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Drug-Target Interaction

Drug

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PubChem ID:77999
Structure:
Synonyms:
122320-73-4
2,4-Thiazolidinedione,
2,4-Thiazolidinedione, 5-((4-(2-(methyl-2-pyridinylamino)ethoxy)phenyl)methyl)-
2,4-Thiazolidinedione, 5-004-02-((((methyl-2-pyridinylamino)ethoxy)phenyl)methyl)-
2,4-thiazolidinedione, 5-[[4-[2-(methyl-2-pyridinylamino)ethoxy]phenyl]methyl]-
2,4-Thiazolidinedione, 5-[[4-[2-(methyl-2-pyridinylamino)ethoxy]phenyl]methyl]- (9CI)
5-((4-(2-(methyl-2-pyridinylamino)ethoxy)phenyl)methyl)-2,4-thiazolidinedione
5-((4-(2-Methyl-2-(pyridinylamino)ethoxy)phenyl)methyl)-2,4-thiazolidinedione-2-butenedioate
5-(4-{2-[methyl(pyridin-2-yl)amino]ethoxy}benzyl)-1,3-thiazolidine-2,4-dione
5-[4-[2-(N-Methyl-N-(2-pyridyl)amino)ethoxy]benzyl]thiazolidine-2,4-dione
5-[[4-[2-(methyl-(2-pyridyl)amino)ethoxy]phenyl]methyl] thiazolidine-2,4-dione
5-[[4-[2-(methyl-pyridin-2-ylamino)ethoxy]phenyl]methyl]-1,3-thiazolidine-2,4-dione
Avandaryl
Avandia
BB_SC-4138
Brl 49653
Brl-49653
BRL49653
BSPBio_002693
C18H19N3O3S
CHEBI:50122
DB00412
IDMB (1uM BRL49653, 1uM Dexamethasone, 0.5uM IBMX, 10ug/mL Insulin)
KBio2_002183
KBio2_004751
KBio2_007319
KBio3_001913
KBioGR_001609
KBioSS_002183
LS-151340
NCGC00095124-01
NCGC00095124-02
NCGC00095124-03
RGZ
Rosi
Rosigilitazone
Rosigliazone maleate
Rosiglitazone
rosiglitazone (Avandia)
Rosiglitazone maleate
Rosiglitazone [INN:BAN]
Rosiglizole
RSG
S00306
SPBio_001142
SPECTRUM1504263
Spectrum2_001241
Spectrum3_000997
Spectrum4_001125
Spectrum5_001464
Spectrum_001703
TDZ 01
[3H]rosiglitazone
ATC-Codes:
Side-Effects:
Side-EffectFrequency
abdominal pain0.0010
hyperbilirubinemia0.0010
hyperglycemia0.0010
hypoglycemia0.0010
influenza0.0010
nasopharyngitis0.0010
nausea0.0010
pain0.0010
pleural effusions0.0010
pruritus0.0010
pulmonary edema0.0010
sinusitis0.0010
stevens - johnson syndrome0.0010
upper respiratory tract infection0.0010
urticaria0.0010
vomiting0.0010
hepatic failure0.0010
hepatitis0.0010
congestive heart failure0.0010
cardiac failure0.0010
anaphylactic reaction0.0010
anemia0.0010
angioedema0.0010
back pain0.0010
cough0.0010
type 2 diabetes0.0010
diabetic ketoacidosis0.0010
diarrhea0.0010
dizziness0.0010
dysmenorrhea0.0010
headache0.0010
edema0.0010
rash0.0010
weight gain0
fatigue0
hypertension0
arthralgia0
constipation0
myocardial infarction0
myocardial ischemia0

Target

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Uniprot ID:CP2CJ_HUMAN
Synonyms:
(R)-limonene 6-monooxygenase
(S)-limonene 6-monooxygenase
(S)-limonene 7-monooxygenase
CYPIIC17
CYPIIC19
Cytochrome P450 2C19
Mephenytoin 4-hydroxylase
P450-11A
P450-254C
EC-Numbers:1.14.13.48
1.14.13.49
1.14.13.80
Organism:Homo sapiens
Human
PDB IDs:-

Binding Affinities:

Ki: Kd:Ic 50:Ec50/Ic50:
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References: