YEAST4024.4
KCC2A_RAT33.121.2
RADI_MOUSE32.717.6
Q8L103_HELPY31.816.5
PLK1_HUMAN31.719.7
DPO3X_ECOLI31.417.5
PYRG2_HUMAN30.718.2
KS6B1_BOVIN30.718.5
6PGD_SHEEP30.617.3
VATA_HUMAN30.617.6
TBA1C_HUMAN30.417.5
CP26B_HUMAN30.416.7
KS6B1_HUMAN30.418.4
O25319_HELPY30.216.7
SYYC_HUMAN30.215.8
PAOX_ARTGO30.117.2
Q8CHM5_MOUSE30.117.7
THAS_HUMAN30.117.3
GALT1_MOUSE3017.4
IKKA_HUMAN3018.7
12S_PROFR29.916.2
SYK_HUMAN29.918
Q53GX4_HUMAN29.917.6
CKI1_SCHPO29.916.9
GBRA4_HUMAN29.917.3
VATA_PLAF729.814.9
Q9H4D1_HUMAN29.816.2
KMO_RAT29.716.5
Protein-Protein Interactions: