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Drug-Target Interaction

Drug

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PubChem ID:932
Structure:
Synonyms:
( )-Naringenin; 4?,5,7-Trihydroxyflavanone; H-1-benzopyran-4-one
()-2,3-Dihydro-5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one
()-Naringenin
()-oxazepam hemisuccinate sodium salt
(+/-)-2,3-Dihydro-5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one
(+/-)-Naringenin
(-)-Naringenin
(2S)-5,7-dihydroxy-2-(4-hydroxyphenyl)chroman-4-one
(S)-2,3-Dihydro-5,7-dihydroxy-2-(4-hydroxyphenyl)-4-benzopyrone
(S)-2,3-Dihydro-5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one
(S)-Naringenin
4',5,7-Trihydroxyflavanone
480-41-1
4H-1-Benzopyran-4-one, 2,3-dihydro-5,7-dihydroxy-2-(4-hydroxyphenyl)-
4H-1-Benzopyran-4-one, 2,3-dihydro-5,7-dihydroxy-2-(4-hydroxyphenyl)-,
4H-1-Benzopyran-4-one, 2,3-dihydro-5,7-dihydroxy-2-(4-hydroxyphenyl)-, (S)-
5,7-dihydroxy-2-(4-hydroxyphenyl)-2,3-dihydro-4H-chromen-4-one
5,7-Dihydroxy-2-(4-hydroxyphenyl)chroman-4-one
67604-48-2
ACon1_000582
AI3-23355
BE 14348A
BE-14348A
BPBio1_000630
BSPBio_000572
C15H12O5
CCRIS 5839
CHEBI:50202
DB03467
EINECS 207-550-2
EINECS 266-769-1
Flavanone, 4',5,7-trihydroxy-
Flavanone, 4',5,7-trihydroxy- (8CI)
LS-39547
LS-5089
MEGxp0_000358
MLS000028739
MLS000738094
MLS001146907
N5893_ALDRICH
N5893_SIGMA
NARIGENIN
NARINGENIN
Naringenin (NAR)
naringenin-7-sulfate
Naringenine
Naringetol
NCGC00095963-01
NCGC00095963-02
NCGC00095963-03
NSC 11855
NSC 34875
NSC11855
NSC34875
Oprea1_194140
Prestwick0_000466
Prestwick1_000466
Prestwick2_000466
Prestwick3_000466
Prestwick_531
S00279
Salipurol
Salipurpol
SBB006461
SMP1_000060
SMR000059039
SPBio_002511

Target

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Uniprot ID:DHB1_HUMAN
Synonyms:
17-beta-HSD 1
17-beta-hydroxysteroid dehydrogenase type 1
20 alpha-hydroxysteroid dehydrogenase
20-alpha-HSD
E2DH
Estradiol 17-beta-dehydrogenase 1
Placental 17-beta-hydroxysteroid dehydrogenase
EC-Numbers:1.1.1.62
Organism:Homo sapiens
Human
PDB IDs:1A27 1BHS 1DHT 1EQU 1FDS 1FDT 1FDU 1FDV 1FDW 1I5R 1IOL 1JTV 1QYV 1QYW 1QYX 3DHE
Structure:
3DHE

Binding Affinities:

Ki: Kd:Ic 50:Ec50/Ic50:
--4960-

References: