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Drug-Target Interaction

Drug

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PubChem ID:65064
Structure:
Synonyms:
(−)-cis-2-(3,4,5-Trihydroxyphenyl)-3,4-dihydro-1(2H)-benzopyran-3,5,7-triol 3-gallate
(−)-cis-3,3',4',5,5',7-Hexahydroxy-flavane-3-gallate
(−)-Epigallocatechin gallate
()-oxazepam hemisuccinate sodium salt
(-)-cis-2-(3,4,5-Trihydroxyphenyl)-3,4-dihydro-1(2H)-benzopyran-3,5,7-triol 3-gallate
(-)-cis-3,3',4',5,5',7-Hexahydroxy-flavane-3-gallate
(-)-EGCG
(-)-epigallocatechin 3-gallate
(-)-Epigallocatechin gallate
(-)-Epigallocatechin gallate (85% (-)-epigallocatechin gallate, 10% (-)-epigallocatechin, 5% (-)- epicatechin gallate)
(-)-EPIGALLOCATECHIN GALLATE (GREEN TEA EXTRACT)
(-)-Epigallocatechin-3-o-gallate
(-)-Epigallocatechol gallate
(2R,3R)-2-(3,4,5-Trihydroxyphenyl)-3,4-dihydro-1[2H]-benzopyran-3,5,7-triol-3-(3,4,5-trihydroxybenzoate)
(2R,3R)-5,7-dihydroxy-2-(3,4,5-trihydroxyphenyl)-3,4-dihydro-2H-chromen-3-
(2R,3R)-5,7-dihydroxy-2-(3,4,5-trihydroxyphenyl)-3,4-dihydro-2H-chromen-3-yl 3,4,5-trihydroxybenzoate
50299_FLUKA
989-51-5
ACon1_001054
AIDS-000674
AIDS000674
Ambap721
ANTIOXIDANT MODEL (TRAMP) -EPIGALLOCATECHIN GALLATE
Benzoic acid, 3,4,5-trihydroxy-, (2R,3R)-3,4-dihydro-5,7-dihydroxy-2-(3,4,5-trihydroxyphenyl)-2H-1-benzopyran-3-yl ester
BSPBio_001628
C045651
C09731
C22H18O11
Catechin deriv.
CCRIS 3729
CHEBI:4806
CPD000449288
DivK1c_006373
E4143_SIAL
E4143_SIGMA
E4268_SIAL
E4268_SIGMA
EGCG
EGCG cpd
epigallo-catechin gallate
Epigallocatechin 3-gallate
Epigallocatechin gallate
Epigallocatechin-3-gallate
Epigallocatechol, 3-gallate, (-)-
Galloyl-L-epigallocatechol
Green tea extract
KBio1_001317
KBio2_000796
KBio2_003364
KBio2_005932
KBio3_001128
KBioGR_002002
KBioSS_000796
LMPK12030005
LS-2197
MEGxp0_001166
MLS000758300
MLS001424000
NCGC00164319-02
NCGC00164319-03
SAM001247031
SDCCGMLS-0066550.P001
SMR000449288
SPBio_000035
SpecPlus_000277
SPECTRUM210239
Spectrum2_000168
Spectrum3_000244
Spectrum4_001541
Spectrum5_000102
Spectrum_000316
Tea catechin
Teavigo
ZINC03870412

Target

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Uniprot ID:MET_HUMAN
Synonyms:
c-Met
Hepatocyte growth factor receptor
HGF receptor
HGF/SF receptor
Met proto-oncogene tyrosine kinase
Scatter factor receptor
SF receptor
EC-Numbers:2.7.10.1
Organism:Homo sapiens
Human
PDB IDs:1FYR 1R0P 1R1W 1SHY 1SSL 1UX3 2G15 2RFN 2RFS 2UZX 2UZY 2WD1 2WGJ 3BUX 3CE3 3CTH 3CTJ 3EFJ 3EFK 3F66 3F82
Structure:
3F82

Binding Affinities:

Ki: Kd:Ic 50:Ec50/Ic50:
--10000-
3300---

References: