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Drug-Target Interaction

Drug

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PubChem ID:94320
Structure:
Synonyms:
(2S,4aS,6aR,6aS,6bR,8aR,10S,12aS,14bR)-10-acetyloxy-2,4a,6a,6b,9,9,12a-hep
(3-beta,20-beta)-3-(Acetyloxy)-11-oxo-olean-12-en-29-oic acid
(3beta,20beta)-3-Acetoxy-11-oxoolean-12-en-29-oic acid
29728-34-5
29728-34-5 (aluminum salt)
3-Acetyl-18-beta-glycyrrhetinic acid
6277-14-1
AC1L3RZB
AC1Q5QZD
Acetoxolone
Acetylglycyrrhetic acid
Acetylglycyrrhetinic acid
AR-1K9243
C17734
C32H48O5
CHEBI:448947
CHEMBL207413
EINECS 228-475-1
Glycyrrhetic acid acetate
Glycyrrhetinic acid acetate
Glycyrrhetinyl acetate
LS-98287
NSC 35349
NSC35349
Olean-12-en-29-oic acid, 3-(acetyloxy)-11-oxo-, (3-beta,20-beta)-
Olean-12-en-30-oic acid, 3-beta-hydroxy-11-oxo-, acetate (7CI,8CI)
Oriens
ATC-Codes:

Target

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Uniprot ID:DHI1_HUMAN
Synonyms:
11-beta-HSD1
11-beta-hydroxysteroid dehydrogenase 1
11-DH
Corticosteroid 11-beta-dehydrogenase isozyme 1
EC-Numbers:1.1.1.146
Organism:Homo sapiens
Human
PDB IDs:1XU7 1XU9 2BEL 2ILT 2IRW 2RBE 3BYZ 3BZU 3CH6 3CZR 3D3E 3D4N 3D5Q 3EY4 3FRJ
Structure:
3FRJ

Binding Affinities:

Ki: Kd:Ic 50:Ec50/Ic50:
--800-
--3450-
--7138-

References: