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Target Details

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Name:5-HT-4
Uniprot name:5HT4R_HUMAN
Accession Numbers:Q13639 Q96KH9 Q96KI0 Q9H199 Q9NY73 Q9UBM6 Q9UBT4 Q9UE22 Q9UE23 Q9UQR6
EC-Number:-
Organism:Homo sapiens
Human
PDB IDs:-
KEGG Pathways:show KEGG Pathways
Drugs:
NamePubChem IDSourceReferencesInteraction
(1-(2-(Methylsulfonylamino)ethyl)-4-piperidinyl)methyl 1-methyl-1H-indole-3-carboxylate119376BindingDB-show
1-(2-aminopropyl)-2H-indazol-6-one9834183BindingDB-show
2-(2-methyl-1-piperidyl)ethyl 4-amino-5-chloro-2-methoxy-benzoate10449091BindingDB-show
2-(Diethylamino)ethyl 4-amino-5-chloro-2-methoxybenzoate5191BindingDB-show
4-amino-5-chloro-2-methoxy-N-(1-methylpiperidin-4-yl)benzamide44573BindingDB-show
4-Amino-5-chloro-N-(2-piperidinoethyl)-o-anisamide203435BindingDB-show
4437585444375854BindingDB-show
740873-06-711430856BindingDB-show
AC1L2YB7130946BindingDB-show
AC1L2ZOK131725BindingDB-show
AC1MHYZY3035241BindingDB-show
AC1MI81F3019427BindingDB-show
Almotriptan123606SuperTarget-show
BARETTIN11177588BindingDB-show
Brl-246829797313BindingDB-show
BRN 3656100197237BindingDB-show
CHEBI:14978344329468BindingDB-show
CHEBI:37206917698BindingDB-show
CHEMBL10008810594888BindingDB-show
CHEMBL10019910546395BindingDB-show
CHEMBL10031310522484BindingDB-show
CHEMBL10031710832327BindingDB-show
CHEMBL10347910020895BindingDB-show
CHEMBL108378744240743BindingDB-show
CHEMBL12005510385855BindingDB-show
CHEMBL12176610812045BindingDB-show
CHEMBL12177610524522BindingDB-show
CHEMBL1219139800656BindingDB-show
CHEMBL12208344348466BindingDB-show
CHEMBL12281810834000BindingDB-show
CHEMBL12291410715463BindingDB-show
CHEMBL12297310836823BindingDB-show
CHEMBL12337710408029BindingDB-show
CHEMBL12448510717193BindingDB-show
CHEMBL12500510781509BindingDB-show
CHEMBL125560649780155BindingDB-show
CHEMBL12567010550242BindingDB-show
CHEMBL12571610526438BindingDB-show
CHEMBL125799152945318BindingDB-show
CHEMBL125810849783206BindingDB-show
CHEMBL125810949783207BindingDB-show
CHEMBL125822249783208BindingDB-show
CHEMBL125822349783209BindingDB-show
CHEMBL125833849783210BindingDB-show
CHEMBL125833949783211BindingDB-show
CHEMBL125845049783212BindingDB-show
CHEMBL125845149783414BindingDB-show
CHEMBL125845249783415BindingDB-show
CHEMBL125855949783416BindingDB-show
CHEMBL125856049783417BindingDB-show
CHEMBL125856149783418BindingDB-show
CHEMBL125867149783419BindingDB-show
CHEMBL125867249783420BindingDB-show
CHEMBL125878649783421BindingDB-show
CHEMBL12592611794824BindingDB-show
CHEMBL12609810716689BindingDB-show
CHEMBL127570949836386BindingDB-show
CHEMBL127579149836496BindingDB-show
CHEMBL12787610645984BindingDB-show
CHEMBL15563110548275BindingDB-show
CHEMBL15568210854687BindingDB-show
CHEMBL1559179905972BindingDB-show
CHEMBL15608810764565BindingDB-show
CHEMBL15618811727962BindingDB-show
CHEMBL15620611050452BindingDB-show
CHEMBL15634810690483BindingDB-show
CHEMBL15634910381762BindingDB-show
CHEMBL15649910544078BindingDB-show
CHEMBL15655410570203BindingDB-show
CHEMBL15657910757373BindingDB-show
CHEMBL15696544371317BindingDB-show
CHEMBL15697010447437BindingDB-show
CHEMBL15763110018558BindingDB-show
CHEMBL15788015295138BindingDB-show
CHEMBL15814710498232BindingDB-show
CHEMBL1582389973684BindingDB-show
CHEMBL16023710788092BindingDB-show
CHEMBL16058110048222BindingDB-show
CHEMBL16070510802184BindingDB-show
CHEMBL16351910476255BindingDB-show
CHEMBL16491944379041BindingDB-show
CHEMBL17207444384689BindingDB-show
CHEMBL17231444384672BindingDB-show
CHEMBL17280244384728BindingDB-show
CHEMBL17289944384684BindingDB-show
CHEMBL17308944384735BindingDB-show
CHEMBL17428444384896BindingDB-show
CHEMBL17452444384738BindingDB-show
CHEMBL17493544214754BindingDB-show
CHEMBL17667244385532BindingDB-show
CHEMBL17757344385634BindingDB-show
CHEMBL18958011600413BindingDB-show
CHEMBL19663311686414BindingDB-show
CHEMBL19774544404965BindingDB-show
CHEMBL19775111650641BindingDB-show
CHEMBL19775244404960BindingDB-show
CHEMBL19796511577105BindingDB-show
CHEMBL19805211593090BindingDB-show
CHEMBL19822644404969BindingDB-show
CHEMBL19827111629268BindingDB-show
CHEMBL19828144404957BindingDB-show
CHEMBL19837111520559BindingDB-show
CHEMBL19837211686510BindingDB-show
CHEMBL19850444404968BindingDB-show
CHEMBL19861044404959BindingDB-show
CHEMBL19866811629247BindingDB-show
CHEMBL19871944404958BindingDB-show
CHEMBL19892144404964BindingDB-show
CHEMBL19915044404962BindingDB-show
CHEMBL2074812861897BindingDB-show
CHEMBL23012344427808BindingDB-show
CHEMBL24126744427796BindingDB-show
CHEMBL24434544427805BindingDB-show
CHEMBL26912544427810BindingDB-show
CHEMBL28819910828800BindingDB-show
CHEMBL29386610335971BindingDB-show
CHEMBL29489444299805BindingDB-show
CHEMBL29884244299936BindingDB-show
CHEMBL29940810522209BindingDB-show
CHEMBL31294011146446BindingDB-show
CHEMBL31552610930618BindingDB-show
CHEMBL31559011146533BindingDB-show
CHEMBL31714610760942BindingDB-show
CHEMBL31727710835243BindingDB-show
CHEMBL31737710615428BindingDB-show
CHEMBL31806810498685BindingDB-show
CHEMBL31876411791805BindingDB-show
CHEMBL31988610643950BindingDB-show
CHEMBL32197010833313BindingDB-show
CHEMBL32549410521792BindingDB-show
CHEMBL32799911093246BindingDB-show
CHEMBL32864110742816BindingDB-show
CHEMBL32891811813852BindingDB-show
CHEMBL3298644281491BindingDB-show
CHEMBL33084810741078BindingDB-show
CHEMBL33126410623729BindingDB-show
CHEMBL33139610548505BindingDB-show
CHEMBL33255310644148BindingDB-show
CHEMBL33302810669143BindingDB-show
CHEMBL33432511796362BindingDB-show
CHEMBL3367614403199BindingDB-show
CHEMBL3373244281102BindingDB-show
CHEMBL33813610830094BindingDB-show
CHEMBL33993610669778BindingDB-show
CHEMBL33998044352308BindingDB-show
CHEMBL3422444281492BindingDB-show
CHEMBL3426310270343BindingDB-show
CHEMBL3472359905514BindingDB-show
CHEMBL3483119973683BindingDB-show
CHEMBL35157044371350BindingDB-show
CHEMBL3519510292429BindingDB-show
CHEMBL3519610291662BindingDB-show
CHEMBL352269881053BindingDB-show
CHEMBL358089819953BindingDB-show
CHEMBL359729857899BindingDB-show
CHEMBL361209858485BindingDB-show
CHEMBL365589881054BindingDB-show
CHEMBL36698644384630BindingDB-show
CHEMBL36787744385584BindingDB-show
CHEMBL36821344384721BindingDB-show
CHEMBL36884444384769BindingDB-show
CHEMBL3690379911674BindingDB-show
CHEMBL37018111520655BindingDB-show
CHEMBL37018211686484BindingDB-show
CHEMBL37022744404961BindingDB-show
CHEMBL37064644404966BindingDB-show
CHEMBL37079644404955BindingDB-show
CHEMBL37085844404970BindingDB-show
CHEMBL37128044404956BindingDB-show
CHEMBL37170711527897BindingDB-show
CHEMBL37171811714901BindingDB-show
CHEMBL37247911693471BindingDB-show
CHEMBL38254311629240BindingDB-show
CHEMBL38294144404963BindingDB-show
CHEMBL38981744427802BindingDB-show
CHEMBL39000944427804BindingDB-show
CHEMBL39007511622025BindingDB-show
CHEMBL39020244427806BindingDB-show
CHEMBL39020344427807BindingDB-show
CHEMBL39020444427809BindingDB-show
CHEMBL39020511513350BindingDB-show
CHEMBL39746344427794BindingDB-show
CHEMBL39746544427803BindingDB-show
CHEMBL39920311304851BindingDB-show
CHEMBL40837911643822BindingDB-show
CHEMBL4090321852725BindingDB-show
CHEMBL4162669934117BindingDB-show
CHEMBL4176910757374BindingDB-show
CHEMBL41770610381927BindingDB-show
CHEMBL41878610669163BindingDB-show
CHEMBL41879010762293BindingDB-show
CHEMBL42016610811181BindingDB-show
CHEMBL42118710552840BindingDB-show
CHEMBL42125610645103BindingDB-show
CHEMBL42532944384624BindingDB-show
CHEMBL42621644386218BindingDB-show
CHEMBL43314910897011BindingDB-show
CHEMBL43398444386168BindingDB-show
CHEMBL48142510046170BindingDB-show
CHEMBL4837910567201BindingDB-show
CHEMBL4869810568248BindingDB-show
CHEMBL4907210615288BindingDB-show
CHEMBL4926610569278BindingDB-show
CHEMBL49367716005860BindingDB-show
CHEMBL5085210545215BindingDB-show
CHEMBL51160944559159BindingDB-show
CHEMBL51868244559101BindingDB-show
CHEMBL56935745485614BindingDB-show
CHEMBL56958545485620BindingDB-show
CHEMBL5699444300153BindingDB-show
CHEMBL57048745485653BindingDB-show
CHEMBL57071045485604BindingDB-show
CHEMBL57179944626295BindingDB-show
CHEMBL57203845485563BindingDB-show
CHEMBL57224845485619BindingDB-show
CHEMBL57224945485564BindingDB-show
CHEMBL5768644300154BindingDB-show
CHEMBL58368145485675BindingDB-show
CHEMBL58474345485562BindingDB-show
CHEMBL58556744626294BindingDB-show
CHEMBL58592545485624BindingDB-show
CHEMBL8512510347130BindingDB-show
CHEMBL8662410919426BindingDB-show
CHEMBL8677711039730BindingDB-show
CHEMBL8698511039391BindingDB-show
CHEMBL8706311813759BindingDB-show
CHEMBL8835511135810BindingDB-show
CHEMBL8922511005668BindingDB-show
CHEMBL9055911966400BindingDB-show
CHEMBL9361110667079BindingDB-show
CHEMBL9523510761898BindingDB-show
CHEMBL9566111726706BindingDB-show
CHEMBL9568510833513BindingDB-show
CHEMBL9580810761897BindingDB-show
CHEMBL9596810530232BindingDB-show
CHEMBL9696010616510BindingDB-show
CHEMBL9701910666935BindingDB-show
CHEMBL9750810831381BindingDB-show
CHEMBL9775510045643BindingDB-show
CHEMBL9790311799161BindingDB-show
CHEMBL9909610739345BindingDB-show
CHEMBL9914110741712BindingDB-show
CHEMBL9914710737191BindingDB-show
CHEMBL9929910744355BindingDB-show
CHEMBL9938310545330BindingDB-show
CHEMBL9945210687803BindingDB-show
CHEMBL9951510664258BindingDB-show
CHEMBL9957710590554BindingDB-show
CHEMBL9957810543526BindingDB-show
CHEMBL9959010688750BindingDB-show
CHEMBL9959110688893BindingDB-show
CHEMBL9972310666045BindingDB-show
CID 98560419856041BindingDB-show
CID1006954510069545BindingDB-show
Clebopride2780BindingDB-show
Cyproheptadine2913SuperTarget-show
Cyproheptadine13770SuperTarget-show
Domperidone Monohydrochloride3151BindingDB-show
Enteropride2769BindingDB-show
Enteropride2769DrugBank-show
Enteropride2769SuperTarget2 PMIDsshow
Granisetron5284566BindingDB-show
Granisetron Monohydrochloride3510BindingDB-show
Granisetron Monohydrochloride3510SuperTarget-show
iodozacopride108182BindingDB-show
Lerisetron65997BindingDB-show
M7319_SIGMA5311299BindingDB-show
Methochlopramide4168BindingDB-show
Methochlopramide4168SuperTarget2 PMIDsshow
Mosapride119584BindingDB-show
N-[9-(1-methyl-4-piperidyl)-2,7-diazabicyclo[4.3.0]nona-2,4,8,10-tetraen-39947817BindingDB-show
PDSP1_00138910331436BindingDB-show
PDSP2_001604132337BindingDB-show
PDSP2_0016839819593BindingDB-show
Prucalopride3052762BindingDB-show
Risatriptan5078DrugBank-show
SB2077105311423BindingDB-show
SPBio_0011805362436BindingDB-show
Sumatriptanum5358SuperTarget-show
Tegaserod5487301DrugBank-show
Tegaserod5487301SuperTargetPMID 015324710show
Thrombocytin5202BindingDB-show
Tocris-0728182593BindingDB-show
Tocris-17956604914BindingDB-show
Tropisetron656665BindingDB-show
Tropisetron72165SuperTarget2 PMIDsshow
Tropisetron656665SuperTarget2 PMIDsshow
ZINC013831491471834BindingDB-show
Zolmitriptan441240DrugBank-show
zolmitriptan5731DrugBank-show
Zolmitriptan60857DrugBank-show
Synonyms:
5-HT-4
5-HT4
5-hydroxytryptamine receptor 4
Serotonin receptor 4
Similar targets:
Uniprot name% Sequence similarity% Sequence identity
Q546Q1_HUMAN100100
Q8IXH9_HUMAN10099.7
Q684M0_HUMAN94.393.3
Q712M9_HUMAN90.790.7
ADRB2_HUMAN46.131.7
DRD1_HUMAN45.331.1
HRH2_HUMAN45.131.5
TAAR1_HUMAN44.229.7
Q7Z5R9_HUMAN44.130.7
5HT6R_HUMAN43.428.1
AA1R_HUMAN43.226
5HT2C_HUMAN43.127.8
ADRB3_HUMAN4328.2
DRD5_HUMAN42.829.3
AA3R_RAT42.326.3
Q3U4C5_MOUSE42.126
AA3R_MOUSE42.125.5
Q4PKD9_RAT42.126
5HT1F_HUMAN41.628.3
Q9P2Q4_HUMAN41.628.3
B1WBR3_RAT41.126.3
AA3R_HUMAN4125.2
OPRD_HUMAN40.424.5
Q5VX04_HUMAN40.228
Q6NUP5_HUMAN40.123
AGTR1_HUMAN40.123
Q53YY0_HUMAN40.123
Q8TBK4_HUMAN40.123
MTR1A_HUMAN39.923
DRD3_HUMAN39.925.9
Protein-Protein Interactions: