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Target Details

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Name:5-HT-1B
Uniprot name:5HT1B_HUMAN
Accession Numbers:P28222 Q4VAY7
EC-Number:-
Organism:Homo sapiens
Human
PDB IDs:2G1X
KEGG Pathways:show KEGG Pathways
Drugs:
NamePubChem IDSourceReferencesInteraction
1,3-Propanediamine, N,N-dimethyl-N'-phenyl-547517BindingDB-show
1-(2-aminopropyl)-2H-indazol-6-one9834183BindingDB-show
1-(2-isochroman-1-ylethyl)-4-(4-methoxyphenyl)piperazine9863333BindingDB-show
1-Methyl-2-benzylimidazoline47570BindingDB-show
1-Naphthylpiperazine1342BindingDB-show
1-sulfonylindazole, 6c23624307BindingDB-show
1-sulfonylindazole, 7a24771120BindingDB-show
1-sulfonylindazole, 7b25263302BindingDB-show
1-TIP-4-FEP6426760BindingDB-show
1H-Indole,6426761BindingDB-show
2-(2-naphthalen-1-yloxyethylamino)ethanol2261792BindingDB-show
2-(4-tert-butyl-2,6-dimethylphenyl)ethanamine2574642BindingDB-show
2-(naphthalen-1-yloxy)ethanamine14519851BindingDB-show
2-ABI225047BindingDB-show
2-[(2,4,6-trimethylphenyl)methyl]-4,5-dihydro-1H-imidazole3016908BindingDB-show
2-[4-[4-(3-methoxyphenyl)piperazin-1-yl]butyl]-4-methyl-1,2,4-triazine-3,511948707BindingDB-show
5-(Nonyloxy)tryptamine1797BindingDB-show
5-methoxy-3-[(1-methylpyrrolidin-2-yl)methyl]-1H-indole10060391BindingDB-show
5-Propoxytryptamine10751317BindingDB-show
6-amino-6,7,8,9-tetrahydro-5H-carbazole-3-carboxamide127036BindingDB-show
6-Methoxyharmalan5474706BindingDB-show
7-Methoxy-1,2,3,4-tetrahydro-9H-pyrido[3,4-b]indole599482BindingDB-show
8-OH-Dpat1220BindingDB-show
9-[[4-(4-fluorophenyl)piperazin-1-yl]methyl]-5,7-diazabicyclo[4.3.0]nona-210267394BindingDB-show
AC1LP9Z61328538BindingDB-show
AC1M3YRE2199302BindingDB-show
AC1MTLTN3604129BindingDB-show
AC1Q41AN22067856BindingDB-show
Acetryptine20810BindingDB-show
Almotriptan123606DrugBank-show
Almotriptan123606SuperTargetPMID 12831340show
Betapindol4828BindingDB-show
Betapindol4828DrugBank-show
Betapindol4828SuperTarget2 PMIDsshow
Butanamine, N-ethyl-N-2-1-naphthyloxy;ethyl-6422277BindingDB-show
CBDivE_015930188006BindingDB-show
CHEBI:42323244400751BindingDB-show
CHEBI:42334344400792BindingDB-show
CHEBI:42366344400916BindingDB-show
CHEBI:42369344400930BindingDB-show
CHEBI:482952107BindingDB-show
CHEMBL10168611728004BindingDB-show
CHEMBL10225011120893BindingDB-show
CHEMBL10342422611622BindingDB-show
CHEMBL10347910020895BindingDB-show
CHEMBL10350310904295BindingDB-show
CHEMBL10355011810310BindingDB-show
CHEMBL10415810891048BindingDB-show
CHEMBL10437410198756BindingDB-show
CHEMBL10448411824522BindingDB-show
CHEMBL10469210872581BindingDB-show
CHEMBL10472011011968BindingDB-show
CHEMBL10475311046087BindingDB-show
CHEMBL10502511035452BindingDB-show
CHEMBL10509110925382BindingDB-show
CHEMBL10511811047115BindingDB-show
CHEMBL10532711822996BindingDB-show
CHEMBL10536910970604BindingDB-show
CHEMBL10555611809037BindingDB-show
CHEMBL10572211110452BindingDB-show
CHEMBL10574311067619BindingDB-show
CHEMBL10595811759467BindingDB-show
CHEMBL10597044337713BindingDB-show
CHEMBL10680744337730BindingDB-show
CHEMBL10748710663236BindingDB-show
CHEMBL10761710664203BindingDB-show
CHEMBL10777244337697BindingDB-show
CHEMBL1083379881478BindingDB-show
CHEMBL10839510830159BindingDB-show
CHEMBL10864519066199BindingDB-show
CHEMBL10872219066204BindingDB-show
CHEMBL10881810517352BindingDB-show
CHEMBL10936044339071BindingDB-show
CHEMBL10983910640199BindingDB-show
CHEMBL11031810710400BindingDB-show
CHEMBL11060119066234BindingDB-show
CHEMBL11094212361789BindingDB-show
CHEMBL11110710496545BindingDB-show
CHEMBL1111509928474BindingDB-show
CHEMBL11128310828231BindingDB-show
CHEMBL11128410567450BindingDB-show
CHEMBL11130219066162BindingDB-show
CHEMBL11137610848041BindingDB-show
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CHEMBL36979844383737BindingDB-show
CHEMBL36999711209208BindingDB-show
CHEMBL37011011568826BindingDB-show
CHEMBL37012844404394BindingDB-show
CHEMBL37109444405587BindingDB-show
CHEMBL3712219933975BindingDB-show
CHEMBL37231211311148BindingDB-show
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CHEMBL38112711299968BindingDB-show
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CHEMBL39127144431532BindingDB-show
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CHEMBL39258622115679BindingDB-show
CHEMBL39277044438464BindingDB-show
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CHEMBL39316944438469BindingDB-show
CHEMBL39920311304851BindingDB-show
CHEMBL40214344455426BindingDB-show
CHEMBL41442010590370BindingDB-show
CHEMBL4166889803620BindingDB-show
CHEMBL4184411801562BindingDB-show
CHEMBL41882310498633BindingDB-show
CHEMBL41954710915350BindingDB-show
CHEMBL42019110383010BindingDB-show
CHEMBL42047510946905BindingDB-show
CHEMBL42074810475893BindingDB-show
CHEMBL4208749930155BindingDB-show
CHEMBL42096510386282BindingDB-show
CHEMBL4209979910451BindingDB-show
CHEMBL42157311145333BindingDB-show
CHEMBL42219110759465BindingDB-show
CHEMBL42219244376362BindingDB-show
CHEMBL42236610834909BindingDB-show
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CHEMBL42899144376262BindingDB-show
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CHEMBL44855524882268BindingDB-show
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CHEMBL8119110070281BindingDB-show
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CHEMBL8248844461298BindingDB-show
CHEMBL8252344461586BindingDB-show
CHEMBL8311244461335BindingDB-show
CHEMBL836179802187BindingDB-show
CHEMBL8373244461425BindingDB-show
CHEMBL8417144461306BindingDB-show
CHEMBL8430544461308BindingDB-show
CHEMBL921399862256BindingDB-show
CHEMBL938689927441BindingDB-show
CHEMBL9392311049209BindingDB-show
CHEMBL9461211826976BindingDB-show
CHEMBL9517511092112BindingDB-show
CHEMBL9718411827039BindingDB-show
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CHEMBL9733311071135BindingDB-show
CHEMBL9742211123573BindingDB-show
CHEMBL9765010972931BindingDB-show
CHEMBL982419845181BindingDB-show
CHEMBL9829911092142BindingDB-show
CID 1004496510044965BindingDB-show
CID 1014106611260311BindingDB-show
CID 1036536411743399BindingDB-show
CID 1040186210401862BindingDB-show
CID 1040186210424220BindingDB-show
CID 1040186210062659BindingDB-show
CID 1044847010064361BindingDB-show
CID 1044847011723305BindingDB-show
CID 1050409510504095BindingDB-show
CID 1050409510575878BindingDB-show
CID 1050409610551857BindingDB-show
CID 1050409610504096BindingDB-show
CID 1050552510720175BindingDB-show
CID 1050552510505525BindingDB-show
CID 1052664210502763BindingDB-show
CID 1052664210526642BindingDB-show
CID 1052788210527882BindingDB-show
CID 1052788210813769BindingDB-show
CID 1055538310326069BindingDB-show
CID 1069314010693140BindingDB-show
CID 1069314010501945BindingDB-show
CID 1076632010766320BindingDB-show
CID 1076632010766321BindingDB-show
CID 1085856610468376BindingDB-show
CID 1085856610858566BindingDB-show
CID 1174304311743042BindingDB-show
CID 17808110870264BindingDB-show
CID 1780819948210BindingDB-show
CID 178081178081BindingDB-show
CID 69186016918601BindingDB-show
CID 97948099794809BindingDB-show
CID 98307419830741BindingDB-show
CID 98560419856041BindingDB-show
CID 98948189894818BindingDB-show
CID 99812709981270BindingDB-show
CID 999467410379784BindingDB-show
CID 99946749994674BindingDB-show
CID 999467410402263BindingDB-show
CID 99974219997421BindingDB-show
CID 999742110065919BindingDB-show
CID 99974219997422BindingDB-show
CID53112585311258BindingDB-show
Cornutamine8223DrugBank-show
Cornutamine8223SuperTargetPMID 014504136show
CPMPP-35311200BindingDB-show
Dexpropranolol4946BindingDB-show
Dexpropranolol4946DrugBank-show
Dexpropranolol4946SuperTarget2 PMIDsshow
Dextrofenfluramine3337DrugBank-show
Dihydroergotamine monomethanesulfonate10531DrugBank-show
Dihydroergotamine monomethanesulfonate10531SuperTargetPMID 008973575show
Dihydroharman5316718BindingDB-show
Eletriptan77993DrugBank-show
Eletriptan77993SuperTarget2 PMIDsshow
Frovatriptan77992BindingDB-show
Frovatriptan77992DrugBank-show
Frovatriptan77992SuperTargetPMID 15185063show
GR 127935 hydrochloride107780BindingDB-show
GR 466116160690BindingDB-show
Ketanserinum3822BindingDB-show
Leucoharmine5280953BindingDB-show
Levopenbutol37464SuperTargetPMID 9225271show
MAZAPERTINE60820BindingDB-show
Methergoline28693SuperTargetPMID 009760032show
Methoxydimethyltryptamines1832BindingDB-show
Methoxytryptamine1833BindingDB-show
Methyl(2-Phenoxyethyl)Amine37732BindingDB-show
Methylmethylergonovine9681SuperTargetPMID 010188968show
Minaprine dihydrochloride4199SuperTargetPMID 002583235show
Minaprine dihydrochloride33254SuperTargetPMID 002583235show
N,N-dimethyl-2-(5-propan-2-yl-1H-indol-3-yl)ethanamine2762737BindingDB-show
N,N-Dimethyl-3-phenoxypropylamine210076BindingDB-show
N-imidazolidin-2-ylideneaniline137235BindingDB-show
N-[9-(1-methyl-4-piperidyl)-2,7-diazabicyclo[4.3.0]nona-2,4,8,10-tetraen-39947817BindingDB-show
Naratriptan4440BindingDB-show
Naratriptan4440DrugBank-show
NCGC00025153-016604864BindingDB-show
nchembio873-comp523378093BindingDB-show
Oprea1_4055432760172BindingDB-show
Oximetazolinum4636BindingDB-show
p-Iodoclonidine hydrochloride4656BindingDB-show
PDSP1_0003726918542BindingDB-show
PDSP1_00138910331436BindingDB-show
Phenylmethylimidazoline5504BindingDB-show
Risatriptan5078BindingDB-show
Risatriptan5078DrugBank-show
rizatriptan77997SuperTarget-show
S1546_Selleck11243002BindingDB-show
sertindole hydrochloride60149BindingDB-show
Sumatriptanum5358BindingDB-show
Sumatriptanum5358DrugBank-show
Sumatriptanum5358SuperTarget2 PMIDsshow
TDBIA129503BindingDB-show
Terazosin hydrochloride4893BindingDB-show
TERTATOLOL36920SuperTargetPMID 8905706show
Thrombocytin5202BindingDB-show
Tocris-1032124007BindingDB-show
Tocris-1054128018BindingDB-show
Tryptamine hydrochloride1150BindingDB-show
VenlafaxineXR5656DrugBank-show
WAY-25680524894910BindingDB-show
Xylomethazoline5709BindingDB-show
Xylonidine78576BindingDB-show
Zolmitriptan60857BindingDB-show
Zolmitriptan441240DrugBank-show
zolmitriptan5731DrugBank-show
Zolmitriptan60857DrugBank-show
Zolmitriptan60857SuperTargetPMID 009859690show
Zolmitriptan441240SuperTargetPMID 009859690show
zolmitriptan5731SuperTargetPMID 009859690show
Synonyms:
5-HT-1B
5-HT-1D-beta
5-HT1B
5-hydroxytryptamine receptor 1B
S12
Serotonin 1D beta receptor
Serotonin receptor 1B
Similar targets:
Uniprot name% Sequence similarity% Sequence identity
5HT1D_HUMAN74.460.6
5HT1F_HUMAN61.645
Q9P2Q4_HUMAN61.344.7
5HT1E_HUMAN56.842.5
Q5ZGX3_HUMAN54.938.6
5HT1A_HUMAN54.938.6
5HT5A_HUMAN49.833.3
DRD3_HUMAN46.331.8
DRD4_MOUSE4630
Q59EH9_HUMAN4430.9
ADA2C_HUMAN43.228.6
DRD2_RAT42.129.5
ADA2A_HUMAN42.129.4
HRH4_HUMAN41.723.9
ADRB3_HUMAN41.428.7
ADRB2_HUMAN41.325.6
5HT2B_HUMAN40.823.1
5HT2A_HUMAN40.724.2
DRD2_HUMAN40.628.2
5HT7R_HUMAN40.428
Q5VX04_HUMAN40.428
Q5VX03_HUMAN40.428
ADA2B_HUMAN40.225.4
HRH1_HUMAN40.225.5
5HT2C_HUMAN40.224.5
ACM1_HUMAN39.625.6
ACM2_HUMAN39.624.8
DRD2_MOUSE39.527.4
HRH1_BOVIN39.525.9
ADA1A_HUMAN39.226.2
Protein-Protein Interactions: