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Drug-Target Interaction

Drug

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PubChem ID:9886249
Structure:
Synonyms:
5-(4-amino-5,8-difluoro-spiro[1H-quinazoline-2,4'-piperidine]-1'-carbonyl)
5-(4-Amino-5,8-difluorospiro[1H-quinazoline-2,4'-piperidine]-1'-carbonyl)pyridine-2-carbonitrile
AR-C102222
CHEBI:285000
CHEMBL447183
CID9886249
DB07405
nchembio.115-comp3

Target

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Uniprot ID:NOS3_HUMAN
Synonyms:
cNOS
Constitutive NOS
EC-NOS
Endothelial NOS
eNOS
Nitric oxide synthase, endothelial
NOS type III
NOSIII
EC-Numbers:1.14.13.39
Organism:Homo sapiens
Human
PDB IDs:1M9J 1M9K 1M9M 1M9Q 1M9R 3EAH 3NOS
Structure:
3NOS

Binding Affinities:

Ki: Kd:Ic 50:Ec50/Ic50:
-->100000-

References: