Home
Drugs
Targets
Pathways
Ontologies
Cyp450s
Adv.search
Help/FAQ

Target Details

add
Name:Amyloid beta A4 protein
Uniprot name:A4_HUMAN
Accession Numbers:B2R5V1 P05067 P09000 P78438 Q13764 Q13778 Q13793 Q16011 Q16014 Q16019 Q16020 Q6GSC0 Q8WZ99 Q9BT38 Q9UC33 Q9UCA9 Q9UCB6 Q9UCC8 Q9UCD1 Q9UQ58
EC-Number:-
Organism:Homo sapiens
Human
PDB IDs:1AAP 1AMB 1AMC 1AML 1BA4 1BA6 1BJB 1BJC 1BRC 1CA0 1HZ3 1IYT 1MWP 1OWT 1QCM 1QWP 1QXC 1QYT 1RW6 1TAW 1TKN 1UO7 1UO8 1UOA 1UOI 1X11 1Z0Q 1ZE7 1ZE9 1ZJD 2BEG 2BOM 2BP4 2FJZ 2FK1 2FK2 2FK3 2FKL 2FMA 2G47 2IPU 2OTK 2R0W 3DXC 3DXD 3DXE 3GCI
KEGG Pathways:show KEGG Pathways
Drugs:
NamePubChem IDSourceReferencesInteraction
2,5-bis(4-methoxyphenyl)thiophene3552928BindingDB-show
2,5-bis(4-nitrophenyl)thiophene4373578BindingDB-show
2-(4-Bromophenyl)-6-methylimidazo[1,2-a]pyridine837893BindingDB-show
2-(4-dimethylaminophenyl)-6-iodo-chromen-4-one11574659BindingDB-show
2-(4-hydroxyphenyl)-6-iodo-chromen-4-one11703303BindingDB-show
2-(4-methylaminophenyl)benzofuran-5-ol11550464BindingDB-show
2-(fluoromethyl)-3-[4-[(E)-2-(4-methylaminophenyl)ethenyl]phenoxy]propan-111674077BindingDB-show
2-[[4-[(E)-2-(4-dimethylaminophenyl)ethenyl]phenoxy]methyl]-3-fluoro-propa11638480BindingDB-show
4-(1,3-Benzothiazol-2-yl)-N,N-dimethylaniline95755BindingDB-show
4-(6-iodobenzothiazol-2-yl)-N,N-dimethyl-aniline10547782BindingDB-show
4-(6-methoxybenzothiazol-2-yl)-N,N-dimethyl-aniline11129817BindingDB-show
4-Amino-4'-hydroxystilbene5375988BindingDB-show
4-Benzothiazol-2-ylphenylamine234475BindingDB-show
6-iodo-2-(4-methylaminophenyl)chromen-4-one11632242BindingDB-show
6-iodo-2-[4-(4-methylpiperazin-1-yl)phenyl]benzothiazole10844298BindingDB-show
AC1O1Q5Y6177872BindingDB-show
AIDS045959466289BindingDB-show
an-5-ol11543378BindingDB-show
BTA-19837643BindingDB-show
CHEMBL108913711719190BindingDB-show
CHEMBL108918611684817BindingDB-show
CHEMBL109054211642048BindingDB-show
CHEMBL109054346884664BindingDB-show
CHEMBL109121911576068BindingDB-show
CHEMBL109134311532527BindingDB-show
CHEMBL109199911561538BindingDB-show
CHEMBL109200011705141BindingDB-show
CHEMBL109222711596660BindingDB-show
CHEMBL109287911573395BindingDB-show
CHEMBL109291346884581BindingDB-show
CHEMBL109315211574638BindingDB-show
CHEMBL109345011619220BindingDB-show
CHEMBL109380611546946BindingDB-show
CHEMBL109380711504350BindingDB-show
CHEMBL18064125263467BindingDB-show
CHEMBL18276844391426BindingDB-show
CHEMBL18380544391470BindingDB-show
CHEMBL18380644391471BindingDB-show
CHEMBL18381544391488BindingDB-show
CHEMBL19390011565846BindingDB-show
CHEMBL1939719972775BindingDB-show
CHEMBL19402011530779BindingDB-show
CHEMBL19427411673829BindingDB-show
CHEMBL19469211645550BindingDB-show
CHEMBL19597011565868BindingDB-show
CHEMBL19607011566215BindingDB-show
CHEMBL19621344403923BindingDB-show
CHEMBL19624610471478BindingDB-show
CHEMBL19627911580454BindingDB-show
CHEMBL19632111644770BindingDB-show
CHEMBL19632211529378BindingDB-show
CHEMBL19638711626862BindingDB-show
CHEMBL19640711544421BindingDB-show
CHEMBL19694111638208BindingDB-show
CHEMBL1969459996409BindingDB-show
CHEMBL19694611709395BindingDB-show
CHEMBL19694711609939BindingDB-show
CHEMBL19714011582291BindingDB-show
CHEMBL19720211602469BindingDB-show
CHEMBL19859711507713BindingDB-show
CHEMBL19859821299300BindingDB-show
CHEMBL20293844408848BindingDB-show
CHEMBL20332044408839BindingDB-show
CHEMBL20401014905189BindingDB-show
CHEMBL20487344408693BindingDB-show
CHEMBL20533211500527BindingDB-show
CHEMBL20540310425576BindingDB-show
CHEMBL20551244408965BindingDB-show
CHEMBL20582444408840BindingDB-show
CHEMBL20622411623805BindingDB-show
CHEMBL20742344411898BindingDB-show
CHEMBL20764924858429BindingDB-show
CHEMBL20845611507217BindingDB-show
CHEMBL20845711608986BindingDB-show
CHEMBL21511016087293BindingDB-show
CHEMBL21643216087304BindingDB-show
CHEMBL21655310064445BindingDB-show
CHEMBL21686416087292BindingDB-show
CHEMBL21792316087305BindingDB-show
CHEMBL23093144425707BindingDB-show
CHEMBL23103544425709BindingDB-show
CHEMBL23112544425696BindingDB-show
CHEMBL23124844425716BindingDB-show
CHEMBL23125010143259BindingDB-show
CHEMBL23135144425720BindingDB-show
CHEMBL23144644425691BindingDB-show
CHEMBL23144744425692BindingDB-show
CHEMBL23144844425722BindingDB-show
CHEMBL23144944425723BindingDB-show
CHEMBL23154444425694BindingDB-show
CHEMBL23154544425710BindingDB-show
CHEMBL23154744425724BindingDB-show
CHEMBL23154844425725BindingDB-show
CHEMBL23164744425712BindingDB-show
CHEMBL23618244435381BindingDB-show
CHEMBL23618344435383BindingDB-show
CHEMBL23618424180452BindingDB-show
CHEMBL23618544435385BindingDB-show
CHEMBL23618644435386BindingDB-show
CHEMBL23618744435387BindingDB-show
CHEMBL23618844435388BindingDB-show
CHEMBL23618944435389BindingDB-show
CHEMBL23619044435390BindingDB-show
CHEMBL23619144435391BindingDB-show
CHEMBL23619244435393BindingDB-show
CHEMBL23619644435395BindingDB-show
CHEMBL23827144435379BindingDB-show
CHEMBL23962911851431BindingDB-show
CHEMBL23985844435363BindingDB-show
CHEMBL23985944435364BindingDB-show
CHEMBL24005511354073BindingDB-show
CHEMBL24006944435366BindingDB-show
CHEMBL24007044435367BindingDB-show
CHEMBL24007144435368BindingDB-show
CHEMBL24028444435369BindingDB-show
CHEMBL24028544435371BindingDB-show
CHEMBL24028644435372BindingDB-show
CHEMBL26400610042056BindingDB-show
CHEMBL29178415054176BindingDB-show
CHEMBL30563415521136BindingDB-show
CHEMBL30992010947017BindingDB-show
CHEMBL31024244313401BindingDB-show
CHEMBL31044410983792BindingDB-show
CHEMBL31103511089783BindingDB-show
CHEMBL31262222380809BindingDB-show
CHEMBL32866010426074BindingDB-show
CHEMBL36034144391494BindingDB-show
CHEMBL36047311351105BindingDB-show
CHEMBL36074044391570BindingDB-show
CHEMBL37106611660650BindingDB-show
CHEMBL37275111516139BindingDB-show
CHEMBL3728469976141BindingDB-show
CHEMBL37727944408847BindingDB-show
CHEMBL37792911537013BindingDB-show
CHEMBL37936310637399BindingDB-show
CHEMBL38047611499570BindingDB-show
CHEMBL38077811573705BindingDB-show
CHEMBL38164210013901BindingDB-show
CHEMBL38170844411893BindingDB-show
CHEMBL38173111587026BindingDB-show
CHEMBL38199144408738BindingDB-show
CHEMBL38200721788024BindingDB-show
CHEMBL38240744411897BindingDB-show
CHEMBL38272111508700BindingDB-show
CHEMBL38446516087306BindingDB-show
CHEMBL38673716087291BindingDB-show
CHEMBL38727616087303BindingDB-show
CHEMBL38954944425693BindingDB-show
CHEMBL39047844425695BindingDB-show
CHEMBL39088944425713BindingDB-show
CHEMBL39205944435382BindingDB-show
CHEMBL39206044435384BindingDB-show
CHEMBL39214444435378BindingDB-show
CHEMBL39394144435394BindingDB-show
CHEMBL39413244435380BindingDB-show
CHEMBL39531244425715BindingDB-show
CHEMBL39531344425718BindingDB-show
CHEMBL39654244425721BindingDB-show
CHEMBL39654310311969BindingDB-show
CHEMBL39839544435370BindingDB-show
CHEMBL40042044435362BindingDB-show
CHEMBL42486344408778BindingDB-show
CHEMBL42530444425697BindingDB-show
CHEMBL42754811523521BindingDB-show
CHEMBL42944844435392BindingDB-show
CHEMBL42944911785317BindingDB-show
CHEMBL43648310364928BindingDB-show
CHEMBL43897244408841BindingDB-show
CHEMBL44280144435365BindingDB-show
CHEMBL44309744548169BindingDB-show
CHEMBL44439344548347BindingDB-show
CHEMBL44687044548162BindingDB-show
CHEMBL45055325149265BindingDB-show
CHEMBL45092644313381BindingDB-show
CHEMBL48979244548515BindingDB-show
CHEMBL48997844548163BindingDB-show
CHEMBL48997944548006BindingDB-show
CHEMBL48999444548514BindingDB-show
CHEMBL49079844548167BindingDB-show
CHEMBL49079944548344BindingDB-show
CHEMBL49080644548351BindingDB-show
CHEMBL49080844548349BindingDB-show
CHEMBL49120344548165BindingDB-show
CHEMBL49140644548166BindingDB-show
CHEMBL49140744548168BindingDB-show
CHEMBL49202344548345BindingDB-show
CHEMBL49202444548346BindingDB-show
CHEMBL49221644548342BindingDB-show
CHEMBL49221744548343BindingDB-show
CHEMBL50908844548007BindingDB-show
CHEMBL52192944548516BindingDB-show
CHEMBL52382425110763BindingDB-show
CHEMBL52411444548164BindingDB-show
CHEMBL52414125110762BindingDB-show
CHEMBL5540110496851BindingDB-show
CHEMBL5553610762840BindingDB-show
CHEMBL58204411543843BindingDB-show
CHEMBL58916346225190BindingDB-show
CHEMBL59083016051586BindingDB-show
CHEMBL59996516050931BindingDB-show
CHEMBL7434815521137BindingDB-show
CHEMBL7487444313421BindingDB-show
CHEMBL7518344313410BindingDB-show
CHEMBL7611215521135BindingDB-show
CHEMBL7801210133297BindingDB-show
CHEMBL7841011139152BindingDB-show
CHEMBL7862111054105BindingDB-show
CHEMBL812609839907BindingDB-show
CHEMBL8168510889525BindingDB-show
CHEMBL9144910956585BindingDB-show
CHEMBL9280110978824BindingDB-show
CHEMBL9280211821524BindingDB-show
CHEMBL9285210335228BindingDB-show
CHEMBL9312410171487BindingDB-show
CHEMBL9327010922978BindingDB-show
CHEMBL9388410444413BindingDB-show
CHEMBL942309835167BindingDB-show
Chrysamine G6913223BindingDB-show
CID 1037041210745352BindingDB-show
CID 1048197710815986BindingDB-show
CID 1122543810184360BindingDB-show
CID 984776011488357BindingDB-show
CID 98492119849211BindingDB-show
CID 984921111455014BindingDB-show
Congo red11313BindingDB-show
DHPT7087BindingDB-show
Diferaloylmethane969516BindingDB-show
FLURBIPROFEN3394BindingDB-show
Gosogliptin (USAN/INN)11516136BindingDB-show
Iodochlorohydroxyquinoline2788SuperTargetPMID 12198135show
lamine11579589BindingDB-show
N-methyl-4-(6-methylbenzothiazol-2-yl)aniline10422457BindingDB-show
nchembio.65-comp716954BindingDB-show
NSC691533391870BindingDB-show
Orthohydroxybenzoic acid338BindingDB-show
ST0781033743359BindingDB-show
Tarenflurbil92337BindingDB-show
Thioflavine T16953BindingDB-show
Vanillylidenacetone5354238BindingDB-show
yl]-dimethyl-amine11673398BindingDB-show
yl]-methyl-amine11708629BindingDB-show
ZINC0005693682450BindingDB-show
Synonyms:
ABPP
Alzheimer disease amyloid protein
Amyloid beta A4 protein
APP
APPI
Cerebral vascular amyloid peptide
CVAP
PN-II
PreA4
Protease nexin-II
Similar targets:
Uniprot name% Sequence similarity% Sequence identity
Q29517_RABIT31.617.4
DPO1_ECOLI30.416.4
ZFY_HUMAN30.217.8
LDLR_MOUSE3018.5
Q53688_9CREN3015.4
Q9RIK9_THEMA3017.4
PBPC_BACSU29.716.8
RAD50_PYRFU29.516
Q8MPM3_LEIME29.316.8
EFG_THETH29.318.7
PLOD1_HUMAN29.317.7
C1S_HUMAN2917
PLCD1_RAT28.915.8
F13A_HUMAN28.815.6
ECE1_RAT28.816.1
RIPK1_HUMAN28.616
SECA1_MYCTU28.516.6
NANH_VIBCH28.516.5
GOX_ASPNG28.416.3
GCYA3_HUMAN28.216.4
PARC_HAEIN28.115.8
CHEA_THEMA28.114.2
B5RQL7_BORRA28.115.3
LDLR_HUMAN2816.9
TGM5_HUMAN2816.5
MALQ_THELI27.917
PCCA_HUMAN27.915.8
PLCL1_HUMAN27.716
ASPH_HUMAN27.716
PBP2_STRPN27.715.1
Protein-Protein Interactions:
Uniprot nameSource
ULA1_HUMANPMID 16189514,8626687
UCHL1_HUMAN2 PMIDs
TTHY_HUMAN3 PMIDs
TRY3_HUMAN4 PMIDs
TRY2_HUMAN5 PMIDs
TRY1_HUMAN6 PMIDs
TNR21_HUMAN7 PMIDs
TM2D1_HUMAN8 PMIDs
TAU_HUMAN9 PMIDs
TAU_HUMAN10 PMIDs
SYUB_HUMAN11 PMIDs
SYUA_HUMAN12 PMIDs
SPTA2_HUMAN13 PMIDs
SPON1_HUMAN14 PMIDs
SHC3_HUMAN15 PMIDs
SHC1_HUMAN16 PMIDs
Q7Z5F4_HUMAN17 PMIDs
PRIO_HUMAN18 PMIDs
PREP_HUMAN19 PMIDs
PPID_HUMAN20 PMIDs
PIN1_HUMAN21 PMIDs
PGS1_HUMAN22 PMIDs
PDIA3_HUMAN23 PMIDs
PDIA3_HUMAN24 PMIDs
NUMB_HUMAN25 PMIDs
NUMBL_HUMAN26 PMIDs
NID1_HUMAN27 PMIDs
NFL_HUMAN28 PMIDs
NF1_HUMAN29 PMIDs
NECA3_HUMAN30 PMIDs
NECA3_HUMAN31 PMIDs
MYH9_HUMAN32 PMIDs
MBP_HUMAN33 PMIDs
M3K5_HUMAN34 PMIDs
LRP1_HUMAN35 PMIDs
LRP1B_HUMAN36 PMIDs
LAMA1_HUMAN37 PMIDs
KNG1_HUMAN38 PMIDs
KLK6_HUMAN39 PMIDs
KLC1_HUMAN40 PMIDs
KLC1_HUMAN41 PMIDs
JIP2_HUMAN42 PMIDs
JIP1_HUMAN43 PMIDs
JIP1_HUMAN44 PMIDs
ITM2B_HUMAN45 PMIDs
ITM2A_HUMAN46 PMIDs
IDE_HUMAN47 PMIDs
HUNIN_HUMAN48 PMIDs
HTRA2_HUMAN49 PMIDs
HSP7C_HUMAN50 PMIDs
HOME3_HUMAN51 PMIDs
HOME2_HUMAN52 PMIDs
HMOX2_HUMAN53 PMIDs
HGS_HUMAN54 PMIDs
HCD2_HUMAN55 PMIDs
GSK3B_HUMAN56 PMIDs
GSK3A_HUMAN57 PMIDs
GPC1_HUMAN58 PMIDs
GFAP_HUMAN59 PMIDs
GELS_HUMAN60 PMIDs
FLOT1_HUMAN61 PMIDs
FBLN1_HUMAN62 PMIDs
FA12_HUMAN63 PMIDs
DYN1_HUMAN64 PMIDs
DYH1_HUMAN65 PMIDs
DAB2_HUMAN66 PMIDs
DAB1_HUMAN67 PMIDs
CTRB1_HUMAN68 PMIDs
CSTN1_HUMAN69 PMIDs
CRYAB_HUMAN70 PMIDs
CRYAB_HUMAN71 PMIDs
CRYAB_HUMAN72 PMIDs
COPA1_HUMAN73 PMIDs
CO4A6_HUMAN74 PMIDs
CO4A5_HUMAN75 PMIDs
CO4A3_HUMAN76 PMIDs
CO4A2_HUMAN77 PMIDs
CO4A1_HUMAN78 PMIDs
CNTN4_HUMAN79 PMIDs
CNTN3_HUMAN80 PMIDs
CLUS_HUMAN81 PMIDs
CDK5_HUMAN82 PMIDs
CATD_HUMAN83 PMIDs
CATA_HUMAN84 PMIDs
CASP6_HUMAN85 PMIDs
CASP4_HUMAN86 PMIDs
CALR_HUMAN87 PMIDs
CALR_HUMAN88 PMIDs
BLMH_HUMAN89 PMIDs
BAP31_HUMAN90 PMIDs
BACE2_HUMAN91 PMIDs
BACE1_HUMAN92 PMIDs
ASPP2_HUMAN93 PMIDs
APLP2_HUMAN94 PMIDs
APLP1_HUMAN95 PMIDs
APBP2_HUMAN96 PMIDs
APBB3_HUMAN97 PMIDs
APBB2_HUMAN98 PMIDs
APBB1_HUMAN99 PMIDs
APBB1_HUMAN100 PMIDs
APBA3_HUMAN101 PMIDs
APBA2_HUMAN102 PMIDs
APBA2_HUMAN103 PMIDs
APBA1_HUMAN104 PMIDs
ADA17_HUMAN105 PMIDs
ACTB_HUMAN106 PMIDs
ACHA7_HUMAN107 PMIDs
ACES_HUMAN108 PMIDs
ABL1_HUMAN109 PMIDs
AACT_HUMAN110 PMIDs
A4_HUMAN111 PMIDs
41_HUMAN112 PMIDs
1433Z_HUMAN113 PMIDs
1433Z_HUMAN114 PMIDs