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Drug-Target Interaction

Drug

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PubChem ID:6918667
Structure:
Synonyms:
8-chloro-6-phenyl-spiro[1,3-dihydroquinazoline-4,1'-cyclohexane]-2-one
8-chloro-6-phenylspiro[1,3-dihydroquinazoline-4,1'-cyclohexane]-2-one
AC1OCFPT
CHEBI:407715
CHEMBL182703
CID6918667

Target

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Uniprot ID:PDE5A_HUMAN
Synonyms:
CGB-PDE
cGMP-binding cGMP-specific phosphodiesterase
cGMP-specific 3',5'-cyclic phosphodiesterase
EC-Numbers:3.1.4.35
Organism:Homo sapiens
Human
PDB IDs:1RKP 1T9R 1T9S 1TBF 1UDT 1UDU 1UHO 1XOZ 1XP0 2CHM 2H40 2H42 2H44 3B2R 3BJC 3HC8 3HDZ
Structure:
3HDZ

Binding Affinities:

Ki: Kd:Ic 50:Ec50/Ic50:
--69800.0-

References: