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Drug-Target Interaction

Drug

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PubChem ID:71158
Structure:
Synonyms:
3-(Acetylamino)propanesulphonic acid
3-Acetamido-1-propanesulfonic acid
3-acetamidopropane-1-sulfonic acid
77337-70-3
77337-70-3 (mono-hydrochloride salt)
77337-71-4
77337-71-4 (mono-potassium salt)
77337-72-5
77337-72-5 (mono-lithium salt)
77337-73-6
77337-73-6 (calcium[2:1] salt)
77337-74-7
77337-74-7 (magnesium[2:1] salt)
77337-76-9
AC1L2FNA
AC1Q1L6O
AC1Q6X8K
Acamprosate
acamprosate (Campral)
Acamprosate (INN)
Acamprosate 6473
Acamprosate 6473 [INN]
Acamprosate [INN:BAN]
Acamprosato
Acamprosato [INN-Spanish]
Acamprosatum
Acamprosatum [INN-Latin]
acamprostate
AOTA
Aotal
Aotal (TN)
AR-1H6082
C5H11NO4S
calcium acetyl homotaurinate
calcium acetylhomotaurinate
calcium acetylhomotaurine
Campral
CHEBI:51041
CHEMBL1201293
D07058
DB00659
EINECS 278-667-4
HSDB 7358
LS-120940
N-Acetylhomotaurine
sodium acetylhomotaurine
UNII-N4K14YGM3J
ATC-Codes:
Side-Effects:
Side-EffectFrequency
rhinitis1.0
chest pain1.0
suicide attempt1.0
abnormal vision1.0
constipation1.0
cough1.0
chills1.0
dyspepsia1.0
dyspnea1.0
headache1.0
pharyngitis1.0
palpitation1.0
bronchitis1.0
back pain1.0
infection1.0
abdominal pain1.0
flu syndrome1.0
impotence1.0
syncope1.0
rash0.505
vomiting0.505
diarrhea0.14333333
insomnia0.07333333
anxiety0.06333333
asthenia0.060000002
pruritus0.035
dizziness0.035
anorexia0.03333333
pain0.030000001
nausea0.026666665
paresthesia0.025
sweating0.024999999
flatulence0.024999999
dry mouth0.02
migraine0.01
hypotension0.01
lymphocytosis0.01
postural hypotension0.01
dry skin0.01
liver function tests abnormal0.01
leg cramps0.01
sgot increased0.01
liver cirrhosis0.01
myocardial infarct0.01
neurosis0.01
urticaria0.01
vertigo0.01
tinnitus0.01
thrombocytopenia0.01
tachycardia0.01
convulsion0.01
agitation0.01
weight loss0.01
pneumonia0.01
phlebitis0.01
pancreatitis0.01
varicose vein0.01
neuralgia0.01
abscess0.01
dysphagia0.01
exfoliative dermatitis0.01
diabetes mellitus0.01
acne0.01
ecchymosis0.01
eczema0.01
eosinophilia0.01
epistaxis0.01
deafness0.01
confusion0.01
alopecia0.01
amblyopia0.01
anemia0.01
angina pectoris0.01
allergic reaction0.01
asthma0.01
neck pain0.01
hyperuricemia0.01
eructation0.01
esophagitis0.01
fever0.01
gout0.01
hallucinations0.01
hematemesis0.01
malaise0.01
hemorrhage0.01
hepatitis0.01
hernia0.01
bilirubinemia0.01
rectal hemorrhage0.01
hyperglycemia0.01
gastritis0.01
gastroenteritis0.01
gastrointestinal hemorrhage0.01
photophobia0.0010
deep thrombophlebitis0.0010
photosensitivity0.0010
alkaline phosphatase increased0.0010
cardiomyopathy0.0010
urinary urgency0.0010
arterial occlusion0.0010
lymphadenopathy0.0010
mouth ulceration0.0010
lactic dehydrogenase increased0.0010
encephalopathy0.0010
rheumatoid arthritis0.0010
kidney calculus0.0010
hypothyroidism0.0010
carcinoma of liver0.0010
hematuria0.0010
heart failure0.0010
goiter0.0010
edema0.0010
duodenal ulcer0.0010
diplopia0.0010
colitis0.0010
cholecystitis0.0010
ascites0.0010
acute kidney failure0.0010
leukopenia0.0010
torticollis0.0010
stomach ulcer0.0010
increased salivation0.0010
shock0.0010
pulmonary embolus0.0010
psychosis0.0010
psoriasis0.0010
polyuria0.0010
melena0.0010
menorrhagia0.0010
myopathy0.0010
hyponatremia0.0010
nocturia0.0010
somnolence0
amnesia0
tremor0
myalgia0
arthralgia0
manic0
thinking abnormal0
depersonalization0
vaginitis0
peripheral edema0
urinary tract infection0
urinary incontinence0
hypertension0
decreased libido0
metrorrhagia0
weight gain0
nervousness0
urinary frequency0
apathy0

Target

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Uniprot ID:GRM2_HUMAN
Synonyms:
Metabotropic glutamate receptor 2
mGluR2
EC-Numbers:-
Organism:Homo sapiens
Human
PDB IDs:-

Binding Affinities:

Ki: Kd:Ic 50:Ec50/Ic50:
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References: