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Drug-Target Interaction

Drug

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PubChem ID:71273
Structure:
Synonyms:
(+-)-ropivacaine
(-)-1-Propyl-2',6'-dimethyl-2-piperidylcarboxyanilid
(-)-1-Propyl-2',6'-pipecoloxylidide
1-propyl-2',6'-dimethyl-2-piperidylcarboxyanilide
1-propyl-2',6'-pipecoloxylidide
84057-95-4
AB1004866
AC-6967
AC1L2FVE
AC1Q5LX3
AL 381
AL-381
AR-1J7531
C17H26N2O
CHEBI:60802
CID71273
DB00296
DL-ropivacaine
I01-1870
LEA 103
LEA-103
LS-177798
N-(2,6-dimethylphenyl)-1-propyl-piperidine-2-carboxamide
N-(2,6-dimethylphenyl)-1-propylpiperidine-2-carboxamide
N-n-propylpipecolic acid-2,6-xylidide
NAROPIN
rac-ropivacaine
racemic ropivacaine
Ropivacaina
Ropivacaina [INN-Spanish]
Ropivacaina [Spanish]
Ropivacaine
ROPIVACAINE HYDROCHLORIDE MONOHYDRATE
Ropivacaine [INN]
Ropivacainum
Ropivacainum [INN-Latin]
S-Ropivacaine
UNII-7IO5LYA57N
ATC-Codes:
Side-Effects:
Side-EffectFrequency
nervousness0
syncope0
tachycardia0
thrombocytopenia0
tinnitus0
tremor0
unconsciousness0
loss of consciousness0
erythema0
urinary incontinence0
urinary tract infection0
urticaria0
vasovagal reaction0
sneezing0
shock0
seizures0
nightmares0
weakness0
paresthesia0
phlebitis0
pleural effusion0
puncture0
ptosis0
pruritus0
pulmonary embolism0
purpura0
pyuria0
rhinitis0
ventricular fibrillation0
ventricular tachycardia0
myalgia0
tenesmus0
excitement0
hypoxia0
epidural abscess0
blurred vision0
bradycardia0
neuropathy0
paralysis0
increased sweating0
thrombocythemia0
insomnia0
malaise0
respiratory arrest0
hypoglycaemia neonatal0
vertigo0
vomiting0
urinary retention0
chills0
stupor0
agitation0
emotional lability0
peripheral edema0
deep vein thrombosis0
hypomagnesemia0
alkaline phosphatase increased0
sgot increased0
allergic reaction0
abdominal pain0
breast disorders0
bronchospasm0
chest pain0
coma0
confusion0
constipation0
convulsions0
cough0
diarrhea0
dizziness0
somnolence0
dyskinesia0
back pain0
atrial fibrillation0
atelectasis0
acidosis0
albuminuria0
amnesia0
anaphylaxis0
anemia0
angioedema0
anxiety0
apnea0
arachnoiditis0
arrhythmia0
arthralgia0
asthenia0
dyspepsia0
dyspnea0
hypokalemia0
hypotension0
postural hypotension0
hypothermia0
infection0
jaundice0
neonatal jaundice0
leukocytosis0
meningismus0
meningitis0
muscle cramps0
myocardial infarction0
hypocalcemia0
hypertension0
hyperglycemia0
dysuria0
edema0
rash0
fecal incontinence0
fever0
hallucinations0
headache0
cardiac arrest0
heart block0
hematoma0
hematuria0
hemorrhage0
nausea0

Target

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Uniprot ID:Q6GRK0_HUMAN
Synonyms:
cDNA, FLJ93427, Homo sapiens cytochrome P450, family 3, subfamily A, polypeptide 4(CYP3A4), transcript variant 1, mRNA
Cytochrome P450 family 3 subfamily A polypeptide 4
Cytochrome P450, family 3, subfamily A, polypeptide 4
Cytochrome P450, family 3, subfamily A, polypeptide 4, isoform CRA_a
Cytochrome P450, subfamily IIIA, polypeptide 4
EC-Numbers:-
Organism:Homo sapiens
Human
PDB IDs:-

Binding Affinities:

Ki: Kd:Ic 50:Ec50/Ic50:
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References: