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Drug-Target Interaction

Drug

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PubChem ID:9977819
Structure:
Synonyms:
405169-16-6
CHEBI:594834
EC-000.2257
S1018_Selleck
TKI-258, Dovitinib, CHIR258, TKI258
UNII-I35H55G906

Target

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Uniprot ID:MET_HUMAN
Synonyms:
c-Met
Hepatocyte growth factor receptor
HGF receptor
HGF/SF receptor
Met proto-oncogene tyrosine kinase
Scatter factor receptor
SF receptor
EC-Numbers:2.7.10.1
Organism:Homo sapiens
Human
PDB IDs:1FYR 1R0P 1R1W 1SHY 1SSL 1UX3 2G15 2RFN 2RFS 2UZX 2UZY 2WD1 2WGJ 3BUX 3CE3 3CTH 3CTJ 3EFJ 3EFK 3F66 3F82
Structure:
3F82

Binding Affinities:

Ki: Kd:Ic 50:Ec50/Ic50:
->10000--

References: