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Drug-Target Interaction

Drug

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PubChem ID:72474
Structure:
Synonyms:
(+-)-1-Cyclopropyl-6-fluoro-1,4-dihydro-5-methyl-7-(3-methyl-1-piperazinyl)-4-oxo-3-quinolinecarboxylic acid
(+/-)-3-Quinolinecarboxylic acid, 1-cyclopropyl-6-fluoro-1,4-dihydro-5-methyl-7-(3-methyl-1-piperazinyl)-4-oxo-
1-Cyclopropyl-6-fluoro-1,4-dihydro-5-methyl-7-(3-methyl-1-piperazinyl)-4-o
1-Cyclopropyl-6-fluoro-1,4-dihydro-5-methyl-7-(3-methyl-1-piperazinyl)-4-oxo-3-quinolinecarboxylic acid
1-cyclopropyl-6-fluoro-5-methyl-7-(3-methylpiperazin-1-yl)-4-oxoquinoline-3-carboxylic acid
119914-60-2
126292-40-8
146863-02-7
161967-81-3 (MONOHYDROCHLORIDE)
3-Quinolinecarboxylic acid, 1,4-dihydro-1-cyclopropyl-6-fluoro-5-methyl-7-(3-methyl-1-piperazinyl)-4-oxo-
3-Quinolinecarboxylic acid, 1-cyclopropyl-6-fluoro-1,4-dihydro-5-methyl-7-(3-methyl-1-piperazinyl)-4-oxo-
AIDS-008528
AIDS008528
C11368
C19H22FN3O3
CCRIS 7284
DB00365
Grepafloxacin
Grepafloxacin (unspecified)
Grepafloxacin [INN]
LS-141560
NCGC00167527-01
OPC-17116
Raxar
ATC-Codes:

Target

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Uniprot ID:GYRB_ECOLI
Synonyms:
DNA gyrase subunit B
EC-Numbers:5.99.1.3
Organism:Escherichia coli
strain K12
PDB IDs:1AJ6 1EI1 1KZN
Structure:
1KZN

Binding Affinities:

Ki: Kd:Ic 50:Ec50/Ic50:
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References: