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Drug-Target Interaction

Drug

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PubChem ID:675226
Structure:
Synonyms:
()-oxazepam hemisuccinate sodium salt
(2-Phenyl-quinazolin-4-yl)-pyridin-3-ylmethyl-amine
(2-phenylquinazolin-4-yl)(3-pyridylmethyl)amine
2-phenyl-N-(pyridin-3-ylmethyl)quinazolin-4-amine
AC1LDTX8
AKOS000536205
BAS 02140101
CHEBI:295819
CHEMBL420539
EU-0009316
HMS1423H01
IFLab1_004027
MLS000568306
MolPort-000-661-490
Oprea1_165476
Oprea1_427229
SMR000177400
ST053724
STK970112
STOCK2S-61186
ZINC00037984

Target

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Uniprot ID:PDE5A_HUMAN
Synonyms:
CGB-PDE
cGMP-binding cGMP-specific phosphodiesterase
cGMP-specific 3',5'-cyclic phosphodiesterase
EC-Numbers:3.1.4.35
Organism:Homo sapiens
Human
PDB IDs:1RKP 1T9R 1T9S 1TBF 1UDT 1UDU 1UHO 1XOZ 1XP0 2CHM 2H40 2H42 2H44 3B2R 3BJC 3HC8 3HDZ
Structure:
3HDZ

Binding Affinities:

Ki: Kd:Ic 50:Ec50/Ic50:
--8600-

References: