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Drug-Target Interaction

Drug

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PubChem ID:795
Structure:
Synonyms:
1,3-Diaza-2,4-cyclopentadiene
1,3-Diaza-2,4-cyclopentadiene-
1,3-Diazole
116421-26-2
146117-15-9
1467-16-9
1467-16-9 (mono-hydrochloride)
1H-Imidazole
1H-Imidazole (9CI)
288-32-4
4286D518-643C-4C69-BCE7-519D073F4992
5-23-04-00191 (Beilstein Handbook Reference)
5587-42-8
5587-42-8 (hydrochloride salt)
56748_FLUKA
56748_SIGMA
56749_FLUKA
56749_SIGMA
56750_FLUKA
56750_SIAL
68268_FLUKA
68268_SIGMA
AB1002136
AC1L1A1H
AC1Q4W12
AC1Q4W13
AG-E-93194
AI3-24703
AIDS-008702
AIDS008702
AKOS000120177
BB_SC-6938
bmse000096
BRN 0103853
C01589
C3H4N2
CCRIS 3345
CHEBI:16069
CHEMBL540
EINECS 206-019-2
Formamidine, N,N'-vinylene-
Glioksal
Glioksal [Polish]
Glyoxalin
Glyoxaline
Glyoxaline solution
Him
I0001
I0014
I0125_SIGMA
I0250_SIGMA
I0288
I0290
I14-0665
I14-10573
I2399_SIAL
I5513_SIGMA
IMD
Imidazol
imidazole
Imidazole (8CI)
Imidazole buffer Solution
Imidazole solution
IMIDAZOLE-RING
Iminazole
Imutex
LS-77964
Methanimidamide, N,N'-1,2-ethenediyl-
Miazole
MLS001055465
MolPort-000-156-418
N,N'-1,2-ethenediylmethanimidamide
N,N'-vinyleneformamidine
NCGC00090984-01
NCGC00090984-02
nchem.892-comp5
NCIStruc1_001975
NCIStruc2_000693
NSC 51860
NSC 60522
NSC51860
NSC60522
Pyrro(b)monazole
Pyrro[b]monazole
SMR000057825
ST097249
ST5214389
STK362967
TL8002274
Unavailable - See ASDI_CatNo 500012277
Usaf ek-4733
WLN: T5M CNJ
ZINC00901039

Target

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Uniprot ID:PIM1_HUMAN
Synonyms:
Proto-oncogene serine/threonine-protein kinase Pim-1
EC-Numbers:2.7.11.1
Organism:Homo sapiens
Human
PDB IDs:1XQZ 1XR1 1XWS 1YHS 1YI3 1YI4 1YWV 1YXS 1YXT 1YXU 1YXV 1YXX 2BIK 2BIL 2BZH 2BZI 2BZJ 2BZK 2C3I 2J2I 2O3P 2O63 2O64 2O65 2OBJ 2OI4 3BGP 3BGQ 3BGZ 3BWF 3C4E 3CXW 3CY2 3CY3 3DCV 3F2A
Structure:
3F2A

Binding Affinities:

Ki: Kd:Ic 50:Ec50/Ic50:
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References: