Home
Drugs
Targets
Pathways
Ontologies
Cyp450s
Adv.search
Help/FAQ

Drug-Target Interaction

Drug

show drug details
PubChem ID:9977819
Structure:
Synonyms:
405169-16-6
CHEBI:594834
EC-000.2257
S1018_Selleck
TKI-258, Dovitinib, CHIR258, TKI258
UNII-I35H55G906

Target

show target details
Uniprot ID:MK10_HUMAN
Synonyms:
c-Jun N-terminal kinase 3
MAP kinase p49 3F12
Mitogen-activated protein kinase 10
Stress-activated protein kinase JNK3
EC-Numbers:2.7.11.24
Organism:Homo sapiens
Human
PDB IDs:1JNK 1PMN 1PMQ 1PMU 1PMV 2B1P 2EXC 2O0U 2O2U 2OK1 2P33 2R9S 2WAJ 2ZDT 2ZDU 3CGF 3CGO 3DA6 3FI2 3FI3 3FV8 3G90 3G9L 3G9N
Structure:
3G9N

Binding Affinities:

Ki: Kd:Ic 50:Ec50/Ic50:
->10000--

References: